SoMS Honours
Potential Projects » Cancer
Academic | Project Title |
Prof Minoti Apte & Prof Jeremy Wilson SWS Clinical School and Ingham Institute for Applied Medical Research |
Novel therapeutic approaches for pancreatic cancer – characterising and targeting stromal-tumour interactions |
Centre for Circulating Tumor Cell Diagnostics & Research, Ingham Institute for Applied Medical Research |
Liquid biopsies for the detection of clinically relevant biomarkers in brain cancer |
Role of YAP in skin stem cell development and regeneration and in skin cancer | |
A/Prof Till Boecking & Prof Peter Gunning Single Molecule Science & Cellular and Genetic Medicine Unit, SoMS |
Assembly mechanisms of cancer-associated actin filaments |
Molecular mechanisms of a novel class of cytoskeleton targeted anti-cancer compounds | |
Garvan Institute of Medical Research |
DNA damage in hormone resistant breast cancer |
Garvan Institute of Medical Research |
Quantitative analysis of genome stability in human tumour samples |
Dr Christine Chaffer & Dr David Gallego Ortega Garvan Institute of Medical Research |
Defining the aggressive cancer cells that drive cancer development and metastasis using single-cell genomics |
Garvan Institute of Medical Research |
Uncovering the 3D Genome Architecture in Cancer |
Children's Cancer Institute |
Inhibiting the MYCN oncogenic signal |
Children's Cancer Institute |
Chemical inhibition of ubiquitin-specific proteases for targeting MYCN protein stability |
Garvan Institute of Medical Research |
Stress-induced genomic instability as a driver of adaptive responses in human cancer cells |
Garvan Institute of Medical Research |
Understanding the role of the extracellular matrix in cancer progression |
Garvan Institute of Medical Research |
Modelling tumour adaptation with single-cell kinase biosensors |
Garvan Institute of Medical Research |
ProMis: Prostate cancer metastasis
Transcriptional profiling of dormant prostate cancer cells in the skeleton
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Dr Michael Jameson & Dr Joanne Toohey St Vincent’s Clinical School, Radiation Oncology |
MRI guided cardiac radio-ablation for end stage ventricular tachycardia |
Dr Michael Jameson & Dr Jeremy de Leon St Vincent’s Clinical School, Radiation Oncology |
Personalised adaptive radiotherapy delivered with a magnetic resonance imaging guided linear accelerator |
Adult Cancer Program |
Novel receptors in ovarian cancer: potential targets for personalised medicine? |
Adult Cancer Program |
The role of Wnt signalling in aggressive endometrial cancer |
Garvan Institute of Medical Research |
Development of immunotherapies for breast cancer |
Visualising the impact of anti-cancer drugs on cell dynamics in vivo | |
Children's Cancer Institute |
Identification and characterization of novel MLL inhibitors |
Translational Cancer Metabolism Laboratory, SoMS & POW Clinical School |
Developing new therapies targeting cancer metabolism in melanoma, prostate and breast cancer |
Adult Cancer Program & SoMS |
Disrupting the epigenetic core machinery in pancreatic cancer stem cells for induction of long-lasting tumour remission |
Prince of Wales Clinical School |
(Epi-)Genetic profiling of circulating cancer (stem) cells in patients with metastatic pancreatic ductal adenocarcinoma |
Dr Xiao-Tao Jiang & Dr Howard Yim Microbiome Research Centre, St George and Sutherland Clinical School |
The role of enteric virome in colon cancer |
Dr MoonSun Jung & Dr Caroline Atkinson Children's Cancer Institute |
Developing mouse models for high-risk neuroblastoma metastasis using bioluminescent patient-derived xenograft (PDX) cells |
Cancer Institute NSW Fellow, SoMS |
Examining the role of the oesophageal microbiome in the oesophageal adenocarcinoma cascade |
Dr Alvin Kamili & Dr Jamie Fletcher Children's Cancer Institute |
Pre-clinical modelling of new therapies for high-risk neuroblastoma |
Dr Alvin Kamili & Dr Ruby Pandher Children's Cancer Institute |
Lipidomic profiling of high-risk neuroblastoma for the identification of novel biomarkers and therapeutic targets |
Dr Alvin Kamili, Dr Caroline Atkinson & Dr Jamie Fletcher Children's Cancer Institute |
Targeting BCL-2 family proteins in high-risk neuroblastoma |
Dr Maya Kansara & Prof David Thomas Garvan Institute of Medical Research |
Investigation of conventional chemotherapy and immunomodulatory strategies in bone cancer |
Dr Maya Kansara & Prof David Thomas Garvan Institute of Medical Research |
Targeting immune checkpoint blockers in bone cancer |
Microbiome Research Centre, St George and Sutherland Clinical School |
Role of the microbiome in lung cancer and its treatment. |
St George & Sutherland Clinical School |
Exosomal miRNAs in prostate cancer radioresistance |
A/Prof Elgene Lim & Dr Alex Swarbrick Garvan Institute of Medical Research |
IL6/JAK/STAT as novel targets in breast cancer |
A/Prof Elgene Lim & Dr Alex Swarbrick Garvan Institute of Medical Research |
New targeted therapeutic strategies for chemo-resistant breast cancers |
Department of Pharmacology, SoMS |
Targeting Wnt signalling pathways in colorectal cancer |
Children's Cancer Institute |
The critical roles of long noncoding RNAs in tumourigenesis and as targets for cancer therapy |
Children's Cancer Institute |
Enhancing the anticancer efficacy of transcriptional super-enhancer inhibitors |
Prof Richard Lock & Dr Cara Toscan Children’s Cancer Institute |
Mechanisms of AKR1C3 gene expression in paediatric acute lymphoblastic leukaemia with respect to sensitivity to the AKR1C3-activated prodrug OBI-3424 |
Dr Karen MacKenzie & Dr Toby Trahair Children's Cancer Institute |
Discovery and testing of new treatments for paediatric inflammatory myofibroblastic tumours |
Children's Cancer Institute |
Targeting telomerase components in paediatric cancer
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Dr Angelica Merlot & Prof Maria Kavallaris Children's Cancer Institute |
Dissecting the role of endoplasmic reticulum stress in cancer cell progression and metastasis in the tumour microenvironment |
Dr Angelica Merlot & Prof Maria Kavallaris Children's Cancer Institute |
Developing albumin-based nanoparticles that overcome drug resistance and metastasis |
A/Prof Ewan Millar & Dr Julia Beretov St George & Sutherland Clinical School |
Proteomic approaches in biomarker development for breast cancer |
Garvan Institute of Medical Research |
Micro-RNA regulators of radiotherapy resistance in breast cancer |
Dr Max Nobis & A/Prof Paul Timpson Garvan Institute of Medical Research |
Using in vivo imaging to target DNA damage response and PI3K signalling in pancreatic cancer |
Dr Marina Pajic, Ms Ashleigh Parkin & A/Prof Ruta Gupta Garvan Institute of Medical Research |
Development of tailored treatment approaches for head and neck squamous cell carcinoma |
Garvan Institute of Medical Research |
The role of subcapsular sinus (SCS) macrophages in LN melanoma metastases |
Transcriptional regulation of muscle wasting in cancer | |
Single Molecule Science, SoMS |
How do force-sensing ion channels influence melanoma migration? |
Prince of Wales Clinical School |
Role of nanoparticles in treatment of brain tumours (Collaboration with Lowy cancer institute, School of Materials Science & Engineering and Faculty of Engineering UNSW) |
Prince of Wales Clinical School |
Evaluation of prognosis of diffuse glioma based on molecular markers |
Garvan Institute of Medical Research |
Using genomic technology to study the rogue cells that cause autoimmune disease and cancer |
SWS Clinical School and Ingham Institute for Applied Medical Research |
Circulating tumour cells in liver cancer: Personalised cancer diagnosis and management |
SWS Clinical School and Ingham Institute for Applied Medical Research |
Understanding the genetic diversity of liver cancer: A hallmark of cancer risk and behavior (Honours & MSc) |
SWS Clinical School and Ingham Institute for Applied Medical Research |
Novel antibody and siRNA mediated therapy in liver cancer (Honours & MSc) |
Dr Julie Thoms, Dr Dominik Beck & Prof John Pimanda Adult Cancer Program & SoMS |
Characterisation of lincRNAs that predict patient outcome in AML |
Dr Julie Thoms & Prof John Pimanda Adult Cancer Program & SoMS |
The role of stem cell enhancers in normal and leukaemic blood development |
How is cellular energy metabolism altered in cancer? | |
Dr Vinod Vijay Subhash, Dr Jamie Fletcher & Dr Toby Trahair Children's Cancer Institute |
The role of tumour-derived exosomes in dissemination and metastasis of neuroblastoma |
Dr Vinod Vijay Subhash, Dr Jamie Fletcher & Dr Toby Trahair Children's Cancer Institute |
Cancer stem cells in neuroblastoma chemo resistance and metastasis |
Children's Cancer Institute |
Epigenetic regulation of leukaemia stem cells |
Children's Cancer Institute |
Developing a new curative therapy for aggressive leukaemia |
New drugs to target NAD+ and sirtuins in liver cancer | |
Substrate partitioning and the Warburg effect: why do cancer cells not use oxygen? |
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A/Prof Amany Zekry & Dr Lan Gong Microbiome Research Centre, St George and Sutherland Clinical School |
The role of the microbiome in obesity related liver inflammation and liver cancer |