Mitochondrial bioenergetics

About us

Research Focus

Mitochondria are the primary site of energy production within cells. Mitochondrial dysfunction has been linked with a number of inherited and acquired human diseases and has also been implicated in the ageing process. A major focus of our studies is to examine how alterations in mitochondrial function in different tissues influences insulin action in obesity and type 2 diabetes.

We are interested in how certain drugs and different types of dietary fats affect mitochondrial content and metabolism. We are also examining the role of post-translational modification in the function of mitochondrial proteins. Another area of research is the importance of alterations in mitochondrial bioenergetics in certain types of cancers.

 

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News and Events  

  • June 2019 - Sarah Hancock delivers oral presentation at Metabolomics 2019 in the Netherlands
  • June 2019 - New article from the group published in the Journal of Clinical Medicine

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  •  April 2019 - New book chapter from the group published in Beatric Morio, Luc Penicaud, Michel Rigoulet (eds), Mitochondria in Obesity and Type 2 Diabetes, 1st Edition 

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  • April 2019 - Ghazal Sultani submits her PhD thesis

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  • March 2019 - New book chapter from the group in Majda Haznadar (ed.), Cancer Metabolism: Methods and Protocols, Methods in Molecular Biology, vol. 1928

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  • January 2019 - Sarah Hancock receives grant funding from Cure Cancer Australia to investigate metabolic heterogeneity in pancreatic cancer through the Priority-driven Collaborative Cancer Research Scheme
  • January 2019 - New article from the group published in Journal of Molecular Endocrinology

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  • December 2018 - Nigel Turner named School of Medical Sciences and UNSW Medicine Researcher of the Year
  • November 2018 - Sarah Hancock delivers oral presentation at the 4th Australian Lipids Meeting in Sydney
  • November 2018 - Hemna Govindaraju delivers oral presentation at AussieMit conference in Melbourne
  • October 2018 - Sarah Hancock delivers Rapid Fire oral presentation at the Translational Cancer Research Network Symposium in Sydney
  • October 2018 - Nature Communications paper from the group receives School of Medical Sciences 'Paper of the Month' award
  • October 2018 - Ghazal Sultani delivers poster flashtalk at Garvan Signalling Symposium in Sydney
  • October 2018 - Sarah Hancock delivers Mini Oral presentation at the Sydney Cancer Conference
  • September 2018 - New article from the group published in Biochemical and Biophysical Research Communications

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  • August 2018 - New article from the group published in Nature Communications

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  • July 2018 - Hemna Govindaraju commences her PhD studies
  • June 2018 - Louise Metcalfe receives the University Medal

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  • June 2018 - Nic Bentley and Menghan Liu graduate with PhD degrees

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  • December 2017 - Nic Bentley submits his PhD thesis

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  • October 2017- Brenna Osborne presents a poster at the Cell Symposia on Metabolic Disease Therapies, San Diego, supported by a Travel Grant from the Ian Potter Foundation

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  • October 2017 - Two new articles from the group published this month

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  • September 2017 - Brenna Osborne delivers oral presentation at the Australian Diabetes Society Meeting in Perth
  • July 2017 - Louise Metcalfe commences her PhD studies
  • May 2017 - Nic Bentley delivers an oral presentation at the Keystone Symposia on Aging and Mechanisms of Aging-related Diseases in Japan
  • March 2017 - Thomas Lakeland commence their PhD studies
  • March 2017 - Jayne Barbour submits her PhD thesis

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  • February 2017 - New funding received from the Diabetes Australia Research Program to investigate muscle lipids and insulin resistance
  • January 2017 - Menghan Liu submits her PhD thesis

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  • November 2016 - Two new project grants selected for funding by the National Health and Medical Research Council of Australia
  • November 2016 - Nic Bentley and Jayne Barbour give oral and poster presentations at the AussieMit Meeting, Sydney

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  • November 2016 - New article from the group published in BBA Mol Cell Biol Lipids

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  • October 2016 - Menghan Liu publishes first paper from her PhD in Cancer & Metabolism

 

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  • August 2016 - Brenna Osborne wins the Pincus Taft Young Investigator Award at the Australian Diabetes Society Meeting
  • July 2016 - Lake-Ee Quek publishes paper in Cancer & Metabolism       

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  • April 2016 - Azrah Samsudeen wins best poster presentation at the Gage Muscle Conference, Canberra

 

Social

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Team

Collaborators

Past Lab Members:

Dr Magda Montgomery, Research Fellow, Monash University

Dr Sanket Joshi, Research Fellow UNSW

Collaborators:

Professor David Sinclair, UNSW Sydney and Harvard Medical School, Boston

Professor Gregory Cooney, Charles Perkins Centre, University of Sydney

Associate Professor Todd Mitchell, University of Wollongong

 

Grants & Funding

Funding is provided by the National and Medical Health Research Council, the Australian Research Council and the Diabetes Australia Research Program.

Students

  • Ghazal Sultani (PhD)
  • Thomas Lakeland (PhD)
  • Louise Metcalfe (PhD)
  • Hemna Govindaraju (PhD)
  • Jesse Estoque (Honours)
  • Shelley Wang (Honours)

Please contact us for current opportunities for Honours and PhD students