Emeritus Professor Nick Hawkins

Liu Q; Thoms JAI; Nunez AC; Huang Y; Knezevic K; Packham D; Poulos RC; Williams R; Beck D; Hawkins NJ; Ward RL; Wong JWH; Hesson LB; Sloane MA; Pimanda JE, 2018, 'Disruption of a 35 KB enhancer impairs CTCF binding and MLH1 expression in colorectal cells', Clinical Cancer Research, vol. 24, pp. 4602 - 4611, http://dx.doi.org/10.1158/1078-0432.CCR-17-3678

Domingo E; Camps C; Kaisaki PJ; Parsons MJ; Mouradov D; Pentony MM; Makino S; Palmieri M; Ward RL; Hawkins NJ; Gibbs P; Askautrud H; Oukrif D; Wang H; Wood J; Tomlinson E; Bark Y; Kaur K; Johnstone EC; Palles C; Church DN; Novelli M; Danielsen HE; Sherlock J; Kerr D; Kerr R; Sieber O; Taylor JC; Tomlinson I, 2018, 'Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series', The Lancet Gastroenterology and Hepatology, vol. 3, pp. 635 - 643, http://dx.doi.org/10.1016/S2468-1253(18)30117-1

Sakthianandeswaren A; Parsons MJ; Mouradov D; Mackinnon RN; Catimel B; Liu S; Palmieri M; Love C; Jorissen RN; Li S; Whitehead L; Putoczki TL; Preaudet A; Tsui C; Nowell CJ; Ward RL; Hawkins NJ; Desai J; Gibbs P; Ernst M; Street I; Buchert M; Sieber OM, 2018, 'MACROD2 haploinsufficiency impairs catalytic activity of PARP1 and promotes chromosome instability and growth of intestinal tumors', Cancer Discovery, vol. 8, pp. 988 - 1005, http://dx.doi.org/10.1158/2159-8290.CD-17-0909

Ma SSQ; Henry CE; Llamosas E; Higgins R; Daniels B; Hesson LB; Hawkins NJ; Ward RL; Ford CE, 2017, 'Validation of specificity of antibodies for immunohistochemistry: the case of ROR2', Virchows Archiv : an international journal of pathology, vol. 470, pp. 99 - 108, http://dx.doi.org/10.1007/s00428-016-2019-5

Kuroiwa-Trzmielina J; Wang F; Rapkins RW; Ward RL; Buchanan DD; Win AK; Clendenning M; Rosty C; Southey MC; Winship IM; Hopper JL; Jenkins MA; Olivier J; Hawkins NJ; Hitchins MP, 2016, 'SNP rs16906252C>T is an expression and methylation quantitative trait locus associated with an increased risk of developing MGMT-methylated colorectal cancer', Clinical Cancer Research, vol. 22, pp. 6266 - 6277, http://dx.doi.org/10.1158/1078-0432.CCR-15-2765

Ma SSQ; Henry CE; Llamosas E; Higgins R; Daniels B; Hesson LB; Hawkins NJ; Ward RL; Ford CE, 2016, 'Erratum to: Validation of specificity of antibodies for immunohistochemistry: the case of ROR2 (Virchows Archiv, (2016), 10.1007/s00428-016-2019-5)', Virchows Archiv, vol. 469, pp. 717, http://dx.doi.org/10.1007/s00428-016-2036-4

Hesson LB; Ng B; Zarzour P; Srivastava S; Kwok CT; Packham D; Nunez AC; Beck D; Ryan R; Dower A; Ford CE; Pimanda JE; Sloane MA; Hawkins NJ; Bourke MJ; Wong JWH; Ward RL, 2016, 'Integrated genetic, epigenetic, and transcriptional profiling identifies molecular pathways in the development of laterally spreading tumors', Molecular Cancer Research, vol. 14, pp. 1217 - 1228, http://dx.doi.org/10.1158/1541-7786.MCR-16-0175

Liu Q; Hesson LB; Nunez AC; Packham D; Hawkins NJ; Ward RL; Sloane MA, 2016, 'Pathogenic germline MCM9 variants are rare in Australian Lynch-like syndrome patients', Cancer Genetics, vol. 209, pp. 497 - 500, http://dx.doi.org/10.1016/j.cancergen.2016.10.001

Ma S; srivastava S; llamosas E; hawkins N; hesson L; ward R; Ford C, 2016, 'ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration.', BMC Cancer, vol. 16, http://dx.doi.org/10.1186/s12885-016-2576-7

He EYJ; Hawkins NJ; Mak G; Roncolato F; Goldstein D; Liauw W; Clingan P; Chin M; Ward RL, 2016, 'The impact of mismatch repair status in colorectal cancer on the decision to treat with adjuvant chemotherapy: An Australian population-based multicenter study', Oncologist, vol. 21, pp. 618 - 625, http://dx.doi.org/10.1634/theoncologist.2015-0530

Suraweera N; Mouradov D; Li S; Jorissen RN; Hampson D; Ghosh A; Sengupta N; Thaha M; Ahmed S; Kirwan M; Aleva F; Propper D; Feakins RM; Vulliamy T; Elwood NJ; Tian P; Ward RL; Hawkins NJ; Xu ZZ; Molloy PL; Jones IT; Croxford M; Gibbs P; Silver A; Sieber OM, 2016, 'Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer', Oncotarget, vol. 7, pp. 36474 - 36488, http://dx.doi.org/10.18632/oncotarget.9015

Polly P; Velan GM; Hawkins N, 2015, 'Development of Online Science Practical Lesson Resources to Enhance Student Learning in Phases 1 and 2 Medicine at UNSW Australia.', Proceedings of E-Learn: World Conference on E-Learning in Corporate, Government, Healthcare, and Higher Education 2015, pp. 1452 - 1458, http://www.editlib.org/pv/152202/

Wong V; Smith AJ; Hawkins NJ; Kumar RK; Young N; Kyaw M; Velan GM, 2015, 'Adaptive Tutorials Versus Web-Based Resources in Radiology: A Mixed Methods Comparison of Efficacy and Student Engagement', Academic Radiology, vol. 22, pp. 1299 - 1307, http://dx.doi.org/10.1016/j.acra.2015.07.002

Henry C; Quadir A; Hawkins NJ; Jary E; Llamosas E; Kumar D; Daniels B; Ward RL; Ford CE, 2015, 'Expression of the novel Wnt receptor ROR2 is increased in breast cancer and may regulate both β-catenin dependent and independent Wnt signalling', Journal of Cancer Research and Clinical Oncology, vol. 141, pp. 243 - 254, http://dx.doi.org/10.1007/s00432-014-1824-y

Yang J-L; Coleman K; Das M; Hawkins NJ, 2015, 'Integrated Career Development Learning and ePortfolios: Improving Student Self-efficacy in Employability Skills in an Undergraduate Science Course', International Journal of Adult, Community and Professional Learning, vol. 22, pp. 1 - 17, http://jialinyang.cgpublisher.com/product/pub.255/prod.57

Zarzour P; Boelen L; Luciani F; Beck D; Sakthianandeswaren A; Mouradov D; Sieber OM; Hawkins NJ; Hesson LB; Ward RL; Wong JWH, 2015, 'Single nucleotide polymorphism array profiling identifies distinct chromosomal aberration patterns across colorectal adenomas and carcinomas', Genes Chromosomes and Cancer, vol. 54, pp. 303 - 314, http://dx.doi.org/10.1002/gcc.22243

Scott GM; Hettiaratchi A; Salisbury E; Ward RL; Hawkins NJ, 2015, 'Institutional biobanking: An integral part of contemporary pathology practice', Pathology, vol. 47, pp. 4 - 6, http://dx.doi.org/10.1097/PAT.0000000000000185

Jorissen RN; Christie M; Mouradov D; Sakthianandeswaren A; Li S; Love C; Xu ZZ; Molloy PL; Jones IT; McLaughlin S; Ward RL; Hawkins NJ; Ruszkiewicz AR; Moore J; Burgess AW; Busam D; Zhao Q; Strausberg RL; Lipton L; Desai J; Gibbs P; Sieber OM, 2015, 'Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer', British Journal of Cancer, vol. 113, pp. 979 - 988, http://dx.doi.org/10.1038/bjc.2015.296

Xu H; Yan Y; Deb S; Rangasamy D; Germann M; Malaterre J; Eder NC; Ward RL; Hawkins NJ; Tothill RW; Chen L; Mortensen NJ; Fox SB; McKay MJ; Ramsay RG, 2014, 'Cohesin Rad21 Mediates Loss of Heterozygosity and Is Upregulated via Wnt Promoting Transcriptional Dysregulation in Gastrointestinal Tumors', Cell Reports, vol. 9, pp. 1781 - 1797, http://dx.doi.org/10.1016/j.celrep.2014.10.059

Meagher NS; Dean S; Koegelenberg A; Goode S; Caruso L; Pillai U; Marsh DJ; Brown S; Yip S; Walczak A; Kench JG; Horvath L; Nielsen S; Scott R; Hawkins NJ, 2014, 'INTEGRATING UNIVERSAL CONSENT FOR BIOBANKING AND HEALTH DATA COLLECTION WITHIN CLINICAL PATHWAYS IN NSW - THE BSN CONSENT PROJECT', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, vol. 10, pp. 22 - 23, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346343700063&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hesson LB; Sloane MA; Wong JWH; Nunez AC; Srivastava S; Ng B; Hawkins NJ; Bourke MJ; Ward RL, 2014, 'Altered promoter nucleosome positioning is an early event in gene silencing', Epigenetics, vol. 9, pp. 1422 - 1430, http://dx.doi.org/10.4161/15592294.2014.970077

Koegelenberg AM; Dean S; Meagher NS; Caruso L; Goode S; Pillai U; Marsh DJ; Brown S; Walczak A; Yip S; Kench JG; Horvath L; Nielsen S; Hawkins NJ; Scott R, 2014, 'CLOSING THE GAP BETWEEN RESEARCH, BIOBANKS AND CLINICAL PRACTICE: A 12 MONTH EXPLORATORY STUDY INTO DEVELOPING A STANDARD PRE-OPERATIVE MODEL FOR OBTAINING BIOBANK CONSENT', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, vol. 10, pp. 35 - 35, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344745100092&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Sloane MA; Wong JWH; Perera D; Nunez AC; Pimanda JE; Hawkins NJ; Sieber OM; Bourke MJ; Hesson LB; Ward RL, 2014, 'Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia', Epigenetics, vol. 9, pp. 1092 - 1100, http://dx.doi.org/10.4161/epi.29222

Wyld L; Smith S; Hawkins NJ; Long J; Ward RL, 2014, 'Introducing research initiatives into healthcare: What do doctors think?', Biopreservation and Biobanking, vol. 12, pp. 91 - 98, http://dx.doi.org/10.1089/bio.2013.0069

Deb S; Xu H; Tuynman J; George J; Yan Y; Li J; Ward RL; Mortensen N; Hawkins NJ; McKay MJ; Ramsay RG; Fox SB, 2014, 'RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas', British Journal of Cancer, vol. 110, pp. 1606 - 1613, http://dx.doi.org/10.1038/bjc.2014.31

Dewhurst SM; McGranahan N; Burrell RA; Rowan AJ; Grönroos E; Endesfelder D; Joshi T; Mouradov D; Gibbs P; Ward RL; Hawkins NJ; Szallasi Z; Sieber OM; Swanton C, 2014, 'Tolerance of whole- genome doubling propagates chromosomal instability and accelerates cancer genome evolution', Cancer Discovery, vol. 4, pp. 175 - 185, http://dx.doi.org/10.1158/2159-8290.CD-13-0285

Mouradov D; Domingo E; Gibbs P; Jorissen RN; Li S; Soo PY; Lipton L; Desai J; Danielsen HE; Oukrif D; Novelli M; Yau C; Holmes CC; Jones IT; McLaughlin S; Molloy P; Hawkins NJ; Ward R; Midgely R; Kerr D; Tomlinson IP; Sieber OM, 2013, 'Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations', American Journal of Gastroenterology, vol. 108, pp. 1785 - 1793, http://dx.doi.org/10.1038/ajg.2013.292

Day FL; Jorissen RN; Lipton L; Mouradov D; Sakthianandeswaren A; Christie M; Li S; Tsui C; Tie J; Desai J; Xu ZZ; Molloy P; Whitehall V; Leggett BA; Jones IT; McLaughlin S; Ward RL; Hawkins NJ; Ruszkiewicz AR; Moore J; Busam D; Zhao Q; Strausberg RL; Gibbs P; Sieber OM, 2013, 'PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in Colorectal cancer', Clinical Cancer Research, vol. 19, pp. 3285 - 3296, http://dx.doi.org/10.1158/1078-0432.CCR-12-3614

Webster LR; Provan PJ; Graham DJ; Byth K; Walker RL; Davis S; Salisbury EL; Morey AL; Ward RL; Hawkins NJ; Clarke CL; Meltzer PS; Balleine RL, 2013, 'Prohibitin expression is associated with high grade breast cancer but is not a driver of amplification at 17q21.33', Pathology, vol. 45, pp. 629 - 636, http://dx.doi.org/10.1097/PAT.0000000000000004

Metz AJ; Bourke MJ; Moss A; Dower A; Zarzour P; Hawkins NJ; Ward RL; Hesson L, 2013, 'A correlation of the endoscopic characteristics of colonic laterally spreading tumours (LSTs) with genetic alterations', European Journal of Gastroenterology and Hepatology, vol. 25, pp. 319 - 326, http://dx.doi.org/10.1097/MEG.0b013e32835b57e7

Fleming N; Jorissen RN; Mouradov D; Christie M; Sakthianandeswaren A; Palmieri M; Day F; Li S; Tsui C; Lipton L; Desai J; Jones IT; McLaughlin S; Ward RL; Hawkins NJ; Ruskiewicz A; Zhu HJ; Mariadason J; Burgess A; Busam D; Zhao Q; Strausberg R; Gibbs P; Sieber O, 2013, 'SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer', Cancer research, vol. 73, pp. 725 - 735, http://dx.doi.org/10.1158/0008-5472.CAN-12-2706

Christie M; Jorissen RN; Mouradov D; Sakthianandeswaren A; Li S; Day F; Tsui C; Lipton L; Desai J; Jones IT; McLaughlin S; Ward RL; Hawkins NJ; Ruskiewicz A; Burgess A; Busam D; Zhao Q; Strausberg R; Simpson AJ; Tomlinson IP; Gibbs P; Sieber O, 2013, 'Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/â-catenin signalling thresholds for tumourigenesis', Oncogene, vol. 32, pp. 4675 - 4682, http://dx.doi.org/10.1038/onc.2012.486

Ward RL; Hicks S; Hawkins NJ, 2013, 'Population based molecular screening for Lynch Syndrome – implications for personalized medicine', Journal of Clinical Oncology, vol. 31, pp. 2554 - 2562, http://dx.doi.org/10.1200/JCO.2012.46.8454

Hesson LB; Wong JWH; Sloane MA; Pimanda JE; Bourke MJ; Hawkins NJ; Ward RL, 2012, 'Nucleosome occupancy at unmethylated promoter CpG islands represents a novel mechanism of epigenetic gene silencing in cancer', CANCER RESEARCH, vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-990

Liu J; Hesson L; Meagher AP; Bourke MJ; Hawkins NJ; Rand KN; Molloy PL; Pimanda JE; Ward RL, 2012, 'Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa', CANCER PREVENTION RESEARCH, vol. 5, pp. 921 - 929, http://dx.doi.org/10.1158/1940-6207.CAPR-11-0577

Sigglekow ND; Pangon L; Brummer T; Molloy M; Hawkins NJ; Ward RL; Musgrove EA; Kohonen-Corish M, 2012, 'Mutated in Colorectal Cancer Protein Modulates the NFKB Pathway', Anticancer Research, vol. 32, pp. 73 - 80, http://www.ncbi.nlm.nih.gov/pubmed/22213290

Wong JJ; Hawkins NJ; Ward RL; Hitchins MP, 2011, 'Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer.', Modern Pathology, vol. 24, pp. 396 - 411, http://dx.doi.org/10.1038/modpathol.2010.212

Hicks S; Ward RL; Hawkins NJ, 2011, 'Immunohistochemistry for PMS2 and MSH6 alone can replace a four antibody panel for mismatch repair deficiency screening in colorectal adenocarcinoma: letter to the editor', Pathology, vol. 43, pp. 84 - 85, http://dx.doi.org/10.1097/PAT.0b013e3283410b26

Balasooriya CD; Di CSK; Hawkins NJ, 2010, 'The facilitation of collaborative learning; what works?', Higher Education Management and Policy, vol. 22, pp. 1 - 14

Kwok CK; Ward RL; Hawkins NJ; Hitchins MP, 2010, 'Detection of allelic imbalance in MLH1 expression by pyrosequencing serves as a tool for the identification of germline defects in Lynch syndrome', Familial Cancer, vol. 9, pp. 345 - 356, http://dx.doi.org/10.1007/s10689-009-9314-0

Packham D; Ward R; Lin VA; Hawkins NJ; Hitchins MP, 2009, 'Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers', Diagnostic Molecular Pathology, vol. 18, pp. 62 - 71, http://dx.doi.org/10.1097/PDM.0b013e318182af52

Carr N; Mahajan H; Tan K; Hawkins NJ; Ward RL, 2009, 'Serrated and non-serrated polyps of the colorectum: Their prevalence in an unselected case series and correlation of BRAF mutation analysis with the diagnosis of sessile serrated adenoma', Journal of Clinical Pathology, vol. 62, pp. 516 - 518, http://dx.doi.org/10.1136/jcp.2008.061960

Hawkins NJ; Lee J; Wong JJ; Kwok C; Ward RL; Hitchins MP, 2009, 'MGMT methylation is associated primarily with the germline C > T SNP (rs16906252) in colorectal cancer and normal colonic mucosa', Modern Pathology, vol. 22, pp. 1588 - 1599, http://dx.doi.org/10.1038/modpathol.2009.130

Webster L; Lee S; Ringland C; Morey AL; Hanby A; Morgan GJ; Byth K; Mote P; Provan P; Ellis I; R A; Lamoury GM; Ravdin P; Clarke CL; Ward RL; Balleine R; Hawkins NJ, 2008, 'Poor-Prognosis Estrogen Receptor - Positive Breast Cancer Identified by Histopathologic Subclassification', Clinical Cancer Research, vol. 14, pp. 6625 - 6633, http://dx.doi.org/10.1158/1078-0432.CCR-08-0701

Hitchins MP; Ap Lin V; Buckle AD; Cheong KF; Halani N; Ku S; Kwok C; Packham D; Suter CM; Meagher AP; Stirzaker C; Clark SJ; Hawkins NJ; Ward RL, 2007, 'Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer', Cancer research, vol. 67, pp. 9107 - 9116, http://dx.doi.org/10.1158/0008-5472.CAN-07-0869

Hettiaratchi A; Hawkins NJ; McKenzie GL; Ward RL; Hunt JE; Wakefield D; Di Girolamo N, 2007, 'The collagenase-1 (MMP-1) gene promoter polymorphism - 1607/2G is associated with favourable prognosis in patients with colorectal cancer', British Journal of Cancer, vol. 96, pp. 783 - 792, http://dx.doi.org/10.1038/sj.bjc.6603630

Hitchins MP; Wong JJ; Suthers GK; Suter CM; Martin DI; Hawkins NJ; Ward RL, 2007, 'Inheritance of a cancer-associated MLH1 germ-line epimutation', New England Journal of Medicine, vol. 356, pp. 697 - 705, http://dx.doi.org/10.1056/NEJMoa064522

Wong JJ; Hawkins NJ; Ward RL, 2007, 'Colorectal cancer: a model for epigenetic tumorigenesis', Gut, vol. 56, pp. 140 - 148, http://dx.doi.org/10.1136/gut.2005.088799

McClelland RJ; Hawkins N, 2006, 'Perspectives on the use and development of a broad range of e-books in higher education and their use in supporting virtual learning environments', Electronic Library, vol. 24, pp. 68 - 82, http://dx.doi.org/10.1108/02640470610649254

Hitchins MP; Suter CM; Wong J; Cheong K; Hawkins NJ; Leggett B; Scott R; Spigelman AD; Tomlinson IP; Martin DI; Ward RL, 2006, 'Germline epimutations of APC are not associated with inherited colorectal polyposis', Gut, vol. 55, pp. 586 - 587, http://dx.doi.org/10.1136/gut.2005.087486

Ward RL; Turner J; Hawkins NJ, 2006, 'Re: Ward et al. Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified. J Pathol 2005;207 : 377-384 - Authors` reply', Journal of Pathology, vol. 208, pp. 592 - 592, http://dx.doi.org/10.1002/path.1932

Colebatch A; Hitchins MP; Williams R; Meagher AP; Hawkins NJ; Ward RL, 2006, 'The role of MYH and microsatellite instability in the development of sporadic colorectal cancer', British Journal of Cancer, vol. 95, pp. 1239 - 1243, http://dx.doi.org/10.1038/sj.bjc.6603421

Hitchins MP; Williams RA; Cheong KF; Halani N; Lin V; Packham D; Ku S; Buckle AD; Hawkins NJ; Burn J, 2005, 'MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer', Gastroenterology, vol. 129, pp. 1392 - 1399, http://dx.doi.org/10.1053/j.gastro.2005.09.003

Ward RL; Turner J; Williams R; Pekarsky B; Packham D; Velickovic M; Meagher AP; O Connor TW; Hawkins NJ, 2005, 'Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified', Journal of Pathology, vol. 207, pp. 377 - 384, http://dx.doi.org/10.1002/path.1851

Kumar RK; Hawkins NJ; Harris PJ; Velan GM, 2004, 'Bridging the gap between the scientific and societal aspects of medical education', Journal of the International Association of Medical Science Educators, vol. 14, pp. 15 - 17

Ward RL; Williams R; Law MG; Hawkins NJ, 2004, 'The CpG island methylator phenotype is not associated with a personal or family history of cancer', Cancer research, vol. 64, pp. 7618 - 7621, http://dx.doi.org/10.1158/0008-5472.CAN-03-3978

Jass JR; Tomlinson I; Halford S; Aaltonen L; Hawkins N; Ward R, 2003, 'Re: Tomlinson et al. Does MSI-low exist. J Pathol 2002; 197: 6-13 (multiple letters)', Journal of Pathology, vol. 199, pp. 267 - 269, http://dx.doi.org/10.1002/path.1266

Norrie M; Hawkins NJ; Todd AV; Meagher AP; O Connor TW; Ward RL, 2003, 'Inactivation of p16INK4a by CpG hypermethylation is not a frequent event in colorectal cancer', Journal of Surgical Oncology, vol. 84, pp. 143 - 150, http://dx.doi.org/10.1002/jso.10310

Ward RL; Cheong K; Ku S; Meagher AP; O Connor TW; Hawkins NJ, 2003, 'Adverse Prognostic Effect of Methylation in Colorectal Cancer Is Reversed by Microsatellite Instability', Journal of Clinical Oncology, vol. 21, pp. 3729 - 3736, http://dx.doi.org/10.1200/JCO.2003.03.123

Brown DA; Ward RL; Buckhaults P; Liu T; Romans KE; Hawkins NJ; Bauskin AR; Kinzler KW; Vogelstein B; Breit SN, 2003, 'MIC 1 serum level and genotype: Associations with progress and prognosis of colorectal carcinoma', Clinical Cancer Research, vol. 9, pp. 2642 - 2650

Bariol CM; Hawkins NJ; Turner JJ; Meagher AP; Williams DB; Ward RL, 2003, 'Histopathological and clinical evaluation of serrated adenomas of the colon and rectum', Modern Pathology, vol. 16, pp. 417 - 423, http://dx.doi.org/10.1097/01.MP.0000068236.47471.DB

Liu T, 2003, 'Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum', Proceedings of the National Academy of Sciences of the United States of America, vol. 100, pp. 3410 - 3415, http://dx.doi.org/10.1073/pnas.0530278100

Bariol CM; Suter CM; Cheong K; Ky L; Meagher AP; Hawkins NJ; Ward RL, 2003, 'The relationship between hypomethylation and CpG island methylation in colorectal neoplasia', American Journal of Pathology, vol. 162, pp. 1361 - 1371, http://dx.doi.org/10.1016/S0002-9440(10)63932-6

Quinn E; Hawkins NJ; Suter CM; Yip YL; Ward RL, 2003, 'CD103+ intraepithelial lymphocytes- a unique population in microsatellite unstable sporadic colorectal cancer', European Journal of Cancer, vol. 39, pp. 469 - 475, http://dx.doi.org/10.1016/S0959-8049(02)00633-0

Ward RL; Hawkins NJ, 2002, 'Medical oncology', Medical Journal of Australia, vol. 176, pp. 25, http://dx.doi.org/10.5694/j.1326-5377.2002.tb04258.x

Ward RL; Hawkins NJ, 2002, 'Updates in Medicine - Medical Oncology', Medical Journal of Australia, vol. 25, pp. 25 - 25

Morey AL; Wanigesekera D; Hawkins NJ; Ward RL, 2002, 'C-kit mutations in gastrointestinal stromal tumours', Pathology, vol. 34, pp. 315 - 319, http://dx.doi.org/10.1080/00313020220147122

Norrie M; Hawkins NJ; Todd AV; Meagher AP; O Connor TW; Ward RL, 2002, 'The role hMLH1 methylation in the development of solitary and synchronous sporadic colorectal carcinomas', Diseases of the Colon and Rectum, vol. 45, pp. 674 - 680, http://dx.doi.org/10.1007/s10350-004-6266-1

Davenport MP; Ward RL; Hawkins NJ, 2002, 'The null oncogene hypothesis and protection from cancer', Journal of Medical Genetics, vol. 39, pp. 12 - 14

Tomlinson IP; Halford S; Aaltonen L; Hawkins NJ; Ward RL, 2002, 'Does MSI-low exist?', Journal of Pathology, vol. 197, pp. 6 - 13, http://dx.doi.org/10.1002/path.1071

Suter CM; Morgan GJ; Hanby A; Hawkins NJ; Ward RL, 2002, 'Clinicopathological correlates of GPIb-alpha expression in human breast cancers', Anticancer Research, vol. 22, pp. 1251 - 1256, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000177246300038&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Ward RL; Meldrum C; Williams R; Mokany E; Scott R; Turner J; Hawkins NJ; Burgess B; Groombridge C; Spigelman A, 2002, 'Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer', Journal of Cancer Research and Clinical Oncology, vol. 128, pp. 403 - 411, http://dx.doi.org/10.1007/s00432-002-0361-2

Hawkins NJ; Norrie M; Cheong K; Mokany E; Ku S; Meagher AP; O Connor TW; Ward RL, 2002, 'CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability', Gastroenterology, vol. 122, pp. 1376 - 1387, http://dx.doi.org/10.1053/gast.2002.32997

Ward RL; Hawkins NJ; Bariol C, 2002, 'The serrated neoplasia pathway', Pathology, vol. 34, pp. 548 - 555, http://dx.doi.org/10.1080/0031302021000035965

Halford S; Sasieni P; Rowan A; Wasan H; Bodmer W; Talbot I; Hawkins NJ; Ward RL; Tomlinson IP, 2002, 'Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait.', Cancer research, vol. 62, pp. 53 - 57

Jass JR, 2002, 'Progress in gastrointestinal pathology in the genetic era.', Pathology, vol. 34, pp. 493, https://www.ncbi.nlm.nih.gov/pubmed/12555986

Ward RL; Hawkins NJ, 2001, 'Checking the scoreboard: The impact of cancer genetics on clinical practice.', Internal Medicine Journal, vol. 31, pp. 249 - 253, http://dx.doi.org/10.1046/j.1445-5994.2001.00051.x

Andreyev HJ; Norman AR; Cunningham D; Oates J; DIx BR; lacopetta BJ; Young J; Walsh T; Ward RL; Hawkins NJ; Beranek M; Jandik P; Benamouzig R; Jullian E; Laurent-Puig P; Olswang S; Muller O; Hoffman I; Rabes HM; Zietz C; Troungas C; Valavanis C; Yuen ST; Ho JW; Croke CT; O Donoghue DP; Giaretti W; Rapallo A; Russo A; Bazan V; Tanaka M; Omura K; Azuma T; Ohkusa T; Fujimori T; Pauly M; Ono Y; Faber C; Glaesener R; de Goeji A; Arends JW; Andersen SN; Lovig T; Breivik J; Gaudernack G; Clausen OP; De Angelis P; Meling GI; Rognum TO; Smith R; Goh H; Font A; Rosell R; Sun XF; Zhang H; Benhattar J; Losi L; Lee JQ; Wang ST; Clarke PA; Bell S; Quirke P; Bubb VJ; Piris J; Cruickshank NR; Morton D; Fox JC; Al-Mulla F; Lees N; Hall CN; Snary D; Wilkinson K; Dillon D; Costa J; Senagore AJ; Pricolo VE; Finkelstein SD; Thebo JS; Halter SA; Wadler S; Malik S; Krtolica K; Urosevic N, 2001, 'Kirsten ras mutations in patients with colorectal cancer: the `RASCAL II` study.', British Journal of Cancer, vol. 85, pp. 692 - 696, http://dx.doi.org/10.1054/bjoc.2001.1964

Hawkins NJ; Tomlinson I; Meagher AP; Ward RL, 2001, 'Microsatellite-stable diploid carcinoma: A biologically distinct and aggressive subset of sporadic colorectal cancer', British Journal of Cancer, vol. 84, pp. 232 - 236, http://dx.doi.org/10.1054/bjoc.2000.1554

Ward RL; Meagher AP; Tomlinson I; O Connor TW; Norrie M; Wu R; Hawkins NJ, 2001, 'Microsatellite instability and the clinicopathological features of sporadic colorectal cancer', Gut, vol. 48, pp. 821 - 829, http://dx.doi.org/10.1136/gut.48.6.821

Hawkins NJ; Ward RL, 2001, 'Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas', Journal of the National Cancer Institute, vol. 93, pp. 1307 - 1313, http://dx.doi.org/10.1093/jnci/93.17.1307

Hawkins NJ; Tomlinson I; Ward RL, 2001, 'Biological significance of microsatellite instability-low (MSI-L) status in colorectal tumors', American Journal of Pathology, vol. 158, pp. 780 - 781, http://dx.doi.org/10.1016/S0002-9440(10)64020-5

Ward RL; Sheehan C; Norrie M; Applegate TL; Fuery CJ; Impey H; Hawkins NJ; Todd AV, 2000, 'Factors influencing the detection of mutant K-ras in the serum of patients with colorectal cancer', Annals of the New York Academy of Sciences, vol. 906, pp. 17 - 18, http://dx.doi.org/10.1111/j.1749-6632.2000.tb06583.x

Fuery CJ; Impey H; Roberts NK; Applegate TL; Ward RL; Hawkins NJ; Sheehan C; O Grady R; Todd AV, 2000, 'Detection of rare mutant alleles by restriction endonuclease-mediated selective-PCR: assay design and optimization', Clinical Chemistry, vol. 46, pp. 620 - 624

Ward RL; Packham D; Smythe AM; Anderson-Stewart P; Kitchen NA; Phillips P; Gray PP; Prabakaran K; Freund J; Fullham M; Rule M; Dalley D; Meagher AP; Hawkins NJ; Smith G, 2000, 'Phase I clinical trial of the chimeric monoclonal antibody (c30.6) in patients with metastatic colorectal cancer', Clinical Cancer Research, vol. 6, pp. 4674 - 4683, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000166160200013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Hawkins NJ; Gorman P; Tomlinson IP; Bullpitt P; Ward RL, 2000, 'Colorectal carcinomas arising in the hyperplastic polyposis syndrome progress through the chromosomal instability pathway', American Journal of Pathology, vol. 157, pp. 385 - 392, http://dx.doi.org/10.1016/S0002-9440(10)64551-8

Coomber DW; Hawkins NJ; Clark MA; Ward RL, 1999, 'Generation of anti-p53 Fab fragments from individuals with colorectal cancer using phage display', Journal of Immunology, vol. 163, pp. 2276 - 2283

Ward RL; Hawkins NJ; Coomber DW; Disis ML, 1999, 'Antibody immunity to the HER-2/neu oncogenic protein in patients with colorectal cancer', Human Immunology, vol. 60, pp. 510 - 515, http://dx.doi.org/10.1016/S0198-8859(99)00003-8

Chamberlain NL; Ward RL; Hawkins NJ, 1999, 'Clinicopathological significance of erbB-2 expression in colorectal cancer', Oncology Reports, vol. 6, pp. 527 - 531

Zahra DG; Vancov A; Dunn JM; Hawkins NJ; Ward RL, 1999, 'Selectable in vivo recombination to increase antibody library size - an improved phage display vector system', Gene, vol. 227, pp. 49 - 54, http://dx.doi.org/10.1016/S0378-1119(98)00593-9

Yip YL; Hawkins NJ; Smith G; Ward RL, 1999, 'Biodistribution of filamentous phage-Fab in nude mice', Journal of Immunological Methods, vol. 225, pp. 171 - 178, http://dx.doi.org/10.1016/S0022-1759(99)00044-7

Hawkins NJ; Ward RL, 1998, 'Phage display: evolving proteins in vitro.', Today's Life Science, vol. 10, pp. 32 - 36

Ward RL; Hawkins NJ; O Grady R; Sheehan C; O Connor TW; Impey H; Furey C; Todd AV; Roberts N, 1998, 'Restriction endonuclease-mediated selective polymerase chain reaction. A novel assay for the detection of K-ras mutations in clinical samples.', American Journal of Pathology, vol. 153, pp. 373 - 379, http://dx.doi.org/10.1016/S0002-9440(10)65581-2

Coomber DW; Hawkins NJ; Dalley D; Ward RL, 1998, 'The significance of anti-sialyl-Tn antibodies in patients with colorectal or breast cancer', Neoplasma, vol. 45, pp. 12 - 16, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000072742800003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Ward RL; Hawkins NJ; Smith G, 1997, 'Antibody therapy in solid tumours; lessons from the clinic', Cancer Treatment Reviews, pp. 305 - 319

Hawkins NJ; Lees J; Ward RL, 1997, 'Detection of apoptosis in colorectal carcinoma Bylight microscopy and in-situ end-laBelling', Analytical and Quantitative Cytology and Histology, vol. 19, pp. 227 - 232

Hawkins NJ; Ward RL; Smith L, 1997, 'The images of disease project; a computer-Based aid to the teaching of pathology', Medical Teacher, vol. 19, pp. 45 - 50, http://dx.doi.org/10.3109/01421599709019347

Ward RL; Todd AV; Santiago FS; O Connor TW; Hawkins NJ, 1997, 'Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis', Cancer, vol. 79, pp. 1106 - 1113, http://dx.doi.org/10.1002/(SICI)1097-0142(19970315)79:6<1106::AID-CNCR8>3.0.CO;2-D

Santiago FS; Todd AV; Hawkins NJ; Ward RL, 1997, 'Detection of K-ras point mutation by enriched PCR-colorimetric plate assay', Molecular and Cellular Probes, vol. 11, pp. 33 - 38, http://dx.doi.org/10.1006/mcpr.1996.0073

Hawkins NJ; Lees J; Hargrave R; O Connor TW; Meagher AP; Ward RL, 1997, 'Pathological and genetic correlates of apoptosis in the progression of colorectal neoplasia', Tumor Biology, vol. 18, pp. 146 - 156, http://dx.doi.org/10.1159/000218025

Yip YL; Hawkins NJ; Clark MA; Ward RL, 1997, 'Evaluation of different lymphoid tissue sources for the construction of human immunoglobulin gene libraries', Immunotechnology, vol. 3, pp. 195 - 203, http://dx.doi.org/10.1016/S1380-2933(97)00013-4

Clark MA; Hawkins NJ; Papaioannou A; Fiddes RJ; Ward RL, 1997, 'Isolation of human anti-c-erBB-2 FaBs from a lymph node-derived phage display liBrary', Clinical and Experimental Immunology, vol. 109, pp. 166 - 174, http://dx.doi.org/10.1046/j.1365-2249.1997.4161316.x

Clark MA; Hammond F; Papaioannou A; Hawkins NJ; Ward RL, 1997, 'Regulation and expression of human Fabs under the control of the Escherichia coli arabinose promoter PBAD', Immunotechnology, vol. 3, pp. 217 - 226, http://dx.doi.org/10.1016/S1380-2933(97)00016-X

Hawkins NJ; Ward RL; Smith G, 1997, 'Unconjugated antibodies for cancer therapy: lessons from the clinic', Cancer Treatment Reviews, vol. 23, pp. 305 - 319, http://dx.doi.org/10.1016/S0305-7372(97)90030-X

Pells S; Divjak M; Romanowski P; Impey H; Hawkins NJ; Clarke AR; Hooper ML; Williamson DJ, 1997, 'Developmentally-regulated expression of murine K-ras isoforms', Oncogene, vol. 15, pp. 1781 - 1786, http://dx.doi.org/10.1038/sj.onc.1201354

Coomber DW; Hawkins NJ; Clark MA; Meagher AP; Ward RL, 1996, 'Characterisation and clinicopathological correlates of serum anti-p53 antibodies in breast and colon cancer', Journal of Cancer Research and Clinical Oncology, vol. 122, pp. 757 - 762, http://dx.doi.org/10.1007/BF01209124

Dolnikov A; Ward RL; Hawkins NJ; Symonds G, 1996, 'Apoptosis in v-myc transformation of myelomonocytic cells and its modulation by CSF-1', Oncogene, vol. 12, pp. 1189 - 1198

Hawkins NJ; Lees J; Kearney PP; Clark MA; Golovsky D; Ward RL, 1996, 'Biological properties of renal oncocytoma cells in culture', Urologia Internationalis, vol. 56, pp. 69 - 74, http://dx.doi.org/10.1159/000282814

Ward RL; Clark MA; Lees J; Hawkins NJ, 1996, 'Retrieval of human antibodies from phage-display libraries using enzymatic elution', Journal of Immunological Methods, vol. 189, pp. 73 - 82, http://dx.doi.org/10.1016/0022-1759(95)00231-6

Dolnikov A; Yi S; Hawkins NJ; Ward RL; Symonds G, 1995, 'Transformation by v-erb-B: induction of apoptosis is abrogated in a myeloid cell line', International Journal of Oncology, vol. 6, pp. 633 - 638

Ward RL; Santiago FS; Hawkins NJ; Coomber DW; O Connor TW; Todd AV, 1995, 'A rapid PCR ELISA for the detection of activates K-ras in colorectal cancer', Journal of Clinical Pathology, vol. 48, pp. 273 - 277, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995RZ58000009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Hawkins NJ; Ward RL; Wakefield D, 1994, 'Cytokine-mediated induction of HLA antigen expression on human glomerular mesangial cells', Cellular Immunology, vol. 155, pp. 493 - 500, http://dx.doi.org/10.1006/cimm.1994.1141

Ward RL; Hawkins NJ, 1993, 'Recombinant antibodies: back to the future', The Australian and New Zealand Journal of Medicine, vol. 23, pp. 393 - 403, http://dx.doi.org/10.1111/j.1445-5994.1993.tb01441.x

Ward RL; Hawkins NJ; Wakefield D; Atkinson K; Biggs J, 1993, 'Production of a functional single-chain Fv fragment from the pan-leukocyte antibody WM65 using splicing by asymmetric PCR', British Journal Haematology, vol. 21, pp. 660 - 664, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993MW61000011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Wakefield D; Hawkins NJ, 1992, 'Sarcoidosis: Current concepts of pathogenesis and treatment.', Saudi Medical Journal, vol. 13, pp. 283 - 290

Hawkins NJ; Wakefield D; Charlesworth JA, 1990, 'The role of mesangial cells in glomerular pathology', Pathology, vol. 22, pp. 24 - 32, http://dx.doi.org/10.3109/00313029009061422

Hawkins NJ; Wakefield D; Charlesworth J, 1990, 'The mesangial cell', Pathology, vol. 22, pp. 24 - 32

Clark MA; Hawkins NJ; Ward RL, 1997, 'Selection and assay of recombinant antibodies against colorectal tumour antigens', in 9th Lorne Cancer Conference, 9th Lorne Cancer Conference, Lorne, Victoria, pp. 1102 - 1102, presented at 9th Lorne Cancer Conference, Lorne, Victoria, 13 February 1997 - 16 February 1997

Zahra DG; Hawkins NJ; Vancov A; Ward RL, 1997, 'An in vivo recombination strategy using 1oxP-cre to generate large phage display antiBody repertoires', in 9th Lorne Cancer Conference, 9th Lorne Cancer Conference, Lorne, Victoria, pp. E3 - E3, presented at 9th Lorne Cancer Conference, Lorne, Victoria, 13 February 1997 - 16 February 1997

Hawkins NJ; Hewson LD; Hughes CS; Velan GM, 1996, 'The use of the world-wide web in the support of tutorials in Pathology at remote sites', in Virtual Univeristy Symposium, Virtual University Symposium, Melbourne, presented at Virtual University Symposium, Melbourne, 21 November 1996 - 22 November 1996

Ward RL; Clark MA; Papaioannou A; Hawkins NJ, 1996, 'Generation of anti-tumour antibodies using phage display.', in IBC international conference on Antibody engineering, IBC international conference on Antibody engineering, San Diego, California, USA, pp. 211 - 219, presented at IBC international conference on Antibody engineering, San Diego, California, USA, -

Liu J; Hesson LB; Meagher AP; Bourke MJ; Hawkins NJ; Rand KN; Molloy PL; Pimanda JE; Ward RL, 2012, 'Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-3125