Lipid Research Group

About us

Despite substantial advances, atherosclerosis remains a major cause of morbidity and premature death worldwide. To a large extent, this is the consequence of the high (and rising) prevalence of conditions such as a low level of the protective high density lipoproteins (HDL), insulin resistance and type 2 diabetes, and vascular dysfunction. There is compelling evidence of complex interrelationships between these that lead ultimately to the development of atherosclerosis and clinical cardiovascular diseases. The overall aim of our research program is to develop novel strategies for reducing cardiovascular disease and associated pathologies such as type 2 diabetes. Our research covers multiple topics including

  • The role of HDL in pancreatic beta cell function, in glucose disposal in skeletal muscle and in the development of type 2 diabetes
  • The cardioprotective properties of HDL apolipoproteins
  • Regulation of the development of cardiovascular disease by miRNAs
  • HDL functionality and cardiovascular disease
  • Identification of novel biomarkers that predict cardiovascular risk factors

Research Opportunities

There are opportunities for Honours and PhD students: contact Prof Kerry-Anne Rye for details of specific projects.



Sudichhya Shrestha - PhD