Research Support » Paper of the Month

This award was instigated by the Research Support Committee in July 2004 to promote and reward quality research within SoMS, and to help advance the trajectory of SOMS students and staff. Staff are encouraged to send to the RSC all papers recently accepted for publication, and these will automatically be considered for the PoM. Publications will be considered for 3 months after being accepted for publication.

The PoM award is adjudicated by the research support committee at their monthly meeting, who take into account the following selection criteria:

  • A member of staff or a student in the School of Medical Sciences being 1st author
  • Author affiliation with SoMS clearly identified
  • The extent to which the work was undertaken in SoMS
  • Whether the 1st author is a SOMS student or ECR whose career trajectory may benefit from the PoM award
  • Whether the 1st author has previously received a SOMS PoM
  • The standing of the journal in which the work was published, judged primarily by ranking in the discipline
  • Other measures of significance or impact
  • Whether the paper has further chances to be considered for the PoM award
  • Whether this represents a new research group, collaboration and/or new field
  • Whether the paper received additional accolades such as an editorial, commentary or front cover image

The submission should highlight how the publication addresses any of the criteria above, a brief summary, and any other points thought relevant to the merit and/or impact of the paper

Papers must be submitted to Marie Kwok once accepted for publication and accessible on publication databases (ie appearing online or published)

Previous awardees:

July 2017
A FRET sensor enables quantitative measurements of membrane charges in live cells Nature Biotechnology, doi:10.1038/nbt.3828

Authors: Yuanqing Ma, Yui Yamamoto, Philip R Nicovich, Jesse Goyette, Jérémie Rossy, J Justin Gooding and Katharina Gaus

June 2017
Regulation of the nitric oxide oxidase activity of myeloperoxidase by pharmacological agents Biochemical Pharmacology,
Authors: Sophie L Maiocchi, Jonathan C Morris, Martin D Rees, Shane R Thomas

May 2017
The effects of high-intensity interval training vs. moderate-intensity continuous training on body composition in overweight and obese adults: a systematic review and meta-analysis Obesity Reviews, 18: 635–46. doi: 10.1111/obr.12532
Authors: Michael Wewege, Roanna van den Berg, Rachel E Ward and Andrew Keech

April 2017
An intermolecular FRET sensor detects the dynamics of T cell receptor clustering Nature Communications, doi: 10.1038/ncomms15100
Authors: Yuanqing Ma, Elvis Pandzic, Philip R Nicovich, Yui Yamamoto, Joanna Kwiatek, Sophie V Pageon, Aleš Benda, Jérémie Rossy, Katharina Gaus

March 2017
Characterisation of Immune and Neuroinflammatory Changes Associated with Chemotherapy-Induced Peripheral Neuropathy Plos ONE, doi:10.1371/journal.pone.0170814
Authors: Preet GS Makker, Samuel S Duffy, Justin G Lees, Chamini J Perera, Ryan S Tonkin, Oleg Butovsky, Susanna B Park, David Goldstein, Gila Moalem-Taylor

February 2017
Cafeteria diet and probiotic therapy: Cross talk among memory, neuroplasticity, serotonin receptors, and gut microbiota in the rat Molecular Psychiatry doi:10.1038/mp.2017.38
Authors: Jessica Beilharz, Nadeem Kaakoush, Jayanthi Maniam, Margaret Morris

January 2017
Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice Science 354 (6314): 904-908. doi: 10.1126/science.aah6205.
Authors: Arne Ittner, Sook Wern Chua, Josefine Bertz, Alexander Volkerling, Julia van der Hoven, Amadeus Gladbach, Magdalena Przybyla, Mian Bi, Annika van Hummel, Claire H Stevens, Stefania Ippati, Lisa S Suh, Alexander Macmillan, Greg Sutherland, Jillian J Kril, Ana PG Silva, Joel Mackay, Anne Poljak, Fabien Delerue, Yazi D Ke, Lars M Ittner

December 2016
Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes Scientific Reports, doi: 10.1038/srep40159
Authors: Md. Kamrul Hasan Chowdhury, Nigel Turner, Nicholas L Bentley, Abhirup Das, Lindsay E Wu, Dulama Richani, Sonia Bustamante, Robert B Gilchrist, Margaret J Morris, Peter R Shepherd and Greg C Smith

November 2016
Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination Proceedings of the National Academy of Sciences USA,113(37): E5454-E5463, doi: 10.1073/pnas.1607436113
Authors: Sophie V Pageon, Thibault Tabarin, Yui Yamamoto, Yuanqing Ma, John S Bridgeman, André Cohnen, Carola Benzing, Yijun Gao, Michael D Crowther, Katie Tungatt, Garry Dolton, Andrew K Sewell, David A. Price, Oreste Acuto, Robert G Parton, J. Justin Gooding, Jérémie Rossy, Jamie Rossjohn, Katharina Gaus

October 2016
Historical trends in the hepatitis C virus epidemics in North America and Australia The Journal of Infectious Diseases, doi: 10.1093/infdis/jiw389
Authors: Chaturaka Rodrigo, Auda A Eltahla, Rowena A Bull, Jason Grebely, Gregory J Dore, Tanya Applegate, Kimberly Page, Julie Bruneau, Meghan D Morris, Andrea L Cox, William Osburn, Arthur Y Kim, Janke Schinkel, Naglaa H Shoukry, Georg M Lauer, Lisa Maher, Margaret Hellard, Maria Prins, Chris Estes, Homie Razavi, Andrew R Lloyd, and Fabio Luciani, InC3 Study Group

September 2016 - joint winners
Leukocyte immunoglobulin-like receptor B4 regulates key signalling molecules involved in FcγRI-mediated clathrin-dependent endocytosis and phagocytosis Scientific Report, doi: 10.1038/srep35085
Authors: Mijeong Park, Mark J Raftery, Paul S Thomas, Carolyn L Geczy, Katherine Bryant and Nicodemus Tedla

September 2016 - joint winners
Epidermal YAP2-5SA-ΔC Drives β-Catenin Activation to Promote Keratinocyte Proliferation in the Mouse Skin in Vivo Journal of Investigative Dermatology, doi: 10.1016/j.jid.2016.10.029
Authors: Bassem Akladios, Veronica Mendoza-Reinoso, Michael S Samuel, Edna C Hardeman, Kiarash Khosrotehrani, Brian Key, Annemiek Beverdam

August 2016
Descending projections from the inferior colliculus to medial olivocochlear efferents: Mice with normal hearing, early onset hearing loss, and congenital deafness Hearing Research, doi: 10.1016/j.heares.2016.06.014
Authors: Kirupa Suthakar, David Ryugo

July 2016
In vivo PET imaging with [18F]FDG to explain improved glucose uptake in an apolipoprotein A-I treated mouse model of diabetes Diabetologia (2016) 59: 1977–1984
Authors: Blake J Cochran, William J Ryder, Arvind Parmar, Shudi Tang, Anthonin Reilhac, Andrew Arthur, Arnaud Charil, Hasar Hamze, Philip J Barter, Leonard Kritharides, Steven R Meikle, Marie-Claude Gregoire, Kerry-Anne Rye

June 2016
Prolonged Intake of Dietary Lipids Alters Membrane Structure and T Cell Responses in LDLr2/2 Mice Journal of Immunology, doi: 10.4049/jimmunol.1501261
Authors: Abigail H Pollock, Nicodemus Tedla, Sarah E Hancock, Rhea Cornely, Todd W Mitchell, Zhengmin Yang, Maaike Kockx, Robert G Parton, Jeremie Rossy and Katharina Gaus

May 2016
Tropomyosin Promotes Lamellipodial Persistence by Collaborating with Arp2/3 at the Leading Edge Current Biology, doi: 10.1016/j.cub.2016.03.028
Authors: Simon Brayford, Nicole S Bryce, Galina Schevzov, Elizabeth M Haynes, James E Bear, Edna C Hardeman and Peter W Gunning 

April 2016
Linking the T cell receptor to the single cell transcriptome in antigen-specific human T cells Immunology and Cell Biology, doi:10.1038/icb.2016.16
Authors: Auda A Eltahla, Simone Rizzetto, Mehdi R Pirozyan, Brigid D Betz-Stablein, Vanessa Venturi, Katherine Kedzierska, Andrew R Lloyd, Rowena A Bull and Fabio Luciani 

March 2016
Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness Nature Communications, 7:11047, doi: 10.1038/ncomms11047
Authors: Elizabeth Hinde, Elvis Pandzic, Zhengmin Yang, Ivan HW Ng, David A Jans, Marie A Bogoyevitch, Enrico Gratton and Katharina Gaus 

February 2016
Soluble LILRA3 promotes neurite outgrowth and synapses formation through high affinity interaction with Nogo 66 Journal of Cell Science 129:1198-1209, doi: 10.1242/jcs.182006
Authors: Hongyan An, Merryn Brettle, Terry Lee, Benjamin Heng, Chai K Lim, Gilles J Guillemin, Megan S Lord, Enrico Klotzsch, Carolyn L Geczy, Katherine Bryant, Thomas Fath, Nicodemus Tedla

January 2016
Binding of transcription factor GabR to DNA requires recognition of DNA shape at a location distinct from its cognate binding site, Nucleic Acids Research doi: 10.1093/nar/gkv1466
Authors: Walid A Al-Zyoud, Robert MG Hynson, Lorraine A Ganuelas, Adelle CF Coster, Anthony P Duff, Matthew AB Baker, Alastair G Stewart, Eleni Giannoulatou, Joshua WK Ho, Katharina Gaus, Dali Liu, Lawrence K Lee and Till Böcking 

December 2015
Hyperuricaemia: contributions of urate transporter ABCG2 and the fractional renal clearance of urate Annals of the Rheumatic Diseases, doi: 10.1136/annrheumdis-2015-208111.
Authors: Diluk RW Kannangara, Amanda J Phipps-Green, Nicola Dalbeth, Lisa K Stamp, Kenneth M Williams, Garry G Graham, Richard O Day, Tony R Merriman

November 2015
Maternal obesity regulates gene expression in the hearts of offspring Nutrition, Metabolism and Cardiovascular Diseases, 25: 881-888.
Authors: Mukesh Raipuria, Georgia O Hardy, Hasnah Bahari, Margaret J Morris

October 2015
Amyotrophic lateral sclerosis-associated mutant profilin 1 increases dendritic arborisation and spine formation in primary hippocampal neurons Neuroscience Letters 609 (2015) 223-228
Authors: Merryn Brettle, Alexandra K Suchowerska, Sook W Chua, Lars M Ittner, Thomas Fath

September 2015
Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS, Acta Neuropathologica, doi: 10.1007/s00401-015-1486-0. 
Authors: Yazi D Ke, Annika van Hummel, Claire H Stevens, Amadeus Gladbach, Stefania Ippati, Mian Bi, Wei S Lee, Sarah Krüger, Julia van der Hoven, Alexander Volkerling, Andre Bongers, Glenda Halliday, Nikolas K Haass, Matthew Kiernan, Fabien Delerue, Lars M Ittner 

August 2015
The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation Human Genetics, doi: 10.1007/s00439-015-1591-0 
Authors: Paulina Carmona‑Mora, Jocelyn Widagdo, Florence Tomasetig, Cesar P Canales, Yeojoon Cha, Wei Lee, Abdullah Alshawaf, Mirella Dottori, Renee M Whan, Edna C Hardeman, Stephen J Palmer   

July 2015
Clinical outcomes of xeno-free expansion and transplantation of autologous ocular surface epithelial stem cells via contact lens delivery: a prospective case series Stem Cell Research & Therapy, doi: 10.1186/s13287-015-0009-1. 
Authors: Samantha Bobba, Sharron Chow, Stephanie Watson and Nick Di Girolamo

June 2015
Type II spiral ganglion afferent neurons drive medial olivocochlear reflex suppression of the cochlear amplifier Nature Communications 6:7115 doi:10.1038/ncomms8115. 
Authors: Kristina E Froud, Ann Chi Yan Wong, Jennie ME Cederholm, Matthias Klugmann, Shaun L Sandow, Jean-Pierre Julien, Allen F Ryan and Gary Housley

May 2015
Hypoxic postconditioning reduces microglial activation, astrocyte and caspase activity and inflammatory markers after hypoxia-ischaemia in the neonatal rat brain Pediatric Research doi: 10.1038/pr.2015.47
Authors: Jonathan D Teo, Margaret J Morris and Nicole M Jones

April 2015
Transmission of Hepatitis C Virus among Prisoners, Australia, 2005-2012 Emerging Infectious Diseases 21(5): 765-74
Authors: Neil Arvin Bretaña, Lies Boelen, Rowena Bull, Suzy Teutsch, Peter A White, Andrew R Lloyd, Fabio Luciani

March 2015
Active immunization with myelin-derived altered peptide ligand reduces mechanical pain hypersensitivity following peripheral nerve injury Journal of Neuroinflammation doi: 10.1186/s12974-015-0253-4
Authors: Chamini J Perera, Samuel S Duffy, Justin G Lees, Cristina F Kim, Barbara Cameron, Vasso Apostolopoulos and Gila Moalem-Taylor

February 2015
Septal glucagon-like peptide 1 receptor expression determines suppression of cocaine-induced behavior Neuropsychopharmacology doi: 10.1038/npp.2015.47
Authors: Anne E Harasta, John M Power, Georg von Jonquieres, Tim Karl, Daniel J Drucker, Gary D Housley, Miriam Schneider and Matthias Klugmann

January 2015
ISU201 enhances the resolution of airway inflammation in a mouse model of an acute exacerbation of asthma Mediators of Inflammation
Authors: Yuka Hiroshima, Linda Garthwaite, Kenneth Hsu, Hyouna Yoo, Sang-Ho Park, Carolyn L Geczy, Rakesh K Kumar, Cristan Herbert

December 2014
Spontaneously hypertensive rats have more orexin neurons in their medial hypothalamus than normotensive rats Experimental Physiology doi: 10.1113/expphysiol.2014.084137
Authors: Liam Clifford, Bruno W Dampney and Pascal Carrive

November 2014
DNA methylation in the apolipoprotein-A1 gene is associated with episodic memory performance in healthy older individuals Journal of Alzheimer’s Disease 44(1): 175–182
Authors: Jessica Lazarus, Karen A Mather, Nicola J Armstrong, Fei Song, Anne Poljak, Anbupalam Thalamuthu, Teresa Lee, Nicole A Kochan, Henry Brodaty, Margaret J Wright, David Ames, Perminder S Sachdevand John BJ Kwok

October 2014
Degradation of emotion processing ability in corticobasal syndrome and Alzheimer’s disease Brain 137 (Pt 11) 3061-72
Authors: Fiona Kumfor, Laurie-Anne Sapey-Triomphe, Cristian E Leyton, James R Burrell, John R Hodges and Olivier Piguet

September 2014
The role of GTF2IRD1 in the auditory pathology of Williams–Beuren Syndrome  European Journal of Human Genetics, doi: 10.1038/ejhg.2014.188
Authors: Cesar P Canales, Ann CY Wong, Peter W Gunning, Gary D Housley, Edna C Hardeman and Stephen J Palmer

August 2014
Targeting the motor end plates in the mouse hindlimb gives access to a greater number of spinal cord motor neurons: an approach to maximize retrograde transport, Neuroscience 274: 318–330
Authors: Rahul Mohan, Andrew P Tosolini and Renee Morris

July 2014
Aerobic Training Increases Pain Tolerance in Healthy Individuals Medicine & Science in Sports & Exercise, 46(8): 1640-7
Authors: Matthew D Jones, John Booth, Janet L Taylor and Benjamin K Barry

June 2014
Online testable concept maps: benefits for learning about the pathogenesis of disease Medical Education 48: 687–697
Authors: Veronica Ho, Rakesh K Kumar, Gary Velan

May 2014
The nucleotide exchange factor SIL1 is required for glucose-stimulated insulin secretion from mouse pancreatic beta cells in vivo Diabetologia 57: 1410–1419
Authors: Arne A Ittner, Josefine Bertz, Tse Yan Becky Chan, Janet van Eersel, Patsie Polly, Lars M Ittner

April 2014
Close-Field Electroporation Gene Delivery Using the Cochlear Implant Electrode Array Enhances the Bionic Ear Science Translational Medicine 6(233): 233ra54
Authors: Jeremy L Pinyon, Sherif F Tadros, Kristina E Froud, Ann CY Wong, Isabella T Tompson, Edward N Crawford, Myungseo Ko, Renée Morris, Matthias Klugmann, Gary D Housley

March 2014
Acute resistance exercise and pressure pain sensitivity in knee osteoarthritis: a randomised crossover trial Osteoarthritis and Cartilage 22(3): 407-414
Authors: Nicholas J Burrows, John Booth, Daina L Sturnieks, Benjamin K Barry

February 2014
Resolvin E1 promotes resolution of inflammation in a mouse model of an acute exacerbation of allergic asthma, Clinical Science 126, 805-814
Authors: Rylie Flesher, Cristan Herbert and Ramesh Kumar

January 2014
Changes in Oxidative Damage, Inflammation and [NAD(H)] with Age in Cerebrospinal Fluid PLoS ONE, 9(1): e85335
Authors: Jade Guest, Ross Grant, Trevor A Mori, Kevin D Croft

December 2013
Long-Term Valproate Treatment Increases Brain Neuropeptide Y Expression and Decreases Seizure Expression in a Genetic Rat Model of Absence Epilepsy PLoS ONE, 8(9): e73505
Authors: Johanna Elms, Kim L Powell, Leena van Raay, Stefanie Dedeurwaerdere, Terence J O’Brien, Margaret J Morris

November 2013
Glycosylation in a mammalian expression system is critical for the production of functionally active leukocyte immunoglobulin-like receptor A3 protein Journal of Biological Chemistry, jbc.M113.478578
Authors: Terry HY Lee, Ainslie Mitchell, Sydney Liu Lau, Hongyan An, Poornima Rajeaskariah, Valerie Wasinger, Mark Raftery, Katherine Bryant, Nicodemus Tedla

October 2013
A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells Cancer Research, 73: 5169-5182
Authors: Justine R. Stehn, Nikolas K. Haass, Teresa Bonello, Melissa Desouza, Gregg Kottyan, Herbert Treutlein, Jun Zeng, Paula R.B.B. Nascimento, Vanessa B. Sequeira, Tanya L. Butler, Munif Allanson, Thomas Fath, Timothy A. Hill, Adam McCluskey, Galina Schevzov, Stephen J. Palmer, Edna C. Hardeman, David Winlaw, Vivienne E. Reeve, Ian Dixon, Wolfgang Weninger, Timothy P. Cripe and Peter W. Gunning

September 2013
5-HT1A receptor pharmacophores to screen for off-target activity of α1-adrenoceptor antagonists Journal of Computer-Aided Molecular Design, 27: 305-319
Authors: Tony Ngo, Timothy J Nicholas, Junli Chen, Angela M Finch, Renate Griffith

August 2013
Mast Cell–Restricted, Tetramer-Forming Tryptases Induce Aggrecanolysis in Articular Cartilage by Activating Matrix Metalloproteinase-3 and -13 Zymogens Journal of Immunology, 191: 1404-1412
Authors: Natalia J Magarinos, Katherine J Bryant, Amanda J Fosang, Roberto Adachi, Richard L Stevens and H Patrick McNeil

July 2013
The orbitofrontal cortex is involved in emotional enhancement of memory: evidence from the dementias Brain, doi:10.1093/brain/awt185
Authors: Fiona Kumfor, Muireann Irish, John R Hodges and Olivier Piguet 

June 2013
α1-Adrenoceptor and serotonin 5-HT(1A) receptor affinity of homobivalent 4-aminoquinoline compounds: An investigation of the effect of linker length Biochemical Pharmacology, 15; 85(10): 1534-41
Authors: Junli Chen, Ahsan K Murad, Laurence PG Wakelin, William A Denny, Renate Griffith, Angela M Finch

May 2013
ATP-gated ion channels mediate adaptation to elevated sound levels, P NATL ACAD SCI USA (PNAS) 110(18): 7494–99.
Authors: Gary D. Housley, Rachel Morton-Jones, Srdjan M. Vlajkovic, Ravindra S. Telang, Vinthiya Paramananthasivam, Sherif F. Tadros, Ann Chi Yan Wong, Kristina E. Froud, Jennie M.E. Cederholm, Yogeesan Sivakumaran, Peerawuth Snguanwongchai, Baljit S. Khakh, Debra A. Cockayne, Peter R. Thorneand Allen F. Ryan 

April 2013
Expression and localization of pannexin-1 hemichannels in human colon in health and disease Neurogastroenterology and Motility, doi: 10.1111/nmo.12130
Authors: E F Diezmos, S L Sandow, I Markus, D Shevy Perera, D Z Lubowski, D W King, P P Bertrand, L Liu

March 2013
Effects of Axonal Ion-Channel Dysfunction on Quality of Life in Type 2 Diabetes, Diabetes Care, doi:10.2337/dc12-1310
Authors: Natalie Kwai, Ria Arnold, Chathu Wikerema, Cindy Lin, Ann Poynten, Matthew Kiernan, Arun Krishnan

February 2013
Increasing Viral Dose Causes a Reversal in CD8+ T Cell Immunodominance during Primary Influenza Infection due to Differences in Antigen Presentation, T Cell Avidity, and Precursor Numbers Journal of Immunology, doi: 10.4049/jimmunol.1200089
Authors: Fabio Luciani, Megan Sanders, Sara Oveissi, Ken Pang, Weisan Chen

January 2013
Bringing words back to mind – Improving word production in semantic dementia Cortex,
Authors: Sharon Savage, Kirrie Ballard, Olivier Piguet, John Hodges

December 2012
High-intensity intermittent exercise and cardiovascular and autonomic function Clinical Autonomic Research 23(1): 57-65
Authors: Mehrdad Heydari, Yati Boutcher, Stephen Boutcher

November 2012
SUMOylation of GTF2IRD1 Regulates Protein Partner Interactions and Ubiquitin-Mediated Degradation PLoS One 7(11): e49283. PMID: 23145142
Authors: Jocelyn Widagdo, Kylie M Taylor, Peter W Gunning, Edna C Hardeman, Stephen J Palmer

October 2012
Association Between Physical Activity and Risk of Bleeding in Children With Hemophilia, JAMA, 308(14): 1452-59
Authors: Carolyn Broderick, Robert Herbert, Jane Latimer, Chris Barnes, Julie Curtin, Erin Mathieu, Paul Monagle, Simon Brown

September 2012
Metformin therapy in patients with chronic kidney disease, Diabetes, Obesity and Metabolism, 14(10): 963-5
Authors: JK Duong, DM Roberts, TJ Furlong, SS Kumar, JR Greenfield, CM Kirkpatrick, GG Graham, KM Williams, RO Day

August 2012
Alternative Splicing of the TRPC3 Ion Channel Calmodulin/IP3 Receptor-Binding Domain in the Hindbrain Enhances Cation Flux Journal of Neuroscience, 32(33): 11414-23
Authors: Y Kim, AC Wong, JM Power, SF Tadros, M Klugmann, AJ Moorhouse, PP Bertrand, GD Housley

July 2012
Age-Associated Changes in Oxidative Stress and NAD+ Metabolism in Human Tissue PLoS ONE, 7(7): e42357
Authors: Hassina Massudi, Ross Grant, Nady Braidy, Jade Guest, Bruce Farnsworth, Gilles Guillemin

June 2012
Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity Cardiovascular Research, 95(4): 439-47
Authors: S Senadheera, Y Kim, TH Grayson, S Toemoe, MY Kochukov, J Abramowitz, GD Housley, RL Bertrand, PS Chadha, PP Bertrand, TV Murphy, M Tare, L Birnbaumer, SP Marrelli, SL Sandow

May 2012
Considering the role of semantic memory in episodic future thinking: evidence from semantic dementia Brain, 135(Pt 7): 2178-91
Authors: Muireann Irish, Donna Rose Addis, John Hodges, Olivier Piguet

April 2012
GIRK2 expression in dopamine neurons of the substantia nigra and ventral tegmental area Journal of Comparative Neurology, 520(12): 2591-607
Authors: Stefanie Reyes, Yuhong Fu, Kay Double, Lachlan Thompson, Deniz Kirik, George Paxinos, Glenda Halliday

March 2012
Disruption of MEF2C signaling and loss of sarcomeric and mitochondrial integrity in cancer-induced skeletal muscle wasting. Aging, 4(2): 133-143
Authors: Angie Shum, Theodore Mahendradatta, Ryland Taylor, Arran Painter, Melissa Moore, Maria Tsoli, Timothy Tan, Stephen Clarke, Graham Robertson, Patsie Polly

February 2012
Spatial characterization of the motor neuron columns supplying the rat forelimb. Neuroscience, 200:19-30
Authors: Andrew P Tosolini and Renee Morris

January 2012
Hypertrophy and dietary tyrosine ameliorate the phenotypes of a mouse model of severe nemaline myopathy Brain, 134; 3516–3529
Authors: Mai-Anh T Nguyen, Josephine E Joya, Anthony J Kee, Ana Domazetovska, Nan Yang, Jeff W.Hook, Frances A Lemckert, Emma Kettle, Valentina A Valova, Philip J Robinson, Kathryn N North, Peter W Gunning, Christina A Mitchell, Edna C Hardeman

December 2011
Early Hypothalamic FTO Overexpression in Response to Maternal Obesity – Potential Contribution to Postweaning Hyperphagia PLoS ONE 6(9): e25261. doi:10.1371/journal.pone.0025261
Authors: Vanni Caruso, Hui Chen, Margaret J Morris

November 2011
Sequential Bottlenecks Drive Viral Evolution in Early Acute Hepatitis C Virus Infection PLoS Pathogen, 7(9): e1002243
Authors: Rowena Bull, Fabio Luciani, Kerensa McElroy, Silvana Gaudieri, Son Pham, Abha Chopra, Barbara Cameron, Lisa Maher, Gregory Dore, Peter White, Andrew Lloyd

October 2011
Neural basis of music knowledge: evidence from the dementias Brain, 134: 2523-2534
Authors: Sharpley Hsieh, Michael Hornberger, Olivier Piguet, John Hodges

September 2011 - joint winner
Hemokinin-1 stimulates prostaglandin E2 production in human colon through activation of cyclooxygenase-2 and inhibition of 15-hydroxyprostaglandin dehydrogenase Journal of Pharmacology and Experimental Therapeutics (JPET), 340(1): 27-36
Authors: Liying Dai, D Shevy Perera, Denis King, Bridget Southwell, Elizabeth Burcher, Lu Liu

September 2011 - joint winner
Exploring DNA Topoisomerase I Ligand Space in Search of Novel Anticancer Agents PLoS ONE, 6(9): e25150
Authors: Malgorzata Drwal, Keli Agama, Laurence Wakelin, Yves Pommier, Renate Griffith

August 2011
Effect of alginate encapsulation on the cellular transcriptome of human islets Biomaterials, 32(33): 8416-25
Authors: Vijayaganapathy Vaithilingam, Nayeem Quayum, Mugdha Joglekar, Jan Jensen, Anandwardhan Hardikar, Jose Oberholzer, Gilles Guillemin, Bernard Tuch

July 2011
Tubuloglomerular feedback response in the prenatal and postnatal ovine kidney, Am J Physiol Renal Physiol; 300 F1368-F1374
Authors: Russell D Brown, Anita J Turner, Mattias Carlström, A Erik G Persson, Karen J Gibson

June 2011
A novel structural framework for α1A/D-adrenoceptor selective antagonists identified using subtype selective pharmacophores PLoS ONE, 6(5): e19695
Authors: Emily S Stoddart, Sevvandi Senadheera, Iain JA MacDougall, Renate Griffith, Angela M Finch

May 2011
Age related changes in NAD+ metabolism oxidative stress and sirt1 activity in Wistar rats PLoS ONE, 26; 6(4): e19194
Authors: Nady Braidy, Gilles J. Guillemin, Hussein Mansour, Tailoi Chan-Ling, Anne Poljak, Ross Grant

April 2011
A reassessment of stress-induced "analgesia" in the rat using an unbiased method Pain, 152: 676–686
Authors: Pascal Carrive, Maxim Churyukanov, Daniel Le Bars

March 2011
Ophthalmic pterygium - A stem cell disorder with premalignant features American Journal of Pathology, 178(2): 817–27
Authors: Jeanie Chui, Minas T Coroneo, Lien T Tat, Roger Crouch, Denis Wakefield, Nick Di Girolamo

February 2011
Interleukin-17 contributes to neuroinflammation and neuropathic pain following peripheral nerve injury in mice Journal of Pain, 12(3): 370-83
Authors: Cristina F Kim and Gila Moalem-Taylor

January 2011
Role of pancreatic stellate cells in pancreatic cancer metastasis, American Journal of Pathology 77(5): 2568-96
Authors: Zhihong Xu, Alain Vonlaufen, Phoebe Phillips, Eva Fiala-Beer, Xuguo Zhang, Lu Yang, Andrew Biankin, David Goldstein, Romano Pirola, Jeremy Wilson, Minoti Apte