Mitochondrial bioenergetics

About us

Research Focus

Mitochondria are the primary site of energy production within cells. Mitochondrial dysfunction has been linked with a number of inherited and acquired human diseases and has also been implicated in the ageing process. A major focus of our studies is to examine how alterations in mitochondrial function in different tissues influences insulin action in obesity and type 2 diabetes.

We are interested in how certain drugs and different types of dietary fats affect mitochondrial content and metabolism. We are also examining the role of post-translational modification in the function of mitochondrial proteins. Another area of research is the importance of alterations in mitochondrial bioenergetics in certain types of cancers.

 

image - Mitochondrial bioenergetics

 

 

News and Events  

  • March 2017 - Jayne Barbour submits her PhD thesis

        image - Mitochondrial bioenergetics

  • February 2017 - New funding received from the Diabetes Australia Research Program to investigate muscle lipids and insulin resistance
  • January 2017 - Menghan Liu submits her PhD thesis

        image - Mitochondrial bioenergetics

  • November 2016 - Two new project grants selected for funding by the National Health and Medical Research Council of Australia
  • November 2016 - Nic Bentley and Jayne Barbour give oral and poster presentations at the AussieMit Meeting, Sydney

       image - Mitochondrial bioenergetics

  • November 2016 - New article from the group published in BBA Mol Cell Biol Lipids

        image - Mitochondrial bioenergetics

  • October 2016 - Azrah Samsudeen delivers an oral presentation at the Garvan Signaling Meeting, Sydney
  • October 2016 - Menghan Liu publishes first paper from her PhD in Cancer & Metabolism

         image - Mitochondrial bioenergetics

  • August 2016 - Brenna Osborne wins the Pincus Taft Young Investigator Award at the Australian Diabetes Society Meeting
  • July 2016 - Lake-Ee Quek publishes paper in Cancer & Metabolism       

        image - Mitochondrial bioenergetics

  • April 2016 - Azrah Samsudeen wins best poster presentation at the Gage Muscle Conference, Canberra

 

Social

        image - Mitochondrial bioenergetics

        image - Mitochondrial bioenergetics

 

        image - Mitochondrial bioenergetics

 

        image - Mitochondrial bioenergetics

 

Team

Collaborators

Past Lab Members:

Dr Magda Montgomery, Research Fellow, Monash University

Dr Sanket Joshi, Research Fellow UNSW

Collaborators:

Professor David Sinclair, UNSW Sydney and Harvard Medical School, Boston

Professor Gregory Cooney, Charles Perkins Centre, University of Sydney

Associate Professor Todd Mitchell, University of Wollongong

 

Grants & Funding

Funding is provided by the National and Medical Health Research Council, the Australian Research Council and the Diabetes Australia Research Program.

Students

  • Jayne Barbour (PhD)
  • Menghan Liu (PhD)
  • Nicholas Bentley (PhD)
  • Ghazal Sultani (PhD)
  • Azrah Samsudeen (PhD)
  • Thomas Lakeland (PhD)
  • Louise Metcalfe (Honours)

Please contact us for current opportunities for talented Honours and PhD students