SoMS Honours

SoMS Honours

Potential Projects » Cellular & Systems Physiology

 

Academic Project Title

Prof Diane Fatkin & Dr Inken Martin

Victor Chang Cardiac Research Institute

Investigating gene-environment interactions in inherited heart disease using zebrafish models

Prof Robert M Graham and Dr Xenia Kaidonis

Victor Chang Cardiac Research Institute

Elucidating the cardioprotective role of the α1A adrenergic receptor

Prof Rob Herbert

Neuroscience Research Australia

Using diffusion tensor imaging to reconstruct the 3D architecture of human muscles in vivo

Dr Adam Hill

Victor Chang Cardiac Research Institute

Using stem cell derived myocytes to investigate drug induced cardiac arrhythmias

A/Prof Megan Lord & Prof John Whitelock

Graduate School of Biomedical Engineering

Development of hyaluronan-based scaffolds for tissue engineering - This project aims to mimic the naturally occurring hyaluronan crosslinking mechanisms in tissues to build next generation biomimetic hyaluronan-based tissue engineering scaffolds

Dr Damia Mawad & Dr Kate Poole

School of Materials Science and Engineering & SoMS

Flexible and soft optoelectronics device to interface with neural cells: an interdisciplinary approach to remotely control cell behaviour

Prof Peter Macdonald & Dr Jeanette Villanueva

Victor Chang Cardiac Research Institute

Development of an in vitro donor heart preservation model to test the cardioprotective effects of novel sodium-hydrogen exchanger inhibitors

A/Prof Andrew Moorhouse

Neurobiology Research Lab, SoMS

Plasticity of inhibitory synaptic transmission in disease. Our current focus is developing better therapies to treat drug resistant epilepsy by targeting KCC2 membrane transporters and GABA receptors.

Dr Tim Murphy

Cardiovascular Disease Group, SoMS

Resistance artery function in health and disease

Dr Kate Poole

Cellular Mechanotransduction, Single Molecular Science, SoMS

A cellular sense of touch: force-sensing ion channels
 
Graduate School of Biomedical Engineering
 
Vascular supply in bioengineered tissues - This project aims to understand the physical and biological cues that drive tissue vascularisation and replicate them in bioengineered tissues
 
Graduate School of Biomedical Engineering
 
Biomaterial-directed vascularisation of bioengineered cardiac patches - this project aims to develop novel biomaterials that support vascular regeneration and therefore extend the utility of cardiac patches for the treatment of heart damage following myocardial infarction.

Prof Kerry-Anne Rye

Lipid Research Group, SoMS

Using small mimetic peptides to prevent diabetes and heart disease

Prof Kerry-Anne Rye

Lipid Research Group, SoMS

The cardioprotective and anti-diabetic properties of the HDL apolipoprotein, apoA-IV 

Prof Kerry-Anne Rye

Lipid Research Group, SoMS

The role of fibroblast growth factor 21 in atherosclerosis and cardiovascular disease risk

Prof Kerry-Anne Rye

Lipid Research Group, SoMS

Regulation of cardiovascular disease by the miRNA cargo of HDL 

Prof Roland Stocker

Victor Chang Cardiac Research Institute

Molecular mechanisms of arterial relaxation and blood pressure control in systemic inflammation

Prof Roland Stocker

Victor Chang Cardiac Research Institute

Development of new non-invasive imaging technology for the identification of atherosclerotic plaques that can cause an acute myocardial infarct

Prof Roland Stocker

Victor Chang Cardiac Research Institute

Metabolome difference between unstable and stable atherosclerotic plaque

Prof Melissa Knothe Tate

Graduate School of Biomedical Engineering

Cellular Connectivity as a Marker of Degenerative Bone Disease 

Prof Jamie Vandenberg & Dr Matt Perry

Victor Chang Cardiac Research Institute

High-throughput phenotyping of induced pluripotent stem cell cardiomyocytes to quantify genetic and environmental modifiers of pro-arrhythmic risk

Prof Jamie Vandenberg & Dr Chai Ng

Victor Chang Cardiac Research Institute

Determining the probability of pathogenicity of all missense variants in KCNH2, the genetic basis of congenital long QT syndrome type 2