SoMS Honours

SoMS Honours

Potential Projects » Cancer

 

Academic Project Title

Prof Minoti Apte & Prof Jeremy Wilson

SWS Clinical School and Ingham Institute for Applied Medical Research

Novel therapeutic approaches for pancreatic cancer – characterising and targeting stromal-tumour interactions

A/Prof Therese Becker

Centre for Circulating Tumor Cell Diagnostics & Research, Ingham Institute for Applied Medical Research

Liquid biopsies for the detection of clinically relevant biomarkers in brain cancer

Dr Annemiek Beverdam

Developmental and Regenerative Dermatology Unit, SoMS

Role of YAP in skin stem cell development and regeneration and in skin cancer

A/Prof Till BoeckingProf Peter Gunning

Single Molecule Science & Cellular and Genetic Medicine Unit, SoMS

Assembly mechanisms of cancer-associated actin filaments

Dr Nicole Bryce & Prof Peter Gunning

Cellular and Genetic Medicine Unit, SoMS

Molecular mechanisms of a novel class of cytoskeleton targeted anti-cancer compounds

Dr Liz Caldon

Garvan Institute of Medical Research

DNA damage in hormone resistant breast cancer

Dr Liz Caldon

Garvan Institute of Medical Research

Quantitative analysis of genome stability in human tumour samples

Dr Christine ChafferDr David Gallego Ortega

Garvan Institute of Medical Research

Defining the aggressive cancer cells that drive cancer development and metastasis using single-cell genomics

Dr Belamy Cheung

Children's Cancer Institute

Inhibiting the MYCN oncogenic signal

Dr Belamy Cheung

Children's Cancer Institute

Chemical inhibition of ubiquitin-specific proteases for targeting MYCN protein stability

Dr Arcadi Cipponi

Garvan Institute of Medical Research

Stress-induced genomic instability as a driver of adaptive responses in human cancer cells

Dr Thomas Cox

Garvan Institute of Medical Research

Understanding the role of the extracellular matrix in cancer progression

Dr David Croucher

Garvan Institute of Medical Research

Modelling tumour adaptation with single-cell kinase biosensors

Prof Peter Croucher

Garvan Institute of Medical Research

ProMis: Prostate cancer metastasis
Transcriptional profiling of dormant prostate cancer cells in the skeleton 
 

Dr Caroline Ford

Adult Cancer Program

Novel receptors in ovarian cancer: potential targets for personalised medicine?

Dr Caroline Ford

Adult Cancer Program

The role of Wnt signalling in aggressive endometrial cancer

Dr David Gallego Ortega

Garvan Institute of Medical Research

Development of immunotherapies for breast cancer

Prof Edna Hardeman & Prof Peter Gunning

Cellular and Genetic Medicine Unit, SoMS

Visualising the impact of anti-cancer drugs on cell dynamics in vivo

Dr Michelle Henderson

Children's Cancer Institute

Identification and characterization of novel MLL inhibitors

A/Prof Jeff Holst

Translational Cancer Metabolism Laboratory, SoMS & POW Clinical School

Developing new therapies targeting cancer metabolism in melanoma, prostate and breast cancer

A/Prof Phoebe Phillips

Adult Cancer Program & SoMS

Disrupting the epigenetic core machinery in pancreatic cancer stem cells for induction of long-lasting tumour remission

Prof David Goldstein

Prince of Wales Clinical School

(Epi-)Genetic profiling of circulating cancer (stem) cells in patients with metastatic pancreatic ductal adenocarcinoma

Dr Xiao-Tao JiangDr Howard Yim

Microbiome Research Centre, St George and Sutherland Clinical School

The role of enteric virome in colon cancer

Dr MoonSun JungDr Caroline Atkinson 

Children's Cancer Institute 

Developing mouse models for high-risk neuroblastoma metastasis using bioluminescent patient-derived xenograft (PDX) cells

Dr Nadeem Kaakoush

Cancer Institute NSW Fellow, SoMS

Examining the role of the oesophageal microbiome in the oesophageal adenocarcinoma cascade

Dr Alvin Kamili & Dr Jamie Fletcher

Children's Cancer Institute 

Pre-clinical modelling of new therapies for high-risk neuroblastoma

Dr Alvin Kamili & Dr Ruby Pandher

Children's Cancer Institute 

Lipidomic profiling of high-risk neuroblastoma for the identification of novel biomarkers and therapeutic targets

Dr Alvin Kamili, Dr Caroline Atkinson & Dr Jamie Fletcher

Children's Cancer Institute 

Targeting BCL-2 family proteins in high-risk neuroblastoma

Dr Maya Kansara & Prof David Thomas

Garvan Institute of Medical Research

Investigation of conventional chemotherapy and immunomodulatory strategies in bone cancer

Dr Maya Kansara & Prof David Thomas

Garvan Institute of Medical Research

Targeting immune checkpoint blockers in bone cancer

A/Prof Maija Kohonen-Corish

Microbiome Research Centre, St George and Sutherland Clinical School

Role of the microbiome in lung cancer and its treatment.
 

A/Prof Yong Li & Dr Kevin Ni

St George & Sutherland Clinical School

Exosomal miRNAs in prostate cancer radioresistance

A/Prof Elgene Lim & Dr Alex Swarbrick

Garvan Institute of Medical Research

IL6/JAK/STAT as novel targets in breast cancer

A/Prof Elgene Lim & Dr Alex Swarbrick

Garvan Institute of Medical Research

New targeted therapeutic strategies for chemo-resistant breast cancers

Dr Johnson Liu

Department of Pharmacology, SoMS

Targeting Wnt signalling pathways in colorectal cancer

Dr Tao Liu

Children's Cancer Institute 

The critical roles of long noncoding RNAs in tumourigenesis and as targets for cancer therapy

Dr Tao Liu

Children's Cancer Institute

Enhancing the anticancer efficacy of transcriptional super-enhancer inhibitors

Prof Richard Lock & Dr Cara Toscan

Children’s Cancer Institute

Mechanisms of AKR1C3 gene expression in paediatric acute lymphoblastic leukaemia with respect to sensitivity to the AKR1C3-activated prodrug OBI-3424

Dr Karen MacKenzie & Dr Toby Trahair

Children's Cancer Institute 

Discovery and testing of new treatments for paediatric inflammatory myofibroblastic tumours

Dr Karen MacKenzie

Children's Cancer Institute

Targeting telomerase components in paediatric cancer

Dr Angelica Merlot & Prof Maria Kavallaris

Children's Cancer Institute

Dissecting the role of endoplasmic reticulum stress in cancer cell progression and metastasis in the tumour microenvironment

Dr Angelica Merlot & Prof Maria Kavallaris

Children's Cancer Institute

Developing albumin-based nanoparticles that overcome drug resistance and metastasis

A/Prof Ewan Millar & Dr Julia Beretov

St George & Sutherland Clinical School

Proteomic approaches in biomarker development for breast cancer

Dr Tim Molloy

Garvan Institute of Medical Research

Micro-RNA regulators of radiotherapy resistance in breast cancer

Dr Max Nobis & A/Prof Paul Timpson

Garvan Institute of Medical Research

Using in vivo imaging to target DNA damage response and PI3K signalling in pancreatic cancer

Dr Marina Pajic, Ms Ashleigh Parkin & A/Prof Ruta Gupta

Garvan Institute of Medical Research

Development of tailored treatment approaches for head and neck squamous cell carcinoma

Dr Tri Phan & Dr Akira Nguyen

Garvan Institute of Medical Research

The role of subcapsular sinus (SCS) macrophages in LN melanoma metastases

A/Prof Patsie Polly & Dr Timothy Tan

Cancer Cachexia Mechanisms Research Group, SoMS

Transcriptional regulation of muscle wasting in cancer

Dr Kate Poole

Single Molecule Science, SoMS

How do force-sensing ion channels influence melanoma migration?

Dr Prashanth J Rao

Prince of Wales Clinical School

Role of nanoparticles in treatment of brain tumours (Collaboration with Lowy cancer institute, School of Materials Science & Engineering and Faculty of Engineering UNSW) 

Dr Prashanth J Rao

Prince of Wales Clinical School

Evaluation of prognosis of diffuse glioma based on molecular markers

Dr Joanne Reed

Garvan Institute of Medical Research

Using genomic technology to study the rogue cells that cause autoimmune disease and cancer

Prof Nicholas Shackel

SWS Clinical School and Ingham Institute for Applied Medical Research

Circulating tumour cells in liver cancer: Personalised cancer diagnosis and management

Prof Nicholas Shackel

SWS Clinical School and Ingham Institute for Applied Medical Research

Understanding the genetic diversity of liver cancer: A hallmark of cancer risk and behavior (Honours & MSc)

Prof Nicholas Shackel

SWS Clinical School and Ingham Institute for Applied Medical Research

Novel antibody and siRNA mediated therapy in liver cancer (Honours & MSc)

Dr Julie Thoms, Dr Dominik BeckProf John Pimanda

Adult Cancer Program & SoMS

Characterisation of lincRNAs that predict patient outcome in AML

Dr Julie Thoms & Prof John Pimanda

Adult Cancer Program & SoMS

The role of stem cell enhancers in normal and leukaemic blood development

A/Prof Nigel Turner

Mitochondrial Bioenergetics Group, SoMS

How is cellular energy metabolism altered in cancer?

Dr Vinod Vijay SubhashDr Jamie Fletcher & Dr Toby Trahair

Children's Cancer Institute 

The role of tumour-derived exosomes in dissemination and metastasis of neuroblastoma

Dr Vinod Vijay SubhashDr Jamie Fletcher & Dr Toby Trahair

Children's Cancer Institute 

Prognostic significance of circulating tumour cells (CTCs) in neuroblastoma

Dr Jenny Wang

Children's Cancer Institute

Epigenetic regulation of leukaemia stem cells 

Dr Jenny Wang

Children's Cancer Institute

Developing a new curative therapy for aggressive leukaemia 

Dr Lindsay Wu & Prof David Sinclair

Molecular Biology of Ageing, SoMS

New drugs to target NAD+ and sirtuins in liver cancer

Dr Lindsay Wu & Prof David Sinclair

Molecular Biology of Ageing, SoMS

Substrate partitioning and the Warburg effect: why do cancer cells not use oxygen?

A/Prof Amany ZekryDr Lan Gong 

Microbiome Research Centre, St George and Sutherland Clinical School

The role of the microbiome in obesity related liver inflammation and liver cancer