Professor Kenneth Williams

Tegeder I; Williams K; Geisslinger G, 2003, 'Metabolic Chiral Inversion of 2-Arylpropionic Acids', in Stereochemical Aspects of Drug Action and Disposition, Springer Berlin Heidelberg, pp. 341 - 354, http://dx.doi.org/10.1007/978-3-642-55842-9_14

Day RO; Quinn DI; March LM; Graham GG; Williams KM, 2000, 'Rheumatoid arthritis. New Frontiers in pathogenesis and treatment', in NSAIDs and analgesics, edn. Original, Oxford University Press, Oxford, England, pp. 307 - 328

Bachmeier CJ; Handel ML; Conaghan PG; Williams KM; Graham GG; Brooks PM; Day RO, 1999, 'Disease-modifying antirheumatic drugs', in Nijkamp FP; Parnham MJ (ed.), Principles of Immunopharmacology, edn. 3, Birkhauser Verlag (Springer), Basel, Switzerland, pp. 379 - 403

Bachmeier CJ; Handel ML; Conaghan PG; Williams KM; Graham GG; Brooks PM; Day RO, 1998, 'Disease Modifying antirheumatic drugs', in Textbook of Immunopharmacology, edn. 3, Burkhauser, Basel, Switzerland, pp. 183 - 190, http://dx.doi.org/10.1097/00002281-199705000-00003

Graham GG; Milligan MK; Day RO; Williams KM; Ziegler JB, 1998, 'Therapeutic considerations from pharmacokinetics and metabolism: ibuprofen and paracetamol', in Rainsford KD; Powanda MC (ed.), Safety and Efficacy of non-prescription (OTC) analgesics and NSAIDs, Kluwer Academic Publishers, Dordrecht, pp. 77 - 92, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000081416000006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Graham GG; Milligan MK; Day RO; Williams KM; Zeig , 1997, 'Therapeutic considerations from pharmacokinetics and metabolism: ibuprofen and paracetamol', in In: `Safety and efficacy of non-prescription (OTC) analgesics, edn. Original, Kluwer Academic Publishers, Great Britain, pp. 77 - 92

Vesey G; Ashbolt NJ; Wallner G; Dorsch R; Williams KM; Veal DA, 1995, 'Assessing cryptosporidium parvum oocyst viability with fluorescent in situ hybridization using ribosomal RNA probes and flow cytometry', in Protozoan parasites and water, edn. Original, Royal Society of Chemistry, Cambridge, pp. 133 - 138

Abdel Shaheed C; Carland JE; Graham GG; Stocker SL; Smith G; Hicks M; Williams KM; Furlong T; Macdonald P; Greenfield JR; Smith FC; Chowdhury G; Day RO, 2019, 'Is the use of metformin in patients undergoing dialysis hazardous for life? A systematic review of the safety of metformin in patients undergoing dialysis', British Journal of Clinical Pharmacology, vol. 85, pp. 2772 - 2783, http://dx.doi.org/10.1111/bcp.14107

Kamel B; Williams KM; Graham GG; Norris RLG; Stocker SL; Carland JE; Pile KD; Day RO, 2019, 'Determination of febuxostat in human plasma by high performance liquid chromatography (HPLC) with fluorescence-detection', Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 1126-1127, http://dx.doi.org/10.1016/j.jchromb.2019.121764

Day RO; Lau W; Stocker SL; Aung E; Coleshill MJ; Schulz M; Bechara J; Carland JE; Graham GG; Williams KM; McLachlan AJ, 2019, 'Management of gout in older people', Journal of Pharmacy Practice and Research, vol. 49, pp. 90 - 97, http://dx.doi.org/10.1002/jppr.1511

Kumar SS; McManus H; Radovich T; Greenfield JR; Viardot A; Williams KM; Cronin P; Day RO, 2018, 'Interrogation of a longitudinal, national pharmacy claims dataset to explore factors that predict the need for add-on therapy in older and socioeconomically disadvantaged Australians with type 2 diabetes mellitus patients (T2DM)', European Journal of Clinical Pharmacology, vol. 74, pp. 1327 - 1332, http://dx.doi.org/10.1007/s00228-018-2506-5

Day R; Kamel B; Graham GG; Williams KM; Stocker SL; Carland JE; Pile KD; Mcguigan LE; Portek IJ; Mcgill NW, 2018, 'A Multicentre Open-Label Pharmacokinetic-Pharmacodynamic Study of Febuxostat in Patients with Chronic Gout', Proceedings for Annual Meeting of The Japanese Pharmacological Society, vol. WCP2018, http://dx.doi.org/10.1254/jpssuppl.wcp2018.0_po1-11-12

Day RO; Frensham LJ; Nguyen AD; Baysari MT; Aung E; Lau AYS; Zwar N; Reath J; Laba T; Li L; McLachlan A; Runciman WB; Buchbinder R; Clay-Williams R; Coiera E; Braithwaite J; McNeil HP; Hunter DJ; Pile KJ; Portek I; Williams KM; Westbrook JI, 2017, 'Effectiveness of an electronic patient-centred self-management tool for gout sufferers: A cluster randomised controlled trail protocol', BMJ Open, vol. 7, http://dx.doi.org/10.1136/bmjopen-2017-017281

Duong JK; Kroonen MYAM; Kumar SS; Heerspink HL; Kirkpatrick CM; Graham GG; Williams KM; Day RO, 2017, 'A dosing algorithm for metformin based on the relationships between exposure and renal clearance of metformin in patients with varying degrees of kidney function', European Journal of Clinical Pharmacology, vol. 73, pp. 981 - 990, http://dx.doi.org/10.1007/s00228-017-2251-1

Kamel B; Graham GG; Williams KM; Pile KD; Day RO, 2017, 'Clinical Pharmacokinetics and Pharmacodynamics of Febuxostat', Clinical Pharmacokinetics, vol. 56, pp. 459 - 475, http://dx.doi.org/10.1007/s40262-016-0466-4

Day RO; Kannangara DRW; Stocker SL; Carland JE; Williams KM; Graham GG, 2017, 'Allopurinol: insights from studies of dose–response relationships', Expert Opinion on Drug Metabolism and Toxicology, vol. 13, pp. 449 - 462, http://dx.doi.org/10.1080/17425255.2017.1269745

Kannangara DRW; Graham GG; Wright DFB; Stocker SL; Portek I; Pile KD; Barclay ML; Williams KM; Stamp LK; Day RO, 2017, 'Individualising the dose of allopurinol in patients with gout', British Journal of Clinical Pharmacology, vol. 83, pp. 2015 - 2026, http://dx.doi.org/10.1111/bcp.13307

Moon J; Kumar SS; Graham GG; Baysari MT; Williams KM; Chen W; Viardot A; Greenfield JR; Day RO, 2016, 'Trends in metformin utilisation and dose appropriateness in Australia', European Journal of Clinical Pharmacology, vol. 72, pp. 1489 - 1496, http://dx.doi.org/10.1007/s00228-016-2117-y

Smith FC; Kumar SS; Furlong TJ; Gangaram SV; Greenfield JR; Stocker SL; Graham GG; Williams KM; Day RO, 2016, 'Pharmacokinetics of Metformin in Patients Receiving Regular Hemodiafiltration', American Journal of Kidney Diseases, vol. 68, pp. 990 - 992, http://dx.doi.org/10.1053/j.ajkd.2016.08.017

Kannangara DRW; Graham GG; Williams KM; Day RO, 2016, 'Effect of xanthine oxidase inhibitors on the renal clearance of uric acid and creatinine', Clinical Rheumatology, vol. 35, pp. 2375 - 2376, http://dx.doi.org/10.1007/s10067-015-3165-x

Kannangara DRW; Phipps-Green AJ; Dalbeth N; Stamp LK; Williams KM; Graham GG; Day RO; Merriman TR, 2016, 'Hyperuricaemia: Contributions of urate transporter ABCG2 and the fractional renal clearance of urate', Annals of the Rheumatic Diseases, vol. 75, pp. 1363 - 1366, http://dx.doi.org/10.1136/annrheumdis-2015-208111

Rasheed H; McKinney C; Stamp LK; Dalbeth N; Topless RK; Day R; Kannangara D; Williams K; Smith M; Janssen M; Jansen TL; Joosten LA; Radstake TR; Riches PL; Tausche AK; Lioté F; Lu L; Stahl EA; Choi HK; So A; Merriman TR, 2016, 'The toll-like receptor 4 (TLR4) variant rs2149356 and risk of gout in European and polynesian sample sets', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0147939

Martinello M; Schteinman A; Alavi M; Williams K; Dore GJ; Day R; Matthews GV, 2016, 'The impact of ribavirin plasma concentration on the efficacy of the interferon-sparing regimen, sofosbuvir and ribavirin', ANTIVIRAL THERAPY, vol. 21, pp. 127 - 132, http://dx.doi.org/10.3851/IMP2984

Vaccher S; Kannangara DRW; Baysari MT; Reath J; Zwar N; Williams KM; Day RO, 2016, 'Barriers to care in gout: From prescriber to patient', Journal of Rheumatology, vol. 43, pp. 144 - 149, http://dx.doi.org/10.3899/jrheum.150607

Day RO; Kamel B; Kannangara DRW; Williams KM; Graham GG, 2016, 'Xanthine oxidoreductase and its inhibitors: Relevance for gout', Clinical Science, vol. 130, pp. 2167 - 2180, http://dx.doi.org/10.1042/CS20160010

Chung WH; Chang WC; Stocker SL; Juo CG; Graham GG; Lee MHH; Williams KM; Tian YC; Juan KC; Wu YJJ; Yang CH; Chang CJ; Lin YJ; Day RO; Hung SI, 2015, 'Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: The impact of renal insufficiency, high plasma levels of oxypurinol and granulysin', Annals of the Rheumatic Diseases, vol. 74, pp. 2157 - 2164, http://dx.doi.org/10.1136/annrheumdis-2014-205577

McKinney C; Stamp LK; Dalbeth N; Topless RK; Day RO; Kannangara DRW; Williams KM; Janssen M; Jansen TL; Joosten LA; Radstake TR; Riches PL; Tausche AK; Lioté F; So A; Merriman TR, 2015, 'Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout', Arthritis Research and Therapy, vol. 17, http://dx.doi.org/10.1186/s13075-015-0802-3

Merriman TR; Stamp LK; Dalbeth N; Topless R; Day R; Kannangara D; Williams K; Janssen M; Jansen T; Joosten LA; Radstake T; Riches PL; Tausche A-K; Liote F; So A; McKinney C, 2015, 'Epistatic Interaction of Functional Inflammasome Genetic Variants in Determining the Risk of Gout', ARTHRITIS & RHEUMATOLOGY, vol. 67, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000370860204715&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hmar RC; Kannangara DRW; Ramasamy SN; Baysari MT; Williams KM; Day RO, 2015, 'Understanding and improving the use of allopurinol in a teaching hospital', Internal Medicine Journal, vol. 45, pp. 383 - 390, http://dx.doi.org/10.1111/imj.12701

Duong JK; Kumar SS; Furlong TJ; Kirkpatrick CM; Graham GG; Greenfield JR; Williams KM; Day RO, 2015, 'The pharmacokinetics of metformin and concentrations of haemoglobin A1C and lactate in Indigenous and non-Indigenous Australians with type 2 diabetes mellitus', British Journal of Clinical Pharmacology, vol. 79, pp. 617 - 623, http://dx.doi.org/10.1111/bcp.12525

Ghosh D; Williams KM; Graham GG; Nair P; Buscher H; Day RO, 2014, 'Multiple episodes of aspirin overdose in an individual patient: A case report', Journal of Medical Case Reports, vol. 8, pp. 1 - 5, http://dx.doi.org/10.1186/1752-1947-8-374

Rasheed H; Topless R; Day R; Kannangara D; Williams K; Bradbury L; Brown M; Hill C; Lester S; Rischmueller M; Smith M; Andres M; Bardin T; Doherty M; Janssen M; Jansen T; Joosten L; Perez-Ruiz F; Radstake T; Riches PL; Roddy E; Tausche A-K; Stamp LK; Dalbeth N; Liote F; So A; McKinney C; Merriman TR, 2014, 'Association of the Toll-like Receptor 4 (TLR4) Gene with Gout.', ARTHRITIS & RHEUMATOLOGY, vol. 66, pp. S1294 - S1295, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344384906196&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Kannangara DRW; Graham GG; Williams KM; Day RO, 2014, 'Hypouricemic effects of prednisone and allopurinol: An uneven playing field?', Canadian Journal of Cardiology, vol. 30, pp. 376.e1, http://dx.doi.org/10.1016/j.cjca.2013.04.015

Kannangara DRW; Ramasamy SN; Ray JE; Jones G; Graham GG; Williams KM; Day RO, 2013, 'An audit of a therapeutic drug monitoring service for allopurinol therapy', Therapeutic Drug Monitoring, vol. 35, pp. 863 - 866, http://dx.doi.org/10.1097/FTD.0b013e318299920a

Ramasamy SN; Korb-Wells CS; Kannangara DRW; Smith MWH; Wang N; Roberts DM; Graham GG; Williams KM; Day RO, 2013, 'Allopurinol hypersensitivity: A systematic review of all published cases, 1950-2012', Drug Safety, vol. 36, pp. 953 - 980, http://dx.doi.org/10.1007/s40264-013-0084-0

Day R; Lee H; Graham G; Williams K, 2013, 'Benzbromarone: Availability for general prescribing in New Zealand (a response to letters by Dr Lance Gravatt on benzbromarone)', New Zealand Medical Journal, vol. 126, pp. 124 - 126

Wong C; Kumar SS; Graham GG; Begg EJ; Chin P; Brett J; Ray J; Marriott D; Williams KM; Day RO, 2013, 'Comparing dose prediction software used to manage gentamicin dosing', Internal Medicine Journal, vol. 43, pp. 519 - 525, http://dx.doi.org/10.1111/imj.12067

Lee M-H; Stocker S; Williams KM; Day RO, 2013, 'HLA-B*5801 should be used to screen for risk of Stevens-Johnson Syndrome (SJS) in family members of Han-Chinese patients commencing allopurinol therapy', Journal of Rheumatology, vol. 40, pp. 96 - 97, http://dx.doi.org/10.3899/jrheum.120803

Brett J; Chong O; Graham GG; Ray J; Marriott D; Williams KM; Day RO, 2013, 'Antifungal Use and Therapeutic Monitoring of Plasma Concentrations of Itraconazole in Heart and Lung Transplantation Patients.', Therapeutic Drug Monitoring, vol. 35, pp. 133 - 136, http://dx.doi.org/10.1097/FTD.0b013e318275fe69

Lee M-H; Stocker S; Anderson JM; Phillips EJ; Nolan DL; Williams KM; Graham GG; Sullivan JR; Day RO, 2012, 'Initiating allopurinol therapy: Do we need to know the patient's human leucocyte antigen status?', Internal Medicine Journal, vol. 42, pp. 411 - 416, http://dx.doi.org/10.1111/j.1445-5994.2011.02567.x

Duong JK; Roberts DM; Furlong TJ; Kumar SS; Greenfield JR; Kirkpatrick CM; Graham GG; Williams KM; Day RO, 2012, 'Metformin therapy in patients with chronic kidney disease', Diabetes Obesity and Metabolism, vol. 14, pp. 963 - 965, http://dx.doi.org/10.1111/j.1463-1326.2012.01617.x

Kannangara DRW; Ramasamy SN; Indraratna P; Stocker S; Graham GG; Jones G; Portek I; Williams KM; Day RO, 2012, 'Fractional clearance of urate: Validation of measurement in spot urine samples in healthy subjects and gouty patients', Arthritis Research and Therapy, vol. 14, pp. R189 - R197, http://dx.doi.org/10.1186/ar4020

Kannangara D; Roberts DM; Furlong TJ; Graham GG; Williams K; Day RO, 2012, 'Oxypurinol, allopurinol and allopurinol-1-riboside in plasma following an acute overdose of allopurinol in a patient with advanced chronic kidney disease', British Journal of Clinical Pharmacology, vol. 73, pp. 828 - 829, http://dx.doi.org/10.1111/j.1365-2125.2011.04147.x

Stocker S; Mclachlan AJ; Savic RM; Kirkpatrick CM; Graham GG; Williams KM; Day RO, 2012, 'The pharmacokinetics of oxypurinol in people with gout', British Journal of Clinical Pharacology, vol. 74, pp. 477 - 489, http://dx.doi.org/10.1111/j.1365-2125.2012.04207.x

Wang N; Lipworth WL; Ritchie JE; Williams K; Day RO, 2011, 'Eliciting views of Australian pharmaceutical industry employees on collaboration and the concept of Quality Use of Medicines', Internal Medicine Journal, vol. 41, pp. 314 - 320, http://dx.doi.org/10.1111/j.1445-5994.2010.02239.x

Graham GG; Punt J; Manit A; Day RO; Doogue MP; Duong JK; Furlong TJ; Greenfield JR; Greenup L; Carl m kirkpatrick CM; Ray J; Timmins P; Williams KM, 2011, 'Clinical pharmacokinetics of metforim', Clinical Pharmacokinetics, vol. 50, pp. 81 - 98, http://dx.doi.org/10.2165/11534750-000000000-00000

Ng DY; Stocker SL; Graham GG; Williams KM; Day RO, 2011, 'Lack of effect of hydrochlorothiazide and low-dose aspirin on the renal clearance of urate and oxypurinol after a single dose of allopurinol in normal volunteers', European Journal of Clinical Pharmacology, vol. 67, pp. 709 - 713, http://dx.doi.org/10.1007/s00228-010-0963-6

Stocker SL; Graham GG; McLachlan AJ; Williams K; Day RO, 2011, 'Pharmacokinetic and Pharmacodynamic interaction between allopurinol and probenecid in patients with gout', Journal of Rheumatology, vol. 38, pp. 904 - 910, http://dx.doi.org/10.3899/jrheum.101160

Milder T; Lipworth WL; Williams KM; Ritchie JE; Day RO, 2011, '"It looks after me": how older patients make decisions about analgesics for osteoarthritis.', Arthritis Care and Research, vol. 63, pp. 1280 - 1286, http://dx.doi.org/10.1002/acr.20514

Milder T; Williams K; Ritchie JE; Lipworth WL; Day RO, 2011, 'Use of NSAIDs for osteoarthritis amongst older-aged primary care patients: Engagement with information and perceptions of risk', Age and Ageing, vol. 40, pp. 254 - 259, http://dx.doi.org/10.1093/ageing/afq160

Abdul M; Jiang XM; Williams KM; Day RO; Roufogalis B; Liauw WS; Xu H; Matthias A; Lehmann RP; McLachlan AJ, 2010, 'Pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects', British Journal of Clinical Pharmacology, vol. 69, pp. 508 - 515, http://dx.doi.org/10.1111/j.1365-2125.2010.03620.x

Indraratna P; Stocker SL; Williams KM; Graham GG; Jones G; Day RO, 2010, 'A proposal for identifying the low renal uric acid clearance phenotype', Arthritis Research and Therapy, vol. 12, pp. 149 - 151, http://dx.doi.org/10.1186/ar3191

Stocker S; Franklin M; Anderson JM; Pillans PI; Williams K; McLachlan AJ; Day RO; taylor P, 2010, 'Measurement of urinary oxypurinol by high performance liquid chromatography-tandem mass spectrometry', Journal of Chromatography, vol. 878, pp. 2363 - 2368, http://dx.doi.org/10.1016/j.jchromb.2010.07.017

Wallace H; Graham GG; Williams K; Day RO, 2010, 'A risk-benefit assessment of paracetamol (acetaminophen) combined with caffeine', Pain Medicine, vol. 11, pp. 951 - 965, http://dx.doi.org/10.1111/j.1526-4637.2010.00867.x

Day RO; Liauw WS; Tozer L; McElduff P; Beckett RJ; Williams K, 2010, 'A double-blind, placebo-controlled study of the short term effects of a spring water supplemented with magnesium bicarbonate on acid/base balance, bone metabolism and cardiovascular risk factors in postmenpausal women', BMC Research Notes, vol. 3, pp. 1 - 8, http://dx.doi.org/10.1186/1756-0500-3-180

Pett SL; Mccarthy M; Cooper DA; MacRae K; Tendolkar A; Norris R; Strizki J; Williams KM; Emery S, 2009, 'A Phase I study to explore the activity and safety of SCH532706, a small molecule chemokine receptor-5 antagonist in HIV type-1-infected patients', Antiviral Therapy, vol. 14, pp. 111 - 115

Indraratna P; Williams KM; Graham GG; Day RO, 2009, 'Hyperuricemia, Cardiovascular Disease and the Metabolic Syndrome', The Journal of Rheumatology, vol. 36, pp. 2842 - 2843, http://dx.doi.org/10.3899/jrheum.090500

Burrell C; Booy R; Wood N; Egan AM; Taverner D; Williams K; Liauw W; Moskwa A; Pepin-Covatta S; Saville M, 2008, 'Immunogenicity of a reduced dose of A/H3N2 in the 2005 southern hemisphere formulation of inactivated split influenza vaccine', Influenza and other Respiratory Viruses, vol. 2, pp. 93 - 98, http://dx.doi.org/10.1111/j.1750-2659.2008.00039.x

Lu CY; Macneill P; Williams K; Day R, 2008, 'Access to high cost medicines in Australia: Ethical perspectives', Australia and New Zealand Health Policy, vol. 5, http://dx.doi.org/10.1186/1743-8462-5-4

Abdul M; Jiang XM; Day RO; Roufogalis B; Liauw WS; Xu H; Mclachlan AJ, 2008, 'Pharmacodynamic interaction of warfarin with cranberry but not with garlic in healthy subjects', British Journal of Pharmacology, vol. 154, pp. 1691 - 1700, http://dx.doi.org/10.1038/bjp.2008.210

Xu H; Liauw WS; Murray M; Day RO; Mclachlan AJ, 2008, 'Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide', British Journal of Pharmacology, vol. 153, pp. 1579 - 1586, http://dx.doi.org/10.1038/sj.bjp.0707685

Lee M; Graham GG; Williams KM; Day RO, 2008, 'A benefit-risk assessment of benzbromarone in the treatment of gout - was its withdrawal from the market in the best interest of patients?', Drug Safety, vol. 31, pp. 643 - 665, http://dx.doi.org/10.2165/00002018-200831080-00002

Stocker S; Williams KM; Mclachlan AJ; Graham GG; Day RO, 2008, 'Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in healthy subjects', Clinical Pharmacokinetics, vol. 47, pp. 111 - 118, http://dx.doi.org/10.2165/00003088-200847020-00004

Lu CY; Williams KM; Day RO, 2008, 'Access to biologic medicines for the treatment of rheumatic diseases: lessons from Australia', International Journal of Rheumatology, vol. 11, pp. 11 - 14, http://dx.doi.org/10.1111/j.1756-185X.2008.00322.x

McLachlan AJ; Day RO; Williams KM; Graham GG, 2008, 'Maximising gout therapy', Australian Journal of Pharmacy, vol. 89, pp. 86 - 88

Lu CY; Williams KM; Day RO, 2007, 'The funding and use of high-cost medicines in Australia: The example of anti-rheumatic biological medicines', Australia and New Zealand Health Policy, vol. 4, http://dx.doi.org/10.1186/1743-8462-4-2

Day RO; Graham G; Williams K, 2007, 'Fenofibratewarfarin interaction [1]', Australian Prescriber, vol. 30, pp. 32, http://dx.doi.org/10.18773/austprescr.2007.014

Winston A; Mallon PW; Satchell C; MacRae K; Williams KM; Schutz M; Law MG; Cooper DA; Emery S, 2007, 'The safety, efficacy, and pharmacokinetic profile of a switch in antiretroviral therapy to saquinavir, ritonavir, and atazanavir alone for 48 weeks and a switch in the saquinavir formulation', Clinical Infectious Diseases, vol. 44, pp. 1475 - 1483, http://dx.doi.org/10.1086/517507

Day RO; Graham GG; Hicks M; Mclachlan AJ; Stocker S; Williams KM, 2007, 'Clinical pharmacokinetics and pharmacodynamics of allopurinol and oxypurinol', Clinical Pharmacokinetics, vol. 46, pp. 623 - 644, http://dx.doi.org/10.2165/00003088-200746080-00001

Lu C; Ritchie JE; Williams KM; Day RO, 2007, 'The views of stakeholders on controlled access schemes for high-cost antirheumatic biological medicines in Australia', Australia and New Zealand Health Policy, vol. 4, http://dx.doi.org/10.1186/1743-8462-4-26

Lu CY; Williams KM; Day RO, 2007, 'Has the use of disease-modifying anti-rheumatic drugs changed as a consequence of controlled access to high-cost biological agents through the Pharmaceutical Benefits Scheme?', Internal Medicine Journal, vol. 37, pp. 601 - 606, http://dx.doi.org/10.1111/j.1445-5994.2007.01396.x

Day RO; Williams KM, 2007, 'Open-label extension studies - Do they provide meaningful information on the safety of new drugs?', Drug Safety, vol. 30, pp. 93 - 105, http://dx.doi.org/10.2165/00002018-200730020-00001

Lu CY; Williams KM; Day RO, 2006, 'Accessing health outcome data on high-cost medicines in Australia', Medical Journal of Australia, vol. 184, pp. 411 - 413

Lu CY; Williams KM; Day RO, 2006, 'Access to tumour necrosis factor inhibitors for rheumatoid arthritis treatment under the Australian Pharmaceutical Benefits Scheme: are we on target?', Internal Medicine Journal, vol. 36, pp. 19 - 27, http://dx.doi.org/10.1111/j.1445-5994.2005.00992.x

Loboz K; Gross AS; Williams KM; Liauw WS; Day RO; Blievernicht J; Zanger U; McLachlan AJ, 2006, 'Cytochrome P450 2B6 activity as measured by bupropion hydroxylation: Effect of induction by rifampin and ethnicity', Clinical Pharmacology and Therapeutics, vol. 80, pp. 75 - 84, http://dx.doi.org/10.1016/j.clpt.2006.03.010

Lu CY; Williams KM; Day RO, 2006, 'Access to high-cost medicines for the treatment of rheumatoid arthritis under Australia's pharmaceutical benefits scheme', Pharmacoepidemiology and Drug Safety, vol. 15, pp. S213 - S213, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000240281200458&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Lu CY; Williams KM; Day RO, 2006, 'Utilisation of anti-rheumatic drugs in Australia: Impact of introducing high-cost biologics under the pharmaceutical benefits scheme', Pharmacoepidemiology and Drug Safety, vol. 15, pp. S213 - S213, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000240281200457&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Jiang X; Williams KM; Liauw WS; Ammit A; Roufogalis B; Duke C; Day RO; McLachlan AJ, 2005, 'Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects', British Journal of Clinical Pharmacology, vol. 59, pp. 425 - 432, http://dx.doi.org/10.1111/j.1365-2125.2005.02322.x

Mallon PW; Unemori P; Sedwell R; Morey AL; Rafferty M; Williams KM; Chisholm DJ; Samaras K; Emery S; Kelleher AD; Cooper DA; Carr AD, 2005, 'In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA', Journal of Infectious Diseases, vol. 191, pp. 1686 - 1696, http://dx.doi.org/10.1086/429697

Lu CY; Ritchie JE; Williams KM; Day RO, 2005, 'Recent developments in targeting access to high cost medicines in Australia', Australia and New Zealand Health Policy, vol. 2, pp. 1 - 8, http://dx.doi.org/10.1186/1743-8462-2-28

Jiang X; Williams KM; Liauw WS; Ammit AJ; Roufogalis BD; Duke CC; Day RO; McLachlan AJ, 2004, 'Erratum: Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects (British Journal of Clinical Pharmacology (2004) 57 (592-599))', British Journal of Clinical Pharmacology, vol. 58, pp. 102, http://dx.doi.org/10.1111/j.1365-2125.2004.02155.x

Williams KM, 2004, 'Stereoselective disposition of ibuprofen enantiomers in man - Author's commentary', British Journal of Clinical Pharmacology, vol. 58, pp. S765 - S766

Liauw WS; Williams KM; Day RO, 2004, 'Protocol Appraisal: A Study Site's Viewpoint', Applied Clinical Trials, vol. 13, pp. 34 - 42

Pett SL; Williams LA; Day RO; Lloyd AR; Carr AD; Clezy KR; Emery S; Kaplan E; Mcphee D; Mclachlan AJ; Gelder F; Lewin S; Liauw WS; Williams KM, 2004, 'A phase I study of the pharmacokinetics and safety of passive immunotherapy with caprine anti-HIV antibodies, (PE)HRG214, in HIV-1-infected individuals', HIV Clinical Trials, vol. 5, pp. 91 - 98, http://dx.doi.org/10.1310/1FLN-8KFC-5HEQ-K19J

Lu CY; Williams KM; March LM; Bertouch JV; Day RO, 2004, 'Subsided access to TNF alpha inhibitors: is the rationale for exclusion of rheumatoid-factor-negative patients defensible?', Medical Journal of Australia, vol. 181, pp. 457 - 457

Jiang XM; Williams KM; Liauw WS; Ammit A; Roufogalis B; Duke C; Day RO; Mclachlan AJ, 2004, 'Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects', British Journal of Clinical Pharmacology, vol. 57, pp. 592 - 599, http://dx.doi.org/10.1111/j.1365-2125.2003.02051.x

Lomas M; Liauw WS; Packham D; Williams KM; Kelleher AD; Zaunders J; Ward RL, 2004, 'Phase I clinical trial of a human idiotypic p53 vaccine in patients with advanced malignancy', Annals of Oncology, vol. 15, pp. 324 - 329, http://dx.doi.org/10.1093/annonc/mdh053

Lu CY; Williams KM; Day RO; March LM; Sansom L; Bertouch JV, 2004, 'Access to high cost drugs in Australia', British Medical Journal: Clinical Research, vol. 329, pp. 415 - 416

Jiang XM; Williams KM; Liauw WS; Ammit A; Roufogalis B; Duke C; Day RO; Mclachlan AJ, 2004, 'Pharmacokinetic-pharmacodynamic modelling to investigate herb-drug interactions with warfarin', Clinical and Experimental Pharmacology and Physiology, vol. 31, pp. A227 - A227, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000225490400052&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Mallon PW; Unemori P; Sedwell R; Morey AL; Rafferty M; Williams KM; Chisholm DJ; Samaras K; Emery S; Kelleher AD; Cooper DA; Carr AD, 2004, 'In vivo nucleoside reverse transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes independent to HIV infection', Antiviral Therapy, vol. 9, pp. L11 - L11, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000231616000044&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Mallon PW; Sedwell R; Unemori P; Rafferty M; Williams KM; Chisholm DJ; Samaras K; Emery S; Kelleher AD; Cooper DA; Carr AD, 2004, 'Changes in nuclear gene expression resulting from NRTI-induced inhibition of mitochondrial transcription reveal links between mitochondrial dysfunction and lipid metabolism', Antiviral Therapy, vol. 9, pp. L56 - L56, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000231616000125&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Mallon PW; Sedwell R; Unemori P; Merlin K; McGinley C; Ammaranond P; Peperias M; Rafferty M; Williams KM; Samaras K; Morey AL; Chisholm DJ; Kelleher AD; Cooper DA; Carr AD, 2004, 'Nucleoside reverse transcriptase inhibitors (NRTI) decrease adipocyte and monocyte mitochondrial (mt) messenger RNA transcription in the absence of changes in mtDNA or cell morphology', Antiviral Therapy, vol. 9, pp. L56 - L57, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000231616000126&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Lee EJ; Williams KM; Day RO; Graham GG; Champion D, 2004, 'Stereoselective disposition of ibuprofen enantiomers in man (Reprintedfrom Br J Clin Pharmacol, vol 19, pg 669-674, 1985)', British Journal of Clinical Pharmacology, vol. 58, pp. S759 - S764, http://dx.doi.org/10.1111/j.1365-2125.2004.02288.x

Wren BG; Day RO; Mclachlan AJ; Williams KM, 2003, 'Pharmacokinetics of estradiol, progesterone, testosterone and dehydroepiandrosterone after transbuccal administration to postmenopausal women', Climacteric, vol. 6, pp. 104 - 111, http://dx.doi.org/10.1080/cmt.6.2.104.111

Sasongko L; Williams KM; Day RO; Mclachlan AJ, 2003, 'Human subcutaneous tissue distribution of fluconazole: comparison of microdialysis and suction blister techniques', British Journal of Pharmacology, vol. 56, pp. 551 - 561, http://dx.doi.org/10.1046/j.1365-2125.2003.01930.x

Sasongko L; Ramzan I; Williams KM; McLachlan AJ, 2002, 'Muscle distribution of the neuromuscular blocker gallamine using microdialysis', Journal of Pharmaceutical Sciences, vol. 91, pp. 769 - 775, http://dx.doi.org/10.1002/jps.10082

Williams KM; Cooper S; Parisis K; Handel M; Day RO, 2001, 'The skin suction blister: A human model of inflammation', Clinical Pharmacology and Therapeutics, vol. 69

Sasongko L; Ramzan I; Williams KM; Mclachlan AJ, 2001, 'Application of a high-performance liquid chromatographic assay for the neuromuscular blocker gallamine to analysis of rat plasma, muscle and microdialysate samples', Journal of Chromatography B, vol. 754, pp. 467 - 475, http://dx.doi.org/10.1016/S0378-4347(01)00032-9

Davies NP; Mclachlan AJ; Day RO; Williams KM, 2000, 'Clinical pharmacokinetics and pharmacodynamics of celecoxib: A selective cyclo-oxygenase-2 inhibitor.', Clinical Pharmacokinetics, vol. 38, pp. 225 - 242, http://dx.doi.org/10.2165/00003088-200038030-00003

Sasongko L; Williams KL; Ramzan I; Mclachlan AJ, 2000, 'Assessment of in vitro in vivo recovery of gallamine using microdialysis', Journal of Pharmacological and Toxicological Methods, vol. 44, pp. 519 - 525, http://dx.doi.org/10.1016/S1056-8719(00)00117-9

Williams KM; Day RO; Roberts LK; Harbin JA, 1999, 'A comparison of the efficacy of α-ketobutyric acid (KBA), nordihidro-guaiaretic acid (NDGA), salicylic acid (SA), and placebo (P) in the accelerated removal of corns', Clinical Pharmacology and Therapeutics, vol. 65, pp. 122, http://dx.doi.org/10.1016/S0009-9236(99)80022-8

Day RO; Mclachlan AJ; Graham GG; Williams KM, 1999, 'Pharmacokinetics of non-steroidal anti-inflammatory drugs in synovial fluid', Clinical Pharmacokinetics, vol. 36, pp. 191 - 210, http://dx.doi.org/10.2165/00003088-199936030-00002

Erb K; Brugger R; Williams KM; Geisslinger G, 1999, 'Stereoselective disposition of tiaprofenic acid enantiomers in rats', Chirality, vol. 11, pp. 103 - 108

Browne GS; Nelson CJ; Nguyen TM; Ellis B; Day RO; Williams KM, 1999, 'Stereoselective and substrate-dependent inhibition of hepatic mitochondrial B-oxidation and oxidative phosphorylation by the non-steroidal anti-inflammatory drugs ibuprofen, flurbiprofen and ketorolac', Biochemical Pharmacology, vol. 57, pp. 837 - 844, http://dx.doi.org/10.1016/S0006-2952(98)00342-6

Erb K; Brugger R; Williams K; Geisslinger G, 1999, 'Stereoselective disposition of tiaprofenic acid enantiomers in rats.', Chirality, vol. 11, pp. 103 - 108, http://dx.doi.org/10.1002/(SICI)1520-636X(1999)11:2<103::AID-CHIR4>3.0.CO;2-1

Campbell TJ; Williams KM, 1998, 'Therapeutic drug monitoring: Antiarrhythmic drugs', British Journal of Clinical Pharmacology, vol. 46, pp. 307 - 319, http://dx.doi.org/10.1046/j.1365-2125.1998.t01-1-00768.x

Day RO; Williams KM; Campbell TJ, 1998, 'The death of a normal healthy volunteer in a human research project: implications for Australian clinical research', Medical Journal of Australia, vol. 168, pp. 449 - 451

Scheuerer S; Williams KM; Brugger R; Mclachlan AJ; Brune K; Day RO; Geisslinger G, 1998, 'Effect of clofibrate on the chiral inversion of ibuprofen in rats', Journal of Pharmacology and Experimental Therapeutics, vol. 284, pp. 1132 - 1138

Campbell TJ; Williams KM, 1998, 'Therapeutic Drug monitoring of antiarrhythmic drugs', British Journal of Clinical Pharmacology, vol. 52, pp. 307 - 319

Scheuerer S; Hall ST; Williams KM; Geisslinger G, 1998, 'Effect of clofibrate on the chiral inversion of ibuprofen in healthy volunteers', Clinical Pharmacology and Therapeutics, vol. 64, pp. 168 - 176, http://dx.doi.org/10.1016/S0009-9236(98)90150-3

Williams KM; Turner J; Geisslinger G; Day RO, 1997, 'The suction blister as an in vivo model of inflammation: Interblister variability and preliminary studies of the disposition of methotrexate', Clinical Pharmacology and Therapeutics, vol. 61, pp. 160

Williams KM; Turner J; Geisslinger G; Day RO, 1997, 'The suction blister as an in vivo model of inflammation: Interblister variability and preliminary studies of the disposition of methotrexate', CLINICAL PHARMACOLOGY & THERAPEUTICS, vol. 61, pp. PI93 - PI93, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997WJ68400093&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Wang X; Liu Y; Nair UB; Armstrong DW; Ellis B; Williams KM, 1997, 'Enantiomeric composition of monoterpenes in conifer resins', Tetrahedron - Asymmetry, pp. 3977 - 3984

Oelkers R; Neupert W; Williams KM; Brune K; Geisslinger G, 1997, 'Disposition and effects of Flurbiprofen enantiomers in human serum and blister fluid', British Journal of Clinical Pharmacology, vol. 43, pp. 145 - 153

Donnelly R; Williams KM; Baker A; Badcock CA; Day RO; Seale JP, 1997, 'Effects of budesonide and fluticasoue on 24-hour plasma cortisol: A dose-response study.', American Journal of Respiratory and Critical Care Medicine, vol. 156, pp. 1746 - 1751, http://dx.doi.org/10.1164/ajrccm.156.6.9703003

Day RO; Williams KM; Geisslinger G, 1996, 'Naproxen concentrations in plasma and synovial fluid and effects on prostanoid concentrations - Reply', JOURNAL OF RHEUMATOLOGY, vol. 23, pp. 1827 - 1828, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996VL78300035&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Simkin PA; Bassett JE; Lapicque F; Bertin P; Netter P; Day RO; Williams KM; Geisslinger G, 1996, 'Naproxen concentration in plasma and synovial fluid and effects on prostanoid concentrations [1]', Journal of Rheumatology, vol. 23, pp. 1826 - 1828

Soong R; Knowles S; Williams KM; Hammond IG; Wysocki SJ; Iacopetta BJ, 1996, 'Overexpression of p53 protein is an independent prognostic indicator in human endometrial carcinoma', British Journal of Cancer, pp. 562 - 567

Zachara NE; Packer H; Temple MD; Slade M; Jardine RJ; Karuso P; Moss CJ; Mabbutt BC; Curmi PM; Williams KM; Gooley AA, 1996, 'Recombinant prespore-specific antigen from Dictyostelium discoideum is a B-sheet glycoprotein with a spacer peptide modified by O-linked N-acetyglucosamine', European Journal of Biochemistry, vol. 238, pp. 511 - 518, http://dx.doi.org/10.1111/j.1432-1033.1996.0511z.x

Geisslinger G; Oeikers R; Neupert W; Williams KM; Brune K, 1996, 'Effect of Flurbiprofen (FLU) Enantiomers on Prostaglandin E2 (PGE2) and Substance p (SP) Levels in Human Suction Blister', Clinical Pharmacology & Therapeutics, vol. 59, pp. 208 - 208, http://dx.doi.org/10.1038/sj.clpt.1996.332

Day RO; Francis H; Vial J; Geisslinger G; Williams KM, 1995, 'Naproxen concentrations in plasma and synovial fluid and effects on prostanoid concentrations', Journal of Rheumatology, vol. 22, pp. 2295 - 2303

Day RO; Francis H; Vial JH; Geisslinger G; Williams KM, 1995, 'Pharmacokinetics and pharmacodynamics of naproxen in synovial fluid and plasma', Journal of Rheumatology, pp. 2295 - 2303

Walsh BR; Gooley AA; Williams KM; Breit SN, 1995, 'Identification of macrophage activation associated proteins by two-dimensional gel electrophoresis and microsequencing', Journal of Leukocyte Biology, vol. 57, pp. 507 - 512, http://dx.doi.org/10.1002/jlb.57.3.507

Wasinger VC; Cordwell SJ; Poljak A; Yan JX; Gooley AA; Wilkins MR; Duncan MW; Harris RI; Williams KM; Humphery-Smith I, 1995, 'Progress with gene-product mapping of the mollicutes: mycroplasma genitalium', Electrophoresis, vol. 16, pp. 1090 - 1094, http://dx.doi.org/10.1002/elps.11501601185

Cordwell SJ; Wilkins MR; Poljak A; Gooley AA; Duncan MW; Williams KM; Humphery-Smith I, 1995, 'Cross-species identification of proteins separated by two-dimensional gel electrophoresis using MALDI-TOF mass spectrometry and amino acid composition', Electrophoresis, vol. 16, pp. 438 - 443, http://dx.doi.org/10.1002/elps.1150160171

Day RO; Geisslinger G; Paull P; Williams KM, 1995, 'The effect of tenoxicam on tolbutamide pharmacokinetics and glucose concentrations in healthy volunteers', International journal of clinical pharmacology, vol. 33, pp. 308 - 310

Mclachlan AJ; Williams KM, 1995, 'Estimation of the rate and extent of chiral inversion using linear systems analysis', Chirality, vol. 7, pp. 632 - 635, http://dx.doi.org/10.1002/chir.530070814

Day R; Geisslinger G; Paull P; Williams K, 1994, 'Neither cimetidine nor probenecid affect the pharmacokinetics of tenoxicam in normal volunteers.', British Journal of Clinical Pharmacology, vol. 37, pp. 79 - 81, http://dx.doi.org/10.1111/j.1365-2125.1994.tb04244.x

Seideman P; Lohrer F; Graham G; Duncan M; Williams K; Day R, 1994, 'The stereoselective disposition of the enantiomers of ibuprofen in blood, blister and synovial fluid.', British Journal of Clinical Pharmacology, vol. 38, pp. 221 - 227, http://dx.doi.org/10.1111/j.1365-2125.1994.tb04345.x

Schmidt N; Brune K; Williams KM; Geisslinger G, 1994, 'Stereoselective pharmacokinetics of methadone in beagle dogs.', Chirality, vol. 6, pp. 492 - 495, http://dx.doi.org/10.1002/chir.530060608

Sauernheimer C; Williams KM; Brune K; Geisslinger G, 1994, 'Application of microdialysis to the pharmacokinetics of analgesics: problems with reduction of dialysis efficiency in vivo.', J Pharmacol Toxicol Methods, vol. 32, pp. 149 - 154, http://dx.doi.org/10.1016/1056-8719(94)90068-x

DAY RO; NGUYEN T; WILLIAMS KM, 1993, 'TENOXICAM DOSE CONCENTRATION RESPONSE RELATIONSHIP IN RHEUMATOID-ARTHRITIS (RA)', CLINICAL PHARMACOLOGY & THERAPEUTICS, vol. 53, pp. 152 - 152, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993KP26900067&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Day RO; Brooks PM; Williams KM; Graham GG, 1993, 'Meeting report: Third world conference on variability in response to anti-rheumatic drugs, Singapore, July 22-24, 1992', Agents and Actions, vol. 38

Williams KM; Day RO; Breit SN, 1993, 'Biochemical actions and clinical pharmacology of anti-inflammatory drugs', Advances in Drug Research, vol. 24, pp. 121 - 198

Day RO; Brooks PM; Williams KM; Graham GG, 1993, 'Third World conference on variability in response to anti-rheumatic drugs, Singapore, July 22-24, 1992.', Agents and actions, vol. 38, http://dx.doi.org/10.1007/bf01976204

Williams KM, 1993, 'Chiral NSAIDs: So what?', Agents and Actions, vol. 44, pp. 15 - 22

Brooks PM; Day RO; Graham GG; Williams KM, 1993, 'Preface', Agents and Actions, vol. 44

Zhao B; Geisslinger G; Hall I; Day RO; Williams KM, 1992, 'The effect of the enantiomers of ibuprofen and flurbiprofen on the β‐oxidation of palmitate in the rat', Chirality, vol. 4, pp. 137 - 141, http://dx.doi.org/10.1002/chir.530040302

Williams KM; Knihinicki RD; Day RO, 1991, 'Pharmacokinetics of the enantiomers of ibuprofen in the rabbit', Agents and Actions, vol. 34, pp. 381 - 386, http://dx.doi.org/10.1007/BF01988732

Knihinicki RD; Day RO; Williams KM, 1991, 'Chiral inversion of 2-arylpropionic acid non-steroidal anti-inflammatory drugs-II Racemization and hydrolysis of (R)- and (S)-ibuprofen-CoA thioesters', Biochemical Pharmacology, vol. 42, pp. 1905 - 1911, http://dx.doi.org/10.1016/0006-2952(91)90588-V

Day RO; Williams KM; Graham S; Handel M, 1991, 'The pharmacokinetics of total and unbound concentrations of tenoxicam in synovial fluid and plasma', Arthritis & Rheumatism, vol. 34, pp. 751 - 760, http://dx.doi.org/10.1002/art.1780340617

Williams KM, 1991, 'Molecular Asymmetry and Its Pharmacological Consequences', Advances in Pharmacology, vol. 22, pp. 57 - 135, http://dx.doi.org/10.1016/S1054-3589(08)60033-2

Nuernberg B; Knihinicki R; Williams K; Freeman GE; Dalton C; Brooks PM; Day RO, 1990, 'Anti-inflammatory effects and disposition of S- and R-flurbiprofen in the rat', European Journal of Pharmacology, vol. 183, pp. 1591 - 1592, http://dx.doi.org/10.1016/0014-2999(90)94757-O

Knihinicki RD; Day RO; Graham GG; Williams KM, 1990, 'Stereoselective disposition of ibuprofen and flurbiprofen in rats', Chirality, vol. 2, pp. 134 - 140, http://dx.doi.org/10.1002/chir.530020303

Williams KM, 1990, 'Enantiomers in arthritic disorders', Pharmacology and Therapeutics, vol. 46, pp. 273 - 295, http://dx.doi.org/10.1016/0163-7258(90)90095-J

Lee EJD; Willia KM, 1990, 'Chirality Clinical Pharmacokinetic and Pharmacodynamic Considerations', Clinical Pharmacokinetics, vol. 18, pp. 339 - 345, http://dx.doi.org/10.2165/00003088-199018050-00001

Knihinicki RD; Williams KM; Day RO, 1989, 'Chiral inversion of 2-arylpropionic acid non-steroidal anti-inflammatory drugs-1. In vitro studies of ibuprofen and flurbiprofen', Biochemical Pharmacology, vol. 38, pp. 4389 - 4395, http://dx.doi.org/10.1016/0006-2952(89)90647-3

Williams KM, 1989, 'CHIRALITY: PHARMACOKINETICS AND PHARMACODYNAMICS IN 3 DIMENSIONS', Clinical and Experimental Pharmacology and Physiology, vol. 16, pp. 465 - 470, http://dx.doi.org/10.1111/j.1440-1681.1989.tb01589.x

Day RO; Graham GG; Williams KM, 1988, 'Pharmacokinetics of non-steroidal anti-inflammatory drugs', Bailliere's Clinical Rheumatology, vol. 2, pp. 363 - 393, http://dx.doi.org/10.1016/S0950-3579(88)80019-0

Day RO; Graham GG; Willia KM; Brooks PM, 1988, 'Variability in Response to NSAIDs: Fact or Fiction?', Drugs, vol. 36, pp. 643 - 651, http://dx.doi.org/10.2165/00003495-198836060-00001

Day RO; Williams KM; Graham GG; Lee EJ; Knihinicki RD; Champion GD, 1988, 'Stereoselective disposition of ibuprofen enantiomers in synovial fluid', Clinical Pharmacology and Therapeutics, vol. 43, pp. 480 - 487, http://dx.doi.org/10.1038/clpt.1988.62

Day R; Paull P; Lam S; Swanson B; Williams K; Wade D, 1988, 'The effect of concurrent aspirin upon plasma concentrations of tenoxicam.', British Journal of Clinical Pharmacology, vol. 26, pp. 455 - 462, http://dx.doi.org/10.1111/j.1365-2125.1988.tb03405.x

Williams KM; Day RO, 1988, 'The contribution of enantiomers to variability in response to anti-inflammatory drugs.', Agents and actions. Supplements, vol. 24, pp. 76 - 84, http://dx.doi.org/10.1007/978-3-0348-9160-8_7

Day RO; Graham GG; Williams KM; David Champion G; de Jager J, 1987, 'Clinical pharmacology of non-steroidal anti-inflammatory drugs', Pharmacology and Therapeutics, vol. 33, pp. 383 - 433, http://dx.doi.org/10.1016/0163-7258(87)90072-6

Williams K; Day R; Knihinicki R; Duffield A, 1986, 'The stereoselective uptake of ibuprofen enantiomers into adipose tissue', Biochemical Pharmacology, vol. 35, pp. 3403 - 3405, http://dx.doi.org/10.1016/0006-2952(86)90443-0

WILLIAMS KM; DAY RO; KNIHINICKI RD; DUFFIELD AM, 1986, 'STEREOSELECTIVE INCORPORATION OF IBUPROFEN ENANTIOMERS INTO ADIPOSE-TISSUE IN RATS AND MAN', ACTA PHARMACOLOGICA ET TOXICOLOGICA, vol. 59, pp. 192 - 192, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1986D896000552&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

DAY RO; WILLIAMS KM; LEE EJ; KNIHINICKI R, 1985, 'DISPOSITION OF ENANTIOMERS OF IBUPROFEN IN PLASMA AND SYNOVIAL-FLUID IN ARTHRITIC DISEASE', CLINICAL AND INVESTIGATIVE MEDICINE-MEDECINE CLINIQUE ET EXPERIMENTALE, vol. 8, pp. A58 - A58, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1985AQS8500134&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lee E; Williams K; Day R; Graham G; Champion D, 1985, 'Stereoselective disposition of ibuprofen enantiomers in man.', British Journal of Clinical Pharmacology, vol. 19, pp. 669 - 674, http://dx.doi.org/10.1111/j.1365-2125.1985.tb02694.x

Williams KM; Day RO, 1985, 'Stereoselective disposition--basis for variability in response to NSAID's.', Agents and actions. Supplements, vol. 17, pp. 119 - 126, http://dx.doi.org/10.1007/978-3-0348-7720-6_14

Williams K; Lee E, 1985, 'Importance of drug enantiomers in clinical pharmacology.', Drugs, vol. 30, pp. 333 - 354, http://dx.doi.org/10.2165/00003495-198530040-00003

Lee EJD; Williams KM; Graham GG; Day RO; Champion GD, 1984, 'Liquid chromatographic determination and plasma concentration profile of optical isomers of ibuprofen in humans', Journal of Pharmaceutical Sciences, vol. 73, pp. 1542 - 1544, http://dx.doi.org/10.1002/jps.2600731112

Williams KM, 1984, 'Kinetics of misonidazole enantiomers', Clinical Pharmacology and Therapeutics, vol. 36, pp. 817 - 823, http://dx.doi.org/10.1038/clpt.1984.262

Williams K; Begg E; Wade D; O'Shea K, 1983, 'No significant effect of metoclopramide on misonidazole elimination in man.', British Journal of Clinical Pharmacology, vol. 15, pp. 390 - 392, http://dx.doi.org/10.1111/j.1365-2125.1983.tb01519.x

Williams K; Begg E; Wade D; O'Shea K, 1983, 'Effects of phenytoin, phenobarbital, and ascorbic acid on misonidazole elimination', Clinical Pharmacology and Therapeutics, vol. 33, pp. 314 - 321, http://dx.doi.org/10.1038/clpt.1983.39

WILLIAMS KM; BEGG EJ; WADE DN; OSHEA K, 1983, 'THE EFFECT OF CIMETIDINE AND METOCLOPRAMIDE ON THE ELIMINATION OF MISONIDAZOLE (RO-07-0582) IN MAN', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol. 10, pp. 718 - 719, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1983RW31100131&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

BEGG EJ; WILLIAMS KM; WADE DN; OSHEA KF, 1983, 'NO SIGNIFICANT EFFECT OF CIMETIDINE ON THE PHARMACOKINETICS OF MISONIDAZOLE IN MAN', BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, vol. 15, pp. 575 - 576, http://dx.doi.org/10.1111/j.1365-2125.1983.tb02096.x

Begg E; Williams K; Wade D; O'Shea K, 1983, 'No significant effect of cimetidine on the pharmacokinetics of misonidazole in man.', British Journal of Clinical Pharmacology, vol. 15, pp. 575 - 576, http://dx.doi.org/10.1111/j.1365-2125.1983.tb02096.x

Williams KM; Begg EJ; Wade DN; O'Shea K, 1982, 'The effect of phenytoin, phenobarbitone and ascorbic acid on the elimination of misonidazole (Ro 07-0582) in man', Clinical and Experimental Pharmacology and Physiology, vol. 9, pp. 423

CHINWAY PM; WILLIAMS KM; WADE DN, 1982, 'A STUDY OF THE DISTRIBUTION AND ELIMINATION OF HIGH-DOSES OF DPH IN RABBITS', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol. 9, pp. 459 - 460, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1982PJ26400121&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tung C; Graham GG; Wade DN; Williams KM, 1982, 'The pharmacokinetics of chlorbutol in man', Biopharmaceutics & Drug Disposition, vol. 3, pp. 371 - 378, http://dx.doi.org/10.1002/bdd.2510030410

Williams KM; Duffield AM; Christopher RK; Finlayson PJ, 1981, 'Identification of minor metabolites of 5‐fluorocytosine in man by chemical ionization gas chromatography mass spectrometry', Biological Mass Spectrometry, vol. 8, pp. 179 - 182, http://dx.doi.org/10.1002/bms.1200080410

Tung C; Graham GG; Wade DN; Williams KM, 1980, 'The pharmacokinetics of chlorbutol', Clinical and Experimental Pharmacology and Physiology, vol. 7, pp. 672, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1980KV12600062&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

WILLIAMS KM; DUFFIELD AM; CHRISTOPHER RK; FINLAYSON PJ, 1980, 'MINOR METABOLITES OF 5-FLUOROCYTOSINE IN MAN', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol. 7, pp. 681 - 681, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1980KV12600077&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Chinwah P; Williams K, 1980, 'Comparison of enzyme immunoassay for gentamicin compared with other methods.', J Antimicrob Chemother, vol. 6, pp. 561 - 562, http://dx.doi.org/10.1093/jac/6.4.561

Williams KM; Chinwah PM; Cobcroft R, 1979, 'Crystalluria during flucytosine therapy.', Med J Aust, vol. 2, pp. 617, http://dx.doi.org/10.5694/j.1326-5377.1979.tb127231.x

Borody T; Chinwah PM; Graham GG; Wade DN; Williams KM, 1979, 'Chlorbutol toxicity and dependence', Medical Journal of Australia, vol. 1, pp. 288, http://dx.doi.org/10.5694/j.1326-5377.1979.tb112109.x

Ziegler JB; Graham GG; Day RO; Williams KM; Milligan MK, 1997, 'THERAPEUTIC CONSIDERATIONS FROM PHARMACOKINETICS AND METABOLISM: IBUPROFEN AND PARACETAMOL.', in Safety and Efficacy of non-prescription (OTC) analgesics and NSAIDs, Kluwer Academic Publishers, Dordrecht, presented at Safety and Efficacy of non-prescription analgesics and NSAIDS, San Francisco, California USA, 17 March 1997 -