Professor Kerry-Anne Rye

Fields of research: Cardiovascular Medicine and Haematology, Metabolic Medicine, Cardiology (incl. Cardiovascular Diseases)

Contact Details

Phone: +61 2 9385 1219
Fax: 9385 1389
Email: k.rye@unsw.edu.au

Tabs

Main

Biography

Kerry-Anne Rye obtained her PhD from Flinders University of South Australia in 1986 and gained her postdoctoral training at The University of Illinois at Urbana-Champaign. She is a Research Professor, Head of the Lipid Research Group and Deputy Head (Research) in the School of Medical Sciences, University of New South Wales. She is Editor-in-Chief of the Journal of Lipid Research, and an Editorial Board Member of three American Heart Association journals: Arteriosclerosis, Thrombosis and Vascular Biology; The Journal of the American Heart Association and Circulation Research. Professor Rye is the Past Chair of the American Heart Association ATVB Council Women’s Leadership Committee, and a member of the ATVB Leadership Committees, She is the Immediate Past Chair of the Program Committee (ATVB Council nominee) for American Heart Association Scientific Sessions and runs a mentoring program for early career members of the ATVB Council. She is the incoming Chair of the American Heart Association ATVB Council.

Research Program

The overarching goal of Professor Rye's research program is to improve understanding of the causes of heart disease (atherosclerosis) and diabetes and to develop novel strategies for treating both diseases. She was the first to report that the atheroprotective high density lipoproteins (HDLs) in human plasma inhibit inflammation in coronary arteries, and that HDLs also have anti-diabetic properties. Professor Rye studies signal transduction pathways in multiple cell types (macrophages and endothelial cells for heart disease and pancreatic beta cells and skeletal muscle cells for diabetes) and works with novel animal models and state-of-the-art imaging techniques to identify new therapeutic targets for atherosclerosis and diabetes.

Current Postdoctoral Fellows

Blake Cochran

Kwok Leung Ong

Current PhD Students

Bikash Manandhar

Current MSc Students

Dr Liam Guiney

Current ILP Students

Bradley Tucker

Nick Chee

Wei Wang Yeo

Current Honours Students

Thomas King

Shivam Patel

Research Opportunities

There are opportunities for Honours, ILP and PhD students in the Rye Group research program. Contact Kerry-Anne Rye (k.rye@unsw.edu.au) for details of specific projects.

University role:

Head, Lipid Research Group

Awards:

Recent awards include:

2012 American Heart Association ATVB Council Special Recognition Award in Arteriosclerosis

2015 American Heart Association ATVB Council Distinguished Achievement Award

2016 UNSW, Faculty of Medicine, School of Medical Sciences, Researcher of the Year Award

2017 American Heart Association ATVB Council Mentor of Women Award

Research

Teaching & Supervision

I am available to supervise:

Yes

Areas of supervision:

ILP, Honours, Masters, PhD

Currently supervising:

Bikash Manandhar (PhD)

Liam Guiney (MSc)

Rebecca Metzger (ILP)

Wei Ting Tan (ILP)

Yong Chan (ILP)

Supervision keywords:

cardiovascular disease

diabetes

Publications related to this Person

Book Chapters

Siggins S; Rye KA; Olkkonen VM; Jauhiainen M; Ehnholm C, 2008, 'Human Plasma Phospholipid Transfer Protein (PLTP) - Structural and Functional Features', in High-Density Lipoproteins: From Basic Biology to Clinical Aspects, pp. 183 - 205, http://dx.doi.org/10.1002/9783527625178.ch8

Barter PJ; Rye KA, 2008, 'HDL and Atherosclerosis', in High-Density Lipoproteins: From Basic Biology to Clinical Aspects, pp. 491 - 505, http://dx.doi.org/10.1002/9783527625178.ch20

Journal articles

Smith RC; Bulanadi JC; Gill AJ; Rye KA; Hugh T; Proschogo N; Smith SF; Phillips L; Gong X; Julovi SM; Xue A; Moghaddam MJ, 2020, 'Pancreatic adenocarcinoma preferentially takes up and is suppressed by synthetic nanoparticles carrying apolipoprotein A-II and a lipid gemcitabine prodrug in mice', Cancer Letters, vol. 495, pp. 112 - 122, http://dx.doi.org/10.1016/j.canlet.2020.08.045

Ong KL; Wu L; Januszewski AS; O'Connell RL; Xu A; Rye KA; Ma RCW; Li H; Jenkins AJ; Jia W; Keech AC, 2020, 'Relationships of adipocyte-fatty acid binding protein and lipocalin 2 with risk factors and chronic complications in type 2 diabetes and effects of fenofibrate: A fenofibrate Intervention and event lowering in diabetes sub-study', Diabetes Research and Clinical Practice, vol. 169, pp. 108450, http://dx.doi.org/10.1016/j.diabres.2020.108450

Ho JH; Ong KL; Cuesta Torres LF; Liu Y; Adam S; Iqbal Z; Dhage S; Ammori BJ; Syed AA; Rye K-A; Tabet F; Soran H, 2020, 'High-density lipoprotein-associated miRNA is increased following Roux-en-Y gastric bypass surgery for severe obesity.', J Lipid Res, http://dx.doi.org/10.1194/jlr.RA120000963

Meneses-Salas E; García-Melero A; Kanerva K; Blanco-Muñoz P; Morales-Paytuvi F; Bonjoch J; Casas J; Egert A; Beevi SS; Jose J; Llorente-Cortés V; Rye KA; Heeren J; Lu A; Pol A; Tebar F; Ikonen E; Grewal T; Enrich C; Rentero C, 2020, 'Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells', Cellular and Molecular Life Sciences, vol. 77, pp. 2839 - 2857, http://dx.doi.org/10.1007/s00018-019-03330-y

Gierasch LM; Davidson NO; Rye KA; Burlingame AL, 2020, 'Opening ASBMB publications freely to all', Journal of Lipid Research, vol. 61, pp. 969 - 970, http://dx.doi.org/10.1194/JLR.E120000903

Tabet F; Lee S; Zhu W; Levin MG; Toth CL; Cuesta Torres LF; Vinh A; Kim HA; Chu HX; Evans MA; Kuzmich ME; Drummond GR; Remaley AT; Rye KA; Sobey CG; Vickers KC, 2020, 'microRNA-367-3p regulation of GPRC5A is suppressed in ischemic stroke', Journal of Cerebral Blood Flow and Metabolism, vol. 40, pp. 1300 - 1315, http://dx.doi.org/10.1177/0271678X19858637

Gierasch LM; Davidson NO; Rye KA; Burlingame AL, 2020, 'Opening ASBMB publications freely to all', Journal of Biological Chemistry, vol. 295, pp. 7814 - 7815, http://dx.doi.org/10.1074/jbc.E120.014321

Gierasch LM; Davidson NO; Rye KA; Burlingame AL, 2020, 'Opening ASBMB publications freely to all', Molecular and Cellular Proteomics, vol. 19, pp. 914 - 915, http://dx.doi.org/10.1074/mcp.E120.002125

Tucker B; McClelland RL; Allison MA; Budoff MJ; Wu BJ; Barter PJ; Rye KA; Ong KL, 2020, 'Relationship of fibroblast growth factor 21 levels with inflammation, lipoproteins and non-alcoholic fatty liver disease', Atherosclerosis, vol. 299, pp. 38 - 44, http://dx.doi.org/10.1016/j.atherosclerosis.2020.03.009

Gierasch LM; Davidson NO; Rye KA; Burlingame AL, 2020, 'The data must be accessible to all', Journal of Biological Chemistry, vol. 295, pp. 4371, http://dx.doi.org/10.1074/jbc.E120.013060

Ong KL; Chung RWS; Hui N; Festin K; Lundberg AK; Rye KA; Jonasson L; Kristenson M, 2020, 'Usefulness of Certain Protein Biomarkers for Prediction of Coronary Heart Disease', American Journal of Cardiology, vol. 125, pp. 542 - 548, http://dx.doi.org/10.1016/j.amjcard.2019.11.016

Manandhar B; Cochran BJ; Rye KA, 2020, 'Role of High-Density Lipoproteins in Cholesterol Homeostasis and Glycemic Control', Journal of the American Heart Association, vol. 9, pp. e013531, http://dx.doi.org/10.1161/JAHA.119.013531

Shimabukuro Okuda L; Tallada Iborra R; Ramos Pinto P; Fabres Machado U; Corrêa-Giannella ML; Pickford R; Woods T; Brimble MA; Rye KA; Passarelli M, 2020, 'Advanced Glycated apoA-IV Loses Its Ability to Prevent the LPS-Induced Reduction in Cholesterol Efflux-Related Gene Expression in Macrophages', Mediators of Inflammation, vol. 2020, http://dx.doi.org/10.1155/2020/6515401

Gogonea V; Peters J; Gerstenecker GS; Topbas C; Hou L; Combet J; Didonato JA; Smith JD; Rye KA; Hazen SL, 2020, 'Protein backbone and average particle dynamics in reconstituted discoidal and spherical HDL probed by hydrogen deuterium exchange and elastic incoherent neutron scattering', Biomolecules, vol. 10, http://dx.doi.org/10.3390/biom10010121

Gierasch LM; Davidson NO; Rye KA; Burlingame AL, 2020, 'The data must be accessible to all', Molecular and Cellular Proteomics, vol. 19, pp. 569 - 570, http://dx.doi.org/10.1074/mcp.E120.001985

Weaver JC; Ullah I; Qi M; Giannakopoulos B; Rye KA; Kockx M; Kritharides L; Krilis SA, 2020, 'Free thiol β2-GPI (β-2-glycoprotein-I) provides a link between inflammation and oxidative stress in atherosclerotic coronary artery disease', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 40, pp. 2794 - 2804, http://dx.doi.org/10.1161/ATVBAHA.120.315156

Nazir S; Jankowski V; Bender G; Zewinger S; Rye KA; van der Vorst EPC, 2020, 'Interaction between high-density lipoproteins and inflammation: Function matters more than concentration!', Advanced Drug Delivery Reviews, vol. 159, pp. 94 - 119, http://dx.doi.org/10.1016/j.addr.2020.10.006

Tucker B; Li H; Long X; Rye KA; Ong KL, 2019, 'Fibroblast growth factor 21 in non-alcoholic fatty liver disease', Metabolism: Clinical and Experimental, vol. 101, http://dx.doi.org/10.1016/j.metabol.2019.153994

Wu BJ; Li Y; Ong KL; Sun Y; Johns D; Barter PJ; Rye KA, 2019, 'The Cholesteryl Ester Transfer Protein Inhibitor, des-Fluoro-Anacetrapib, Prevents Vein Bypass-induced Neointimal Hyperplasia in New Zealand White Rabbits', Scientific Reports, vol. 9, pp. 16183, http://dx.doi.org/10.1038/s41598-019-52510-0

Magdas A; Ding J; McClelland RL; Allison MA; Barter PJ; Rye KA; Ong KL, 2019, 'The relationship of circulating fibroblast growth factor 21 levels with pericardial fat: The Multi-Ethnic Study of Atherosclerosis', Scientific Reports, vol. 9, pp. 16423, http://dx.doi.org/10.1038/s41598-019-52933-9

Lai YC; Woollard KJ; McClelland RL; Allison MA; Rye KA; Ong KL; Cochran BJ, 2019, 'The association of plasma lipids with white blood cell counts: Results from the Multi-Ethnic Study of Atherosclerosis', Journal of Clinical Lipidology, vol. 13, pp. 812 - 820, http://dx.doi.org/10.1016/j.jacl.2019.07.003

Ong KL; Campbell S; Wu BJ; McClelland RL; Kokkinos J; Szklo M; Polak JF; Allison MA; Rye KA, 2019, 'Relationship of fibroblast growth factor 21 with subclinical atherosclerosis and cardiovascular events: Multi-Ethnic Study of Atherosclerosis', Atherosclerosis, vol. 287, pp. 46 - 53, http://dx.doi.org/10.1016/j.atherosclerosis.2019.06.898

Hou L; Tang S; Wu BJ; Ong KL; Westerterp M; Barter PJ; Cochran BJ; Tabet F; Rye KA, 2019, 'Apolipoprotein A-l improves pancreatic β-cell function independent of the ATP-binding cassette transporters ABCA1 and ABCG1', FASEB Journal, vol. 33, pp. 8479 - 8489, http://dx.doi.org/10.1096/fj.201802512RR

Cuesta Torres LF; Zhu W; Öhrling G; Larsson R; Patel M; Wiese CB; Rye KA; Vickers KC; Tabet F, 2019, 'High-density lipoproteins induce miR-223–3p biogenesis and export from myeloid cells: Role of scavenger receptor BI-mediated lipid transfer', Atherosclerosis, vol. 286, pp. 20 - 29, http://dx.doi.org/10.1016/j.atherosclerosis.2019.04.227

Anuwatmatee S; Allison MA; Shlipak MG; McClelland RL; Kramer H; Tang S; Hou L; Rye KA; Ong KL, 2019, 'Relationship of fibroblast growth factor 21 with kidney function and albuminuria: Multi-ethnic study of atherosclerosis', Nephrology Dialysis Transplantation, vol. 34, pp. 1009 - 1016, http://dx.doi.org/10.1093/ndt/gfy120

Kopecky C; Lytvyn Y; Domenig O; Antlanger M; Kovarik JJ; Kaltenecker CC; Poglitsch M; Perkins BA; Rye KA; Cherney DZI; Säemann MD, 2019, 'Molecular regulation of the renin–angiotensin system by sodium–glucose cotransporter 2 inhibition in type 1 diabetes mellitus', Diabetologia, vol. 62, pp. 1090 - 1093, http://dx.doi.org/10.1007/s00125-019-4871-8

Wu BJ; Sun Y; Ong KL; Li Y; Tang S; Barter PJ; Rye KA, 2019, 'Apolipoprotein A-I Protects Against Pregnancy-Induced Insulin Resistance in Rats', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 39, pp. 1160 - 1171, http://dx.doi.org/10.1161/ATVBAHA.118.312282

Hackett MJ; Hollings A; Majimbi M; Brook E; Cochran B; Giles C; Lam V; Nesbit M; Rye KA; Mamo JCL; Takechi R, 2019, 'Multimodal Imaging Analyses of Brain Hippocampal Formation Reveal Reduced Cu and Lipid Content and Increased Lactate Content in Non-Insulin-Dependent Diabetic Mice', ACS Chemical Neuroscience, vol. 10, pp. 2533 - 2540, http://dx.doi.org/10.1021/acschemneuro.9b00039

Kopecky C; Pandzic E; Parmar A; Szajer J; Lee V; Dupuy A; Arthur A; Fok S; Whan R; Ryder WJ; Rye KA; Cochran BJ, 2019, 'Translocator protein localises to CD11b ⁺ macrophages in atherosclerosis', Atherosclerosis, vol. 284, pp. 153 - 159, http://dx.doi.org/10.1016/j.atherosclerosis.2019.03.011

Ong KL; Hui N; Januszewski AS; Kaakoush NO; Xu A; Fayyad R; DeMicco DA; Jenkins AJ; Keech AC; Waters DD; Barter PJ; Rye KA, 2019, 'High plasma FGF21 levels predicts major cardiovascular events in patients treated with atorvastatin (from the Treating to New Targets [TNT] Study)', Metabolism: Clinical and Experimental, vol. 93, pp. 93 - 99, http://dx.doi.org/10.1016/j.metabol.2018.11.006

Gierasch LM; Davidson NO; Rye KA; Burlingame AL, 2019, 'For the sake of science', Molecular and Cellular Proteomics, vol. 18, pp. 406 - 407, http://dx.doi.org/10.1074/mcp.E119.001384

Gierasch LM; Burlingame AL; Davidson NO; Rye KA, 2019, 'For the sake of science', Journal of Biological Chemistry, vol. 294, pp. 2976, http://dx.doi.org/10.1074/jbc.E119.007916

Cochran B; Tang S; Tabet F; Cuesta Torres L; Wu B; Barter P; Rye K-A, 2019, 'Apolipoprotein A-I enhances insulin-dependent and insulinindependent glucose uptake by skeletal muscle', Scientific Reports, vol. 9, http://dx.doi.org/10.1038/s41598-018-38014-3

Anuwatmatee S; Tang S; Wu BJ; Rye KA; Ong KL, 2019, 'Fibroblast growth factor 21 in chronic kidney disease', Clinica Chimica Acta, vol. 489, pp. 196 - 202, http://dx.doi.org/10.1016/j.cca.2017.11.002

Ong KL; McClelland RL; Allison MA; Kokkinos J; Wu BJ; Barter PJ; Rye KA, 2019, 'Association of elevated circulating fibroblast growth factor 21 levels with prevalent and incident metabolic syndrome: The Multi-Ethnic Study of Atherosclerosis', Atherosclerosis, vol. 281, pp. 200 - 206, http://dx.doi.org/10.1016/j.atherosclerosis.2018.10.011

Yuan D; Wu BJ; Henry A; Rye KA; Ong KL, 2019, 'Role of fibroblast growth factor 21 in gestational diabetes mellitus: A mini-review', Clinical Endocrinology, vol. 90, pp. 47 - 55, http://dx.doi.org/10.1111/cen.13881

Rye KA; Davidson N, 2019, 'A letter from the editors-in-Chief', Journal of Lipid Research, vol. 60, pp. 1, http://dx.doi.org/10.1194/jlr.E091447

Hui N; Barter PJ; Ong KL; Rye KA, 2019, 'Altered HDL metabolism in metabolic disorders: Insights into the therapeutic potential of HDL', Clinical Science, vol. 133, pp. 2221 - 2235, http://dx.doi.org/10.1042/CS20190873

Gierasch LM; Davidson NO; Rye KA; Burlingame AL, 2019, 'For the sake of science', Journal of Lipid Research, vol. 60, pp. 719 - 720, http://dx.doi.org/10.1194/jlr.E093245

Kim WS; He Y; Phan K; Ahmed RM; Rye KA; Piguet O; Hodges JR; Halliday GM, 2018, 'Altered high density lipoprotein composition in behavioral variant frontotemporal dementia', Frontiers in Neuroscience, vol. 12, pp. 847, http://dx.doi.org/10.3389/fnins.2018.00847

Barter PJ; Cochran BJ; Rye KA, 2018, 'CETP inhibition, statins and diabetes', Atherosclerosis, vol. 278, pp. 143 - 146, http://dx.doi.org/10.1016/j.atherosclerosis.2018.09.033

Robinson JG; Williams KJ; Gidding S; Boršen J; Tabas I; Fisher EA; Packard C; Pencina M; Fayad ZA; Mani V; Rye KA; Nordestgaard BG; Tybjærg-Hansen A; Douglas PS; Nicholls SJ; Pagidipati N; Sniderman A, 2018, 'Eradicating the burden of atherosclerotic cardiovascular disease by lowering apolipoprotein b lipoproteins earlier in life', Journal of the American Heart Association, vol. 7, pp. e009778, http://dx.doi.org/10.1161/JAHA.118.009778

Wewege MA; Thom JM; Rye KA; Parmenter BJ, 2018, 'Aerobic, resistance or combined training: A systematic review and meta-analysis of exercise to reduce cardiovascular risk in adults with metabolic syndrome', Atherosclerosis, vol. 274, pp. 162 - 171, http://dx.doi.org/10.1016/j.atherosclerosis.2018.05.002

Barter PJ; Rye KA, 2018, 'Cholesteryl Ester Transfer Protein Inhibitors as Agents to Reduce Coronary Heart Disease Risk', Cardiology Clinics, vol. 36, pp. 299 - 310, http://dx.doi.org/10.1016/j.ccl.2017.12.011

Aleidi SM; Yang A; Sharpe LJ; Rao G; Cochran BJ; Rye KA; Kockx M; Brown AJ; Gelissen IC, 2018, 'The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages', Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, vol. 1863, pp. 359 - 368, http://dx.doi.org/10.1016/j.bbalip.2017.12.011

Ong KL; Morris MJ; McClelland RL; Hughes TM; Maniam J; Fitzpatrick AL; Martin SS; Luchsinger JA; Rapp SR; Hayden KM; Sandfort V; Allison MA; Rye KA, 2018, 'Relationship of Lipids and Lipid-Lowering Medications with Cognitive Function', American Journal of Epidemiology, vol. 187, pp. 767 - 776, http://dx.doi.org/10.1093/aje/kwx329

Choteau SA; Cuesta Torres LF; Barraclough JY; Elder AMM; Martínez GJ; Chen Fan WY; Shrestha S; Ong KL; Barter PJ; Celermajer DS; Rye KA; Patel S; Tabet F, 2018, 'Transcoronary gradients of HDL-associated MicroRNAs in unstable coronary artery disease', International Journal of Cardiology, vol. 253, pp. 138 - 144, http://dx.doi.org/10.1016/j.ijcard.2017.09.190

Hui TH; McClelland RL; Allison MA; Rodriguez CJ; Kronmal RA; Heckbert SR; Michos ED; Barter PJ; Rye KA; Ong KL, 2018, 'The relationship of circulating fibroblast growth factor 21 levels with incident atrial fibrillation: The Multi-Ethnic Study of Atherosclerosis', Atherosclerosis, vol. 269, pp. 86 - 91, http://dx.doi.org/10.1016/j.atherosclerosis.2017.12.026

Iborra RT; Machado-Lima A; Okuda LS; Pinto PR; Nakandakare ER; Machado UF; Correa-Giannella ML; Pickford R; Woods T; Brimble MA; Rye KA; Lu R; Yokoyama S; Passarelli M, 2018, 'AGE-albumin enhances ABCA1 degradation by ubiquitin-proteasome and lysosomal pathways in macrophages', Journal of Diabetes and its Complications, vol. 32, pp. 1 - 10, http://dx.doi.org/10.1016/j.jdiacomp.2017.09.012

Arsenault BJ; Petrides F; Tabet F; Bao W; Hovingh GK; Boekholdt SM; Ramin-Mangata S; Meilhac O; DeMicco D; Rye KA; Waters DD; Kastelein JJP; Barter P; Lambert G, 2018, 'Effect of atorvastatin, cholesterol ester transfer protein inhibition, and diabetes mellitus on circulating proprotein subtilisin kexin type 9 and lipoprotein(a) levels in patients at high cardiovascular risk', Journal of Clinical Lipidology, vol. 12, pp. 130 - 136, http://dx.doi.org/10.1016/j.jacl.2017.10.001

Rosenson RS; Brewer HB; Barter PJ; Björkegren JLM; Chapman MJ; Gaudet D; Kim DS; Niesor E; Rye KA; Sacks FM; Tardif JC; Hegele RA, 2018, 'HDL and atherosclerotic cardiovascular disease: Genetic insights into complex biology', Nature Reviews Cardiology, vol. 15, pp. 9 - 19, http://dx.doi.org/10.1038/nrcardio.2017.115

Perségol L; Darabi M; Dauteuille C; Lhomme M; Chantepie S; Rye KA; Therond P; Chapman MJ; Salvayre R; Nègre-Salvayre A; Lesnik P; Monier S; Kontush A, 2018, 'Small dense HDLs display potent vasorelaxing activity, reflecting their elevated content of sphingosine-1-phosphate', Journal of Lipid Research, vol. 59, pp. 25 - 34, http://dx.doi.org/10.1194/jlr.M076927

Ong KL; Waters DD; Fayyad R; Vogt L; Melamed S; DeMicco DA; Rye KA; Barter PJ, 2018, 'Relationship of high-density lipoprotein cholesterol with renal function in patients treated with atorvastatin', Journal of the American Heart Association, vol. 7, http://dx.doi.org/10.1161/JAHA.117.007387

Shrestha S; Wu BJ; Guiney L; Barter PJ; Rye KA, 2018, 'Cholesteryl ester transfer protein and its inhibitors', Journal of Lipid Research, vol. 59, pp. 772 - 783, http://dx.doi.org/10.1194/jlr.R082735

Zhang M; Lei D; Peng B; Yang M; Zhang L; Charles MA; Rye KA; Krauss RM; Johns DG; Ren G, 2017, 'Assessing the mechanisms of cholesteryl ester transfer protein inhibitors', Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, vol. 1862, pp. 1606 - 1617, http://dx.doi.org/10.1016/j.bbalip.2017.09.004

Chung RWS; Wang Z; Bursill CA; Wu BJ; Barter PJ; Rye KA, 2017, 'Effect of long-term dietary sphingomyelin supplementation on atherosclerosis in mice', PLoS ONE, vol. 12, http://dx.doi.org/10.1371/journal.pone.0189523

da Silva KS; Pinto PR; Fabre NT; Gomes DJ; Thieme K; Okuda LS; Iborra RT; Freitas VG; Shimizu MHM; Teodoro WR; Marie SKN; Woods T; Brimble MA; Pickford R; Rye KA; Okamoto M; Catanozi S; Correa-Giannela ML; Machado UF; Passarelli M, 2017, 'N-acetylcysteine counteracts adipose tissue macrophage infiltration and insulin resistance elicited by advanced glycated albumin in healthy rats', Frontiers in Physiology, vol. 8, http://dx.doi.org/10.3389/fphys.2017.00723

Barter PJ; Rye KA, 2017, 'HDL cholesterol concentration or HDL function: Which matters?', European Heart Journal, vol. 38, pp. 2487 - 2489, http://dx.doi.org/10.1093/eurheartj/ehx274

Ong KL; O'Connell R; Januszewski AS; Jenkins AJ; Xu A; Sullivan DR; Barter PJ; Scott RS; Taskinen MR; Waldman B; Colman PG; Best JD; Simes JR; Rye KA; Keech AC, 2017, 'Baseline circulating FGF21 concentrations and increase after fenofibrate treatment predict more rapid glycemic progression in type 2 diabetes: Results from the FIELD study', Clinical Chemistry, vol. 63, pp. 1261 - 1270, http://dx.doi.org/10.1373/clinchem.2016.270876

Cochran BJ; Ryder W; parmar A; Meikle S; Barter P; Rye K, 2017, 'Determining Glucose Metabolism Kinetics Using 18F-FDG Micro-PET/CT', Journal of Visualized Experiments, vol. 2017, http://dx.doi.org/10.3791/55184

Pandzic E; Gelissen IC; Whan R; Barter PJ; Sviridov D; Gaus K; Rye KA; Cochran BJ, 2017, 'The ATP binding cassette transporter, ABCG1, localizes to cortical actin filaments', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/srep42025

Kokkinos J; Tang S; Rye KA; Ong KL, 2017, 'The role of fibroblast growth factor 21 in atherosclerosis', Atherosclerosis, vol. 257, pp. 259 - 265, http://dx.doi.org/10.1016/j.atherosclerosis.2016.11.033

van der Vorst EPC; Theodorou K; Wu Y; Hoeksema MA; Goossens P; Bursill CA; Aliyev T; Huitema LFA; Tas SW; Wolfs IMJ; Kuijpers MJE; Gijbels MJ; Schalkwijk CG; Koonen DPY; Abdollahi-Roodsaz S; McDaniels K; Wang CC; Leitges M; Lawrence T; Plat J; Van Eck M; Rye KA; Touqui L; de Winther MPJ; Biessen EAL; Donners MMPC, 2017, 'High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling', Cell Metabolism, vol. 25, pp. 197 - 207, http://dx.doi.org/10.1016/j.cmet.2016.10.013

Charlton F; Bobek G; Stait-Gardner T; Price WS; Colafella KMM; Xu B; Makris A; Rye KA; Hennessy A, 2017, 'The protective effect of apolipoprotein in models of trophoblast invasion and preeclampsia', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, vol. 312, pp. R40 - R48, http://dx.doi.org/10.1152/ajpregu.00331.2016

Wu BJ; Li Y; Ong KL; Sun Y; Shrestha S; Hou L; Johns D; Barter PJ; Rye KA, 2017, 'Reduction of in-stent restenosis by cholesteryl ester transfer protein inhibition', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 37, pp. 2333 - 2341, http://dx.doi.org/10.1161/ATVBAHA.117.310051

Melchior JT; Walker RG; Cooke AL; Morris J; Castleberry M; Thompson TB; Jones MK; Song HD; Rye KA; Oda MN; Sorci-Thomas MG; Thomas MJ; Heinecke JW; Mei X; Atkinson D; Segrest JP; Lund-Katz S; Phillips MC; Davidson WS, 2017, 'A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state', Nature Structural and Molecular Biology, vol. 24, pp. 1093 - 1099, http://dx.doi.org/10.1038/nsmb.3501

Cochran BJ; Hou L; Manavalan APC; Moore BM; Tabet F; Sultana A; Torres LC; Tang S; Shrestha S; Senanayake P; Patel M; Ryder WJ; Bongers A; Maraninchi M; Wasinger VC; Westerterp M; Tall AR; Barter PJ; Rye KA, 2016, 'Impact of perturbed pancreatic β-cell cholesterol homeostasis on adipose tissue and skeletal muscle metabolism', Diabetes, vol. 65, pp. 3610 - 3620, http://dx.doi.org/10.2337/db16-0668

Dinnes DLM; White MY; Kockx M; Traini M; Hsieh V; Kim MJ; Hou L; Jessup W; Rye KA; Thaysen-Andersen M; Cordwell SJ; Kritharides L, 2016, 'Human macrophage cathepsin B-mediated C-terminal cleavage of apolipoprotein A-I at Ser²²⁸ severely impairs antiatherogenic capacity', FASEB Journal, vol. 30, pp. 4239 - 4255, http://dx.doi.org/10.1096/fj.201600508R

Gomes DJ; Velosa AP; Okuda LS; Fusco FB; da Silva KS; Pinto PR; Nakandakare ER; Correa-Giannella ML; Woods T; Brimble MA; Pickford R; Rye KA; Teodoro WR; Catanozi S; Passarelli M, 2016, 'Glycated albumin induces lipid infiltration in mice aorta independently of DM and RAS local modulation by inducing lipid peroxidation and inflammation', Journal of Diabetes and its Complications, vol. 30, pp. 1614 - 1621, http://dx.doi.org/10.1016/j.jdiacomp.2016.07.001

Anastasius M; Kockx M; Jessup W; Sullivan D; Rye KA; Kritharides L, 2016, 'Cholesterol efflux capacity: An introduction for clinicians', American Heart Journal, vol. 180, pp. 54 - 63, http://dx.doi.org/10.1016/j.ahj.2016.07.005

Cochran BJ; Ryder WJ; Parmar A; Tang S; Reilhac A; Arthur A; Charil A; Hamze H; Barter PJ; Kritharides L; Meikle SR; Gregoire MC; Rye KA, 2016, 'In vivo PET imaging with [¹⁸F]FDG to explain improved glucose uptake in an apolipoprotein A-I treated mouse model of diabetes', Diabetologia, vol. 59, pp. 1977 - 1984, http://dx.doi.org/10.1007/s00125-016-3993-5

Geronimo FRB; Barter PJ; Rye KA; Heather AK; Shearston KD; Rodgers KJ, 2016, 'Plaque stabilizing effects of apolipoprotein A-IV', Atherosclerosis, vol. 251, pp. 39 - 46, http://dx.doi.org/10.1016/j.atherosclerosis.2016.04.019

Kockx M; Glaros E; Leung B; Ng TW; Berbée JFP; Deswaerte V; Nawara D; Quinn C; Rye KA; Jessup W; Rensen PCN; Meikle PJ; Kritharides L, 2016, 'Low-Density Lipoprotein Receptor-Dependent and Low-Density Lipoprotein Receptor-Independent Mechanisms of Cyclosporin A-Induced Dyslipidemia', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 36, pp. 1338 - 1349, http://dx.doi.org/10.1161/ATVBAHA.115.307030

Siebel AL; Trinh SK; Formosa MF; Mundra PA; Natoli AK; Reddy-Luthmoodoo M; Huynh K; Khan AA; Carey AL; Van Hall G; Cobelli C; Dalla-Man C; Otvos JD; Rye KA; Johansson J; Gordon A; Wong NCW; Sviridov D; Barter P; Duffy SJ; Meikle PJ; Kingwell BA, 2016, 'Effects of the BET-inhibitor, RVX-208 on the HDL lipidome and glucose metabolism in individuals with prediabetes: A randomized controlled trial', Metabolism: Clinical and Experimental, vol. 65, pp. 904 - 914, http://dx.doi.org/10.1016/j.metabol.2016.03.002

Kritharides L; Rye KA; Lambert TJ; Jessup W, 2016, 'Lipidology, cardiovascular risk, and schizophrenia', Current Opinion in Lipidology, vol. 27, pp. 305 - 307, http://dx.doi.org/10.1097/MOL.0000000000000307

Barter PJ; Rye KA, 2016, 'Coronary artery disease: Scavenger receptor class B1-a target to reduce CHD risk?', Nature Reviews Cardiology, vol. 13, pp. 249 - 250, http://dx.doi.org/10.1038/nrcardio.2016.50

Barter PJ; Rye KA, 2016, 'New era of lipid-lowering drugs', Pharmacological Reviews, vol. 68, pp. 458 - 475, http://dx.doi.org/10.1124/pr.115.012203

Sultana A; Cochran BJ; Tabet F; Patel M; Cuesta Torres L; Barter PJ; Rye K, 2016, 'Inhibition of inflammatory signaling pathways in 3T3-L1 adipocytes by apolipoprotein A-I', The FASEB Journal, vol. 30, pp. 2324 - 2335, http://dx.doi.org/10.1096/fj.201500026R

Barter PJ; Rye KA, 2016, 'Cholesteryl ester transfer protein inhibition is not yet dead - Pro', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 36, pp. 439 - 441, http://dx.doi.org/10.1161/ATVBAHA.115.306879

Julovi SM; Xue A; Thanh Le TN; Gill AJ; Bulanadi JC; Patel M; Waddington LJ; Rye KA; Moghaddam MJ; Smith RC, 2016, 'Apolipoprotein A-II plus lipid emulsion enhance cell growth via SR-B1 and target pancreatic cancer in vitro and in vivo', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0151475

Tabet F; Torres LFC; Ong KL; Shrestha S; Choteau SA; Barter PJ; Clifton P; Rye KA, 2016, 'High-density lipoprotein-associated miR-223 is altered after diet-induced weight loss in overweight and obese males', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0151061

Puranik R; Bao S; Bonin AM; Kaur R; Weder JE; Casbolt L; Hambley TW; Lay PA; Barter PJ; Rye KA, 2016, 'A novel class of copper(II)- and zinc(II)-bound non-steroidal anti-inflammatory drugs that inhibits acute inflammation in vivo', Cell and Bioscience, vol. 6, http://dx.doi.org/10.1186/s13578-016-0076-8

Rye KA; Barter PJ; Cochran BJ, 2016, 'Apolipoprotein A-I interactions with insulin secretion and production', Current Opinion in Lipidology, vol. 27, pp. 8 - 13, http://dx.doi.org/10.1097/MOL.0000000000000253

Ong KL; Morris MJ; McClelland RL; Maniam J; Allison MA; Rye KA, 2016, 'Lipids, lipoprotein distribution and depressive symptoms: The multi-ethnic study of atherosclerosis', Translational Psychiatry, vol. 6, pp. e962, http://dx.doi.org/10.1038/tp.2016.232

Rye KA; Barter PJ; Brown AJ, 2015, 'Speed kills in more ways than one: Methamphetamine and atherosclerosis', Atherosclerosis, vol. 243, pp. 654 - 655, http://dx.doi.org/10.1016/j.atherosclerosis.2015.09.034

Barter PJ; Rye KA, 2015, 'Targeting High-density Lipoproteins to Reduce Cardiovascular Risk: What Is the Evidence?', Clinical Therapeutics, vol. 37, pp. 2716 - 2731, http://dx.doi.org/10.1016/j.clinthera.2015.07.021

Bisoendial R; Tabet F; Tak PP; Petrides F; Torres LFC; Hou L; Cook A; Barter PJ; Weninger W; Rye KA, 2015, 'Apolipoprotein A-I Limits the Negative Effect of Tumor Necrosis Factor on Lymphangiogenesis', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 35, pp. 2443 - 2450, http://dx.doi.org/10.1161/ATVBAHA.115.305777

Barter PJ; Tabet F; Rye KA, 2015, 'Reduction in PCSK9 levels induced by anacetrapib: an off-target effect?', Journal of lipid research, vol. 56, pp. 2045 - 2047, http://dx.doi.org/10.1194/jlr.C063768

Wu BJ; Shrestha S; Ong KL; Johns D; Dunn LL; Hou L; Barter PJ; Rye KA, 2015, 'Increasing HDL levels by inhibiting cholesteryl ester transfer protein activity in rabbits with hindlimb ischemia is associated with increased angiogenesis', International Journal of Cardiology, vol. 199, pp. 204 - 212, http://dx.doi.org/10.1016/j.ijcard.2015.07.014

Ong KL; Januszewski AS; O’Connell R; Buizen L; Jenkins AJ; Xu A; Sullivan DR; Barter PJ; Scott RS; Taskinen MR; Rye KA; Keech AC, 2015, 'Relationship of fibroblast growth factor 21 with baseline and new on-study microvascular disease in the Fenofibrate Intervention and Event Lowering in Diabetes study', Diabetologia, vol. 58, pp. 2035 - 2044, http://dx.doi.org/10.1007/s00125-015-3652-2

Ong KL; Ding J; McClelland RL; Cheung BMY; Criqui MH; Barter PJ; Rye KA; Allison MA, 2015, 'Relationship of pericardial fat with lipoprotein distribution: The Multi-Ethnic study of atherosclerosis', Atherosclerosis, vol. 241, pp. 664 - 670, http://dx.doi.org/10.1016/j.atherosclerosis.2015.06.027

Rye KA; Ong KL, 2015, 'HDL function as a predictor of coronary heart disease events: Time to re-assess the HDL hypothesis?', The Lancet Diabetes and Endocrinology, vol. 3, pp. 488 - 489, http://dx.doi.org/10.1016/S2213-8587(15)00205-3

Ong KL; Ding J; McClelland RL; Cheung BMY; Criqui MH; Barter PJ; Rye KA; Allison MA, 2015, 'Relationship of pericardial fat with biomarkers of inflammation and hemostasis, and cardiovascular disease: The Multi-Ethnic Study of Atherosclerosis', Atherosclerosis, vol. 239, pp. 386 - 392, http://dx.doi.org/10.1016/j.atherosclerosis.2015.01.033

Du XM; Kim MJ; Hou L; Le Goff W; Chapman MJ; Van Eck M; Curtiss LK; Burnett JR; Cartland SP; Quinn CM; Kockx M; Kontush A; Rye KA; Kritharides L; Jessup W, 2015, 'HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export', Circulation Research, vol. 116, pp. 1133 - 1142, http://dx.doi.org/10.1161/CIRCRESAHA.116.305485

Ong KL; Januszewski AS; O’Connell R; Jenkins AJ; Xu A; Sullivan DR; Barter PJ; Hung WT; Scott RS; Taskinen MR; Keech AC; Rye KA, 2015, 'The relationship of fibroblast growth factor 21 with cardiovascular outcome events in the Fenofibrate Intervention and Event Lowering in Diabetes study', Diabetologia, vol. 58, pp. 464 - 473, http://dx.doi.org/10.1007/s00125-014-3458-7

Wu BJ; Shrestha S; Ong KL; Johns D; Hou L; Barter PJ; Rye KA, 2015, 'Cholesteryl Ester Transfer Protein Inhibition Enhances Endothelial Repair and Improves Endothelial Function in the Rabbit', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 35, pp. 628 - 636, http://dx.doi.org/10.1161/ATVBAHA.114.304747

Zhang M; Charles R; Tong H; Zhang L; Patel M; Wang F; Rames MJ; Ren A; Rye KA; Qiu X; Johns DG; Charles MA; Ren G, 2015, 'HDL surface lipids mediate CETP binding as revealed by electron microscopy and molecular dynamics simulation', Scientific Reports, vol. 5, http://dx.doi.org/10.1038/srep08741

Besseling J; Ong KL; Huijgen R; Rye KA; Hovingh GK; Hutten BA; Lambert G, 2015, 'The impact of LDLR function on fibroblast growth factor 21 levels', Atherosclerosis, vol. 241, pp. 322 - 325, http://dx.doi.org/10.1016/j.atherosclerosis.2015.05.032

Barter PJ; Nicholls SJ; Kastelein JJP; Rye KA, 2015, 'Is cholesteryl ester transfer protein inhibition an effective strategy to reduce cardiovascular risk?: CETP inhibition as a strategy to reduce cardiovascular risk: The pro case', Circulation, vol. 132, pp. 423 - 432, http://dx.doi.org/10.1161/CIRCULATIONAHA.114.014025

Lambert G; Chatelais M; Petrides F; Passard M; Thedrez A; Rye KA; Schwahn U; Gusarova V; Blom DJ; Sasiela W; Marais AD, 2014, 'Normalization of low-density lipoprotein receptor expression in receptor defective homozygous familial hypercholesterolemia by inhibition of PCSK9 with alirocumab', Journal of the American College of Cardiology, vol. 64, pp. 2299 - 2300, http://dx.doi.org/10.1016/j.jacc.2014.07.995

Vickers KC; Landstreet SR; Levin MG; Shoucri BM; Toth CL; Taylor RC; Palmisano BT; Tabet F; Cui HL; Rye KA; Sethupathy P; Remaley AT, 2014, 'MicroRNA-223 coordinates cholesterol homeostasis', Proceedings of the National Academy of Sciences of the United States of America, vol. 111, pp. 14518 - 14523, http://dx.doi.org/10.1073/pnas.1215767111

Ong KL; McClelland RL; Rye KA; Cheung BMY; Post WS; Vaidya D; Criqui MH; Cushman M; Barter PJ; Allison MA, 2014, 'The relationship between insulin resistance and vascular calcification in coronary arteries, and the thoracic and abdominal aorta: The multi-ethnic study of atherosclerosis', Atherosclerosis, vol. 236, pp. 257 - 262, http://dx.doi.org/10.1016/j.atherosclerosis.2014.07.015

Cochran BJ; Bisoendial RJ; Hou L; Glaros E; Rossy J; Thomas SR; Barter PJ; Rye KA, 2014, 'Apolipoprotein a-I increases insulin secretion and production from pancreatic β-cells via a g-protein-camp-PKA-FOXO1-dependent mechanism', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 34, pp. 2261 - 2267, http://dx.doi.org/10.1161/ATVBAHA.114.304131

Lambert G; Petrides F; Chatelais M; Blom DJ; Choque B; Tabet F; Wong G; Rye KA; Hooper AJ; Burnett JR; Barter PJ; Marais AD, 2014, 'Elevated plasma PCSK9 level is equally detrimental for patients with nonfamilial hypercholesterolemia and heterozygous familial hypercholesterolemia, irrespective of low-density lipoprotein receptor defects', Journal of the American College of Cardiology, vol. 63, pp. 2365 - 2373, http://dx.doi.org/10.1016/j.jacc.2014.02.538

Ong KL; Waters DD; Messig M; Demicco DA; Rye KA; Barter PJ, 2014, 'Effect of change in body weight on incident diabetes mellitus in patients with stable coronary artery disease treated with atorvastatin (from the Treating to New Targets Study)', American Journal of Cardiology, vol. 113, pp. 1593 - 1598, http://dx.doi.org/10.1016/j.amjcard.2014.02.011

Ong KL; Allison MA; Cheung BMY; Wu BJ; Barter PJ; Rye KA, 2014, 'The relationship between total Bilirubin levels and total mortality in older adults: The United States national health and nutrition examination survey (NHANES) 1999-2004', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0094479

Rye KA, 2014, 'Biomarkers associated with high-density lipoproteins in atherosclerotic kidney disease', Clinical and Experimental Nephrology, vol. 18, pp. 247 - 250, http://dx.doi.org/10.1007/s10157-013-0865-x

Wu BJ; Ong KL; Shrestha S; Chen K; Tabet F; Barter PJ; Rye KA, 2014, 'Inhibition of arthritis in the lewis rat by apolipoprotein A-I and reconstituted high-density lipoproteins', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 34, pp. 543 - 551, http://dx.doi.org/10.1161/ATVBAHA.113.302832

Charlton F; Tooher J; Rye KA; Hennessy A, 2014, 'Cardiovascular risk, lipids and pregnancy: Preeclampsia and the risk of later life cardiovascular disease', Heart Lung and Circulation, vol. 23, pp. 203 - 212, http://dx.doi.org/10.1016/j.hlc.2013.10.087

Tabet F; Vickers KC; Cuesta Torres LF; Wiese CB; Shoucri BM; Lambert G; Catherinet C; Prado-Lourenco L; Levin MG; Thacker S; Sethupathy P; Barter PJ; Remaley AT; Rye KA, 2014, 'HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells', Nature Communications, vol. 5, http://dx.doi.org/10.1038/ncomms4292

Rye KA; Barter PJ, 2014, 'Thematic review series: High density lipoprotein structure, function, and metabolism cardioprotective functions of HDLs 1', Journal of Lipid Research, vol. 55, pp. 168 - 179, http://dx.doi.org/10.1194/jlr.R039297

Rye KA; Barter PJ, 2014, 'Regulation of high-density lipoprotein metabolism', Circulation Research, vol. 114, pp. 143 - 156, http://dx.doi.org/10.1161/CIRCRESAHA.114.300632

Vickers KC; Rye KA; Tabet F, 2014, 'MicroRNAs in the onset and development of cardiovascular disease', Clinical Science, vol. 126, pp. 183 - 194, http://dx.doi.org/10.1042/CS20130203

McGrath KC; Li XH; Whitworth PT; Kasz R; Tan JT; McLennan SV; Celermajer DS; Barter PJ; Rye KA; Heather AK, 2014, 'High density lipoproteins improve insulin sensitivity in high-fat diet-fed mice by suppressing hepatic inflammation', Journal of Lipid Research, vol. 55, pp. 421 - 430, http://dx.doi.org/10.1194/jlr.M043281

Rye KA, 2013, 'High density lipoprotein structure, function, and metabolism: A new Thematic Series', Journal of Lipid Research, vol. 54, pp. 2031 - 2033, http://dx.doi.org/10.1194/jlr.E041350

Ong KL; Allison MA; Cheung BMY; Wu BJ; Barter PJ; Rye KA, 2013, 'Trends in C-reactive protein levels in US adults from 1999 to 2010', American Journal of Epidemiology, vol. 177, pp. 1430 - 1442, http://dx.doi.org/10.1093/aje/kws443

Brown BE; Nobecourt E; Zeng J; Jenkins AJ; Rye KA; Davies MJ, 2013, 'Apolipoprotein A-I glycation by Glucose and Reactive Aldehydes Alters Phospholipid Affinity but Not Cholesterol Export from Lipid-Laden Macrophages', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0065430

Yu S; Youssef P; Tabet F; Rye K; Bisoendial R, 2013, 'HIGH DENSITY LIPOPROTEIN FUNCTION IN RHEUMATOID ARTHRITIS BEFORE AND AFTER TNF alpha INHIBITION', INTERNAL MEDICINE JOURNAL, vol. 43, pp. 9 - 9, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318185100029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Mulay V; Wood P; Manetsch M; Darabi M; Cairns R; Hoque M; Chan KC; Reverter M; Álvarez-Guaita A; Rye KA; Rentero C; Heeren J; Enrich C; Grewal T, 2013, 'Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and HuH7 Cells', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0062667

Huijgen R; Boekholdt SM; Arsenault BJ; Bao W; Davaine JM; Tabet F; Petrides F; Rye KA; DeMicco DA; Barter PJ; Kastelein JJP; Lambert G, 2013, 'Erratum: Plasma PCSK9 levels and clinical outcomes in the TNT (Treating to New Targets) Trial (Journal of the American College of Cardiology (2012) 59 (1778-1784))', Journal of the American College of Cardiology, vol. 61, pp. 1751, http://dx.doi.org/10.1016/j.jacc.2013.04.002

Van Der Vorst EPC; Vanags LZ; Dunn LL; Prosser HC; Rye KA; Bursill CA, 2013, 'High-density lipoproteins suppress chemokine expression and proliferation in human vascular smooth muscle cells', FASEB Journal, vol. 27, pp. 1413 - 1425, http://dx.doi.org/10.1096/fj.12-212753

Chung RWS; Kamili A; Tandy S; Weir JM; Gaire R; Wong G; Meikle PJ; Cohn JS; Rye KA, 2013, 'Dietary Sphingomyelin Lowers Hepatic Lipid Levels and Inhibits Intestinal Cholesterol Absorption in High-Fat-Fed Mice', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0055949

Wu BJ; Chen K; Shrestha S; Ong KL; Barter PJ; Rye KA, 2013, 'High-density lipoproteins inhibit vascular endothelial inflammation by increasing 3β-hydroxysteroid-[INCREMENT]24 reductase expression and inducing heme oxygenase-1', Circulation Research, vol. 112, pp. 278 - 288, http://dx.doi.org/10.1161/CIRCRESAHA.111.300104

Hadfield KA; Pattison DI; Brown BE; Hou L; Rye KA; Davies MJ; Hawkins CL, 2013, 'Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: Comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)', Biochemical Journal, vol. 449, pp. 531 - 542, http://dx.doi.org/10.1042/BJ20121210

Ong KL; Wu BJ; Cheung BMY; Barter PJ; Rye KA, 2013, 'Arthritis: Its prevalence, Risk factors, And association with cardiovascular diseases in the United States, 1999 to 2008', Annals of Epidemiology, vol. 23, pp. 80 - 86, http://dx.doi.org/10.1016/j.annepidem.2012.11.008

Ong KL; Rye KA; O'Connell R; Jenkins AJ; Brown C; Xu A; Sullivan DR; Barter PJ; Keech AC, 2012, 'Long-term fenofibrate therapy increases fibroblast growth factor 21 and retinol-binding protein 4 in subjects with type 2 diabetes', Journal of Clinical Endocrinology and Metabolism, vol. 97, pp. 4701 - 4708, http://dx.doi.org/10.1210/jc.2012-2267

Barter PJ; Rye KA; Beltangady MS; Ports WC; Duggan WT; Boekholdt SM; DeMicco DA; Kastelein JJP; Shear CL, 2012, 'Relationship between atorvastatin dose and the harm caused by torcetrapib', Journal of Lipid Research, vol. 53, pp. 2436 - 2442, http://dx.doi.org/10.1194/jlr.P026328

Barter PJ; Rye KA, 2012, 'Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk', Journal of Lipid Research, vol. 53, pp. 1755 - 1766, http://dx.doi.org/10.1194/jlr.R024075

Rye KA; Barter PJ, 2012, 'The inhibition of cholesteryl ester transfer protein: A long and winding road', Journal of Lipid Research, vol. 53, pp. 1039 - 1041, http://dx.doi.org/10.1194/jlr.E027334

Borthwick F; Warnakula S; Mangat R; Uwiera RR; Russell JC; Kelly SE; Lee CY; Hryshko L; Mamo JCL; Rye KA; Lopaschuk GD; Proctor SD, 2012, 'ApoA-1 infusion reduces arterial cholesterol and myocardial lesions in a rat model of cardiac dysfunction and insulin resistance', Atherosclerosis, vol. 222, pp. 402 - 408, http://dx.doi.org/10.1016/j.atherosclerosis.2012.03.006

Huijgen R; Boekholdt SM; Arsenault BJ; Bao W; Davaine JM; Tabet F; Petrides F; Rye KA; Demicco DA; Barter PJ; Kastelein JJP; Lambert G, 2012, 'Plasma PCSK9 levels and clinical outcomes in the TNT (Treating to New Targets) trial: A nested case-control study', Journal of the American College of Cardiology, vol. 59, pp. 1778 - 1784, http://dx.doi.org/10.1016/j.jacc.2011.12.043

Tso C; Rye KA; Barter P, 2012, 'Phenotypic and functional changes in blood monocytes following adherence to endothelium', PLoS ONE, vol. 7, http://dx.doi.org/10.1371/journal.pone.0037091

Drew BG; Rye KA; Duffy SJ; Barter P; Kingwell BA, 2012, 'The emerging role of HDL in glucose metabolism', Nature Reviews Endocrinology, vol. 8, pp. 237 - 245, http://dx.doi.org/10.1038/nrendo.2011.235

Gao X; Gu H; Li G; Rye KA; Zhang DW, 2012, 'Identification of an amino acid residue in ATP-binding cassette transport G1 critical for mediating cholesterol efflux', Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, vol. 1821, pp. 552 - 559, http://dx.doi.org/10.1016/j.bbalip.2011.07.012

Rye KA; Barter PJ, 2012, 'Predictive value of different HDL particles for the protection against or risk of coronary heart disease', Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, vol. 1821, pp. 473 - 480, http://dx.doi.org/10.1016/j.bbalip.2011.10.012

Wu BJ; Chen K; Barter PJ; Rye KA, 2012, 'Niacin inhibits vascular inflammation via the induction of heme oxygenase-1', Circulation, vol. 125, pp. 150 - 158, http://dx.doi.org/10.1161/CIRCULATIONAHA.111.053108

Zhang L; Yan F; Zhang S; Lei D; Charles MA; Cavigiolio G; Oda M; Krauss RM; Weisgraber KH; Rye KA; Pownall HJ; Qiu X; Ren G, 2012, 'Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein', Nature Chemical Biology, vol. 8, pp. 342 - 349, http://dx.doi.org/10.1038/nchembio.796

Ong KL; Barter PJ; Rye KA, 2011, 'Response to statin use and serum bilirubin levels', Atherosclerosis, vol. 219, pp. 392, http://dx.doi.org/10.1016/j.atherosclerosis.2011.09.007

Di Bartolo BA; Vanags LZ; Tan JT; Bao S; Rye KA; Barter PJ; Bursill CA, 2011, 'The apolipoprotein A-I mimetic peptide, ETC-642, reduces chronic vascular inflammation in the rabbit.', Lipids in health and disease, vol. 10, pp. 224, http://dx.doi.org/10.1186/1476-511X-10-224

Barter P; Rye KA, 2011, 'Cholesteryl ester transfer protein inhibition to reduce cardiovascular risk: Where are we now?', Trends in Pharmacological Sciences, vol. 32, pp. 694 - 699, http://dx.doi.org/10.1016/j.tips.2011.07.004

Ong KL; Tso AWK; Xu A; Law LSC; Li M; Wat NMS; Rye KA; Lam TH; Cheung BMY; Lam KSL, 2011, 'Evaluation of the combined use of adiponectin and C-reactive protein levels as biomarkers for predicting the deterioration in glycaemia after a median of 5.4 years', Diabetologia, vol. 54, pp. 2552 - 2560, http://dx.doi.org/10.1007/s00125-011-2227-0

Barter PJ; Rye KA; Tardif JC; Waters DD; Matthijs BS; Breazna A; Kastelein JJP, 2011, 'Effect of torcetrapib on glucose, insulin, and hemoglobin a1c in subjects in the investigation of lipid level management to understand its impact in atherosclerotic events (Illuminate) Trial', Circulation, vol. 124, pp. 555 - 562, http://dx.doi.org/10.1161/CIRCULATIONAHA.111.018259

Di Bartolo BA; Nicholls SJ; Bao S; Rye KA; Heather AK; Barter PJ; Bursill C, 2011, 'The apolipoprotein A-I mimetic peptide ETC-642 exhibits anti-inflammatory properties that are comparable to high density lipoproteins', Atherosclerosis, vol. 217, pp. 395 - 400, http://dx.doi.org/10.1016/j.atherosclerosis.2011.04.001

Kitajima K; Miura SI; Yamauchi T; Uehara Y; Kiya Y; Rye KA; Kadowaki T; Saku K, 2011, 'Possibility of increasing cholesterol efflux by adiponectin and its receptors through the ATP binding cassette transporter A1 in HEK293T cells', Biochemical and Biophysical Research Communications, vol. 411, pp. 305 - 311, http://dx.doi.org/10.1016/j.bbrc.2011.06.131

Wood P; Mulay V; Darabi M; Chan KC; Heeren J; Pol A; Lambert G; Rye KA; Enrich C; Grewal T, 2011, 'Ras/mitogen-activated protein kinase (MAPK) signaling modulates protein stability and cell surface expression of scavenger receptor SR-BI', Journal of Biological Chemistry, vol. 286, pp. 23077 - 23092, http://dx.doi.org/10.1074/jbc.M111.236398

Reimers GJ; Jackson CL; Rickards J; Chan PY; Cohn JS; Rye KA; Barter PJ; Rodgers KJ, 2011, 'Inhibition of rupture of established atherosclerotic plaques by treatment with apolipoprotein A-I', Cardiovascular Research, vol. 91, pp. 37 - 44, http://dx.doi.org/10.1093/cvr/cvr057

Tabet F; Lambert G; Cuesta Torres LF; Hou L; Sotirchos I; Touyz RM; Jenkins AJ; Barter PJ; Rye KA, 2011, 'Lipid-free apolipoprotein A-I and discoidal reconstituted high-density lipoproteins differentially inhibit glucose-induced oxidative stress in human macrophages', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 31, pp. 1192 - 1200, http://dx.doi.org/10.1161/ATVBAHA.110.222000

Wu Z; Gogonea V; Lee X; May RP; Pipich V; Wagner MA; Undurti A; Tallant TC; Baleanu-Gogonea C; Charlton F; Ioffe A; DiDonato JA; Rye KA; Hazen SL, 2011, 'The low resolution structure of ApoA1 in spherical high density lipoprotein revealed by small angle neutron scattering', Journal of Biological Chemistry, vol. 286, pp. 12495 - 12508, http://dx.doi.org/10.1074/jbc.M110.209130

Ong KL; Wu BJ; Cheung BMY; Barter PJ; Rye KA, 2011, 'Association of lower total bilirubin level with statin usage: The United States National Health and Nutrition Examination Survey 1999-2008', Atherosclerosis, vol. 219, pp. 728 - 733, http://dx.doi.org/10.1016/j.atherosclerosis.2011.07.094

Zhang L; Song J; Cavigiolio G; Ishida BY; Zhang S; Kane JP; Weisgraber KH; Oda MN; Rye KA; Pownall HJ; Ren G, 2011, 'Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy', Journal of Lipid Research, vol. 52, pp. 175 - 184, http://dx.doi.org/10.1194/jlr.D010959

Elliott DA; Tsoi K; Holinkova S; Chan LL; Kim WS; Halliday GM; Rye K; Garner B, 2011, 'Isoform-specific proteolysis of apolipoprotein-E in the brain', Neurobiology of Aging, vol. 32, pp. 257 - 271, http://dx.doi.org/10.1016/j.neurobiolaging.2009.02.006

Bursill CA; Castro ML; Beattie DT; Nakhla S; Van Der Vorst E; Heather AK; Barter PJ; Rye KA, 2010, 'High-density lipoproteins suppress chemokines and chemokine receptors in vitro and in vivo', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 30, pp. 1773 - 1778, http://dx.doi.org/10.1161/ATVBAHA.110.211342

Imaizumi S; Kiya Y; Miura SI; Zhang B; Matsuo Y; Uehara Y; Rye KA; Saku K, 2010, 'Pharmacological intervention using reconstituted high-density lipoprotein changes in the lipid profile in spontaneously hypersensitive rats', Clinical and Experimental Hypertension, vol. 32, pp. 202 - 208, http://dx.doi.org/10.3109/10641960903265196

Wu BJ; Yan L; Charlton F; Witting P; Barter PJ; Rye KA, 2010, 'Evidence that niacin inhibits acute vascular inflammation and improves endothelial dysfunction independent of changes in plasma lipids', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 30, pp. 968 - 975, http://dx.doi.org/10.1161/ATVBAHA.109.201129

Nobécourt E; Tabet F; Lambert G; Puranik R; Bao S; Yan L; Davies MJ; Brown BE; Jenkins AJ; Dusting GJ; Bonnet DJ; Curtiss LK; Barter PJ; Rye KA, 2010, 'Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 30, pp. 766 - 772, http://dx.doi.org/10.1161/ATVBAHA.109.201715

de Souza JA; Vindis C; Nègre-Salvayre A; Rye KA; Couturier M; Therond P; Chantepie S; Salvayre R; Chapman MJ; Kontush A, 2010, 'Small, dense HDL 3 particles attenuate apoptosis in endothelial cells: Pivotal role of apolipoprotein A-I', Journal of Cellular and Molecular Medicine, vol. 14, pp. 608 - 620, http://dx.doi.org/10.1111/j.1582-4934.2009.00713.x

Tabet F; Remaley AT; Segaliny AI; Millet J; Yan L; Nakhla S; Barter PJ; Rye KA; Lambert G, 2010, 'The 5A apolipoprotein A-I mimetic peptide displays antiinflammatory and antioxidant properties in vivo and in vitro', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 30, pp. 246 - 252, http://dx.doi.org/10.1161/ATVBAHA.109.200196

Chan DC; Hamilton SJ; Rye KA; Chew GT; Jenkins AJ; Lambert G; Watts GF, 2010, 'Fenofibrate concomitantly decreases serum proprotein convertase subtilisin/kexin type 9 and very-low-density lipoprotein particle concentrations in statin-treated type 2 diabetic patients', Diabetes, Obesity and Metabolism, vol. 12, pp. 752 - 756, http://dx.doi.org/10.1111/j.1463-1326.2010.01229.x

Patel S; Di bartolo B; Nakhla S; Heather A; Mitchell T; Jessup W; Celermajer D; Barter P; Rye K, 2010, 'Anti-inflammatory effects of apolipoprotein A-I in the rabbit', Atherosclerosis, vol. 212, pp. 392 - 397, http://dx.doi.org/10.1016/j.atherosclerosis.2010.05.035

Fryirs MA; Barter P; Appavoo M; Tuch BE; Tabet F; Heather AK; Rye K, 2010, 'Effects of High-Density Lipoproteins on Pancreatic -Cell Insulin Secretion', Arteriosclerosis, Thrombosis and Vascular Biology, vol. 30, pp. 1642 - 1648, http://dx.doi.org/10.1161/ATVBAHA.110.207373

Zerrad-Saadi A; Therond P; Chantepie S; Couturier M; Rye KA; Chapman MJ; Kontush A, 2009, 'HDL3-mediated inactivation of LDL-associated phospholipid hydroperoxides is determined by the redox status of apolipoprotein A-I and HDL particle surface lipid rigidity: Relevance to inflammation and atherogenesis', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 29, pp. 2169 - 2175, http://dx.doi.org/10.1161/ATVBAHA.109.194555

Chan DC; Watts GF; Ooi EMM; Rye KA; Ji J; Johnson AG; Barrett PHR, 2009, 'Regulatory effects of fenofibrate and atorvastatin on lipoprotein A-I and lipoprotein A-I:A-II kinetics in the metabolic syndrome', Diabetes Care, vol. 32, pp. 2111 - 2113, http://dx.doi.org/10.2337/dc09-0519

Chan DC; Lambert G; Barrett PHR; Rye KA; Ooi EMM; Watts GF, 2009, 'Plasma proprotein convertase subtilisin/kexin type 9: A marker of LDL apolipoprotein B-100 catabolism?', Clinical Chemistry, vol. 55, pp. 2049 - 2052, http://dx.doi.org/10.1373/clinchem.2009.128645

Peshavariya H; Dusting GJ; Di Bartolo B; Rye KA; Barter PJ; Jiang F, 2009, 'Reconstituted high-density lipoprotein suppresses leukocyte NADPH oxidase activation by disrupting lipid rafts', Free Radical Research, vol. 43, pp. 772 - 782, http://dx.doi.org/10.1080/10715760903045304

McGrath KCY; Li XH; Puranik R; Liong EC; Tan JTM; Dy VM; Dibartolo BA; Barter PJ; Rye KA; Heather AK, 2009, 'Role of 3β-hydroxysteroid-Δ24 reductase in mediating antiinflammatory effects of high-density lipoproteins in endothelial cells', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 29, pp. 877 - 882, http://dx.doi.org/10.1161/ATVBAHA.109.184663

Fryirs M; Barter PJ; Rye KA, 2009, 'Cholesterol metabolism and pancreatic β-cell function', Current Opinion in Lipidology, vol. 20, pp. 159 - 164, http://dx.doi.org/10.1097/MOL.0b013e32832ac180

Rye KA; Bursill CA; Lambert G; Tabet F; Barter PJ, 2009, 'The metabolism and anti-atherogenic properties of HDL', Journal of Lipid Research, vol. 50, http://dx.doi.org/10.1194/jlr.R800034-JLR200

Patel S; Drew BG; Nakhla S; Duffy SJ; Murphy AJ; Barter PJ; Rye KA; Chin-Dusting J; Hoang A; Sviridov D; Celermajer DS; Kingwell BA, 2009, 'Reconstituted High-Density Lipoprotein Increases Plasma High-Density Lipoprotein Anti-Inflammatory Properties and Cholesterol Efflux Capacity in Patients With Type 2 Diabetes', Journal of the American College of Cardiology, vol. 53, pp. 962 - 971, http://dx.doi.org/10.1016/j.jacc.2008.12.008

Lambert G; Charlton F; Rye KA; Piper DE, 2009, 'Molecular basis of PCSK9 function', Atherosclerosis, vol. 203, pp. 1 - 7, http://dx.doi.org/10.1016/j.atherosclerosis.2008.06.010

Kiya Y; Miura SI; Imaizumi S; Uehara Y; Matsuo Y; Abe S; Jimi S; Urata H; Rye KA; Saku K, 2009, 'Reconstituted high-density lipoprotein attenuates postinfarction left ventricular remodeling in rats', Atherosclerosis, vol. 203, pp. 137 - 144, http://dx.doi.org/10.1016/j.atherosclerosis.2008.05.056

Tabet F; Rye KA, 2009, 'High-density lipoproteins, inflammation and oxidative stress', Clinical Science, vol. 116, pp. 87 - 98, http://dx.doi.org/10.1042/CS20080106

Patel S; Puranik R; Nakhla S; Lundman P; Stocker R; Wang X; Lambert G; Rye KA; Barter P; Nicholls S; Celermajer D, 2009, 'Acute hypertriglyceridaemia in humans increases the triglyceride content and decreases the anti-intlammatory capacity of high density lipoproteins', Atherosclerosis, vol. 204, pp. 424 - 428, http://dx.doi.org/10.1016/j.atherosclerosis.2008.07.047

Rye KA; Barter PJ, 2008, 'Antiinflammatory actions of HDL. A new insight', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 28, pp. 1890 - 1891, http://dx.doi.org/10.1161/ATVBAHA.108.173575

Silva RAGD; Huang R; Morris J; Fang J; Gracheva EO; Ren G; Kontush A; Jerome WG; Rye KA; Davidson WS, 2008, 'Structure of apolipoprotein A-I in spherical high density lipoproteins of different sizes', Proceedings of the National Academy of Sciences of the United States of America, vol. 105, pp. 12176 - 12181, http://dx.doi.org/10.1073/pnas.0803626105

Nobécourt E; Zeng J; Davies MJ; Brown BE; Yadav S; Barter PJ; Rye KA, 2008, 'Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I', Diabetologia, vol. 51, pp. 1008 - 1017, http://dx.doi.org/10.1007/s00125-008-0986-z

Lambert G; Ancellin N; Charlton F; Comas D; Pilot J; Keech A; Patel S; Sullivan DR; Cohn JS; Rye KA; Barter PJ, 2008, 'Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment', Clinical Chemistry, vol. 54, pp. 1038 - 1045, http://dx.doi.org/10.1373/clinchem.2007.099747

Imaizumi S; Miura SI; Nakamura K; Kiya Y; Uehara Y; Zhang B; Matsuo Y; Urata H; Ideishi M; Rye KA; Sata M; Saku K, 2008, 'Antiarrhythmogenic Effect of Reconstituted High-Density Lipoprotein Against Ischemia/Reperfusion in Rats', Journal of the American College of Cardiology, vol. 51, pp. 1604 - 1612, http://dx.doi.org/10.1016/j.jacc.2007.12.040

Uehara Y; Tsuboi Y; Zhang B; Miura SI; Baba Y; Higuchi MA; Yamada T; Rye KA; Saku K, 2008, 'POPC/apoA-I discs as a potent lipoprotein modulator in Tangier disease', Atherosclerosis, vol. 197, pp. 283 - 289, http://dx.doi.org/10.1016/j.atherosclerosis.2007.04.025

Homer VM; Marais AD; Charlton F; Laurie AD; Hurndell N; Scott R; Mangili F; Sullivan DR; Barter PJ; Rye KA; George PM; Lambert G, 2008, 'Identification and characterization of two non-secreted PCSK9 mutants associated with familial hypercholesterolemia in cohorts from New Zealand and South Africa', Atherosclerosis, vol. 196, pp. 659 - 666, http://dx.doi.org/10.1016/j.atherosclerosis.2007.07.022

Barter PJ; Rye KA, 2008, 'Is there a role for fibrates in the management of dyslipidemia in the metabolic syndrome?', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 28, pp. 39 - 46, http://dx.doi.org/10.1161/ATVBAHA.107.148817

Puranik R; Bao S; Nobecourt E; Nicholls SJ; Dusting GJ; Barter PJ; Celermajer DS; Rye KA, 2008, 'Low dose apolipoprotein A-I rescues carotid arteries from inflammation in vivo', Atherosclerosis, vol. 196, pp. 240 - 247, http://dx.doi.org/10.1016/j.atherosclerosis.2007.05.008

Settasatian N; Barter PJ; Rye KA, 2008, 'Remodeling of apolipoprotein E-containing spherical reconstituted high density lipoproteins by phospholipid transfer protein', Journal of Lipid Research, vol. 49, pp. 115 - 126, http://dx.doi.org/10.1194/jlr.M700220-JLR200

Chan LL; Kim WS; Kwok JB; Hill AF; Cappai R; Rye K; Garner B, 2008, 'ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro', Journal of Neurochemistry, vol. 106, pp. 793 - 804, http://dx.doi.org/10.1111/j.1471-4159.2008.05433.x

Glaros EN; Kim WS; Rye K; Shayman J; Garner B, 2008, 'Reduction of plasma glycosphingolipid levels has no impact on atherosclerosis in apolipoprotein E-null mice', Journal of Lipid Research, vol. 49, pp. 1677 - 1681, http://dx.doi.org/10.1194/jlr.E800005-JLR200

Glaros EN; Kim WS; Quinn CM; Jessup W; Rye K; Garner B, 2008, 'Myriocin slows the progression of established atherosclerotic lesions in apolipoprotein E gene knockout mice', Journal of Lipid Research, vol. 49, pp. 324 - 331, http://dx.doi.org/10.1194/jlr.M700261-JLR200

Kim WS; Elliott DA; Kockx M; Kritharides L; Rye K; Jans D; Garner B, 2008, 'Analysis of apolipoprotein E nuclear localization using green fluorescent protein and biotinylation approaches', Biochemical Journal, vol. 409, pp. 701 - 709, http://dx.doi.org/10.1042/BJ20071261

Ng TWK; Watts GF; Barrett PHR; Rye KA; Chan DC, 2007, 'Effect of weight loss on LDL and HDL kinetics in the metabolic syndrome: Associations with changes in plasma retinol-binding protein-4 and adiponectin levels', Diabetes Care, vol. 30, pp. 2945 - 2950, http://dx.doi.org/10.2337/dc07-0768

Barter PJ; Puranik R; Rye KA, 2007, 'New insights into the role of HDL as an anti-inflammatory agent in the prevention of cardiovascular disease', Current Cardiology Reports, vol. 9, pp. 493 - 498, http://dx.doi.org/10.1007/BF02938394

Skropeta D; Settasatian C; McMahon MR; Shearston K; Caiazza D; McGrath KC; Jin W; Rader DJ; Barter PJ; Rye KA, 2007, 'N-Glycosylation regulates endothelial lipase-mediated phospholipid hydrolysis in apoE- and apoA-I-containing high density lipoproteins', Journal of Lipid Research, vol. 48, pp. 2047 - 2057, http://dx.doi.org/10.1194/jlr.M700248-JLR200

Matsuo Y; Miura SI; Kawamura A; Uehara Y; Rye KA; Saku K, 2007, 'Newly developed reconstituted high-density lipoprotein containing sphingosine-1-phosphate induces endothelial tube formation', Atherosclerosis, vol. 194, pp. 159 - 168, http://dx.doi.org/10.1016/j.atherosclerosis.2006.10.020

Ooi EMM; Chan DC; Rye KA; Watts GF, 2007, 'Differences in plasma PLTP activity assays: Constant or random error? [2]', Clinical Endocrinology, vol. 67, pp. 317, http://dx.doi.org/10.1111/j.1365-2265.2007.02867.x

Zhang B; Uehara Y; Hida S; Miura SI; Rainwater DL; Segawa M; Kumagai K; Rye KA; Saku K, 2007, 'Effects of reconstituted HDL on charge-based LDL subfractions as characterized by capillary isotachophoresis', Journal of Lipid Research, vol. 48, pp. 1175 - 1189, http://dx.doi.org/10.1194/jlr.M600227-JLR200

Sumi M; Sata M; Miura SI; Rye KA; Toya N; Kanaoka Y; Yanaga K; Ohki T; Saku K; Nagai R, 2007, 'Reconstituted high-density lipoprotein stimulates differentiation of endothelial progenitor cells and enhances ischemia-induced angiogenesis', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 27, pp. 813 - 818, http://dx.doi.org/10.1161/01.ATV.0000259299.38843.64

Nobecourt E; Davies MJ; Brown BE; Curtiss LK; Bonnet DJ; Charlton F; Januszewski AS; Jenkins AJ; Barter PJ; Rye KA, 2007, 'The impact of glycation on apolipoprotein A-I structure and its ability to activate lecithin:cholesterol acyltransferase', Diabetologia, vol. 50, pp. 643 - 653, http://dx.doi.org/10.1007/s00125-006-0574-z

Watts GF; Ji J; Chan DC; Ooi EMM; Johnson AG; Rye KA; Barrett PHR, 2007, 'Erratum: Relationships between changes in plasma lipid transfer proteins and apolipoprotein B-100 kinetics during fenofibrate treatment in the metabolic syndrome (Clinical Science (2006) 111, (193-199))', Clinical Science, vol. 112, pp. 625, http://dx.doi.org/10.1042/cs1120625

Kim WS; Rahmanto A; Kamili A; Rye K; Guillemin GJ; Gelissen I; Jessup W; Hill A; Garner B, 2007, 'Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation', The Journal of Biological Chemistry, vol. 282, pp. 2851 - 2861, http://dx.doi.org/10.1074/jbc.M607831200

Glaros EN; Kim WS; Wu BJ; Suarna C; Quinn CM; Rye K; Stocker R; Jessup W; Garner B, 2007, 'Inhibition of atherosclerosis by the serine palmitoyl transferase inhibitor myriocin is associated with reduced plasma glycosphingolipid concentration', Biochemical Pharmacology, vol. 73, pp. 1340 - 1346, http://dx.doi.org/10.1016/j.bcp.2006.12.023

Ooi EMM; Watts GF; Ji J; Rye KA; Johnson AG; Chan DC; Barrett PHR, 2006, 'Plasma phospholipid transfer protein activity, a determinant of HDL kinetics in vivo', Clinical Endocrinology, vol. 65, pp. 752 - 759, http://dx.doi.org/10.1111/j.1365-2265.2006.02662.x

Zhang B; Katafuchi R; Arishima H; Matsunaga A; Rye KA; Saku K, 2006, 'Effects of atorvastatin and apoA-I/phosphatidylcholine discs on triglyceride-rich lipoprotein subfractions as characterized by capillary isotachophoresis', Clinica Chimica Acta, vol. 373, pp. 55 - 61, http://dx.doi.org/10.1016/j.cca.2006.04.026

Gotto AM; Barter PJ; Rye KA, 2006, 'Over-the-counter statins are worth considering in primary prevention of cardiovascular disease', Circulation, vol. 114, pp. 1310 - 1314, http://dx.doi.org/10.1161/CIRCULATIONAHA.105.552257

Barter PJ; Rye KA, 2006, 'Homocysteine and cardiovascular disease: Is HDL the link?', Circulation Research, vol. 99, pp. 565 - 566, http://dx.doi.org/10.1161/01.RES.0000243583.39694.1f

Barter PJ; Rye KA; Gotto AM, 2006, 'The argument against the appropriateness of over-the-counter statins', Circulation, vol. 114, pp. 1315 - 1320, http://dx.doi.org/10.1161/CIRCULATIONAHA.105.604991

Zhang B; Miura SI; Fan P; Kumagai K; Takeuchi K; Uehara Y; McMahon M; Rye KA; Saku K, 2006, 'ApoA-I/phosphatidylcholine discs remodels fast-migrating HDL into slow-migrating HDL as characterized by capillary isotachophoresis', Atherosclerosis, vol. 188, pp. 95 - 101, http://dx.doi.org/10.1016/j.atherosclerosis.2005.10.032

Watts GF; Ji J; Chan DC; Ooi EMM; Johnson AG; Rye KA; Barrett PHR, 2006, 'Relationships between changes in plasma lipid transfer proteins and apolipoprotein B-100 kinetics during fenofibrate treatment in the metabolic syndrome', Clinical Science, vol. 111, pp. 193 - 199, http://dx.doi.org/10.1042/CS20060072

Nicholls SJ; Lundman P; Harmer JA; Cutri B; Griffiths KA; Rye KA; Barter PJ; Celermajer DS, 2006, 'Consumption of Saturated Fat Impairs the Anti-Inflammatory Properties of High-Density Lipoproteins and Endothelial Function', Journal of the American College of Cardiology, vol. 48, pp. 715 - 720, http://dx.doi.org/10.1016/j.jacc.2006.04.080

Barter PJ; Rye KA, 2006, 'Relationship between the concentration and antiatherogenic activity of high-density lipoproteins', Current Opinion in Lipidology, vol. 17, pp. 399 - 403, http://dx.doi.org/10.1097/01.mol.0000236365.40969.af

Barter P; Rye KA, 2006, 'Are we lowering LDL cholesterol sufficiently?', Nature Clinical Practice Cardiovascular Medicine, vol. 3, pp. 290 - 291, http://dx.doi.org/10.1038/ncpcardio0555

Tso C; Martinic G; Fan WH; Rogers C; Rye KA; Barter PJ, 2006, 'High-density lipoproteins enhance progenitor-mediated endothelium repair in mice', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, pp. 1144 - 1149, http://dx.doi.org/10.1161/01.ATV.0000216600.37436.cf

Rye KA; Bright R; Psaltis M; Barter PJ, 2006, 'Regulation of reconstituted high density lipoprotein structure and remodeling by apolipoprotein E', Journal of Lipid Research, vol. 47, pp. 1025 - 1036, http://dx.doi.org/10.1194/jlr.M500525-JLR200

Kee P; Caiazza D; Rye KA; Barrett PHR; Morehouse LA; Barter PJ, 2006, 'Effect of inhibiting cholesteryl ester transfer protein on the kinetics of high-density lipoprotein cholesteryl ester transport in plasma: In vivo studies in rabbits', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, pp. 884 - 890, http://dx.doi.org/10.1161/01.ATV.0000201064.89581.35

Ji J; Watts GF; Johnson AG; Chan DC; Ooi EMM; Rye KA; Serone AP; Barrett PHR, 2006, 'High-density lipoprotein (HDL) transport in the metabolic syndrome: Application of a new model for HDL particle kinetics', Journal of Clinical Endocrinology and Metabolism, vol. 91, pp. 973 - 979, http://dx.doi.org/10.1210/jc.2005-1895

Barter PJ; Rye KA, 2006, 'Cardioprotective properties of fibrates: Which fibrate, which patients, what mechanism?', Circulation, vol. 113, pp. 1553 - 1555, http://dx.doi.org/10.1161/CIRCULATIONAHA.105.620450

Curtiss LK; Valenta DT; Hime NJ; Rye KA, 2006, 'What is so special about apolipoprotein AI in reverse cholesterol transport?', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, pp. 12 - 19, http://dx.doi.org/10.1161/01.ATV.0000194291.94269.5a

Hime NJ; Drew KJ; Wee K; Barter PJ; Rye KA, 2006, 'Formation of high density lipoproteins containing both apolipoprotein A-I and A-II in the rabbit', Journal of Lipid Research, vol. 47, pp. 115 - 122, http://dx.doi.org/10.1194/jlr.M500284-JLR200

Rentero C; Tebar F; de Muga S; Cubells L; de Diego M; Hayes T; Hughes WE; Pol A; Rye K; Enrich C; Grewal T; Wood P; Evans R, 2006, 'Inhibition of H-Ras and MAPK is compensated by PKC-dependent pathways in annexin A6 expressing cells', Cellular Signalling, vol. 18, pp. 1006 - 1016, http://dx.doi.org/10.1016/j.cellsig.2005.08.008

Jessup W; Gelissen I; Kritharides L; Quinn CM; Kockx M; Brown AJ; Rye K; Harris M; Packianathan M; Cartland SP, 2006, 'ABCA1 and ABCG1 Synergize to Mediate Cholesterol Export to ApoA-I', Arteriosclerosis, Thrombosis and Vascular Biology, vol. 26, pp. 534 - 540, http://dx.doi.org/10.1161/01.ATV.0000200082.58536.e1

Jahangiri A; Rader DJ; Marchadier D; Curtiss LK; Bonnet DJ; Rye KA, 2005, 'Evidence that endothelial lipase remodels high density lipoproteins without mediating the dissociation of apolipoprotein A-I', Journal of Lipid Research, vol. 46, pp. 896 - 903, http://dx.doi.org/10.1194/jlr.M400212-JLR200

Nicholls SJ; Cutri B; Worthley SG; Kee P; Rye KA; Bao S; Barter PJ, 2005, 'Impact of short-term administration of high-density lipoproteins and atorvastatin on atherosclerosis in rabbits', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 25, pp. 2416 - 2421, http://dx.doi.org/10.1161/01.ATV.0000184760.95957.d6

Jänis MT; Metso J; Lankinen H; Strandin T; Olkkonen VM; Rye KA; Jauhiainen M; Ehnholm C, 2005, 'Apolipoprotein E activates the low-activity form of human phospholipid transfer protein', Biochemical and Biophysical Research Communications, vol. 331, pp. 333 - 340, http://dx.doi.org/10.1016/j.bbrc.2005.03.164

Nicholls SJ; Dusting GJ; Cutri B; Bao S; Drummond GR; Rye KA; Barter PJ, 2005, 'Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbits', Circulation, vol. 111, pp. 1543 - 1550, http://dx.doi.org/10.1161/01.CIR.0000159351.95399.50

Nicholls SJ; Rye KA; Barter PJ, 2005, 'High-density lipoproteins as therapeutic targets', Current Opinion in Lipidology, vol. 16, pp. 345 - 349, http://dx.doi.org/10.1097/01.mol.0000169356.58513.25

Grewal T; Evans R; Rentero C; Tebar F; Cubells L; de Diego I; Kirchhoff M; Hughes WE; Heeren J; Rye K; Rinninger F; Daly RJ; Pol A; Enrich C, 2005, 'Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity', Oncogene, vol. 24, pp. 5809 - 5820, http://dx.doi.org/10.1038/sj.onc.1208743

Raftery MJ; Campbell R; Glaros EN; Rye K; Halliday GM; Jessup W; Garner B, 2005, 'Phosphorylation of apolipoprotein-E at an atypical protein kinase CK2 PSD/E site in vitro.', Biochemistry, vol. 44, pp. 7346 - 7353, http://dx.doi.org/10.1021/bi0504052

Gelissen I; Packianathan M; Rye K; Harris ML; Quinn CM; Kritharides L; Jessup W, 2005, 'ABCG1 mediated cholesterol efflux from cells', Atherosclerosis Supplements, vol. 6, pp. 55 - 55, http://dx.doi.org/10.1016/S1567-5688(05)80220-X

Barter PJ; Nicholls S; Rye KA; Anantharamaiah GM; Navab M; Fogelman AM, 2004, 'Antiinflammatory properties of HDL', Circulation Research, vol. 95, pp. 764 - 772, http://dx.doi.org/10.1161/01.RES.0000146094.59640.13

Hime NJ; Drew KJ; Hahn C; Barter PJ; Rye KA, 2004, 'Apolipoprotein E enhances hepatic lipase-mediated hydrolysis of reconstituted high-density lipoprotein phospholipid and triacylglycerol in an isoform-dependent manner', Biochemistry, vol. 43, pp. 12306 - 12314, http://dx.doi.org/10.1021/bi036305i

Caiazza D; Jahangiri A; Rader DJ; Marchadier D; Rye KA, 2004, 'Apolipoproteins regulate the kinetics of endothelial lipase-mediated hydrolysis of phospholipids in reconstituted high-density lipoproteins', Biochemistry, vol. 43, pp. 11898 - 11905, http://dx.doi.org/10.1021/bi049776t

Wadham C; Albanese N; Roberts J; Wang L; Bagley CJ; Gamble JR; Rye KA; Barter PJ; Vadas MA; Xia P, 2004, 'High-Density Lipoproteins Neutralize C-Reactive Protein Proinflammatory Activity', Circulation, vol. 109, pp. 2116 - 2122, http://dx.doi.org/10.1161/01.CIR.0000127419.45975.26

Rye KA; Barter PJ, 2004, 'Formation and Metabolism of Prebeta-Migrating, Lipid-Poor Apolipoprotein A-I', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 24, pp. 421 - 428, http://dx.doi.org/10.1161/01.ATV.0000104029.74961.f5

Kockx M; Rye K; Gaus K; Quinn CM; Wright J; Sloane T; Sviridov D; Fu YL; Sullivan D; Burnett J; Rust S; Assmann G; Anantharamaiah G; Palgunachari M; Katz S; Phillips MA; Dean R; Jessup W; Kritharides L, 2004, 'Apolipoprotein A-I-stimulated apolipoprotein E secretion from human macrophages is independent of cholesterol efflux', The Journal of Biological Chemistry, vol. 279, pp. 25966 - 25977, http://dx.doi.org/10.1074/jbc.M401177200

Heeren J; Grewal T; Laatsch A; Becker NG; Rinninger F; Rye K; Beisiegel U, 2004, 'Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation', The Journal of Biological Chemistry, vol. 279, pp. 55483 - 55492, http://dx.doi.org/10.1074/jbc.M409324200

Duong MN; Psaltis M; Rader DJ; Marchadier D; Barter PJ; Rye KA, 2003, 'Evidence That Hepatic Lipase and Endothelial Lipase Have Different Substrate Specificities for High-Density Lipoprotein Phospholipids', Biochemistry, vol. 42, pp. 13778 - 13785, http://dx.doi.org/10.1021/bi034990n

Rye KA; Wee K; Curtiss LK; Bonnet DJ; Barter PJ, 2003, 'Apolipoprotein A-II inhibits high density lipoprotein remodeling and lipid-poor apolipoprotein A-I formation', Journal of Biological Chemistry, vol. 278, pp. 22530 - 22536, http://dx.doi.org/10.1074/jbc.M213250200

Kee P; Rye KA; Taylor JL; Barrett PHR; Barter PJ, 2002, 'Metabolism of ApoA-I as lipid-free protein or as component of discoidal and spherical reconstituted HDLs: Studies in wild-type and hepatic lipase transgenic rabbits', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 22, pp. 1912 - 1917, http://dx.doi.org/10.1161/01.ATV.0000038485.94020.7F

Barter PJ; Baker PW; Rye KA, 2002, 'Effect of high-density lipoproteins on the expression of adhesion molecules in endothelial cells', Current Opinion in Lipidology, vol. 13, pp. 285 - 288, http://dx.doi.org/10.1097/00041433-200206000-00008

Rye K; Duong M; Psaltis MK; Curtiss LK; Bonnet DJ; Stocker R; Barter P, 2002, 'Evidence that Phospholipids Play a Key Role in Pre-B ApoA-I Formation and High-Density Lipoprotein Remodeling', Biochemistry, vol. 41, pp. 12538 - 12545, http://dx.doi.org/10.1021/bi025998k

Barter PJ; Rye KA, 2001, 'Cholesteryl ester transfer protein, high density lipoprotein and arterial disease', Current Opinion in Lipidology, vol. 12, pp. 377 - 382, http://dx.doi.org/10.1097/00041433-200108000-00002

Settasatian N; Duong MN; Curtiss LK; Ehnholm C; Jauhiainen M; Huuskonen J; Rye KA, 2001, 'The Mechanism of the Remodeling of High Density Lipoproteins by Phospholipid Transfer Protein', Journal of Biological Chemistry, vol. 276, pp. 26898 - 26905, http://dx.doi.org/10.1074/jbc.M010708200

Clay MA; Pyle DH; Rye KA; Vadas MA; Gamble JR; Barter PJ, 2001, 'Time sequence of the inhibition of endothelial adhesion molecule expression by reconstituted high density lipoproteins', Atherosclerosis, vol. 157, pp. 23 - 29, http://dx.doi.org/10.1016/S0021-9150(00)00659-6

Hime NJ; Barter PJ; Rye KA, 2001, 'Evidence that apolipoprotein A-I facilitates hepatic lipase-mediated phospholipid hydrolysis in reconstituted HDL containing apolipoprotein A-II', Biochemistry, vol. 40, pp. 5496 - 5505, http://dx.doi.org/10.1021/bi0016671

Ashby D; Gamble J; Vadas M; Fidge N; Siggins S; Rye KA; Barter PJ, 2001, 'Lack of effect of serum amyloid A (SAA) on the ability of high-density lipoproteins to inhibit endothelial cell adhesion molecule expression', Atherosclerosis, vol. 154, pp. 113 - 121, http://dx.doi.org/10.1016/S0021-9150(00)00437-8

Baker PW; Rye KA; Gamble JR; Vadas MA; Barter PJ, 2000, 'Phospholipid composition of reconstituted high density lipoproteins influences their ability to inhibit endothelial cell adhesion molecule expression', Journal of Lipid Research, vol. 41, pp. 1261 - 1267

Curtiss LK; Bonnet DJ; Rye KA, 2000, 'The conformation of apolipoprotein A-I in high-density lipoproteins is influenced by core lipid composition and particle size: A surface plasmon resonance study', Biochemistry, vol. 39, pp. 5712 - 5721, http://dx.doi.org/10.1021/bi992902m

Clay MA; Pyle DH; Rye KA; Barter PJ, 2000, 'Formation of spherical, reconstituted high density lipoproteins containing both apolipoproteins A-I and A-II is mediated by lecithin:cholesterol acyltransferase', Journal of Biological Chemistry, vol. 275, pp. 9019 - 9025, http://dx.doi.org/10.1074/jbc.275.12.9019

Rye KA; My Ngan Duong , 2000, 'Influence of phospholipid depletion on the size, structure, and remodeling of reconstituted high density lipoproteins', Journal of Lipid Research, vol. 41, pp. 1640 - 1650

Panzenbock U; Kritharides L; Raftery MJ; Rye K; Stocker R, 2000, 'Oxidation of methionine residues to methionine sulfoxides does not decrease potential antiatherogenic properties of apolipoprotein A-I', The Journal of Biological Chemistry, vol. 275, pp. 19536 - 19544, http://dx.doi.org/10.1074/jbc.M000458200

Xia P; Vadas MA; Rye KA; Barter PJ; Gamble JR, 1999, 'High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against a therosclerosis by HDL', Journal of Biological Chemistry, vol. 274, pp. 33143 - 33147, http://dx.doi.org/10.1074/jbc.274.46.33143

Gelissen IC; Rye KA; Brown AJ; Dean RT; Jessup W, 1999, 'Oxysterol efflux from macrophage foam cells: The essential role of acceptor phospholipid', Journal of Lipid Research, vol. 40, pp. 1636 - 1646

Rye KA; Clay MA; Barter PJ, 1999, 'Remodelling of high density lipoproteins by plasma factors', Atherosclerosis, vol. 145, pp. 227 - 238, http://dx.doi.org/10.1016/S0021-9150(99)00150-1

Panzenboeck U; Rye KA; Kritharides L; Stocker R, 1999, 'Selective oxidation of methionine residues enhances rather than decreases potential anti-atherogenic properties of apolipoprotein AI', ATHEROSCLEROSIS, vol. 144, pp. 6 - 6, http://dx.doi.org/10.1016/S0021-9150(99)80017-3

Baker PW; Rye KA; Gamble JR; Vadas MA; Barter PJ, 1999, 'Ability of reconstituted high density lipoproteins to inhibit cytokine- induced expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells', Journal of Lipid Research, vol. 40, pp. 345 - 353

Clay MA; Cehic DA; Pyle DH; Rye KA; Barter PJ, 1999, 'Formation of apolipoprotein-specific high-density lipoprotein particles from lipid-free apolipoproteins A-I and A-II', Biochemical Journal, vol. 337, pp. 445 - 451, http://dx.doi.org/10.1042/0264-6021:3370445

Xia P; Gamble JR; Rye KA; Wang L; Hii CST; Cockerill P; Khew-Goodall Y; Bert AG; Barter PJ; Vadas MA, 1998, 'Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway', Proceedings of the National Academy of Sciences of the United States of America, vol. 95, pp. 14196 - 14201, http://dx.doi.org/10.1073/pnas.95.24.14196

Hime NJ; Barter PJ; Rye KA, 1998, 'The influence of apolipoproteins on the hepatic lipase-mediated hydrolysis of high density lipoprotein phospholipid and triacylglycerol', Journal of Biological Chemistry, vol. 273, pp. 27191 - 27198, http://dx.doi.org/10.1074/jbc.273.42.27191

Garner B; Waldeck AR; Witting PK; Rye KA; Stocker R, 1998, 'Oxidation of high density lipoproteins. II. Evidence for direct reduction of lipid hydroperoxides by methionine residues of apolipoproteins AI and AII', Journal of Biological Chemistry, vol. 273, pp. 6088 - 6095, http://dx.doi.org/10.1074/jbc.273.11.6088

Rye KA; Jauhiainen M; Barter PJ; Ehnholm C, 1998, 'Triglyceride-enrichment of high density lipoproteins enhances their remodelling by phospholipid transfer protein', Journal of Lipid Research, vol. 39, pp. 613 - 622

Ashby DT; Rye KA; Clay MA; Vadas MA; Gamble JR; Barter PJ, 1998, 'Factors influencing the ability of HDL to inhibit expression of vascular cell adhesion molecule-1 in endothelial cells', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 18, pp. 1450 - 1455, http://dx.doi.org/10.1161/01.ATV.18.9.1450

James MJ; Van Reyk D; Rye KA; Dean RT; Cleland LG; Barter PJ; Jessup W, 1998, 'Low density lipoprotein of synovial fluid in inflammatory joint disease is mildly oxidized', Lipids, vol. 33, pp. 1115 - 1121, http://dx.doi.org/10.1007/s11745-998-0313-8

Gelissen IC; Rye KA; Brown AJ; Dean RT; Jessup W, 1997, 'Phospholipid association with apo A-I stimulates oxysterol efflux from macrophage foam cells', ATHEROSCLEROSIS, vol. 134, pp. 367 - 367, http://dx.doi.org/10.1016/S0021-9150(97)89866-8

Rye KA; Hime NJ; Barter PJ, 1997, 'Evidence that cholesteryl ester transfer protein-mediated reductions in reconstituted high density lipoprotein size involve particle fusion', Journal of Biological Chemistry, vol. 272, pp. 3953 - 3960, http://dx.doi.org/10.1074/jbc.272.7.3953

Vadas MA; Gamble JR; Rye K; Barter P, 1997, 'Regulation of leucocyte-endothelial interactions of special relevance to atherogenesis', Clinical and Experimental Pharmacology and Physiology, vol. 24, pp. a33 - a35, http://dx.doi.org/10.1111/j.1440-1681.1997.tb03052.x

Liang HQ; Rye KA; Barter PJ, 1996, 'Remodelling of reconstituted high density lipoproteins by lecithin:cholesterol acyltransferase', Journal of Lipid Research, vol. 37, pp. 1962 - 1979

Rye KA; Hime NJ; Barter PJ, 1996, 'The influence of sphingomyelin on the structure and function of reconstituted high density lipoproteines', Journal of Biological Chemistry, vol. 271, pp. 4243 - 4250, http://dx.doi.org/10.1074/jbc.271.8.4243

Kee P; Bais R; Sobecki SK; Branford S; Rye KA; Barter PJ, 1996, 'Indirect sandwich enzyme-linked immunosorbent assay (ELISA) for plasma apolipoprotein E', Annals of Clinical Biochemistry, vol. 33, pp. 119 - 126, http://dx.doi.org/10.1177/000456329603300204

Contacos C; Sullivan DR; Rye KA; Funke H; Assmann G, 1996, 'A new molecular defect in the lecithin:cholesterol acyltransferase (LCAT) gene associated with fish eye disease', Journal of Lipid Research, vol. 37, pp. 35 - 44

Barter PJ; Rye KA, 1996, 'High density lipoproteins and coronary heart disease', Atherosclerosis, vol. 121, pp. 1 - 12, http://dx.doi.org/10.1016/0021-9150(95)05675-0

Barter PJ; Rye KA, 1996, 'Molecular mechanisms of reverse cholesterol transport', Current Opinion in Lipidology, vol. 7, pp. 82 - 87, http://dx.doi.org/10.1097/00041433-199604000-00006

Liang HQ; Rye KA; Barter PJ, 1995, 'Cycling of apolipoprotein A-I between lipid-associated and lipid-free pools', Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, vol. 1257, pp. 31 - 37, http://dx.doi.org/10.1016/0005-2760(95)00055-H

Rye KA; Hime NJ; Barter PJ, 1995, 'The influence of cholesteryl ester transfer protein on the composition, size, and structure of spherical, reconstituted high density lipoproteins', Journal of Biological Chemistry, vol. 270, pp. 189 - 196, http://dx.doi.org/10.1074/jbc.270.1.189

Christison JK; Rye KA; Stocker R, 1995, 'Exchange of oxidized cholesteryl linoleate between LDL and HDL mediated by cholesteryl ester transfer protein', Journal of Lipid Research, vol. 36, pp. 2017 - 2026

Cockerill GW; Rye KA; Gamble JR; Vadas MA; Barter PJ, 1995, 'High-density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 15, pp. 1987 - 1994, http://dx.doi.org/10.1161/01.ATV.15.11.1987

Barter P; Rye KA, 1994, 'Erratum: Cholesteryl ester transfer protein: Its role in plasma lipid transport (Clinical and Experimental Pharmacology and Physiology, Vol. 21 (663-672))', Clinical and Experimental Pharmacology and Physiology, vol. 21, pp. 933

Rye KA; Barter PJ, 1994, 'The influence of apolipoproteins on the structure and function of spheroidal, reconstituted high density lipoproteins', Journal of Biological Chemistry, vol. 269, pp. 10298 - 10303

Liang HQ; Rye KA; Barter PJ, 1994, 'Dissociation of lipid-free apolipoprotein A-I from high density lipoproteins', Journal of Lipid Research, vol. 35, pp. 1187 - 1199

Barter PJ; Rye KA, 1994, 'High-density lipoproteins and coronary heart disease', European Journal of Cardiovascular Prevention & Rehabilitation, vol. 1, pp. 217 - 221, http://dx.doi.org/10.1177/174182679400100306

Barter P; Rye K, 1994, 'CHOLESTERYL ESTER TRANSFER PROTEIN: ITS ROLE IN PLASMA LIPID TRANSPORT', Clinical and Experimental Pharmacology and Physiology, vol. 21, pp. 663 - 672, http://dx.doi.org/10.1111/j.1440-1681.1994.tb02569.x

Rye KA; Garrety KH; Barter PJ, 1993, 'Preparation and characterization of spheroidal, reconstituted high-density lipoproteins with apolipoprotein A-I only or with apolipoprotein A-I and A-II', Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, vol. 1167, pp. 316 - 325, http://dx.doi.org/10.1016/0005-2760(93)90235-2

Barter PJ; Rajaram OV; Liang HQ; Rye KA, 1993, 'Relationship between the size and phospholipid content of low-density lipoproteins', Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, vol. 1166, pp. 135 - 137, http://dx.doi.org/10.1016/0005-2760(93)90294-J

Rye KA; Garrety KH; Barter PJ, 1992, 'Changes in the size of reconstituted high density lipoproteins during incubation with cholesteryl ester transfer protein: The role of apolipoproteins', Journal of Lipid Research, vol. 33, pp. 215 - 224

Barter PJ; Chang LBF; Newnham HH; Rye KA; Rajaram OV, 1990, 'The interaction of cholesteryl ester transfer protein and unesterified fatty acids promotes a reduction in the particle size of high-density lipoproteins', Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, vol. 1045, pp. 81 - 89, http://dx.doi.org/10.1016/0005-2760(90)90206-D

Clay MA; Rye KA; Barter PJ, 1990, 'Evidence in vitro that hepatic lipase reduces the concentration of apolipoprotein A-I in rabbit high-density lipoproteins', Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, vol. 1044, pp. 50 - 56, http://dx.doi.org/10.1016/0005-2760(90)90217-L

Rye KA, 1990, 'Interaction of apolipoprotein A-II with recombinant HDL containing egg phosphatidylcholine, unesterified cholesterol and apolipoprotein A-I', Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, vol. 1042, pp. 227 - 236, http://dx.doi.org/10.1016/0005-2760(90)90013-N

Rye KA, 1989, 'Interaction of the high density lipoprotein conversion factor with recombinant discoidal complexes of egg phosphatidylcholine, free cholesterol, and apolipoprotein A-I', Journal of Lipid Research, vol. 30, pp. 335 - 346

Jonas A; Kezdy E; Williams MI; Rye KA, 1988, 'Lipid transfers between reconstituted high density lipoprotein complexes and low density lipoproteins: Effects of plasma protein factors', Journal of Lipid Research, vol. 29, pp. 1349 - 1357

Barter PJ; Rajaram OV; Chang LBF; Rye KA; Gambert P; Lagrost L; Ehnholm C; Fidge NH, 1988, 'Isolation of a high-density-lipoprotein conversion factor from human plasma. A possible role of apoliprotein A-IV as its activator', Biochemical Journal, vol. 254, pp. 179 - 184, http://dx.doi.org/10.1042/bj2540179

Rye KA; Barter PJ, 1986, 'Changes in the size and density of human high-density lipoproteins promoted by a plasma-conversion factor', Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, vol. 875, pp. 429 - 438, http://dx.doi.org/10.1016/0005-2760(86)90062-7

Rye KA; Barter PJ, 1984, 'Evidence of the existence of a high-density lipoprotein transformation factor in pig and rabbit plasma', Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, vol. 795, pp. 230 - 237, http://dx.doi.org/10.1016/0005-2760(84)90070-5

Beckwith PLM; Fornasiero D; Horr T; Rye KA; Kurucsev T, 1984, 'POLYMER HEAT ENGINES: 1. STUDY OF POLY(VINYLAMINE) AND SOME OF ITS DERIVATIVES AS POTENTIAL WORKING SUBSTANCES IN HEAT ENGINES.', Polymer Communications (Guildford, England), vol. 25, pp. 18 - 20

Hughes BP; Rye KA; Pickford LB, 1984, 'A transient increase in diacylglycerols is associated with the action of vasopressin on hepatocytes', Biochemical Journal, vol. 222, pp. 535 - 540, http://dx.doi.org/10.1042/bj2220535

Fornasiero D; Rons IAG; Rye KA; Kurucsev T, 1981, 'Near-Ultraviolet Vibronic Transitions of Adenosine 5'-Phosphate, Adenosine, and Its Complexes with cis- and trans-Diamminedichloroplatinum(II): Spectral Study of Isotropic Absorption, Linear Dichroism, and Circular Dichroism', Journal of the American Chemical Society, vol. 103, pp. 1908 - 1913, http://dx.doi.org/10.1021/ja00398a006

Krus S; Domaniewski J; Rye K, 1971, 'Relationship between the intensity of atherosclerosis and histological appearance of testicles.', Polish medical science and history bulletin, vol. 14, pp. 83 - 85

Conference Papers

Weise CB; Toth CL; Landstreet SR; Taylor RC; Tabet F; Rye KA; Hofmeister LH; Harrison DG; Kon V; Vickers K, 2014, 'NOVEL HDL FUNCTIONS ASSOCIATED WITH INTERCELLULAR COMMUNICATION, ATHEROSCLEROSIS, AND CHRONIC KIDNEY DISEASE', in ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, Spanish Soc Atherosclerosis, Madrid, SPAIN, pp. E22 - E22, presented at 82nd Congress of the European-Atherosclerosis-Society (EAS), Spanish Soc Atherosclerosis, Madrid, SPAIN, 31 May 2014 - 03 June 2014, http://dx.doi.org/10.1016/j.atherosclerosis.2014.05.032

Tabet F; Vickers KC; Torres LFC; Ammori B; Yadav R; Hama S; Liu Y; Schofield J; Barter P; Soran H; Rye KA, 2014, 'EFFECT OF BARIATRIC SURGERY ON HDL-ASSOCIATED MICRORNAS', in ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, Spanish Soc Atherosclerosis, Madrid, SPAIN, pp. E32 - E33, presented at 82nd Congress of the European-Atherosclerosis-Society (EAS), Spanish Soc Atherosclerosis, Madrid, SPAIN, 31 May 2014 - 03 June 2014, http://dx.doi.org/10.1016/j.atherosclerosis.2014.05.065

Tabet F; Lee S; Torres CL; Levin M; Drummond GR; Remaley A; Rye KA; Vickers K; Sobey CG, 2013, 'TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL CIRCUITRY IN THE BRAIN AFTER TRANSIENT AND PERMANENT ISCHEMIA', in HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Melbourne, AUSTRALIA, pp. E157 - E158, presented at 35th Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia (HBPRCA) / 39th Annual Scientific Meeting of the Australian-Atherosclerosis-Society (AAS), Melbourne, AUSTRALIA, 05 December 2013 - 07 December 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335491900076&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Bisoendial R; Roediger B; Jain R; Cavanagh L; Tak P-P; Rye K-A; Weninger W, 2013, 'TARGETING LYMPHATIC DYSFUNCTION IN RHEUMATOID ARTHRITIS BY HIGH-DENSITY LIPOPROTEIN', in ANNALS OF THE RHEUMATIC DISEASES, BMJ PUBLISHING GROUP, pp. 195 - 195, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000331587902015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Charlton F; Xu B; Makris A; Rye K; Hennessy A, 2011, 'Protective effects of high density lipoproteins in a model of pre-eclampsia', in Placenta, W B Saunders Company Ltd, London, England, pp. A94 - A94, presented at Meeting of the International-Federation-of-Placenta-Associations (IFPA), Geilo NORWAY, 14 September 2011 - 17 September 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295072200212&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Charlton F; Xu B; Makris A; Rye K; Hennessy A, 2011, 'High density lipoproteins restore integrin switching in a model of pre-eclampsia', in Placenta, W B Saunders Company Ltd, London, England, pp. A94 - A94, presented at Meeting of the International-Federation-of-Placenta-Associations (IFPA), Geilo NORWAY, 14 September 2011 - 17 September 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295072200213&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Fryirs MA; Barter PJ; Appavoo M; Tuch B; Tabet F; Heater AK; Rye KA, 2009, 'High Density Lipoproteins Increase the Insulin Secretory Capacity of Pancreatic beta-Cells', in DIABETES, AMER DIABETES ASSOC, New Orleans, LA, pp. A426 - A426, presented at 69th Annual Meeting of the American-Diabetes-Association, New Orleans, LA, 05 June 2009 - 09 June 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000266352602394&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Gelissen I; Harris M; Rye KA; Quinn CM; Brown AJ; Kockx M; Cartland S; Packianathan M; Kritharides L; Jessup W, 2006, 'ABCA1 and ABCG1 act sequentially to mediate cholesterol export to apoA-I', in ATHEROSCLEROSIS SUPPLEMENTS, ELSEVIER IRELAND LTD, Rome, ITALY, pp. 541 - 541, presented at 14th Meeting of the International-Society-of-Atherosclerosis, Rome, ITALY, 18 June 2006 - 22 June 2006, http://dx.doi.org/10.1016/S1567-5688(06)82178-1

Taylor J; Rye KA; Sloane T; Gaus K; Ruberu K; Jessup W; Kritharides L, 2006, 'Exogenous apolipoprotein A-I promotes faecal sterol excretion in hypercholesterolemic rabbits', in ATHEROSCLEROSIS SUPPLEMENTS, ELSEVIER IRELAND LTD, Rome, ITALY, pp. 167 - 167, presented at 14th Meeting of the International-Society-of-Atherosclerosis, Rome, ITALY, 18 June 2006 - 22 June 2006, http://dx.doi.org/10.1016/S1567-5688(06)80653-7

Barter PJ; Rye KA, 2006, 'The rationale for using apoA-I as a clinical marker of cardiovascular risk', in Journal of Internal Medicine, pp. 447 - 454, http://dx.doi.org/10.1111/j.1365-2796.2006.01647.x

Barter PJ; Chang LBF; Newnham HH; Rye KA; Rajaram OV, 1990, 'Roles of lecithin: Cholesterol acyltransferase, lipid transfer proteins and nonesterified fatty acids in plasma cholesterol transport', in Journal of Drug Development, Supplement, pp. 85 - 89

Conference Presentations

Manandhar B; Cochran BJ; Rye K, 2019, 'APOLIPOPROTEIN A-I LOCALISES TO MITOCHONDRIA AND INHIBITS ROS GENERATION IN INSULIN PRODUCING CELLS.', Victoria University City Convention Centre, Melbourne, presented at AAS 2019 Annual Scientific meeting, Victoria University City Convention Centre, Melbourne, 16 October 2019 - 19 October 2019

Tucker B; Rehan R; Vaidya K; Rye K; Cochran B; Patel S, 2019, 'Colchicine inhibits neutrophil extracellular trap formation in acute coronary syndrome patients', Melbourne, presented at Australian Atherosclerosis Society Annual Scientific Meeting, Melbourne, 16 October 2019 - 19 October 2019

Tan WT; Kopecky C; Manandhar B; Rye K-A; Cochran B, 2019, 'Skeletal Muscle Specific Deletion Of Abca1 And Abcg1 Impacts Body Composition And Metabolism And Is Age Dependent', presented at 87th European Atherosclerosis Society Congress, 26 May 2019, http://dx.doi.org/10.1016/j.atherosclerosis.2019.06.122

Conference Abstracts

Ong KL; McClelland R; Allison MA; Cushman M; Garg P; Tsai MY; Rye KA; Tabet F, 2020, 'Association of Lipoprotein (a) and Coronary Artery Calcification: Prospective Study Assessing Interactions With Other Risk Factors in the Multi-Ethnic Study of Atherosclerosis', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 142, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000607190400133&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ong KL; O'Connell R; Januszewski AS; Jenkins AJ; Xu A; Sullivan DR; Barter PJ; Scott RS; Taskinen MR; Waldman B; Colman PG; Best JD; Simes JR; Rye KA; Keech AC, 2017, 'Baseline Circulating FGF-21 Levels and Increase after Fenofibrate Treatment Predict More Rapid Glycemic Progression in Type 2 Diabetes: Results from the FIELD Study', in DIABETES, AMER DIABETES ASSOC, San Diego, CA, Vol. 66, pp. A458 - A458, presented at 77th Scientific Sessions of the American-Diabetes-Association, San Diego, CA, 09 June 2017 - 13 June 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000408064103220&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Wu BJ; Sun Y; Tang S; Ong KL; Barter PJ; Rye K, 2017, 'Apolipoprotein A-I Protects against Pregnancy-Induced Insulin Resistance in Rats', in DIABETES, AMER DIABETES ASSOC, San Diego, CA, Vol. 66, pp. A32 - A32, presented at 77th Scientific Sessions of the American-Diabetes-Association, San Diego, CA, 09 June 2017 - 13 June 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000408064100126&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Cochran BJ; Hou L; Manavalan APC; Sultana A; Moore BM; Patel M; Tall A; Barter PJ; Rye KA, 2015, 'PANCREATIC BETA-CELL SPECIFIC DELETION OF ABCA1 AND ABCG1 PERTURBS GLUCOSE METABOLISM AND INCREASES ADIPOSITY IN MICE DUE TO SUBOPTIMAL PLASMA INSULIN LEVELS', in ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, Glasgow, SCOTLAND, Vol. 241, pp. E3 - E3, presented at 83rd Congress of the European-Atherosclerosis-Society (EAS), Glasgow, SCOTLAND, 22 March 2015 - 25 March 2015, http://dx.doi.org/10.1016/j.atherosclerosis.2015.04.028

Ong KL; Rye K-A; O'Connell R; Jenkins AJ; Brown C; Xu A; Sullivan DR; Barter PJ; Keech AC, 2012, 'Long-term Fenofibrate Therapy Increases Fibroblast Growth Factor 21 and Retinol-binding Protein 4 in Subjects With Type 2 Diabetes', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 126, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208885001409&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Mechanisms of Disease and Translational Research