SoMS Honours

Potential Projects » Cancer

Academic	Project Title
Prof Minoti Apte & Prof Jeremy Wilson SWS Clinical School and Ingham Institute for Applied Medical Research	Novel therapeutic approaches for pancreatic cancer – characterising and targeting stromal-tumour interactions
A/Prof Therese Becker Centre for Circulating Tumor Cell Diagnostics & Research, Ingham Institute for Applied Medical Research	Liquid biopsies for the detection of clinically relevant biomarkers in brain cancer
Dr Annemiek Beverdam Developmental and Regenerative Dermatology Unit, SoMS	Role of YAP in skin stem cell development and regeneration and in skin cancer
A/Prof Till Boecking & Prof Peter Gunning Single Molecule Science & Cellular and Genetic Medicine Unit, SoMS	Assembly mechanisms of cancer-associated actin filaments
Prof Peter Gunning Cellular and Genetic Medicine Unit, SoMS	Molecular mechanisms of a novel class of cytoskeleton targeted anti-cancer compounds
Dr Liz Caldon Garvan Institute of Medical Research	DNA damage in hormone resistant breast cancer
Dr Liz Caldon Garvan Institute of Medical Research	Quantitative analysis of genome stability in human tumour samples
Dr Christine Chaffer & Dr David Gallego Ortega Garvan Institute of Medical Research	Defining the aggressive cancer cells that drive cancer development and metastasis using single-cell genomics
Dr Joanna Achinger-Kawecka Garvan Institute of Medical Research	Uncovering the 3D Genome Architecture in Cancer
Dr Belamy Cheung Children's Cancer Institute	Inhibiting the MYCN oncogenic signal
Dr Belamy Cheung Children's Cancer Institute	Chemical inhibition of ubiquitin-specific proteases for targeting MYCN protein stability
Dr Arcadi Cipponi Garvan Institute of Medical Research	Stress-induced genomic instability as a driver of adaptive responses in human cancer cells
Dr Thomas Cox Garvan Institute of Medical Research	Understanding the role of the extracellular matrix in cancer progression
Dr David Croucher Garvan Institute of Medical Research	Modelling tumour adaptation with single-cell kinase biosensors
Prof Peter Croucher Garvan Institute of Medical Research	ProMis: Prostate cancer metastasis Transcriptional profiling of dormant prostate cancer cells in the skeleton
Dr Michael Jameson & Dr Joanne Toohey St Vincent’s Clinical School, Radiation Oncology	MRI guided cardiac radio-ablation for end stage ventricular tachycardia
Dr Michael Jameson & Dr Jeremy de Leon St Vincent’s Clinical School, Radiation Oncology	Personalised adaptive radiotherapy delivered with a magnetic resonance imaging guided linear accelerator
Dr Caroline Ford Adult Cancer Program	Novel receptors in ovarian cancer: potential targets for personalised medicine?
Dr Caroline Ford Adult Cancer Program	The role of Wnt signalling in aggressive endometrial cancer
Dr David Gallego Ortega Garvan Institute of Medical Research	Development of immunotherapies for breast cancer
Prof Edna Hardeman & Prof Peter Gunning Cellular and Genetic Medicine Unit, SoMS	Visualising the impact of anti-cancer drugs on cell dynamics in vivo
Dr Michelle Henderson Children's Cancer Institute	Identification and characterization of novel MLL inhibitors
A/Prof Jeff Holst Translational Cancer Metabolism Laboratory, SoMS & POW Clinical School	Developing new therapies targeting cancer metabolism in melanoma, prostate and breast cancer
A/Prof Phoebe Phillips Adult Cancer Program & SoMS	Disrupting the epigenetic core machinery in pancreatic cancer stem cells for induction of long-lasting tumour remission
Prof David Goldstein Prince of Wales Clinical School	(Epi-)Genetic profiling of circulating cancer (stem) cells in patients with metastatic pancreatic ductal adenocarcinoma
Dr Xiao-Tao Jiang & Dr Howard Yim Microbiome Research Centre, St George and Sutherland Clinical School	The role of enteric virome in colon cancer
Dr MoonSun Jung & Dr Caroline Atkinson Children's Cancer Institute	Developing mouse models for high-risk neuroblastoma metastasis using bioluminescent patient-derived xenograft (PDX) cells
Dr Nadeem Kaakoush Cancer Institute NSW Fellow, SoMS	Examining the role of the oesophageal microbiome in the oesophageal adenocarcinoma cascade
Dr Alvin Kamili & Dr Jamie Fletcher Children's Cancer Institute	Pre-clinical modelling of new therapies for high-risk neuroblastoma
Dr Alvin Kamili & Dr Ruby Pandher Children's Cancer Institute	Lipidomic profiling of high-risk neuroblastoma for the identification of novel biomarkers and therapeutic targets
Dr Alvin Kamili, Dr Caroline Atkinson & Dr Jamie Fletcher Children's Cancer Institute	Targeting BCL-2 family proteins in high-risk neuroblastoma
Dr Maya Kansara & Prof David Thomas Garvan Institute of Medical Research	Investigation of conventional chemotherapy and immunomodulatory strategies in bone cancer
Dr Maya Kansara & Prof David Thomas Garvan Institute of Medical Research	Targeting immune checkpoint blockers in bone cancer
A/Prof Maija Kohonen-Corish Microbiome Research Centre, St George and Sutherland Clinical School	Role of the microbiome in lung cancer and its treatment.
A/Prof Yong Li & Dr Kevin Ni St George & Sutherland Clinical School	Exosomal miRNAs in prostate cancer radioresistance
A/Prof Elgene Lim & Dr Alex Swarbrick Garvan Institute of Medical Research	IL6/JAK/STAT as novel targets in breast cancer
A/Prof Elgene Lim & Dr Alex Swarbrick Garvan Institute of Medical Research	New targeted therapeutic strategies for chemo-resistant breast cancers
Dr Johnson Liu Department of Pharmacology, SoMS	Targeting Wnt signalling pathways in colorectal cancer
Dr Tao Liu Children's Cancer Institute	The critical roles of long noncoding RNAs in tumourigenesis and as targets for cancer therapy
Dr Tao Liu Children's Cancer Institute	Enhancing the anticancer efficacy of transcriptional super-enhancer inhibitors
Prof Richard Lock & Dr Cara Toscan Children’s Cancer Institute	Mechanisms of AKR1C3 gene expression in paediatric acute lymphoblastic leukaemia with respect to sensitivity to the AKR1C3-activated prodrug OBI-3424
Dr Karen MacKenzie & Dr Toby Trahair Children's Cancer Institute	Discovery and testing of new treatments for paediatric inflammatory myofibroblastic tumours
Dr Karen MacKenzie Children's Cancer Institute	Targeting telomerase components in paediatric cancer
Dr Angelica Merlot & Prof Maria Kavallaris Children's Cancer Institute	Dissecting the role of endoplasmic reticulum stress in cancer cell progression and metastasis in the tumour microenvironment
Dr Angelica Merlot & Prof Maria Kavallaris Children's Cancer Institute	Developing albumin-based nanoparticles that overcome drug resistance and metastasis
A/Prof Ewan Millar & Dr Julia Beretov St George & Sutherland Clinical School	Proteomic approaches in biomarker development for breast cancer
Dr Tim Molloy Garvan Institute of Medical Research	Micro-RNA regulators of radiotherapy resistance in breast cancer
Dr Max Nobis & A/Prof Paul Timpson Garvan Institute of Medical Research	Using in vivo imaging to target DNA damage response and PI3K signalling in pancreatic cancer
Dr Marina Pajic, Ms Ashleigh Parkin & A/Prof Ruta Gupta Garvan Institute of Medical Research	Development of tailored treatment approaches for head and neck squamous cell carcinoma
Dr Tri Phan & Dr Akira Nguyen Garvan Institute of Medical Research	The role of subcapsular sinus (SCS) macrophages in LN melanoma metastases
A/Prof Patsie Polly & Dr Timothy Tan Cancer Cachexia Mechanisms Research Group, SoMS	Transcriptional regulation of muscle wasting in cancer
Dr Kate Poole Single Molecule Science, SoMS	How do force-sensing ion channels influence melanoma migration?
Dr Prashanth J Rao Prince of Wales Clinical School	Role of nanoparticles in treatment of brain tumours (Collaboration with Lowy cancer institute, School of Materials Science & Engineering and Faculty of Engineering UNSW)
Dr Prashanth J Rao Prince of Wales Clinical School	Evaluation of prognosis of diffuse glioma based on molecular markers
Dr Joanne Reed Garvan Institute of Medical Research	Using genomic technology to study the rogue cells that cause autoimmune disease and cancer
Prof Nicholas Shackel SWS Clinical School and Ingham Institute for Applied Medical Research	Circulating tumour cells in liver cancer: Personalised cancer diagnosis and management
Prof Nicholas Shackel SWS Clinical School and Ingham Institute for Applied Medical Research	Understanding the genetic diversity of liver cancer: A hallmark of cancer risk and behavior (Honours & MSc)
Prof Nicholas Shackel SWS Clinical School and Ingham Institute for Applied Medical Research	Novel antibody and siRNA mediated therapy in liver cancer (Honours & MSc)
Dr Julie Thoms, Dr Dominik Beck & Prof John Pimanda Adult Cancer Program & SoMS	Characterisation of lincRNAs that predict patient outcome in AML
Dr Julie Thoms & Prof John Pimanda Adult Cancer Program & SoMS	The role of stem cell enhancers in normal and leukaemic blood development
A/Prof Nigel Turner Mitochondrial Bioenergetics Group, SoMS	How is cellular energy metabolism altered in cancer?
Dr Vinod Vijay Subhash, Dr Jamie Fletcher & Dr Toby Trahair Children's Cancer Institute	The role of tumour-derived exosomes in dissemination and metastasis of neuroblastoma
Dr Vinod Vijay Subhash, Dr Jamie Fletcher & Dr Toby Trahair Children's Cancer Institute	Cancer stem cells in neuroblastoma chemo resistance and metastasis
Dr Jenny Wang Children's Cancer Institute	Epigenetic regulation of leukaemia stem cells
Dr Jenny Wang Children's Cancer Institute	Developing a new curative therapy for aggressive leukaemia
Dr Lindsay Wu & Prof David Sinclair Molecular Biology of Ageing, SoMS	New drugs to target NAD⁺ and sirtuins in liver cancer
Dr Lindsay Wu & Prof David Sinclair Molecular Biology of Ageing, SoMS	Substrate partitioning and the Warburg effect: why do cancer cells not use oxygen?
A/Prof Amany Zekry & Dr Lan Gong Microbiome Research Centre, St George and Sutherland Clinical School	The role of the microbiome in obesity related liver inflammation and liver cancer