
Professor Peter Gunning
Fields of research: Molecular Medicine, Cancer Cell Biology, Cell Development, Proliferation and Death, Biologically Active Molecules
Contact Details
Phone: 0408969082
Email: p.gunning@unsw.edu.au
Supervision
- PHD
- Masters
- Honours
Tabs
Publications related to this Person
Books
Gunning P, 2008, Preface
Book Chapters
Brayford S; Schevzov G; Vos J; Gunning P, 2015, 'The role of the actin cytoskeleton in cancer and its potential use as a therapeutic target', in The Cytoskeleton in Health and Disease, pp. 373 - 391, http://dx.doi.org/10.1007/978-1-4939-2904-7_16
Bonello T; Coombes J; Schevzov G; Gunning P; Stehn J, 2012, 'Therapeutic Targeting of the Actin Cytoskeleton in Cancer', in Kavallaris M (ed.), Cytoskeleton and Human Disease, pp. 181 - 200, http://dx.doi.org/10.1007/978-1-61779-788-0_10
Curthoys N; Gunning P; Fath T, 2011, 'Tropomyosins in neuronal morphogenesis and development', in Abel Lajtha (ed.), Cytoskeleton of the Nervous System, edn. Advances in Neurobiology, Springer, USA, pp. 411 - 446, http://dx.doi.org/10.1007/978-1-4419-6787-9_18
Gunning PW, 2006, 'Protein Isoforms and Isozymes', in , Wiley, http://dx.doi.org/10.1038/npg.els.0005717
Hill MA; Gunning P, 1995, 'The cell cytoskeleton's functional requirement for localized mRNA', in Localized RNAs, edn. Original, Springer Publishing Company, New York, pp. 197 - 213
Landreth GE; Sutter A; Yankner BA; Gunning PW; Shooter EM, 1981, 'MECHANISM OF ACTION OF NERVE GROWTH FACTOR1', in Cellular Responses to Molecular Modulators, Elsevier, pp. 205 - 217, http://dx.doi.org/10.1016/b978-0-12-509380-4.50017-x
Journal articles
Cagigas ML; Bryce NS; Ariotti N; Brayford S; Gunning PW; Hardeman EC, 2022, 'Correlative cryo-ET identifies actin/tropomyosin filaments that mediate cell–substrate adhesion in cancer cells and mechanosensitivity of cell proliferation', Nature Materials, vol. 21, pp. 120 - 128, http://dx.doi.org/10.1038/s41563-021-01087-z
Hardeman EC; Heydecker M; Masedunskas A; Ebrahim S; Weigert R; Gunning PW, 2022, 'Intravital subcellular and single molecule imaging reveals multiple actin filament populations collaborate in the remodelling of the secretory granule membrane', Biophysical Journal, vol. 121, pp. 297a - 298a, http://dx.doi.org/10.1016/j.bpj.2021.11.1268
Chaichim C; Tomanic T; Stefen H; Paric E; Gamaroff L; Suchowerska AK; Gunning PW; Ke YD; Fath T; Power J, 2021, 'Overexpression of tropomyosin isoform tpm3.1 does not alter synaptic function in hippocampal neurons', International Journal of Molecular Sciences, vol. 22, http://dx.doi.org/10.3390/ijms22179303
Xu X; Wang Y; Bryce NS; Tang K; Meagher NS; Kang EY; Kelemen LE; Köbel M; Ramus SJ; Friedlander M; Ford CE; Hardeman EC; Gunning PW, 2021, 'Targeting the actin/tropomyosin cytoskeleton in epithelial ovarian cancer reveals multiple mechanisms of synergy with anti-microtubule agents', British Journal of Cancer, vol. 125, pp. 265 - 276, http://dx.doi.org/10.1038/s41416-021-01420-y
Rae J; Ferguson C; Ariotti N; Webb RI; Cheng HH; Mead JL; Riches JD; Hunter DJB; Martel N; Baltos J; Christopoulos A; Bryce NS; Cagigas ML; Fonseka S; Sayre ME; Hardeman EC; Gunning PW; Gambin Y; Hall TE; Parton RG, 2021, 'A robust method for particulate detection of a genetic tag for 3D electron microscopy', eLife, vol. 10, http://dx.doi.org/10.7554/ELIFE.64630
Tomanić T; Martin C; Stefen H; Parić E; Gunning P; Fath T, 2021, 'Deletion of the actin‐associated tropomyosin tpm3 leads to reduced cell complexity in cultured hippocampal neurons—new insights into the role of the c‐terminal region of tpm3.1', Cells, vol. 10, http://dx.doi.org/10.3390/cells10030715
Rae J; Ferguson C; Ariotti N; Webb R; Cheng H-H; Mead J; Riches J; Hunter DJB; Martel N; Baltos J; Christopoulos A; Bryce N; Cagigas ML; Fonseka S; Hardeman E; Gunning P; Gambin Y; Hall T; Parton R, 2020, 'APEX-Gold: A genetically-encoded particulate marker for robust 3D electron microscopy', , http://dx.doi.org/10.1101/2020.10.06.328831
Janco M; Dedova I; Bryce NS; Hardeman EC; Gunning PW, 2020, 'Visualizing the in vitro assembly of tropomyosin/actin filaments using TIRF microscopy', Biophysical Reviews, vol. 12, pp. 879 - 885, http://dx.doi.org/10.1007/s12551-020-00720-6
Wang Y; Stear JH; Swain A; Xu X; Bryce NS; Carnell M; Alieva IB; Dugina VB; Cripe TP; Stehn J; Hardeman EC; Gunning PW, 2020, 'Drug targeting the actin cytoskeleton potentiates the cytotoxicity of low dose vincristine by abrogating actin-mediated repair of spindle defects', Molecular Cancer Research, vol. 18, pp. 1074 - 1087, http://dx.doi.org/10.1158/1541-7786.MCR-19-1122
Hardeman EC; Bryce NS; Gunning PW, 2020, 'Impact of the actin cytoskeleton on cell development and function mediated via tropomyosin isoforms', Seminars in Cell and Developmental Biology, vol. 102, pp. 122 - 131, http://dx.doi.org/10.1016/j.semcdb.2019.10.004
Abouelezz A; Stefen H; Segerstråle M; Micinski D; Minkeviciene R; Lahti L; Hardeman EC; Gunning PW; Hoogenraad CC; Taira T; Fath T; Hotulainen P, 2020, 'Tropomyosin Tpm3.1 Is Required to Maintain the Structure and Function of the Axon Initial Segment', iScience, vol. 23, http://dx.doi.org/10.1016/j.isci.2020.101053
Kumari R; Jiu Y; Carman PJ; Tojkander S; Kogan K; Varjosalo M; Gunning PW; Dominguez R; Lappalainen P, 2020, 'Tropomodulins Control the Balance between Protrusive and Contractile Structures by Stabilizing Actin-Tropomyosin Filaments', Current Biology, vol. 30, pp. 767 - 778.e5, http://dx.doi.org/10.1016/j.cub.2019.12.049
Manstein DJ; Meiring JCM; Hardeman EC; Gunning PW, 2020, 'Actin–tropomyosin distribution in non-muscle cells', Journal of Muscle Research and Cell Motility, vol. 41, pp. 11 - 22, http://dx.doi.org/10.1007/s10974-019-09514-0
Hardeman EC; Gunning PW, 2020, 'Life and death agendas of actin filaments', Nature Materials, vol. 19, pp. 135 - 136, http://dx.doi.org/10.1038/s41563-019-0583-1
Meiring JCM; Bryce NS; Niño JLG; Gabriel A; Tay SS; Hardeman EC; Biro M; Gunning PW, 2019, 'Tropomyosin concentration but not formin nucleators mDia1 and mDia3 determines the level of tropomyosin incorporation into actin filaments', Scientific Reports, vol. 9, http://dx.doi.org/10.1038/s41598-019-42977-2
Bryce NS; Failes TW; Stehn JR; Baker K; Zahler S; Arzhaeva Y; Bischof L; Lyons C; Dedova I; Arndt GM; Gaus K; Goult BT; Hardeman EC; Gunning PW; Lock JG, 2019, 'High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained', Cell Systems, vol. 9, pp. 496 - 507.e5, http://dx.doi.org/10.1016/j.cels.2019.09.002
Meiring JCM; Bryce NS; Lastra Cagigas M; Benda A; Whan RM; Ariotti N; Parton RG; Stear JH; Hardeman EC; Gunning PW, 2019, 'Colocation of Tpm3.1 and myosin IIa heads defines a discrete subdomain in stress fibres', Journal of cell science, vol. 132, http://dx.doi.org/10.1242/jcs.228916
Janco M; Rynkiewicz MJ; Li L; Hook J; Eiffe E; Ghosh A; Böcking T; Lehman WJ; Hardeman EC; Gunning PW, 2019, 'Molecular integration of the anti-tropomyosin compound ATM-3507 into the coiled coil overlap region of the cancer-associated Tpm3.1', Scientific reports, vol. 9, pp. 11262, http://dx.doi.org/10.1038/s41598-019-47592-9
Bryce NS; Hardeman EC; Gunning PW; Lock JG, 2019, 'Chemical biology approaches targeting the actin cytoskeleton through phenotypic screening', Current Opinion in Chemical Biology, vol. 51, pp. 40 - 47, http://dx.doi.org/10.1016/j.cbpa.2019.02.013
Ebrahim S; Chen D; Weiss M; Malec L; Ng Y; Rebustini I; Krystofiak E; Hu L; Liu J; Masedunskas A; Hardeman E; Gunning P; Kachar B; Weigert R, 2019, 'Dynamic polyhedral actomyosin lattices remodel micron-scale curved membranes during exocytosis in live mice', Nature Cell Biology, vol. 21, pp. 933 - 939, http://dx.doi.org/10.1038/s41556-019-0365-7
Kim TH; Ly C; Christodoulides A; Nowell CJ; Gunning PW; Sloan EK; Rowat AC, 2019, 'Stress hormone signaling through β-adrenergic receptors regulates macrophage mechanotype and function', FASEB Journal, vol. 33, pp. 3997 - 4006, http://dx.doi.org/10.1096/fj.201801429RR
Sao K; Jones TM; Doyle AD; Maity D; Schevzov G; Chen Y; Gunning PW; Petrie RJ, 2019, 'Myosin II governs intracellular pressure and traction by distinct tropomyosin-dependent mechanisms', Molecular Biology of the Cell, vol. 30, pp. 1170 - 1181, http://dx.doi.org/10.1091/mbc.E18-06-0355
Kee AJ; Chagan J; Chan JY; Bryce NS; Lucas CA; Zeng J; Hook J; Treutlein H; Laybutt DR; Stehn JR; Gunning PW; Hardeman EC, 2018, 'On-target action of anti-tropomyosin drugs regulates glucose metabolism', Scientific Reports, vol. 8, http://dx.doi.org/10.1038/s41598-018-22946-x
Meiring JCM; Bryce NS; Wang Y; Taft MH; Manstein DJ; Liu Lau S; Stear J; Hardeman EC; Gunning PW, 2018, 'Co-polymers of Actin and Tropomyosin Account for a Major Fraction of the Human Actin Cytoskeleton', Current Biology, vol. 28, pp. 2331 - 2337.e5, http://dx.doi.org/10.1016/j.cub.2018.05.053
Stefen H; Suchowerska AK; Chen BJ; Brettle M; Kuschelewski J; Gunning PW; Janitz M; Fath T, 2018, 'Tropomyosin isoforms have specific effects on the transcriptome of undifferentiated and differentiated B35 neuroblastoma cells', FEBS Open Bio, vol. 8, pp. 570 - 583, http://dx.doi.org/10.1002/2211-5463.12386
Gunning PW; Hardeman EC, 2018, 'Tropomyosin-directed tuning of myosin motor function: Insights from mutagenesis', Cytoskeleton, vol. 75, pp. 147 - 149, http://dx.doi.org/10.1002/cm.21441
Masedunskas A; Appaduray MA; Lucas CA; Cagigas ML; Heydecker M; Holliday M; Meiring JCM; Hook J; Kee A; White M; Thomas P; Zhang Y; Adelstein RS; Meckel T; Böcking T; Weigert R; Bryce NS; Gunning PW; Hardeman EC, 2018, 'Parallel assembly of actin and tropomyosin, but not myosin II, during de novo actin filament formation in live mice', Journal of Cell Science, vol. 131, http://dx.doi.org/10.1242/jcs.212654
Gunning PW; Hardeman EC, 2018, 'Fundamental differences', eLife, vol. 7, http://dx.doi.org/10.7554/eLife.34477
Suchowerska AK; Fok S; Stefen H; Gunning PW; Hardeman EC; Power J; Fath T, 2017, 'Developmental profiling of tropomyosin expression in mouse brain reveals Tpm4.2 as the major post-synaptic tropomyosin in the mature brain', Frontiers in Cellular Neuroscience, vol. 11, http://dx.doi.org/10.3389/fncel.2017.00421
Austin Elam W; Cao W; Kang H; Huehn A; Hocky GM; Prochniewicz E; Schramm AC; Negrón K; Garcia J; Bonello TT; Gunning PW; Thomas DD; Voth GA; Sindelar CV; De La Cruz EM, 2017, 'Phosphomimetic S3D cofilin binds but only weakly severs actin filaments', Journal of Biological Chemistry, vol. 292, pp. 19565 - 19579, http://dx.doi.org/10.1074/jbc.M117.808378
Nobis M; Herrmann D; Warren SC; Kadir S; Leung W; Killen M; Magenau A; Stevenson D; Lucas MC; Reischmann N; Vennin C; Conway JRW; Boulghourjian A; Zaratzian A; Law AM; Gallego-Ortega D; Ormandy CJ; Walters SN; Grey ST; Bailey J; Chtanova T; Quinn JMW; Baldock PA; Croucher PI; Schwarz JP; Mrowinska A; Zhang L; Herzog H; Masedunskas A; Hardeman EC; Gunning PW; del Monte-Nieto G; Harvey RP; Samuel MS; Pajic M; McGhee EJ; Johnsson AKE; Sansom OJ; Welch HCE; Morton JP; Strathdee D; Anderson KI; Timpson P, 2017, 'A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts', Cell Reports, vol. 21, pp. 274 - 288, http://dx.doi.org/10.1016/j.celrep.2017.09.022
Kee AJ; Bryce NS; Yang L; Polishchuk E; Schevzov G; Weigert R; Polishchuk R; Gunning PW; Hardeman EC, 2017, 'ER/Golgi trafficking is facilitated by unbranched actin filaments containing Tpm4.2', Cytoskeleton, vol. 74, pp. 379 - 389, http://dx.doi.org/10.1002/cm.21405
Currier MA; Stehn JR; Swain A; Chen D; Hook J; Eiffe E; Heaton A; Brown D; Nartker BA; Eaves DW; Kloss N; Treutlein H; Zeng J; Alieva IB; Dugina VB; Hardeman EC; Gunning PW; Cripe TP, 2017, 'Identification of cancer-targeted tropomyosin inhibitors and their synergy with microtubule drugs', Molecular Cancer Therapeutics, vol. 16, pp. 1555 - 1565, http://dx.doi.org/10.1158/1535-7163.MCT-16-0873
Desouza-Armstrong M; Gunning PW; Stehn JR, 2017, 'Tumor suppressor tropomyosin Tpm2.1 regulates sensitivity to apoptosis beyond anoikis characterized by changes in the levels of intrinsic apoptosis proteins', Cytoskeleton, vol. 74, pp. 233 - 248, http://dx.doi.org/10.1002/cm.21367
Gateva G; Kremneva E; Reindl T; Kotila T; Kogan K; Gressin L; Gunning PW; Manstein DJ; Michelot A; Lappalainen P, 2017, 'Tropomyosin Isoforms Specify Functionally Distinct Actin Filament Populations In Vitro', Current Biology, vol. 27, pp. 705 - 713, http://dx.doi.org/10.1016/j.cub.2017.01.018
Pleines I; Woods J; Chappaz S; Kew V; Foad N; Ballester-Beltrán J; Aurbach K; Lincetto C; Lane RM; Schevzov G; Alexander WS; Hilton DJ; Astle WJ; Downes K; Nurden P; Westbury SK; Mumford AD; Obaji SG; Collins PW; BioResource N; Delerue F; Ittner LM; Bryce NS; Holliday M; Lucas CA; Hardeman EC; Ouwehand WH; Gunning PW; Turro E; Tijssen MR; Kile BT, 2017, 'Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia', Journal of Clinical Investigation, vol. 127, pp. 814 - 829, http://dx.doi.org/10.1172/JCI86154
Gunning PW; Hardeman EC, 2017, 'Tropomyosins', Current Biology, vol. 27, pp. R8 - R13, http://dx.doi.org/10.1016/j.cub.2016.11.033
Jeong SY; Lim SY; Schevzov G; Gunning PW; Helfman DM, 2017, 'Loss of Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells via increased Rac1 signaling', Oncotarget, vol. 8, pp. 33544 - 33559, http://dx.doi.org/10.18632/oncotarget.16825
Desouza-Armstrong M; Gunning PW; Stehn JR, 2017, 'Cover Image, Volume 74, Issue 6', Cytoskeleton, vol. 74, pp. C4 - C4, http://dx.doi.org/10.1002/cm.21376
Desouza-Armstrong M; Gunning PW; Stehn JR, 2017, 'Cover Image, Volume 74, Issue 6', Cytoskeleton, vol. 74, pp. C1 - C1, http://dx.doi.org/10.1002/cm.21375
Kee AJ; Bryce NS; Yang L; Polishchuk E; Schevzov G; Weigert R; Polishchuk R; Gunning PW; Hardeman EC, 2017, 'Cover Image, Volume 74, Issue 10', Cytoskeleton, vol. 74, pp. C4 - C4, http://dx.doi.org/10.1002/cm.21413
Nicovich PR; Janco M; Sobey T; Gajwani M; Obeidy P; Whan R; Gaus K; Gunning PW; Coster ACF; Böcking T, 2016, 'Effect of surface chemistry on tropomyosin binding to actin filaments on surfaces', Cytoskeleton, vol. 73, pp. 729 - 738, http://dx.doi.org/10.1002/cm.21342
Appaduray MA; Masedunskas A; Bryce NS; Lucas CA; Warren SC; Timpson P; Stear JH; Gunning PW; Hardeman EC, 2016, 'Recruitment kinetics of tropomyosin tpm3.1 to actin filament bundles in the cytoskeleton is independent of actin filament kinetics', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0168203
Gunning P; Shivashankar GV, 2016, 'Letter from the editors', BioArchitecture, vol. 6, pp. 105, http://dx.doi.org/10.1080/19490992.2016.1291050
Chen Y; Gu M; Gunning PW; Russell SM, 2016, 'Dense small molecule labeling enables activator-dependent STORM by proximity mapping', Histochemistry and Cell Biology, vol. 146, pp. 255 - 266, http://dx.doi.org/10.1007/s00418-016-1451-6
Janco M; Bonello TT; Byun A; Coster ACF; Lebhar H; Dedova I; Gunning PW; Böcking T, 2016, 'The impact of tropomyosins on actin filament assembly is isoform specific', BioArchitecture, vol. 6, pp. 61 - 75, http://dx.doi.org/10.1080/19490992.2016.1201619
Brayford S; Bryce NS; Schevzov G; Haynes EM; Bear JE; Hardeman EC; Gunning PW, 2016, 'Tropomyosin promotes lamellipodial persistence by collaborating with Arp2/3 at the leading edge', Current Biology, vol. 26, pp. 1312 - 1318, http://dx.doi.org/10.1016/j.cub.2016.03.028
Bonello TT; Janco M; Hook J; Byun A; Appaduray M; Dedova I; Hitchcock-DeGregori S; Hardeman EC; Stehn JR; Böcking T; Gunning PW, 2016, 'A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep19816
Erami Z; Herrmann D; Warren SC; Nobis M; McGhee EJ; Lucas MC; Leung W; Reischmann N; Mrowinska A; Schwarz JP; Kadir S; Conway JRW; Vennin C; Karim SA; Campbell AD; Gallego-Ortega D; Magenau A; Murphy KJ; Ridgway RA; Law AM; Walters SN; Grey ST; Croucher DR; Zhang L; Herzog H; Hardeman EC; Gunning PW; Ormandy CJ; Evans TRJ; Strathdee D; Sansom OJ; Morton JP; Anderson KI; Timpson P, 2016, 'Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue', Cell Reports, vol. 14, pp. 152 - 167, http://dx.doi.org/10.1016/j.celrep.2015.12.020
Kee AJ; Yang L; Lucas CA; Greenberg MJ; Martel N; Leong GM; Hughes WE; Cooney GJ; James DE; Ostap EM; Han W; Gunning PW; Hardeman EC, 2016, 'Corrigendum to An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake [Traic, (2015), 16, 7, 691-711]', Traffic, vol. 17, pp. 80 - 81, http://dx.doi.org/10.1111/tra.12342
Dugina V; Alieva I; Khromova N; Kireev I; Gunning PW; Kopnin P, 2016, 'Interaction of microtubules with the actin cytoskeleton via cross-talk of EB1-containing +TIPs and γ-actin in epithelial cells', Oncotarget, vol. 7, pp. 72699 - 72715, http://dx.doi.org/10.18632/oncotarget.12236
Knothe Tate ML; Gunning PW; Sansalone V, 2016, 'Emergence of form from function: role of stem cell mechanoadaptation in sealing of cell fate', Bioarchitecture, vol. 6, pp. 85 - 103, http://dx.doi.org/10.1080/19490992.2016.1229729
Coombes JD; Schevzov G; Kan CY; Petti C; Maritz MF; Whittaker S; Mackenzie KL; Gunning PW, 2015, 'Ras Transformation Overrides a Proliferation Defect Induced by Tpm3.1 Knockout', Cellular and Molecular Biology Letters, vol. 20, pp. 626 - 646, http://dx.doi.org/10.1515/cmble-2015-0037
Glass JJ; Phillips PA; Gunning PW; Stehn JR, 2015, 'Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells', BMC Cancer, vol. 15, http://dx.doi.org/10.1186/s12885-015-1741-8
Gunning PW; Hardeman EC; Lappalainen P; Mulvihill DP, 2015, 'Tropomyosin - master regulator of actin filament function in the cytoskeleton', Journal of Cell Science, vol. 128, pp. 2965 - 2974, http://dx.doi.org/10.1242/jcs.172502
Kee AJ; Yang L; Lucas CA; Greenberg MJ; Martel N; Leong GM; Hughes WE; Cooney GJ; James DE; Ostap EM; Han W; Gunning PW; Hardeman EC, 2015, 'An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake', Traffic, vol. 16, pp. 691 - 711, http://dx.doi.org/10.1111/tra.12282
Canales CP; Wong ACY; Gunning PW; Housley GD; Hardeman EC; Palmer SJ, 2015, 'The role of GTF2IRD1 in the auditory pathology of Williams-Beuren Syndrome', European Journal of Human Genetics, vol. 23, pp. 774 - 780, http://dx.doi.org/10.1038/ejhg.2014.188
Prunotto M; Bruschi M; Gunning P; Gabbiani G; Weibel F; Ghiggeri GM; Petretto A; Scaloni A; Bonello T; Schevzov G; Alieva I; Bochaton-Piallat ML; Candiano G; Dugina V; Chaponnier C, 2015, 'Stable incorporation of α-smooth muscle actin into stress fibers is dependent on specific tropomyosin isoforms', Cytoskeleton, vol. 72, pp. 257 - 267, http://dx.doi.org/10.1002/cm.21230
Jalilian I; Heu C; Cheng H; Freittag H; Desouza M; Stehn JR; Bryce NS; Whan RM; Hardeman EC; Fath T; Schevzov G; Gunning PW, 2015, 'Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0126214
Schevzov G; Kee AJ; Wang B; Sequeira VB; Hook J; Coombes JD; Lucas CA; Stehn JR; Musgrove EA; Cretu A; Assoian R; Fath T; Hanoch T; Seger R; Pleines I; Kile BT; Hardeman EC; Gunning PW, 2015, 'Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments', Molecular Biology of the Cell, vol. 26, pp. 2475 - 2490, http://dx.doi.org/10.1091/mbc.E14-10-1453
Geeves MA; Hitchcock-DeGregori SE; Gunning PW, 2015, 'A systematic nomenclature for mammalian tropomyosin isoforms', Journal of Muscle Research and Cell Motility, vol. 36, pp. 147 - 153, http://dx.doi.org/10.1007/s10974-014-9389-6
Gunning PW; Ghoshdastider U; Whitaker S; Popp D; Robinson RC, 2015, 'The evolution of compositionally and functionally distinct actin filaments', Journal of Cell Science, vol. 128, pp. 2009 - 2019, http://dx.doi.org/10.1242/jcs.165563
Hu M; Kramer B; Zhang GY; Wang YM; Watson D; Howden B; McCowage G; Alexander IE; Gunning P; Alexander SI, 2015, 'Methyl-guanine-methyl-transferase transgenic bone marrow transplantation allows N, N-bis (2-chloroethyl)-nitrosourea driven donor mixed-chimerism without graft-versus-host disease, and with donor-specific allograft tolerance', Transplantation, vol. 99, pp. 2476 - 2484, http://dx.doi.org/10.1097/TP.0000000000000825
Lim CY; Bi X; Wu D; Kim JB; Gunning PW; Hong W; Han W, 2015, 'Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling', Nature Communications, vol. 6, http://dx.doi.org/10.1038/ncomms6951
Hardeman EC; Appaduray MA; Masedunskas A; Bryce NS; Lucas CA; Gunning PW, 2015, 'Recruitment kinetics of tropomyosin is independent of actin filaments', MOLECULAR BIOLOGY OF THE CELL, vol. 26, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209928500840&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Bryce NS; De Laurentiis A; Failes T; Arndt GM; Stehn JR; Hardeman EC; Gunning PW, 2015, 'Identification of the possible states of organisation of the actin cytoskeleton using high content image screening of a high diversity chemical library.', MOLECULAR BIOLOGY OF THE CELL, vol. 26, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209928400229&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Pleines I; Woods J; Turro E; Foad N; Chappaz S; Lane RM; Manning H; Schevzov G; Westbury SK; Mumford AD; Favier R; Gunning P; Ouwehand WH; Tijssen MR; Kile BT, 2014, 'Mutations in Tropomyosin 4 Cause Macrothrombocytopenia in Mice and Humans', BLOOD, vol. 124, http://dx.doi.org/10.1182/blood.V124.21.571.571
Caldwell BJ; Lucas C; Kee AJ; Gaus K; Gunning PW; Hardeman EC; Yap AS; Gomez GA, 2014, 'Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens', Cytoskeleton, vol. 71, pp. 663 - 676, http://dx.doi.org/10.1002/cm.21202
Stehn JR; Chen D; Currier MA; Eaves D; Desouza M; Moosavian M; Cripe TP; Gunning PW, 2014, 'Synergistic anti-neuroblastoma efficacy using combinatorial cytoskeletal inhibitors', CANCER RESEARCH, vol. 74, http://dx.doi.org/10.1158/1538-7445.PEDCAN-B50
Vindin H; Bischof L; Gunning P; Stehn J, 2014, 'Validation of an algorithm to quantify changes in actin cytoskeletal organization', Journal of Biomolecular Screening, vol. 19, pp. 354 - 368, http://dx.doi.org/10.1177/1087057113503494
Curthoys NM; Freittag H; Connor A; Desouza M; Brettle M; Poljak A; Hall A; Hardeman E; Schevzov G; Gunning PW; Fath T, 2014, 'Tropomyosins induce neuritogenesis and determine neurite branching patterns in B35 neuroblastoma cells', Molecular and Cellular Neuroscience, vol. 58, pp. 11 - 21, http://dx.doi.org/10.1016/j.mcn.2013.10.011
Masedunskas A; Appaduray M; Gunning PW; Hardeman EC, 2014, 'Lighting up microtubule cytoskeleton dynamics in skeletal muscle', IntraVital, vol. 3, pp. e29293-1-e29293-5, http://dx.doi.org/10.4161/intv.29293
Desouza M; Nguyen M; Gunning PW; Stehn JR, 2013, 'Targeting the actin cytoskeleton of neuroblastoma: Elucidating the mechanism by which a novel class of anti-cancer compounds induces tumor cell death.', MOLECULAR CANCER THERAPEUTICS, vol. 12, http://dx.doi.org/10.1158/1535-7163.TARG-13-C208
Koestler SA; Steffen A; Nemethova M; Winterhoff M; Luo N; Holleboom JM; Krupp J; Jacob S; Vinzenz M; Schur F; Schlüter K; Gunning PW; Winkler C; Schmeiser C; Faix J; Stradal TEB; Small JV; Rottner K, 2013, 'Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin', Molecular Biology of the Cell, vol. 24, pp. 2861 - 2875, http://dx.doi.org/10.1091/mbc.E12-12-0857
Vindin H; Gunning P, 2013, 'Cytoskeletal tropomyosins: Choreographers of actin filament functional diversity', Journal of Muscle Research and Cell Motility, vol. 34, pp. 261 - 274, http://dx.doi.org/10.1007/s10974-013-9355-8
Pleines I; Chappaz S; Lane R; Kostadima MA; Schevzov G; Ghevaert C; Gunning P; Ouwehand WH; Kile BT, 2013, 'Tropomyosin 4 is a novel regulator of platelet production in mice and humans', JOURNAL OF THROMBOSIS AND HAEMOSTASIS, vol. 11, pp. 159 - 160, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000331833601360&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Schevzov G; Kee A; Hook J; Pleines I; Kile B; Hardeman E; Gunning P, 2013, 'Distinct actin filament networks modulate different cell signaling cascades', MOLECULAR BIOLOGY OF THE CELL, vol. 24, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348702022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Kee AJ; Tran L; Yang L; Genel F; Weigert R; Gunning P; Hardeman E, 2013, 'Identification of a novel Golgi-associated actin filament population that is important for maintaining Golgi morphology', MOLECULAR BIOLOGY OF THE CELL, vol. 24, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348702023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Suchowerska A; Chen B; Mueller J; Ittner A; Hardeman E; Ittner L; Janitz M; Gunning P; Fath T, 2013, 'Increased levels of actin filaments containing the tropomyosin Tm5NM1 regulate excitotoxicity in the mouse', MOLECULAR BIOLOGY OF THE CELL, vol. 24, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348702020&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Wang B; Schevzov G; Coombes J; Hook J; Kee A; Lucas C; Stehn J; Sequeira V; Seger R; Hardeman E; Gunning P, 2013, 'Regulation of cell proliferation mediated by the actin filament regulator Tropomyosin 5NM1', MOLECULAR BIOLOGY OF THE CELL, vol. 24, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348702025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Masedunskas A; Appaduray M; Hardeman EC; Gunning PW, 2013, 'What makes a model system great?: A case for intravital microscopy for studying the actin cytoskeleton', IntraVital, vol. 2, pp. 1 - 9, http://dx.doi.org/10.4161/intv.26287
Lees JG; Ching YW; Adams DH; Bach CT; Samuel MS; Kee AJ; Hardeman EC; Gunning P; Cowin AJ; O'Neill GM, 2013, 'Tropomyosin regulates cell migration during skin wound healing', Journal of Investigative Dermatology, vol. 133, pp. 1330 - 1339, http://dx.doi.org/10.1038/jid.2012.489
Stehn JR; Haass NK; Bonello T; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PR; Sequeira VB; Butler TL; Allanson M; Fath T; Hill TA; McCluskey A; Schevzov G; Palmer S; Hardeman EC; Winlaw D; Reeve VE; Dixon I; Weninger W; Cripe TP; Gunning PW, 2013, 'A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells', Cancer research, vol. 73, pp. 5169 - 5182, http://dx.doi.org/10.1158/0008-5472.CAN-12-4501
Lee AS; Anderson JE; Joya JE; Head SI; Pather N; Kee AJ; Gunning PW; Hardeman EC, 2013, 'Aged skeletal muscle retains the ability to fully regenerate functional architecture', BioArchitecture, vol. 3, pp. 25 - 37, http://dx.doi.org/10.4161/bioa.24966
Gunning P, 2013, 'Welcome to BioArchitecture 2013', BioArchitecture, vol. 3, pp. 1 - 1, http://dx.doi.org/10.4161/bioa.24027
Schevzov G; Coombes J; Hook J; Wang B; Kee A; Lucas C; Szokolai R; Sequeira V; Stehn J; Musgrove E; Hardeman E; Gunning P, 2012, 'Regulation of cell proliferation mediated by the actin filament stabilizing protein, Tropomyosin 5NM1.', MOLECULAR BIOLOGY OF THE CELL, vol. 23, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348601219&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Angrisano F; Riglar D; Sturm A; Volz J; Delves MJ; Zuccala E; Turnbull L; Dekiwadia C; Olshina MA; Marapana DS; Wong W; Mollard V; Bradin CH; Tonkin CJ; Gunning P; Ralph SA; Whitchurch CB; Sinden RE; Cowman AF; McFadden GI; Baum J, 2012, 'Spatial localisation of actin filaments across developmental stages of the malaria parasite', PLoS ONE, vol. 7, pp. Article number e32188, http://dx.doi.org/10.1371/journal.pone.0032188
Widagdo J; Taylor KM; Gunning PW; Hardeman EC; Palmer SJ, 2012, 'SUMOylation of GTF2IRD1 regulates protein partner interactions and ubiquitin-mediated degradation', PLoS ONE, vol. 7, pp. e49283 pg 1 - e49283 pg 10, http://dx.doi.org/10.1371/journal.pone.0049283
Palmer SJ; Taylor KM; Santucci N; Widagdo J; Chan Y-KA; Yeo J-L; Gunning PW; Hardeman EC, 2012, 'GTF2IRD2 from the Williams-Beuren critical region encodes a mobile element-derived fusion protein that antagonizes the action of its related family members', Journal of Cell Science, vol. 125, pp. 5040 - 5050, http://dx.doi.org/10.1242/​jcs.102798
Schevzov G; Curthoys NM; Gunning P; Fath T, 2012, 'Chapter Two – Functional Diversity of Actin Cytoskeleton in Neurons and its Regulation by Tropomyosin', International Review of Cell and Molecular Biology, vol. 298, pp. 33 - 94, http://dx.doi.org/10.1016/B978-0-12-394309-5.00002-X
Gunning P, 2012, 'The organization and regulation of biological space', BioArchitecture, vol. 2, pp. 200 - 203, http://dx.doi.org/10.4161/bioa.22726
Desouza M; Gunning P; Stehn JR, 2012, 'The actin cytoskeleton as a sensor and mediator of apoptosis', BioArchitecture, vol. 23, pp. 75 - 87, http://dx.doi.org/10.4161/bioa.20975
Gunning P, 2012, 'A reflection on 2011 and looking forward to 2012', BioArchitecture, vol. 2, pp. 1-1, http://dx.doi.org/10.4161/bioa.20320
Gunning P, 2011, 'Welcome to the first issue of Bioarchitecture', BioArchitecture, vol. 1, pp. 1, http://dx.doi.org/10.4161/bioa.1.1.15419
Nguyen MA; Joya JE; Kee AJ; Domazetovska A; Yang N; Hook JW; Lemckert FA; Kettle E; Valova VA; Robinson PJ; North KN; Gunning PW; Mitchell CA; Hardeman EC, 2011, 'Hypertrophy and dietary tyrosine ameliorate the phenotypes of a mouse model of severe nemaline myopathy.', Brain, vol. 134, pp. 3513 - 3526, http://dx.doi.org/10.1093/brain/awr274
Lees JG; Bach CT; Bradbury P; Paul A; Gunning P; O'neill G, 2011, 'The actin-associating protein Tm5NM1 blocks mesenchymal motility without transition to amoeboid motility', Oncogene, vol. 30, pp. 1241 - 1251, http://dx.doi.org/10.1038/onc.2010.516
Creed S; Desouza M; Bamburg J; Gunning P; Stehn J, 2011, 'Tropomyosin isoform 3 promotes the formation of filopodia by regulating the recruitment of actin-binding proteins to actin filaments', Experimental Cell Research, vol. 317, pp. 249 - 261, http://dx.doi.org/10.1016/j.yexcr.2010.10.019
Tojkander S; Gateva G; Schevzov G; Hotulainen P; Naumanen P; Martin C; Gunning P; Lappalainen P, 2011, 'A Molecular Pathway for Myosin II Recruitment to Stress Fibers', Current Biology, vol. 21, pp. 539 - 550, http://dx.doi.org/10.1061/j.cub.2011.03.007
Gallant C; Appel S; Graceffa P; Leavis P; Lin JJ-C; Gunning P; Schevzov G; Chaponnier C; DeGnore J; Lehman W; Morgan K, 2011, 'Tropomyosin variants describe distinct functional subcellular domains in differentiated vascular smooth muscle cells', American Journal of Physiology - Cell Physiology, vol. 300, pp. 1356 - 1365, http://dx.doi.org/10.1152/ajpcell.00450.2010
Shum M; Pasquier E; Po'uha ST; O'Neill GM; Chaponnier C; Gunning PW; Kavallaris M, 2011, 'γ-Actin regulates cell migration and modulates the ROCK signaling pathway', The FASEB Journal, vol. 25, pp. 4423 - 4433, http://dx.doi.org/10.1096/fj.11-185447
Gunning P; Fath T; Guven K, 2011, 'TPM3 and TPM4 gene products segregate to the postsynaptic region of central nervous system synapses', BioArchitecture, vol. 1, pp. 284 - 289, http://dx.doi.org/10.4161/bioa.1.6.19336
Schevzov G; Whittaker S; Fath T; Lin JJC; Gunning P, 2011, 'Everything you need to know about: Tropomyosin Isoforms and Reagents', BioArchitecture, vol. 1, pp. 135 - 164, http://dx.doi.org/10.4161/bioa/1.4.17897
Hook J; Lemckert F; Schevzov G; Fath T; Gunning P, 2011, 'Functional identity of the gamma tropomyosin gene: Implications for embryonic development, reproduction and cell viability', BioArchitecture, vol. 1, pp. 49 - 59, http://dx.doi.org/10.4161/bioa.1.1.15172
Palmer SJ; Santucci N; Widagdo J; Bontempo SJ; Tay ES; Hook J; Lemckert F; Gunning PW; Hardeman EC, 2010, 'Negative autoregulation of GTF2IRD1 in Williams-Beuren syndrome via a novel DNA binding mechanism', The Journal of Biological Chemistry, vol. 285, pp. 4715 - 4724, http://dx.doi.org/10.1074/jbc.M109.086660
Fath T; Chan Y; Vrhovski B; Clarke H; Curthoys N; Hook J; Lemckert F; Schevzov G; Tam P; Watson C; Khoo P; Gunning P, 2010, 'New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2', European Journal of Cell Biology, vol. 89, pp. 489 - 498, http://dx.doi.org/10.1016/j.ejcb.2009.11.028
Martin C; Schevzov G; Gunning P, 2010, 'Alternatively spliced N-terminal exons in tropomyosin isoforms do not act as autonomous targeting signals', Journal of Structural Biology, vol. 170, pp. 286 - 293, http://dx.doi.org/10.1016/j.jsb.2009.12.016
Bach CT; Schevzov G; Bryce NS; Gunning P; O''neill G, 2010, 'Tropomyosin isoform modulation of focal adhesion structure and cell migration', Cell Adhesion and Migration, vol. 4, pp. 1 - 9, http://dx.doi.org/10.4161/cam.4.2.10888
Irimia M; Gunning P; Maeso I; Garcia-Fernandez J; Roy SW, 2010, 'Internal and external paralogy in the evolution of Tropomyosin genes in metazoans', Molecular Biology and Evolution, vol. 27, pp. 1504 - 1517, http://dx.doi.org/10.1093/molbev/msq018
Hu M; Kramer B; Howden B; Zhang G; Wang YM; McCowage G; Alexander I; Gunning P; Alexander SI, 2010, 'ALLOGRAFT TOLERANCE IN MICE WITH MGMT CHIMERIC BONE MARROW ENGRAFTMENT', Transplantation Journal, vol. 90, pp. 233 - 233, http://dx.doi.org/10.1097/00007890-201007272-00441
Lee AS; Kahatapitiya P; Kramer B; Joya JE; Hook J; Liu R; Schevzov G; Alexander IE; McCowage G; Montarras D; Gunning PW; Hardeman EC, 2009, 'Methylguanine DNA methyltransferase-mediated drug resistance-based selective enrichment and engraftment of transplanted stem cells in skeletal muscle', Stem Cells, vol. 27, pp. 1098 - 1108, http://dx.doi.org/10.1002/stem.28
Kee AJ; Gunning PW; Hardeman EC, 2009, 'A cytoskeletal tropomyosin can compromise the structural integrity of skeletal muscle', Cell Motility and the Cytoskeleton, vol. 66, pp. 710 - 720, http://dx.doi.org/10.1002/cm.20400
Kee AJ; Gunning PW; Hardeman EC, 2009, 'Diverse roles of the actin cytoskeleton in striated muscle', Journal of Muscle Research and Cell Motility, vol. 30, pp. 187 - 197, http://dx.doi.org/10.1007/s10974-009-9193-x
Vlahovich N; Kee AJ; Van der Poel C; Kettle E; Hernandez-Deviez D; Lucas C; Lynch GS; Parton RG; Gunning PW; Hardeman EC, 2009, 'Cytoskeletal tropomyosin Tm5NM1 is required for normal Excitation- contraction coupling in skeletal muscle', Molecular Biology of the Cell, vol. 20, pp. 400 - 409, http://dx.doi.org/10.1091/mbc.E08-06-0616
Schevzov G; Fath T; Gunning P, 2009, 'Intracellular structural compartments, disease and tropomyosins', Current Topics in Pharmacology, vol. 13, pp. 1 - 15
Fath T; Ke YD; Gunning P; Gotz J; Ittner LM, 2009, 'Primary support cultures of hippocampal and substantia nigra neurons', Nature Protocols, vol. 4, pp. 78 - 85, http://dx.doi.org/10.1038/nprot.2008.199
Bonello T; Stehn J; Gunning P, 2009, 'New approaches to targeting the actin cytoskeleton for chemotherapy.', Future Medicinal Chemistry, vol. 1, pp. 1311 - 1331, http://dx.doi.org/10.4155/fmc.09.99
Bach CT; Creed S; Zhong J; Mahmassani M; Schevzov G; Stehn J; Cowell L; Naumanen P; Lappalainen P; Gunning P; O''neill G, 2009, 'Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction', Molecular and Cellular Biology, vol. 29, pp. 1506 - 1514, http://dx.doi.org/10.1128/MCB.00857-08
Gunning P, 2008, 'Emerging issues for tropomyosin structure, regulation, function and pathology', Advances in Experimental Medicine and Biology, vol. 644, pp. 293 - 298, http://dx.doi.org/10.1007/978-0-387-85766-4_22
Martin C; Gunning P, 2008, 'Isoform sorting of tropomyosins', Advances in Experimental Medicine and Biology, vol. 644, pp. 187 - 200, http://dx.doi.org/10.1007/978-0-387-85766-4_15
Gunning P, 2008, 'Introduction and historical perspective', Advances in Experimental Medicine and Biology, vol. 644, pp. 1 - 5, http://dx.doi.org/10.1007/978-0-387-85766-4_1
Creed SJ; Bryce N; Naumanen P; Weinberger R; Lappalainen P; Stehn J; Gunning P, 2008, 'Tropomyosin isoforms define distinct microfilament populations with different drug susceptibility', European Journal of Cell Biology, vol. 87, pp. 709 - 720, http://dx.doi.org/10.1016/j.ejcb.2008.03.004
MacArthur DG; Seto JT; Chan S; Quinlan KG; Raftery JM; Turner N; Nicholson MD; Kee AJ; Hardeman EC; Gunning PW; Cooney GJ; Head SI; Yang N; North KN, 2008, 'An Actn3 knockout mouse provides mechanistic insights into the association between alpha-actinin-3 deficiency and human athletic performance', Human Molecular Genetics, vol. 17, pp. 1076 - 1086, http://dx.doi.org/10.1093/hmg/ddm380
Thoms J; Loch H; Bamburg J; Gunning P; Weinberger R, 2008, 'A tropomyosin 1 induced defect in cytokinesis can be rescued by elevated expression of cofilin', Cell Motility and the Cytoskeleton, vol. 65, pp. 979 - 990, http://dx.doi.org/10.1002/cm.20320
Ittner LM; Fath T; Ke YD; Bi M; van Eersel J; Li KM; Gunning P; Gotz J, 2008, 'Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia', Proceedings of the National Academy of Sciences of the United States of America, vol. 105, pp. 15997 - 16002, http://dx.doi.org/10.1073/pnas.0808084105
Schevzov G; Fath T; Vrhovski B; Vlahovich N; Rajan S; Hook J; Joya JE; Lemckert F; Puttur F; Lin JJ; Hardeman EC; Wieczorek DF; O'Neill GM; Gunning PW, 2008, 'Divergent regulation of the sarcomere and the cytoskeleton', The Journal of Biological Chemistry, vol. 283, pp. 275 - 283, http://dx.doi.org/10.1074/jbc.M704392200
Vlahovich N; Schevzov G; Nair-Shaliker V; Ilkovski B; Artap ST; Kee AJ; North KN; Gunning PW; Hardeman EC, 2008, 'Tropomyosin 4 defines novel filaments in skeletal muscle associated with muscle remodelling/regeneration in normal and diseased muscle', Cell Motility and the Cytoskeleton, vol. 65, pp. 73 - 85, http://dx.doi.org/10.1002/cm.20245
Chang AC; Hook J; Lemckert FA; McDonald M; Nguyen MA; Hardeman EC; Little DG; Gunning PW; Reddel RR, 2008, 'The murine stanniocalcin 2 gene is a negative regulator of postnatal growth', Endocrinology, vol. 149, pp. 2403 - 2410, http://dx.doi.org/10.1210/en.2007-1219
Gunning PW; O'Neill G; Hardeman EC, 2008, 'Tropomyosin-based regulation of the actin cytoskeleton in time and space', Physiological Reviews, vol. 88, pp. 1 - 35, http://dx.doi.org/10.1152/physrev.00001.2007
Ittner LM; Ke YD; Fath T; Schonrock N; Gunning P; Gotz J, 2008, 'P2‐129: Parkinsonism and memory impairment in tau transgenic mice with axonal transport defects', Alzheimer's & Dementia, vol. 4, pp. T408 - T408, http://dx.doi.org/10.1016/j.jalz.2008.05.1202
Ke YD; Ittner LM; Gunning P; Gotz J; Fath T, 2008, 'P1‐142: A new neurotrophic support culture technique for primary neurons', Alzheimer's & Dementia, vol. 4, pp. T248 - T248, http://dx.doi.org/10.1016/j.jalz.2008.05.729
Palmer SJ; Tay ES; Santucci N; Cuc Bach TT; Hook J; Lemckert FA; Jamieson RV; Gunning PW; Hardeman EC, 2007, 'Expression of Gtf2ird1, the Williams syndrome-associated gene during mouse development', Gene Expression Patterns, vol. 7, pp. 396 - 404, http://dx.doi.org/10.1016/j.modgep.2006.11.008
MacArthur DG; Seto JT; Raftery JM; Quinlan KG; Huttley GA; Hook JW; Lemckert FA; Kee AJ; Edwards MR; Berman Y; Hardeman EC; Gunning PW; Easteal S; Yang N; North KN, 2007, 'Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans', Nature Genetics, vol. 39, pp. 1261 - 1265, http://dx.doi.org/10.1038/ng2122
O Neill GM; Stehn J; Gunning P, 2007, 'Tropomyosins as interpreters of the signalling environment to regulate the local cytoskeleton', Seminars in Cancer Biology, vol. 18, pp. 35 - 44, http://dx.doi.org/10.1016/j.semcancer.2007.08.004
Domazetovska A; Ilkovski B; Cooper ST; Ghoddusi M; Hardeman EC; Minamide LS; Gunning PW; Bamburg JR; North K, 2007, 'Mechanisms underlying intranuclear rod formation', Brain, vol. 130, pp. 3275 - 3284, http://dx.doi.org/10.1093/brain/awm247
Kramer BA; Lemckert FA; Alexander IE; Gunning PW; McCowage GB, 2006, 'Characterisation of a P140K mutant O6- methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow', Journal of Gene Medicine, vol. 8, pp. 1071 - 1085, http://dx.doi.org/10.1002/jgm.937
Pouha ST; Liu M; Marshall GM; Kavallaris M; Verrills NM, 2006, 'Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia', Journal of the National Cancer Institute, vol. 98, pp. 1363 - 1374, http://dx.doi.org/10.1093/jnci/djj372
Stehn J; Schevzov G; O''neill G; Gunning P, 2006, 'Specialisation of the tropomyosin composition of actin filaments provides new potential targets for chemotherapy.', Current Cancer Drug Targets, vol. 6, pp. 245 - 256, http://dx.doi.org/10.2174/156800906776842948
Bargon SD; Gunning PW; O'Neill GM, 2005, 'The Cas family docking protein, HEF1, promotes the formation of neurite-like membrane extensions', Biochimica et Biophysica Acta - Molecular Cell Research, vol. 1746, pp. 143 - 154, http://dx.doi.org/10.1016/j.bbamcr.2005.10.008
Vlahovich N; Elmir S; Schevzov G; Kee A; Gunning P; Hardeman E, 2005, 'Non-muscle tropomyosins define functionally distinct microfilament populations in developing skeletal muscle', MECHANISMS OF DEVELOPMENT, vol. 122, pp. S49 - S49, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100178&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hook J; Vrhovski B; Lemckert F; Borovina T; Schevzov G; Gunning P, 2005, 'Alternative exon choice in the gamma tropomyosin (Tm) gene during development is not absolutely programmed', MECHANISMS OF DEVELOPMENT, vol. 122, pp. S159 - S159, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100601&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Vrhovski B; Mckay K; Schevzov G; Gunning P, 2005, 'Smooth muscle specific a tropomyosin is a marker of fully differentiated smooth muscle in lung.', Histochemical Journal, vol. 53, pp. 1 - 15, http://dx.doi.org/10.1369/jhc.4A6504.2005
Schevzov G; Bryce NS; Almonte-Baldonado R; Joya J; Lin JJ; Hardeman E; Weinberger R; Gunning P, 2005, 'Specific features of neuronal size and shape are regulated by tropomyosin isoforms.', Molecular Biology of the Cell, vol. 16, pp. 3425 - 3437, http://dx.doi.org/10.1091/mbc.E04-10-0951
Gunning PW; Schevzov G; Kee AJ; Hardeman EC, 2005, 'Tropomyosin isoforms: divining rods for actin cytoskeleton function', Trends in Cell Biology, vol. 15, pp. 333 - 341, http://dx.doi.org/10.1016/j.tcb.2005.04.007
Schevzov G; Vrhovski B; Bryce N; Elmir S; Qiu M; O''neill G; Yang N; Verrills N; Kavallaris M; Gunning P, 2005, 'Tissue-specific tropomyosin isoform composition.', Histochemical Journal, vol. 53, pp. 557 - 570, http://dx.doi.org/10.1369/jhc.4A6505.2005
Corbett MA; Akkari AP; Domazetovska A; Cooper ST; North K; Laing NG; Gunning PW; Hardeman EC, 2005, 'An alphatropomyosin mutation alters dimer preference in nemaline myopathy', Annals of Neurology, vol. 57, pp. 42 - 49, http://dx.doi.org/10.1002/ana.20305
Vrhovski B; Lemckert F; Gunning P, 2004, 'Modification of the tropomyosin isoform composition of actin filaments in the brain by deletion of an alternatively spliced exon', Neuropharmacology, vol. 47, pp. 684 - 693, http://dx.doi.org/10.1016/j.neuropharm.2004.07.011
Ashworth SL; Wean SE; Campos SB; Temm-Grove CJ; Southgate EL; Vrhovski B; Gunning P; Weinberger RP; Molitoris BA, 2004, 'Renal ischemia induces tropomyosin dissociation-destabilizing microvilli microfilaments', American Journal of Physiology - Renal Physiology, vol. 286, http://dx.doi.org/10.1152/ajprenal.00168.2003
Kee AJ; Schevzov G; Nair-shaliker V; Robinson C; Vrhovski B; Ghoddusi M; Qiu M; Lin JJ; Weinberger R; Gunning P; Hardeman E, 2004, 'Sorting of a nonmuscle tropomyosin to a novel cytoskeletal compartment in skeletal muscle results in muscular dystrophy.', Journal of Cell Biology, vol. 166, pp. 685 - 696, http://dx.doi.org/10.1083/jcb.200406181
Hook J; Lemckert F; Qin H; Schevzov G; Gunning P, 2004, 'Gamma tropomyosin gene products are required for embryonic development', Molecular and Cellular Biology, vol. 24, pp. 2318 - 2323, http://dx.doi.org/10.1128/MCB.24.6.2318-2323.2004
Percival JM; Hughes JA; Brown DL; Schevzov G; Heimann K; Vrhovski B; Bryce N; Stow JL; Gunning PW, 2004, 'Targeting of a tropomyosin isoform to short microfilaments associated with the Golgi complex', Mol Biol Cell, vol. 15, pp. 268 - 280, http://dx.doi.org/10.1091/mbc.E03-03-0176
Dalby-Payne JR; O'Loughlin EV; Gunning P, 2003, 'Polarization of Specific Tropomyosin Isoforms in Gastrointestinal Epithelial Cells and Their Impact on CFTR at the Apical Surface', Molecular Biology of the Cell, vol. 14, pp. 4365 - 4375, http://dx.doi.org/10.1091/mbc.E03-03-0169
Vrhovski B; Schevzov G; Dingle S; Lessard J; Gunning P; Weinberger R, 2003, 'Tropomyosin isoforms from the gamma gene differing at the C-terminus are spatially and developmentally regulated in the brain.', Journal of Neuroscience, vol. 72, pp. 373 - 383, http://dx.doi.org/10.1002/jnr.10586
Hughes J; Cooke-yarborough C; Chadwick N; Schevzov G; Arbuckle S; Gunning P; Weinberger R, 2003, 'High-molecular-weight tropomyosins localize to the contractile rings of dividing CNS cells but are absent from malignant paediatric and adult CNS tumors.', Glia, vol. 42, pp. 25 - 35, http://dx.doi.org/10.1002/glia.10174
Bryce N; Schevzov G; Ferguson V; Percival J; Lin JJ; Matsumura F; Bamburg J; Jeffrey P; Hardeman E; Gunning P; Weinberger R, 2003, 'Specification of actin filament function and molecular composition by tropomyosin isoforms.', Molecular Biology of the Cell, vol. 14, pp. 1002 - 1016, http://dx.doi.org/10.1091/mbc.E02-04-0244
Tay ES; Guven KL; Subramaniam N; Polly P; Issa LL; Gunning PW; Hardeman EC, 2003, 'Regulation of alternative splicing of Gtf2ird1 and its impact on slow muscle promoter activity', Biochemical Journal, vol. 374, pp. 359 - 367, http://dx.doi.org/10.1042/BJ20030189
Yager M; Thoms J; Lovicu F; Gunning P; Weinberger R; O'Neill G, 2003, 'Functional analysis of the actin-binding protein, tropomyosin 1, in neuroblastoma.', British Journal of Cancer, vol. 89, pp. 860 - 863, http://dx.doi.org/10.1038/sj.bjc.6601201
Durling HJ; Reilich P; Müller-Höcker J; Mendel B; Pongratz D; Wallgren-Pettersson C; Gunning P; Lochmüller H; Laing NG, 2002, 'De novo missense mutation in a constitutively expressed exon of the slow alpha-tropomyosin gene TPM3 associated with an atypical, sporadic case of nemaline myopathy', Neuromuscular Disorders, vol. 12, pp. 947 - 951, http://dx.doi.org/10.1016/S0960-8966(02)00182-7
Xiang H; Schevzov G; Gunning P; Williams HM; Silink M, 2002, 'A comparative study of growth-inhibitory effects of isoflavones and their metabolites on human breast and prostate cancer cell lines', Nutrition and Cancer, vol. 42, pp. 224 - 232, http://dx.doi.org/10.1207/S15327914NC422_12
Lloyd C; Gunning P, 2002, 'β- and γ-actin genes differ in their mechanisms of down-regulation during myogenesis', Journal of Cellular Biochemistry, vol. 84, pp. 335 - 342, http://dx.doi.org/10.1002/jcb.10014
Barbaric D; Dalla-Pozza L; Gunning P; Byrne JA, 2001, 'Differential expression of individual D52-like genes in childhood acute leukaemia.', BLOOD, vol. 98, pp. 185B - 185B, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000172134200843&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Gunning P; Ferguson V; Brennan KJ; Hardeman EC, 2001, 'Alpha-skeletal actin induces a subset of muscle genes independently of muscle differentiation and withdrawal from the cell cycle', Journal of Cell Science, vol. 114, pp. 513 - 524
Corbett MA; Robinson CS; Yang N; Joya JE; Stewart AW; Schnell C; Gunning PW; North KN; Hardeman E, 2001, 'A mutation in alpha-tropomyosin(slow) affects muscle strength, maturation and hypertrophy in a mouse model for nemaline myopathy', Human Molecular Genetics, vol. 10, pp. 317 - 328
Ilkovski B; Cooper ST; Nowak K; Ryan MM; Yang N; Schnell C; Durling HJ; Roddick LG; Wilkinson I; Kornberg AJ; Collins KJ; Wallace G; Gunning PW; Hardeman E; North K, 2001, 'Nemaline myopathy caused by mutations in the muscle alpha-skeletal-actin gene', American Journal of Human Genetics, vol. 68, pp. 1333 - 1343, http://dx.doi.org/10.1086/320605
Li Z; Elliott E; Gunning P; O'Loughlin E, 2001, 'DOES THE CYTOSKELETON OF INTESTINAL EPITHHELIAL CELLS FUNCTION AS A CELLULAR ALARM TO IDENTIFY THEE. COLIINFECTION', Journal of Gastroenterology and Hepatology, vol. 16, pp. 33 - 33, http://dx.doi.org/10.1111/j.1440-1746.2001.ca01-33.x
Percival JM; Weinberger RP; Stow JL; Gunning PW, 2000, 'Two gamma-tropomyosin isoforms are targeted to actin microfilaments associated with the Golgi complex', MOLECULAR BIOLOGY OF THE CELL, vol. 11, pp. 99A - 99A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000165525900518&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Xiang H; Schevzov G; Gunning PW; Williams HM; Silink M, 2000, 'The effects of genistein and two novel metabolites of isoflavones on antiproliferation, cell cycle and apoptosis in human breast and prostate cancer cell lines', MOLECULAR BIOLOGY OF THE CELL, vol. 11, pp. 448A - 448A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000165525902331&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Percival JM; Thomas G; Cock TA; Gardiner EM; Jeffrey PL; Lin JJC; Weinberger RP; Gunning P, 2000, 'Sorting of tropomyosin isoforms in synchronised NIH 3T3 fibroblasts: Evidence for distinct microfilament populations', Cell Motility and the Cytoskeleton, vol. 47, pp. 189 - 208, http://dx.doi.org/10.1002/1097-0169(200011)47:3<189::AID-CM3>3.0.CO;2-C
Weinberger R; Gunning P; Schevzov G, 2000, 'Staying in shape', Today's Life Science, vol. 12, pp. 14 - 19
Heimann K; Percival JM; Weinberger R; Gunning P; Stow JL, 1999, 'Specific isoforms of actin-binding proteins on distinct populations of Golgi-derived vesicles', Journal of Biological Chemistry, vol. 274, pp. 10743 - 10750, http://dx.doi.org/10.1074/jbc.274.16.10743
Li Z; Elliott E; Payne J; Isaacs J; Gunning P; O'Loughlin EV, 1999, 'Shiga toxin-producing Escherichia coli can impair T84 cell structure and function without inducing attaching/effacing lesions', Infection and Immunity, vol. 67, pp. 5938 - 5945, http://dx.doi.org/10.1128/iai.67.11.5938-5945.1999
Nourse CR; Mattei MG; Gunning P; Byrne JA, 1998, 'Cloning of a third member of the D52 gene family indicates alternative coding sequence usage in D52-like transcripts', Biochimica et Biophysica Acta - Gene Structure and Expression, vol. 1443, pp. 155 - 168, http://dx.doi.org/10.1016/S0167-4781(98)00211-5
Dufour C; Weinberger RP; Gunning P, 1998, 'Tropomyosin isoform diversity and neuronal morphogenesis', Immunology and Cell Biology, vol. 76, pp. 424 - 429, http://dx.doi.org/10.1046/j.1440-1711.1998.00765.x
Ferguson V; Tolhurst O; Jeffrey P; Gunning P; Weinberger R, 1998, 'Isoform specific effects of tropomyosins in neuronal differentiation.', MOLECULAR BIOLOGY OF THE CELL, vol. 9, pp. 135A - 135A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000076906700780&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Byrne JA; Mattei MG; Basset P; Gunning P, 1998, 'Identification and in situ hybridization mapping of a mouse Tpd52/1(D53) orthologue to chromosome 10A4-B2', Cytogenetics and Cell Genetics, vol. 81, pp. 199 - 201
Dufour C; Weinberger RP; Schevzov G; Jeffrey PL; Gunning P, 1998, 'Splicing of two internal and four carboxyl-terminal alternative exons in nonmuscle tropomyosin 5 pre-mRNA is independently regulated during development', Journal of Biological Chemistry, vol. 273, pp. 18547 - 18555, http://dx.doi.org/10.1074/jbc.273.29.18547
Byrne JA; Nourse CR; Basset P; Gunning P, 1998, 'Identification of homo- and heteromeric interactions between members of the breast carcinoma-associated D52 protein family using the yeast two-hybrid system', Oncogene, vol. 16, pp. 873 - 881, http://dx.doi.org/10.1038/sj.onc.1201604
Hannan AJ; Gunning P; Jeffrey PL; Weinberger RP, 1998, 'Structural compartments within neurons: Developmentally regulated organization of microfilament isoform mRNA and protein', Molecular and Cellular Neurosciences, vol. 11, pp. 289 - 304, http://dx.doi.org/10.1006/mcne.1998.0693
Gunning P; Weinberger R; Jeffrey P; Hardeman E, 1998, 'Isoform sorting and the creation of intracellular compartments', Annual Review of Cell and Developmental Biology, vol. 14, pp. 339 - 372, http://dx.doi.org/10.1146/annurev.cellbio.14.1.339
Gunning P; Hardeman E; Jeffrey P; Weinberger R, 1998, 'Creating intracellular structural domains: spatial segregation of actin and tropomyosin isoforms in neurons', BioEssays, vol. 20, pp. 892 - 900, http://dx.doi.org/10.1002/(SICI)1521-1878(199811)20:11<892::AID-BIES4>3.0.CO;2-D
Qin H; Gunning P, 1997, 'The 3'-end of the human β-actin gene enhances activity of the β-actin expression vector system: Construction of improved vectors', Journal of Biochemical and Biophysical Methods, vol. 36, pp. 63 - 72, http://dx.doi.org/10.1016/S0165-022X(97)00045-6
Weinberger R; Mcancy J; Cooke-Yarborough C; Arbuckle S; Kellie S; Jeffery P; Gunning P, 1997, 'High molecular weight tropomyosins: Potential markers for neoplasias of the CNS', BRAIN PATHOLOGY, vol. 7, pp. 1186 - 1186, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=A1997XQ52700247&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Gunning P; Weinberger R; Jeffrey P, 1997, 'Actin and tropomyosin isoforms in morphogenesis', Anatomy and Embryology, vol. 195, pp. 311 - 315, http://dx.doi.org/10.1007/s004290050050
Minamide LS; Painter WB; Schevzov G; Gunning P; Bamburg JR, 1997, 'Differential regulation of actin depolymerizing factor and cofilin in response to alterations in the actin monomer pool', Journal of Biological Chemistry, vol. 272, pp. 8303 - 8309, http://dx.doi.org/10.1074/jbc.272.13.8303
Schevzov G; Gunning P; Jeffrey PL; Temm-Grove C; Helfman DM; Lin JJC; Weinberger RP, 1997, 'Tropomyosin localization reveals distinct populations of microfilaments in neurites and growth cones', Molecular and Cellular Neurosciences, vol. 8, pp. 439 - 454, http://dx.doi.org/10.1006/mcne.1997.0599
Coumans JV; Yeoh T; Seeto RK; Keogh A; Brennan K; Gunning P; Hardeman E; Dos Remedios CG, 1997, 'Variations in relative mRNA levels of actin and myosin heavy chains do not produce corresponding differences in their proteins in the adult human heart', Journal of Molecular and Cellular Cardiology, vol. 29, pp. 895 - 905, http://dx.doi.org/10.1006/jmcc.1996.0317
Gunning P; Ferguson V; Brennan K; Hardeman E, 1997, 'Impact of α-Skeletal Actin but not α-Cardiac Actin on Myoblast Morphology', Cell Structure and Function, vol. 22, pp. 173 - 179, http://dx.doi.org/10.1247/csf.22.173
Minamide LS; Painter WB; Schevzov G; Gunning P; Bamburg JR, 1996, 'Expression of actin depolymerizing factor is responsive to the actin monomer pool', MOLECULAR BIOLOGY OF THE CELL, vol. 7, pp. 1177 - 1177, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996WB01801178&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Weinberger R; Schevzov G; Jeffrey P; Gordon K; Hill MA; Gunning P, 1996, 'The molecular composition of neuronal microfilaments is spatially and temporally regulated', Journal of Neuroscience, vol. 16, pp. 238 - 252
Schevzov G; Lloyd C; Gunning P, 1995, 'Impact of Altered Actin Gene Expression on Vinculin, Talin, Cell Spreading, and Motility', DNA and Cell Biology, vol. 14, pp. 689 - 700, http://dx.doi.org/10.1089/dna.1995.14.689
Hannan AJ; Schevzov G; Gunning P; Jeffrey PL; Weinberger RP, 1995, 'Intracellular localization of tropomyosin mRNA and protein is associated with development of neuronal polarity', Molecular and Cellular Neurosciences, vol. 6, pp. 397 - 412, http://dx.doi.org/10.1006/mcne.1995.1030
Silva RD; Englezou A; Schevzov G; Gerwin BI; Harris CC; Gunning P; Reddel RR, 1994, 'Induction of anchorage independent growth and serum resistance in immortalized human bronchial epithelial cells by alteration of the cytoskeleton', Cellular and Molecular Biology Research, vol. 40, pp. 323 - 335
Hailstones D; Gunning P, 1994, 'Regulation of nonmuscle myosin light chain 3 gene expression in response to exogenous MLC3nm mRNA', Cellular and Molecular Biology Research, vol. 40, pp. 53 - 62
Hill MA; Schedlich L; Gunning P, 1994, 'Serum-induced signal transduction determines the peripheral location of β-actin mRNA within the cell', Journal of Cell Biology, vol. 126, pp. 1221 - 1230, http://dx.doi.org/10.1083/jcb.126.5.1221
Esser K; Gunning P; Hardeman E, 1993, 'Nerve-dependent and -independent patterns of mRNA expression in regenerating skeletal muscle', Developmental Biology, vol. 159, pp. 173 - 183, http://dx.doi.org/10.1006/dbio.1993.1231
Trahair T; Yeoh T; Cartmill T; Keogh A; Spratt P; Chang V; dos Remedios CG; Gunning P, 1993, 'Myosin Light Chain Gene Expression Associated with Disease States of the Human Heart', Journal of Molecular and Cellular Cardiology, vol. 25, pp. 577 - 585, http://dx.doi.org/10.1006/jmcc.1993.1067
Schevzov G; Lloyd C; Hailstones D; Gunning P, 1993, 'Differential regulation of tropomyosin isoform organization and gene expression in response to altered actin gene expression', Journal of Cell Biology, vol. 121, pp. 811 - 821, http://dx.doi.org/10.1083/jcb.121.4.811
Weinberger RP; Henke RC; Tolhurst O; Jeffrey PL; Gunning P, 1993, 'Induction of neuron-specific tropomyosin mRNAs by nerve growth factor is dependent on morphological differentiation', Journal of Cell Biology, vol. 120, pp. 205 - 215, http://dx.doi.org/10.1083/jcb.120.1.205
Lloyd C; Gunning P, 1993, 'Noncoding regions of the γ-actin gene influence the impact of the gene on myoblast morphology', Journal of Cell Biology, vol. 121, pp. 73 - 82, http://dx.doi.org/10.1083/jcb.121.1.73
Hill MA; Gunning P, 1993, 'Beta and gamma actin mRNAs are differentially located within myoblasts', Journal of Cell Biology, vol. 122, pp. 825 - 832, http://dx.doi.org/10.1083/jcb.122.4.825
WEINBERGER RP; HENKE RC; TOLHURST O; JEFFREY PL; GUNNING P, 1992, 'INDUCTION OF NEURONAL TROPOMYOSINS BY NGF IS DEPENDENT ON MORPHOLOGICAL-DIFFERENTIATION', MOLECULAR BIOLOGY OF THE CELL, vol. 3, pp. A40 - A40, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1992JR25500230&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Lloyd C; Schevzov G; Gunning P, 1992, 'Transfection of nonmuscle β- and γ-actin genes into myoblasts elicits different feedback regulatory responses from endogenous actin genes', Journal of Cell Biology, vol. 117, pp. 787 - 797, http://dx.doi.org/10.1083/jcb.117.4.787
Schevzov G; Lloyd C; Gunning P, 1992, 'High level expression of transfected β- and γ-actin genes differentially impacts on myoblast cytoarchitecture', Journal of Cell Biology, vol. 117, pp. 775 - 785, http://dx.doi.org/10.1083/jcb.117.4.775
Dowsing BJ; Gooley AA; Gunning P; Cunningham A; Jeffrey PL, 1992, 'Molecular cloning and primary structure of the avian Thy-1 glycoprotein', Molecular Brain Research, vol. 14, pp. 250 - 260, http://dx.doi.org/10.1016/0169-328X(92)90180-J
Hailstones D; Barton P; Chan-Thomas P; Sasse S; Sutherland C; Hardeman E; Gunning P, 1992, 'Differential regulation of the atrial isoforms of the myosin light chains during striated muscle development', Journal of Biological Chemistry, vol. 267, pp. 23295 - 23300
Henke RC; Tolhurst O; Sentry JW; Gunning P; Jeffrey PL, 1991, 'Expression of actin and myosin genes during PC12 cell differentiation', Neurochemical Research, vol. 16, pp. 675 - 679, http://dx.doi.org/10.1007/BF00965554
Gunning P; Hardeman E, 1991, 'Multiple mechanisms regulate muscle fiber diversity', The FASEB Journal, vol. 5, pp. 3064 - 3071
Gunning P; Gordon M; Wade R; Gahlmann R; Lin CS; Hardeman E, 1990, 'Differential control of tropomyosin mRNA levels during myogenesis suggests the existence of an isoform competition-autoregulatory compensation control mechanism', Developmental Biology, vol. 138, pp. 443 - 453, http://dx.doi.org/10.1016/0012-1606(90)90210-A
Wade R; Sutherland C; Gahlmann R; Kedes L; Hardeman E; Gunning P, 1990, 'Regulation of contractile protein gene family mRNA pool sizes during myogenesis', Developmental Biology, vol. 142, pp. 270 - 282, http://dx.doi.org/10.1016/0012-1606(90)90348-M
Webster KA; Gunning P; Hardeman E; Wallace DC; Kedes L, 1990, 'Coordinate reciprocal trends in glycolytic and mitochondrial transcript accumulations during the in vitro differentiation of human myoblasts', Journal of Cellular Physiology, vol. 142, pp. 566 - 573, http://dx.doi.org/10.1002/jcp.1041420316
Hailstones DL; Gunning PW, 1990, 'Characterization of human myosin light chains 1sa and 3nm: Implications for isoform evolution and function', Molecular and Cellular Biology, vol. 10, pp. 1095 - 1104, http://dx.doi.org/10.1128/MCB.10.3.1095
Wade R; Feldman D; Gunning P; Kedes L, 1989, 'Sequence and expression of human myosin alkali light chain isoforms', Molecular and Cellular Biochemistry, vol. 87, pp. 119 - 136, http://dx.doi.org/10.1007/BF00219255
Ng SY; Gunning P; Liu SH; Leavitt J; Kedes L, 1989, 'Regulation of the human β-actin promoter by upstream and intron domains', Nucleic Acids Research, vol. 17, pp. 601 - 615, http://dx.doi.org/10.1093/nar/17.2.601
Gahlmann R; Wade R; Gunning P; Kedes L, 1988, 'Differential expression of slow and fast skeletal muscle troponin C. Slow skeletal muscle troponin C is expressed in human fibroblasts', Journal of Molecular Biology, vol. 201, pp. 379 - 391, http://dx.doi.org/10.1016/0022-2836(88)90145-3
Erba HP; Eddy R; Shows T; Kedes L; Gunning P, 1988, 'Structure, chromosome location, and expression of the human γ-actin gene: Differential evolution, location, and expression of the cytoskeletal β- and γ-actin genes', Molecular and Cellular Biology, vol. 8, pp. 1775 - 1789, http://dx.doi.org/10.1128/MCB.8.4.1775
Gahlmann R; Troutt AB; Wade RP; Gunning P; Kedes L, 1987, 'Alternative splicing generates variants in important functional domains of human slow skeletal troponin T', Journal of Biological Chemistry, vol. 262, pp. 16122 - 16126
Gunning P; Leavitt J; Muscat G; Kedes L, 1987, 'A human β-actin expression vector system directs high-level accumulation of antisense transcripts', Proceedings of the National Academy of Sciences of the United States of America, vol. 84, pp. 4831 - 4835, http://dx.doi.org/10.1073/pnas.84.14.4831
Gunning P; Hardeman E; Wade R; Ponte P; Bains W; Blau HM; Kedes L, 1987, 'Differential patterns of transcript accumulation during human myogenesis.', Molecular and cellular biology, vol. 7, pp. 4100 - 4114, http://dx.doi.org/10.1128/MCB.7.11.4100
WADE R; GUNNING P; HARDEMAN E; GAHLMANN R; BLAU H; KEDES L, 1987, 'DISTINCTIVE PATTERNS OF MUSCLE-SPECIFIC MESSENGER-RNA ACCUMULATION DURING HUMAN MYOGENESIS', JOURNAL OF CELLULAR BIOCHEMISTRY, pp. 96 - 96, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1987G822600243&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
TAYLOR A; GUNNING P; KEDES L, 1987, 'RNA EXPRESSION PATTERNS IN THE RAT L8 MYOGENIC CELL-LINE', JOURNAL OF CELLULAR BIOCHEMISTRY, pp. 160 - 160, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1987G822600437&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
NG SY; GUNNING P; KEDES L; LEAVITT J, 1987, 'GROWTH-REGULATION OF THE HUMAN BETA-ACTIN GENE PROMOTER', JOURNAL OF CELLULAR BIOCHEMISTRY, pp. 64 - 64, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1987G108200167&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
GAHLMANN R; TROUTT AB; WADE RP; GUNNING P; KEDES L, 1987, 'A NOVEL SCHEME OF ALTERNATIVE SPLICING IN THE TROPONIN-T FAMILY REVEALED BY THE CLONING AND SEQUENCING OF 2 DIFFERENT HUMAN SLOW ISOFORM CDNAS', JOURNAL OF CELLULAR BIOCHEMISTRY, pp. 123 - 123, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1987G822600325&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Leavitt J; Ng SY; Aebi U; Varma M; Latter G; Burbeck S; Kedes L; Gunning P, 1987, 'Expression of transfected mutant beta-actin genes: alterations of cell morphology and evidence for autoregulation in actin pools.', Molecular and cellular biology, vol. 7, pp. 2457 - 2466, http://dx.doi.org/10.1128/MCB.7.7.2457
Leavitt J; Ng SY; Varma M; Latter G; Burbeck S; Gunning P; Kedes L, 1987, 'Expression of transfected mutant beta-actin genes: transitions toward the stable tumorigenic state.', Molecular and cellular biology, vol. 7, pp. 2467 - 2476, http://dx.doi.org/10.1128/MCB.7.7.2467
Erba HP; Gunning P; Kedes L, 1986, 'Nucleotide sequence of the human γ cytoskeletal actin mRNA: Anomalous evolution of vertebrate non-muscle actin genes', Nucleic Acids Research, vol. 14, pp. 5275 - 5294, http://dx.doi.org/10.1093/nar/14.13.5275
Wade R; Gunning P; Eddy R; Shows T; Kedes L, 1986, 'Nucleotide sequence, tissue-specific expression, and chromosome location of human carbonic anhydrase III: The human CAIII gene is located on the same chromosome as the closely linked CAI and CAII genes', Proceedings of the National Academy of Sciences of the United States of America, vol. 83, pp. 9571 - 9575, http://dx.doi.org/10.1073/pnas.83.24.9571
KEDES L; MINTY A; WADE R; GUNNING P; HARDEMAN E; BLAU H; BENTONVOSMAN P; BOXER L; ERBA H; FELDMAN D; GAHLMANN R; MIWA T; MUSCAT G; TAYLOR A, 1986, 'MULTILEVEL REGULATION OF GENE-EXPRESSION IN HUMAN MYOGENESIS - DISSOCIATION OF FACTORS RESPONSIBLE FOR MODULATION AND ACTIVATION AND EVIDENCE FOR NON-COORDINATE EXPRESSION', JOURNAL OF CELLULAR BIOCHEMISTRY, pp. 16 - 16, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1986A664400029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hickey R; Skoultchi A; Gunning P; Kedes L, 1986, 'Regulation of a human cardiac actin gene introduced into rat L6 myoblasts suggests a defect in their myogenic program.', Molecular and cellular biology, vol. 6, pp. 3287 - 3290, http://dx.doi.org/10.1128/MCB.6.9.3287
Kedes L; Ng SY; Lin CS; Gunning P; Eddy R; Shows T; Leavitt J, 1985, 'The human beta-actin multigene family.', Transactions of the Association of American Physicians, vol. 98, pp. 42 - 46
Lin CS; Ng SY; Gunning P; Kedes L; Leavitt J, 1985, 'Identification and order of sequential mutations in β-actin genes isolated from increasingly tumorigenic human fibroblast strains', Proceedings of the National Academy of Sciences of the United States of America, vol. 82, pp. 6995 - 6999, http://dx.doi.org/10.1073/pnas.82.20.6995
Leavitt J; Gunning P; Kedes L; Jariwalla R, 1985, 'Smooth muscle α-actin is a transformation-sensitive marker for mouse NIH 3T3 and Rat-2 cells', Nature, vol. 316, pp. 840 - 842, http://dx.doi.org/10.1038/316840a0
Ng SY; Gunning P; Eddy R; Ponte P; Leavitt J; Shows T; Kedes L, 1985, 'Evolution of the functional human β-actin gene and its multi-pseudogene family: conservation of noncoding regions and chromosomal dispersion of pseudogenes', Molecular and Cellular Biology, vol. 5, pp. 2720 - 2732, http://dx.doi.org/10.1128/mcb.5.10.2720
Garrison JC; Hardeman E; Wade R; Kedes L; Gunning P, 1985, 'Isolation of full-length cDNAs encoding abundant adult human skeletal muscle mRNAs', Gene, vol. 38, pp. 177 - 188, http://dx.doi.org/10.1016/0378-1119(85)90216-1
NG SY; GUNNING P; EDDY R; PONTE P; LEAVITT J; KEDES L; SHOWS T, 1985, 'CHROMOSOME-7 ASSIGNMENT OF THE HUMAN BETA-ACTIN FUNCTIONAL GENE (ACTB) AND THE CHROMOSOMAL DISPERSION OF PSEUDOGENES', CYTOGENETICS AND CELL GENETICS, vol. 40, pp. 712 - 712, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1985AVS2100298&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Gunning P; Mohun T; Ng SY; Ponte P; Kedes L, 1984, 'Evolution of the human sarcomeric-actin genes: Evidence for units of selection within the 3′ untranslated regions of the mRNAs', Journal of Molecular Evolution, vol. 20, pp. 202 - 214, http://dx.doi.org/10.1007/BF02104727
Ponte P; Ng SY; Engel J; Gunning P; Kedes L, 1984, 'Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA', Nucleic Acids Research, vol. 12, pp. 1687 - 1696, http://dx.doi.org/10.1093/nar/12.3.1687
Scheffer JW; Howe N; Gunning PW; Austin L, 1984, 'Axoplasmic Transport of Transfer RNA in the Chick Optic System', Journal of Neurochemistry, vol. 42, pp. 698 - 704, http://dx.doi.org/10.1111/j.1471-4159.1984.tb02739.x
Gunning P; Ponte P; Kedes L; Hickey RJ; Skoultchi AI, 1984, 'Expression of human cardiac actin in mouse L cells: A sarcomeric actin associates with a nonmuscle cytoskeleton', Cell, vol. 36, pp. 709 - 715, http://dx.doi.org/10.1016/0092-8674(84)90351-9
SHOWS T; EDDY RL; HALEY L; BYERS M; HENRY M; GUNNING P; PONTE P; KEDES L, 1984, 'THE COEXPRESSED GENES FOR HUMAN ALPHA (ACTA) AND CARDIAC ACTIN (ACTC) ARE ON CHROMOSOME-1 AND CHROMOSOME-15, RESPECTIVELY', CYTOGENETICS AND CELL GENETICS, vol. 37, pp. 583 - 583, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1984RV30800269&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
CHIU CP; HARDEMAN EC; GUNNING P; BLAU HM, 1984, 'TRANSCRIPTIONAL ACTIVATION OF SARCOMERIC ACTINS IN MUSCLE X NONMUSCLE HETEROKARYONS', JOURNAL OF CELL BIOLOGY, vol. 99, pp. A346 - A346, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1984TM94901278&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Leavitt J; Gunning P; Porreca P; Lin CS; Kedes L, 1984, 'Molecular cloning and characterization of mutant and wild-type human β-actin genes', Molecular and Cellular Biology, vol. 4, pp. 1961 - 1969, http://dx.doi.org/10.1128/MCB.4.10.1961
Gunning P; Ponte P; Kedes L; Eddy R; Shows T, 1984, 'Chromosomal location of the co-expressed human skeletal and cardiac actin genes', Proceedings of the National Academy of Sciences of the United States of America, vol. 81, pp. 1813 - 1817, http://dx.doi.org/10.1073/pnas.81.6.1813
Young AP; Gunning PW; Landreth GE; Ignatius M; Shooter EM, 1983, 'The nerve growth factor induced differentiation of a pheochromocytoma PC12 cell line', Birth Defects: Original Article Series, vol. 19, pp. 33 - 46
Ponte P; Gunning P; Blau H; Kedes L, 1983, 'Human actin genes are single copy for α-skeletal and α-cardiac actin but multicopy for β- and γ-cytoskeletal genes: 3' Untranslated regions are isotype specific but are conserved in evolution', Molecular and Cellular Biology, vol. 3, pp. 1783 - 1791, http://dx.doi.org/10.1128/mcb.3.10.1783
Gunning P; Ponte P; Blau H; Kedes L, 1983, 'α-Skeletal and α-cardiac actin genes are coexpressed in adult human skeletal muscle and heart', Molecular and Cellular Biology, vol. 3, pp. 1985 - 1995, http://dx.doi.org/10.1128/mcb.3.11.1985
Gunning P; Ponte P; Okayama H; Engel J; Blau H; Kedes L, 1983, 'Isolation and characterization of full-length cDNA clones for human α, β, and γ-actin mRNAs: Skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed', Molecular and Cellular Biology, vol. 3, pp. 787 - 795, http://dx.doi.org/10.1128/MCB.3.5.787
PONTE P; GUNNING P; ENGEL J; BLAU H; KEDES L, 1983, 'MESSENGER-RNAS FOR THE SINGLE COPY HUMAN SARCOMERIC ALPHA-ACTIN AND CARDIAC-ACTIN GENES, AND FOR THE MULTIPLE COPY CYTOSKELETAL BETA-ACTIN AND GAMMA-ACTIN GENES - 3' - UNTRANSLATED REGIONS ARE NONHOMOLOGOUS BUT ARE CONSERVED IN EVOLUTION', FEDERATION PROCEEDINGS, vol. 42, pp. 2116 - 2116, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1983QM89402107&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Kedes DH; Gunning PW; Shooter EM, 1982, 'Nerve growth factor‐induced stimulation of α‐aminoisobutyric acid uptake in PC12 cells: Relationship to plasma membrane receptor occupancy', Journal of Neuroscience Research, vol. 8, pp. 357 - 365, http://dx.doi.org/10.1002/jnr.490080224
Engel J; Gunning P; Kedes L, 1982, 'Human cytoplasmic actin proteins are encoded by a multigene family', Molecular and Cellular Biology, vol. 2, pp. 674 - 684, http://dx.doi.org/10.1128/MCB.2.6.674
Kedes DH; Gunning PW; Shooter EM, 1982, 'Nerve growth factor‐induced stimulation of α‐aminoisobutyric acid uptake in PC 12 cells: Evaluation of its biological significance', Journal of Neuroscience Research, vol. 8, pp. 367 - 374, http://dx.doi.org/10.1002/jnr.490080225
Gunning PW; Béguin P; Shooter EM; Austin L; Jeffrey PL, 1981, 'Characterization of the association of two small molecular weight RNAs with eukaryotic polysomes.', Journal of Biological Chemistry, vol. 256, pp. 6670 - 6675
Gunning PW; Shooter EM; Austin L; Jeffrey PL, 1981, 'Differential and coordinate regulation of the eukaryotic small molecular weight RNAs.', Journal of Biological Chemistry, vol. 256, pp. 6663 - 6669
Engel JN; Gunning PW; Kedes L, 1981, 'Isolation and characterization of human actin genes', Proceedings of the National Academy of Sciences of the United States of America, vol. 78, pp. 4674 - 4678, http://dx.doi.org/10.1073/pnas.78.8.4674
Gunning PW; Letourneau PC; Landreth GE; Shooter EM, 1981, 'The action of nerve growth factor and dibutyryl adenosine cyclic 3':5'-monophosphate on rat pheochromocytoma reveals distinct stages in the mechanisms underlying neurite outgrowth', Journal of Neuroscience, vol. 1, pp. 1085 - 1095, http://dx.doi.org/10.1523/jneurosci.01-10-01085.1981
Gunning PW; Landreth GE; Layer P; Ignatius M; Shooter EM, 1981, 'Nerve growth factor-induced differentiation of PC12 cells: Evaluation of changes in RNA and DNA metabolism', Journal of Neuroscience, vol. 1, pp. 368 - 379, http://dx.doi.org/10.1523/jneurosci.01-04-00368.1981
Gunning PW; Landreth GE; Bothwell MA; Shooter EM, 1981, 'Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells', Journal of Cell Biology, vol. 89, pp. 240 - 245, http://dx.doi.org/10.1083/jcb.89.2.240
Gunning PW; Por SB; Langford CJ; Scheffer J; Austin L; Jeffrey PL, 1979, 'THE DIRECT MEASUREMENT OF THE AXOPLASMIC TRANSPORT OF INDIVIDUAL RNA SPECIES: TRANSFER BUT NOT RIBOSOMAL RNA IS TRANSPORTED', Journal of Neurochemistry, vol. 32, pp. 1737 - 1743, http://dx.doi.org/10.1111/j.1471-4159.1979.tb02286.x
Gunning PW; Austin L; Jeffrey PL, 1979, 'THE TURNOVER AND SUBCELLULAR LOCALIZATION OF THE CHICK FOREBRAIN SMALL NUCLEAR RNAs', Journal of Neurochemistry, vol. 32, pp. 1725 - 1736, http://dx.doi.org/10.1111/j.1471-4159.1979.tb02285.x
Por S; Gunning PW; Jeffrey PL; Austin L, 1978, 'Axonal transport of 4S RNA in the chick optic system', Neurochemical Research, vol. 3, pp. 411 - 422, http://dx.doi.org/10.1007/BF00966323
Por SB; Komiya Y; McGregor A; Jeffrey PL; Gunning PW; Austin L, 1978, 'The axoplasmic transport of 4S RNA within the sciatic nerve of the chicken', Neuroscience Letters, vol. 8, pp. 165 - 169, http://dx.doi.org/10.1016/0304-3940(78)90191-X
Langford CJ; Kaye PL; Austin L; Gunning PW, 1977, 'The in vivo synthesis of stable RNA within the vagus nerve following vagotomy', Neuroscience Letters, vol. 6, pp. 15 - 19, http://dx.doi.org/10.1016/0304-3940(77)90058-1
Gunning PW; Kaye PL; Austin L, 1977, 'IN VIVO SYNTHESIS OF RAPIDLY‐LABELLED RNA WITHIN THE RAT NODOSE GANGLIA FOLLOWING VAGOTOMY', Journal of Neurochemistry, vol. 28, pp. 1245 - 1248, http://dx.doi.org/10.1111/j.1471-4159.1977.tb12317.x
Gunning PW; Kaye PL; Austin L, 1977, 'IN VIVO RNA SYNTHESIS WITHIN THE RAT NODOSE GANGLIA', Journal of Neurochemistry, vol. 28, pp. 1237 - 1240, http://dx.doi.org/10.1111/j.1471-4159.1977.tb12315.x
Kaye PL; Gunning PW; Austin L, 1977, 'IN VIVO SYNTHESIS OF STABLE RNA WITHIN THE RAT NODOSE GANGLIA FOLLOWING VAGOTOMY', Journal of Neurochemistry, vol. 28, pp. 1241 - 1243, http://dx.doi.org/10.1111/j.1471-4159.1977.tb12316.x
KAYE PL; GUNNING PW, 1976, 'SYNTHESIS OF RNA IN NODOSE GANGLIA FOLLOWING AXON INJURY', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, vol. 9, pp. 43 - 43, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1976DR08000107&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
GUNNING PW, 1976, 'SMALL MOLECULAR-WEIGHT RNAS - TOWARDS A BIOLOGICAL ROLE', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, vol. 9, pp. 42 - 42, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1976DR08000104&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Jeffrey PL; Austin L; Gunning PW, 1976, 'The RNA of chick forebrain synaptosomes', Neuroscience Letters, vol. 2, pp. 153 - 158, http://dx.doi.org/10.1016/0304-3940(76)90007-0
GUNNING PW; JEFFREY PL; AUSTIN L, 1975, 'HIGH AND LOW-MOLECULAR WEIGHT RNA IN SUBFRACTIONS OF CHICK BRAIN', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, vol. 8, pp. 86 - 86, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1975AM36400177&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Bryce NS; Failes TW; Stehn JR; Baker K; Zahler S; Arzhaeva Y; Bischof L; Lyons C; Dedova I; Arndt GM; Gaus K; Goult BT; Hardeman EC; Gunning PW; Lock JG, 'The Limits of Phenotypic Plasticity in the Actin Cytoskeleton Revealed by Unbiased Chemical Perturbation', SSRN Electronic Journal, http://dx.doi.org/10.2139/ssrn.3299445
Conference Papers
Xu X; Wang Y; Bryce N; Tang K; Meagher NS; Kang EY; Kelemen LE; Köbel M; Ramus SJ; Friedlander M; Ford CE; Hardeman EC; Gunning PW, 2021, 'Abstract 1045: Combined targeting of actin/tropomyosin and microtubules underlies a potential treatment strategy of epithelial ovarian cancer with cell-cycle dependent synergy', in Cancer Research, American Association for Cancer Research (AACR), pp. 1045 - 1045, presented at Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA, http://dx.doi.org/10.1158/1538-7445.am2021-1045
Xu X; Wang Y; Bryce N; Tang K; Meagher NS; Kang EY; Kelemen LE; Kobel M; Ramus SJ; Friedlander M; Ford CE; Hardeman EC; Gunning PW, 2021, 'Combined targeting of actin/tropomyosin and microtubules underlies a potential treatment strategy of epithelial ovarian cancer with cell-cycle dependent synergy.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000680263503257&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Gunning P; Wang Y; Stear JH; Swain A; Xu X; Bryce N; Alieva IB; Dugina VB; Cripe T; Stehn J; Hardeman EC, 2020, 'Anti-tropomyosin drugs prevent the rescue of vincristine-induced mitotic spindle defects', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-5817
Sao K; Jones TM; Doyle AD; Schevzov G; Gunning PW; Petrie RJ, 2018, 'Myosin II governs intracellular pressure and traction force by distinct tropomyosin-dependent mechanisms.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000505772703133&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Sao K; Jones TM; Doyle AD; Schevzov G; Gunning PW; Petrie RJ, 2017, 'Myosin II governs intracellular pressure and traction force by distinct mechanisms.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, presented at Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO), Philadelphia, PA, 02 December 2017 - 06 December 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426664300605&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Meiring J; Bryce NS; Hardeman EC; Gunning PW, 2016, 'Human cells contain enough tropomyosin to saturate all actin filaments', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, San Francisco, CA, presented at Annual Meeting of the American-Society-for-Cell-Biology (ASCB), San Francisco, CA, 03 December 2016 - 07 December 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000396046900904&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Jeong S; Lim S; Schevzov G; Gunning PW; Helfman DM, 2016, 'Down-regulation of a high molecular weight tropomyosin Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, San Francisco, CA, presented at Annual Meeting of the American-Society-for-Cell-Biology (ASCB), San Francisco, CA, 03 December 2016 - 07 December 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000396047200278&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Oldfield R; Jalilian I; Pereira A; Gunning P; Knothe Tate ML, 2015, 'Live Multiplexed Imaging and Modeling of Stem Cell Mechanomics', in Proceedings of the 2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI 2015), Institute of Electrical and Electronics Engineers ( IEEE ), presented at IEEE International Symposium on Biomedical Imaging, 16 April 2015 - 19 April 2015, http://www.ieee.org/conferences_events/conferences/conferencedetails/index.html?Conf_ID=21167
Obeidy P; Sobey TL; Pandzic E; Nicovich PR; Coster A; Gunning P; Boecking T, 2015, 'Actin tropomyosin assembly intermediates', in Actin tropomyosin assembly intermediates, Annual Biophysical Society Meeting, Baltimore (USA), pp. 298a - 298a, presented at Annual Biophysical Society Meeting, Baltimore (USA), 07 February 2015 - 11 February 2015, https://www.cell.com/biophysj/pdf/S0006-3495(14)02828-8.pdf
Kee AJ; Masedunskas A; Lucas CA; Han W; Gunning PW; Hardeman EC, 2015, 'Measuring GLUT4 vesicle exocytosis using intracellular intravital microscopy.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209928400023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Knothe Tate ML; Gunning P; Sansalone V, 2014, 'Mapping the Mechanome: Retrospective and Prospective Approaches', in Mapping the Mechanome: Retrospective and Prospective Approaches, 7th World Congress of Biomechanics, pp. 14-IS-5274-WCB, presented at 7th World Congress of Biomechanics, 06 July 2014 - 11 July 2014, http://www.esbiomech.org/?page_id=2437
Hardeman EC; Darhed HA; Lee ASJ; Chen G; Shah J; Joya JE; Gunning PW, 2012, 'BLOOD BORNE AGENTS RESCUE REGENERATION IMPAIRED MUSCLE', in WOUND REPAIR AND REGENERATION, WILEY-BLACKWELL, pp. A59 - A59, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308945000025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stehn JR; Haass NK; Bonello T; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PR; Butler T; Allanson M; Fath T; Hill TA; McCluskey A; Schevzov G; Palmer S; Hardeman EC; Winlaw D; Reeve VE; Dixon I; Weninger W; Cripe TP; Gunning P, 2012, 'Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells', in EXPERIMENTAL DERMATOLOGY, WILEY-BLACKWELL, Marburg, GERMANY, pp. e43 - e43, presented at 39th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Marburg, GERMANY, 01 March 2012 - 03 March 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000300931700252&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Kee AJ; Lucas CA; Yang L; Szokolai RC; Martel N; Leong GM; Muscat GE; Hughes W; Cooney G; James DE; Gunning PW; Hardeman EC, 2012, 'The actin regulatory protein Tropomyosin 5NM1 regulates glucose uptake and GLUT4 trafficking in the mouse.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348601218&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Bonello TT; Stehn J; Hitchcock-DeGregori S; Dixon I; Gunning P, 2011, 'Optimising models to examine the specificity of anti-tropomyosin compounds for Tm5NM1', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Denver, CO, presented at Annual Meeting of the American-Society-for-Cell-Biology (ASCB), Denver, CO, 03 December 2011 - 07 December 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000305505500216&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Kee A; Lucas C; Szokolai R; Yang L; Martel N; Leong G; Muscat G; Hughes W; James D; Gunning P; Hardeman E, 2011, 'A novel actin filament class that regulates glucose uptake and GLUT4 trafficking', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Denver, CO, presented at Annual Meeting of the American-Society-for-Cell-Biology (ASCB), Denver, CO, 03 December 2011 - 07 December 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000305505500204&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Curthoys N; Freittag H; Connor A; Desouza M; Hardeman E; Gunning P; Schevzov G; Fath T, 2011, 'Tropomyosins induce neurite formation in B35 neuroblastoma cells and control neurite branching', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Denver, CO, presented at Annual Meeting of the American-Society-for-Cell-Biology (ASCB), Denver, CO, 03 December 2011 - 07 December 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000305505503094&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stehn JR; Haass NK; Bonello T; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PRBB; Butler T; Hill TA; McCluskey A; Palmer S; Hardeman EC; Winlaw D; Weninger W; Cripe TP; Gunning P, 2011, 'Abstract A178: Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells.', in New Molecular Targets, American Association for Cancer Research, presented at Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Nov 12-16, 2011; San Francisco, CA, http://dx.doi.org/10.1158/1535-7163.targ-11-a178
Stehn J; Schevzov G; Bonello T; McCluskey A; Haass N; Palmer S; Hardeman E; Allanson M; Reeve V; Gunning P, 2010, 'Tropomyosin Tm5NM1: A novel target for cancer therapy', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, Berlin, GERMANY, pp. 107 - 107, presented at 22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Berlin, GERMANY, 16 November 2010 - 19 November 2010, http://dx.doi.org/10.1016/S1359-6349(10)72041-3
Morse A; Schindeler A; Kramer B; Alexander IE; Gunning P; Little DG, 2009, 'Selective bone marrow transplantation using low-dose chemotherapy', in BONE, ELSEVIER SCIENCE INC, Sydney, AUSTRALIA, pp. S125 - S125, presented at 2nd Joint Meeting of the International-Bone-and-Mineral-Society/Australian-New-Zealand-Bone-and-Mineral-Society, Sydney, AUSTRALIA, 21 March 2009 - 25 March 2009, http://dx.doi.org/10.1016/j.bone.2009.01.275
Hu M; Kramer B; Zhang GY; Wang YM; McCowage G; Alexander IE; Gunning P; Alexander SI, 2007, 'Skin allograft tolerance across a major MHC mismatch in mixed chimeric mice is associated with high foxp3 expression.', in AMERICAN JOURNAL OF TRANSPLANTATION, BLACKWELL PUBLISHING, San Francisco, CA, pp. 581 - 581, presented at Annual American Transplant Congress, San Francisco, CA, 05 May 2007 - 09 May 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000246370202551&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Williams A; Kramer B; Alexander IE; Gunning P; McCowage G, 2007, 'Optimisation studies for vector supernatant production prior to the initiation of a Phase I clinical trial', in JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Shine Dome Acad Sci, Canberra, AUSTRALIA, pp. 540 - 540, presented at 5th Meeting of the Australasian-Gene-Therapy-Society, Shine Dome Acad Sci, Canberra, AUSTRALIA, 18 April 2007 - 20 April 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000247756300063&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Singh R; Latham M; Kramer B; Williams A; Gunning P; Alexander I, 2007, 'Achieving GMP compliance for gene therapy clinical trial activities', in JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Shine Dome Acad Sci, Canberra, AUSTRALIA, pp. 539 - 539, presented at 5th Meeting of the Australasian-Gene-Therapy-Society, Shine Dome Acad Sci, Canberra, AUSTRALIA, 18 April 2007 - 20 April 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000247756300058&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Kramer BA; Alexander IE; Gunning PW; McCowage GB, 2007, 'A low intensity conditioning bone marrow transplant model based on MGMT gene transfer and in vivo selection', in JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Shine Dome Acad Sci, Canberra, AUSTRALIA, pp. 530 - 530, presented at 5th Meeting of the Australasian-Gene-Therapy-Society, Shine Dome Acad Sci, Canberra, AUSTRALIA, 18 April 2007 - 20 April 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000247756300030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hyman J; Ginn SL; Kramer BA; Gunning PW; Alexander IE, 2007, 'Establishment and validation of a LAM-PCR assay for retroviral integration site analysis during a clinical trial', in JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Shine Dome Acad Sci, Canberra, AUSTRALIA, pp. 536 - 536, presented at 5th Meeting of the Australasian-Gene-Therapy-Society, Shine Dome Acad Sci, Canberra, AUSTRALIA, 18 April 2007 - 20 April 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000247756300050&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Macarthur D; Yang N; Seto J; Raftery J; Kee A; Hardeman E; Gunning P; North K, 2006, 'A gene for speed: the ACTN3 R577X polymorphism influences muscle performance', in NEUROMUSCULAR DISORDERS, PERGAMON-ELSEVIER SCIENCE LTD, Istanbul, TURKEY, pp. S59 - S59, presented at 11th International Congress on Neuromuscular Diseases, Istanbul, TURKEY, 02 July 2006 - 07 July 2006, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000239229400042&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Domazetovska A; Ilkovski B; Cooper S; Valova V; Lemckert F; Hook J; Hardeman E; Robinson P; Yang N; Gunning P; North K, 2006, 'Unravelling the thin filament: mechanisms of weakness in inherited muscle disease', in NEUROMUSCULAR DISORDERS, PERGAMON-ELSEVIER SCIENCE LTD, Istanbul, TURKEY, pp. S60 - S61, presented at 11th International Congress on Neuromuscular Diseases, Istanbul, TURKEY, 02 July 2006 - 07 July 2006, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000239229400046&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Yang N; MacArthur DG; Kee AJ; Kettle E; Hardeman EC; Lemckert F; Hook J; Gunning PW; North KN, 2006, 'An alpha -actinin-3 Knockout Mouse Suffers Increased Sarcomeric Damage from Eccentric Exercise', in MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, LIPPINCOTT WILLIAMS & WILKINS, pp. S123 - S124, http://dx.doi.org/10.1249/00005768-200605001-01445
Hu M; Kramer B; Zhang GY; McCowage G; Alexander I; Gunning P; Alexander SI, 2006, 'Long term skin allograft survival in mice with MGMT chimeric bone marrow engraftment', in IMMUNOLOGY AND CELL BIOLOGY, BLACKWELL PUBLISHING, Australian Acad Sci, Canberra, AUSTRALIA, pp. A29 - A29, presented at 24th Annual Scientific Meeting of the Transplantation-Society-of-Australia-and-New-Zealand, Australian Acad Sci, Canberra, AUSTRALIA, 29 March 2006 - 31 March 2006, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000237063000103&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Kramer B; Lemckert F; Alexander I; Gunning P; McCowage G, 2005, 'Methyl-guanine-methyl-transferase (MGMT) expressing transgenic mouse for developing stem cell transplantation models using in vivo selection', in JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Melbourne, AUSTRALIA, pp. 1123 - 1123, presented at 4th Meeting of the Australasian-Gene-Therapy-Society, Melbourne, AUSTRALIA, 27 April 2005 - 29 April 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000231477900038&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Schevzov G; Vrhovski B; Bryce NS; Elmir S; Qiu M; Yang N; Verrills NM; Kavallaris M; Puttur F; Hardeman E; Gunning P, 2004, 'Tropomyosin antibodies identify functionally distinct populations of actin filaments', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Washington, DC, pp. 143A - 143A, presented at Annual Meeting of the American-Society-for-Cell-Biology, Washington, DC, 04 December 2004 - 08 December 2004, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000224648801136&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Gunning P; Schevzov G; Vrhovski B; Hook J; Lemckert F; Weinberger R; Hardemann E, 2004, 'Tropomyosins regulate neuronal shape and dimension', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Washington, DC, pp. 48A - 49A, presented at Annual Meeting of the American-Society-for-Cell-Biology, Washington, DC, 04 December 2004 - 08 December 2004, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000224648800270&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hardeman EC; Nguyen MA; Corbett MA; Ghoddusi M; Joya JE; Gunning PW; North KN, 2003, 'A mouse model for severe actin nemaline myopathy', in NEUROMUSCULAR DISORDERS, PERGAMON-ELSEVIER SCIENCE LTD, SZEGED, HUNGARY, pp. 620 - 620, presented at 8th International Congress of the World-Muscle-Society, SZEGED, HUNGARY, 03 September 2003 - 06 September 2003, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000185007600028&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Schevzov G; Almonte-Baldonado R; Gunning P; Weinberger R, 2002, 'Differential effects of tropomyosin isoforms on neuronal morphogenensis', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, SAN FRANCISCO, CALIFORNIA, pp. 57A - 57A, presented at 42nd Annual Meeting of the American-Society-for-Cell-Biology, SAN FRANCISCO, CALIFORNIA, 14 December 2002 - 18 December 2002, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000179569100320&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Bryce NS; Gunning P; Weinberger RP, 2002, 'Downregulation of non neuronal high molecular weight tropomyosin isoforms is important for neurite outgrowth', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, SAN FRANCISCO, CALIFORNIA, pp. 59A - 59A, presented at 42nd Annual Meeting of the American-Society-for-Cell-Biology, SAN FRANCISCO, CALIFORNIA, 14 December 2002 - 18 December 2002, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000179569100332&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Lloyd CM; Gunning PW, 2000, 'beta- and gamma-actin genes differ in their regulatory mechanisms during myogenesis', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, pp. 75A - 75A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000165525900392&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Weinberger R; Bryce N; Matsumura F; Gunning P, 1999, 'Tropomyosin isoforms can regulate neuronal shape and tension as well actin filament organisation.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, pp. 133A - 133A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083673500771&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Percival J; Weinberger R; Jeffrey P; Gunning P, 1997, 'Spatial segregation of tropomyosin and actin isoforms in synchronized NIH3T3 cells.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, pp. 1569 - 1569, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997YF09601564&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Gunning P; Weinberger R; Schevzov G; Percival J; Hannan A; Dufour C; Qin H; Ferguson V; Jeffrey P, 1996, 'Spatial segregation of microfilament isoforms in neurons and cycling fibroblasts.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, pp. 1972 - 1972, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996WB01801969&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
GUNNING P; HILL M, 1994, 'DIFFERENTIAL DISTRIBUTION OF BETA AND GAMMA ACTIN MESSENGER-RNAS AND ITS REGULATION BY GROWTH-FACTORS', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 536 - 536, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NE25401878&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
DOSREMEDIOS CG; TRAHAIR T; YEOH T; CHANG V; CARTMILL T; GUNNING P, 1992, 'A MYOSIN LIGHT CHAIN-LIKE PROTEIN ASSOCIATED WITH END-STAGE HEART-FAILURE', in JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, pp. R8 - R8, http://dx.doi.org/10.1016/0022-2828(92)91073-E
YEOH T; DOSREMEDIOS CG; CHANG V; GUNNING P, 1991, 'HETEROGENEOUS CHANGES IN CONTRACTILE PROTEIN GENE-EXPRESSION IN HUMAN CARDIOMYOPATHY', in JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, CHAPMAN HALL LTD, pp. 88 - 88, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1991EW83700072&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
COHENHAGUENAUER O; BARTON PJR; VANCONG N; COHEN A; MASSET M; ROBERT B; BUCKINGHAM M; GUNNING P; FREZAL J, 1987, 'CHROMOSOMAL ASSIGNMENT OF 2 MYOSIN ALKALI LIGHT CHAIN GENES ENCODING THE VENTRICULAR SLOW SKELETAL-MUSCLE ISOFORM AND THE ATRIAL FETAL MUSCLE ISOFORM', in CYTOGENETICS AND CELL GENETICS, KARGER, pp. 595 - 595, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1987N171900140&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
GUNNING PW, 1974, 'USE OF DIETHYLPYROCARBONATE TO INVESTIGATE MINOR RNA SPECIES', in PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, PROC AUST BIOCHEMICAL SOC, pp. 76 - 76, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1974T272400156&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Posters
Hardeman EC; Kee AJ; Lucas CA; Chagan J; Gunning PW, 2016, 'Metabolic impact of targeting the tropomyosin/actin cytoskeleton to treat cancer', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, San Francisco, CA, Vol. 27, presented at Annual Meeting of the American-Society-for-Cell-Biology (ASCB), San Francisco, CA, 03 December 2016 - 07 December 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000396046900905&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stehn J; Mariana A; Failes T; Ashokakumar V; Eiffe E; Heaton A; Hook J; Sivanandhan D; Arndt G; Gunning P; Brown D, 2016, 'Synergistic action of first-in-class anti-tropomyosin compound, ATM-3507 (Anisina) and microtubule targeting inhibitors in pre-clinical models of non-small cell lung cancer (NSCLC)', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, Munich, GERMANY, Vol. 69, pp. S116 - S116, presented at 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Munich, GERMANY, 29 November 2016 - 02 December 2016, http://dx.doi.org/10.1016/S0959-8049(16)32946-X
Jalilian I; Oldfield R; Gunning PW; Knothe Tate , 2016, 'Live Multiplexed Imaging of Stem Cell Mechanotransduction and Mechanoadaptation', in Transactions of the Orthopaedic Research Society, AMER SOC CELL BIOLOGY, Orlando, FL, U.S.A., Vol. 41, pp. 0713 - 0713, presented at Orthopaedic Research Society, Orlando, FL, U.S.A., 05 March 2016 - 08 March 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209928400036&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Chisholm OT; Parisio M; Heaton A; Brown D; Gunning P, (eds.), 2015, 'Blended strategies for learning about medicines development', in UNSW Learning and Teaching Forum - Blended Learning: Past, Present and Future, UNSW, UNSW, pp. 74 - 75, presented at UNSW Learning and Teaching Forum - Blended Learning: Past, Present and Future, UNSW, 16 October 2015 - 16 October 2015
Suchowerska A; Chen B; Mueller J; Ittner A; Hardeman E; Ittner L; Janitz M; Gunning P; Fath T, 2013, 'Increased levels of actin filaments containing the tropomyosin Tm5NM1 regulate excitotoxicity in the mouse', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 24, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348705376&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Presentations
Jalilian I; Oldfield R; Gunning P; Knothe Tate ML, 2015, 'Live Multiplexed Imaging of Stem Cell Mechanotransduction and Mechanoadaptation', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Tampa, FL, USA, Vol. 26, presented at Annual Meeting of the Biomedical Engineering Society, Tampa, FL, USA, 06 October 2015 - 10 October 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209928500579&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Heu C; Jalilian I; Kee A; Shevzov G; Whan R; Knothe Tate ML; Gunning P, 2014, 'Impact of the Actin Cytoskeleton on the Mechanical Properties of Cells and Tissues', in Impact of the Actin Cytoskeleton on the Mechanical Properties of Cells and Tissues, 6th AFM BioMed Conference, San Diego, CA, USA, 13-17 December, 2014, poster presentation., presented at 6th AFM BioMed Conference, San Diego, CA, USA, 13-17 December, 2014, poster presentation., 13 December 2014 - 17 December 2014
Schevzov G; Wang B; Hook JW; Tonthat C; Pleines I; Kile B; Hardeman EC; Gunning PW, 2014, 'Distinct Actin Filament Networks Modulate Different Cell Signalling Pathways Involved in Cell Proliferation and Senescence.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094100056&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Jalilian I; Schevzov G; Fath T; Heu C; Bischof L; Vindin H; Stehn JR; Tate MK; Hardeman EC; Gunning PW, 2014, 'Determining the impact of the actin cytoskeleton on the mechanical properties of cells.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094100060&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stehn J; Chen D; Currier M; Eaves D; Desouza M; Cripe T; Gunning PW, 2014, 'Synergistic anti-cancer cell impact of anti-tropomyosin compounds with anti-microtubule drugs.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094104104&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Schevzov G; Wang B; Hook JW; Tonthat C; Pleines I; Kile B; Hardeman EC; Gunning PW, 2014, 'Distinct Actin Filament Networks Modulate Different Cell Signalling Pathways Involved in Cell Proliferation and Senescence.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094106093&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Brayford S; Schevzov G; Hardeman EC; Bear JE; Gunning PW, 2014, 'Tropomyosin 5a/b actin filaments collaborate with arp2/3 actin filaments to regulate cell motility.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094100083&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hardeman EC; Yang L; Kee AJ; Polishchuk E; Polishchuk R; Pleines I; Kile B; Weigert R; Gunning PW, 2014, 'A novel actin filament population defined by the tropomyosin Tm4 regulates ER-to-Golgi trafficking.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094104105&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Jalilian I; Schevzov G; Fath T; Heu C; Bischof L; Vindin H; Stehn JR; Tate MK; Hardeman EC; Gunning PW, 2014, 'Determining the impact of the actin cytoskeleton on the mechanical properties of cells', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094106265&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Abstracts
Ghosh A; Janco M; Bocking T; Gunning PW; Lehman W; Rynkiewicz MJ, 2019, 'Structure of the Tpm3.1 N-Terminus: A New Target for Anti-Cancer Treatment', in BIOPHYSICAL JOURNAL, CELL PRESS, Baltimore, MD, Vol. 116, pp. 253A - 254A, presented at 63rd Annual Meeting of the Biophysical-Society, Baltimore, MD, 02 March 2019 - 06 March 2019, http://dx.doi.org/10.1016/j.bpj.2018.11.1382
Wang Y; Swain A; Stear JH; Bryce NS; Dugina VB; Alieva IB; Cripe TP; Stehn JR; Hardeman EC; Gunning PW, 2017, 'Synergy between anti-tropomyosin and anti-microtubule drugs reveals an interaction between actin and microtubule networks.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 28, presented at Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO), Philadelphia, PA, 02 December 2017 - 06 December 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426664301293&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Meiring JC; Bryce NS; Stear JH; Hardeman EC; Gunning PW, 2017, 'The tropomyosin isoform composition of cellular actin filaments is not a simple function of relative isoform abundance.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 28, presented at Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO), Philadelphia, PA, 02 December 2017 - 06 December 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426664301286&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stehn JR; Stevenson A; Spoerri L; Daignault SM; Gabrielli B; Eiffe E; Gunning PW; Haass N, 2016, 'Developing a new melanoma drug', in AUSTRALASIAN JOURNAL OF DERMATOLOGY, WILEY-BLACKWELL, Vol. 57, pp. 11 - 12, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000374686200029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stehn J; Currier M; Chen D; Eiffe E; Heaton A; Hook J; Gunning P; Cripe T, 2015, 'First-in-class cytoskeletal targeting drug, Anisina, enhances effectiveness of microtubule inhibitors in a preclinical model of neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Fort Lauderdale, FL, Vol. 76, presented at AACR Special Conference on Advances in Pediatric Cancer Research - From Mechanisms and Models to Treatment and Survivorship, Fort Lauderdale, FL, 09 November 2015 - 12 November 2015, http://dx.doi.org/10.1158/1538-7445.PEDCA15-B27
Fath T; Brettle M; Janitz M; Gunning P, 2015, 'Manipulation of the actin cytoskeleton promotes neurite outgrowth on inhibitory substrates', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 311 - 311, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300790&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Obeidy P; Sobey TL; Pandzic E; Nicovich PR; Coster A; Gunning P; Boecking T, 2015, 'Actin Tropomyosin Assembly Intermediates', in BIOPHYSICAL JOURNAL., CELL PRESS, Vol. 108, pp. 298A - 298A, presented at AACR Special Conference on Advances in Pediatric Cancer Research, http://dx.doi.org/10.1016/j.bpj.2014.11.1619
Rynkiewicz M; Stehn J; Gunning P; Lehman W, 2014, 'Structure of the Anti-Cancer Compound TR100 Target-Sites on Tpm3.1 Tropomyosin', in BIOPHYSICAL JOURNAL, CELL PRESS, San Francisco, CA, Vol. 112, pp. 560A - 560A, presented at 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, 15 February 2014 - 19 February 2014, http://dx.doi.org/10.1016/j.bpj.2016.11.3019
Segueira VB; Stehn JR; Haass N; Bonello T; Guven K; Desouza M; Schevzov G; Kottyan G; McCluskey A; Bischof L; Palmer S; Hardeman EC; Allanson M; Reeve V; Weninger W; Cripe TP; Gunning P, 2012, 'Improving the specificity of drugs which target the actin cytoskeleton for cancer therapy', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-5230
Stehn JR; Haass NK; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PR; Han MH; Hill TA; McCluskey A; Palmer S; Hardeman EC; Weninger W; Cripe TR; Gunning P, 2012, 'Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1827
Maytum R; Gunning P; Lin J; Copeland O; Bayliss C; Marston S, 2011, 'Analysis of Tropomyosin (Tm) Isoforms in Heart Muscle by LC/MS and Western Blotting Demonstrates Previously Uncharacterised High-Level Expression of gamma Tm', in BIOPHYSICAL JOURNAL, CELL PRESS, Baltimore, MD, Vol. 100, pp. 371 - 371, presented at 55th Annual Meeting of the Biophysical-Society, Baltimore, MD, 05 March 2011 - 09 March 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306288603140&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Patents
Gunning P; Stehn J; McCluskey A; Butler T; Dixon I, 2007, Compounds for treating Cancer, Australia, Patent No. Australian Provisional Patent Application No 2007906570, Patent Agent:
Gunning P; Stehn J; Schevzov G, 2005, Identification of compounds for the treatment of proliferative disorders, Australia, Patent No. Australian Provisional Patent Application No 2004906888, Patent Agent:
Preprints
Zhao X; Alibhai D; Walsh T; Tarassova N; Birol S; Williams C; Neil C; Aitken E; Waller A; Ballester-Beltran J; Gunning P; Hardeman E; Agbani E; Hers I; Ghevaert C; Poole A, 2021, Platelet generation from circulating megakaryocytes is triggered in the lung vasculature, http://dx.doi.org/10.21203/rs.3.rs-690639/v1
Zhao X; Alibhai D; Walsh T; Tarassova N; Birol S; Williams C; Neil C; Aitken E; Waller A; Ballester-Beltran J; Gunning P; Hardeman E; Agbani E; Hers I; Ghevaert C; Poole A, 2021, Platelet generation from circulating megakaryocytes is triggered in the lung vasculature, http://dx.doi.org/10.1101/2021.11.01.466743
Abouelezz A; Stefen H; Segerstråle M; Micinski D; Minkeviciene R; Hardeman E; Gunning P; Hoogenraad C; Taira T; Fath T; Hotulainen P, 2019, Tropomyosin Tpm3.1 is required to maintain the structure and function of the axon initial segment, http://dx.doi.org/10.1101/711614
Abouelezz A; Stefen H; Segerstråle M; Micinski D; Minkeviciene R; Hardeman EC; Gunning PW; Hoogenraad CC; Taira T; Fath T; Hotulainen P, Tropomyosin Tpm3.1 is Required to Maintain the Structure and Function of the Axon Initial Segment, http://dx.doi.org/10.2139/ssrn.3448139
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