Dr Yann Gambin
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Publications related to this Person
Book Chapters
O’Carroll A; Moustaqil M; Leitao ADG; Gambin Y; Sierecki E, 2016, 'Protein self-interaction in health and disease: How dimerization, oligomerization and polymerization modulate protein function', in Protein-Protein Interactions (PPIs): Types, Methods for Detection and Analysis, pp. 97 - 151
Journal articles
Pang SS; Bayly-Jones C; Radjainia M; Spicer BA; Law RHP; Hodel AW; Parsons ES; Ekkel SM; Conroy PJ; Ramm G, 2019, 'The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1', Nature communications, vol. 10, pp. 4288, http://dx.doi.org/10.1038/s41467-019-12279-2
McMahon KA; Wu Y; Gambin Y; Sierecki E; Tillu VA; Hall T; Martel N; Okano S; Moradi SV; Ruelcke JE, 2019, 'Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis', Nature Communications, vol. 10, http://dx.doi.org/10.1038/s41467-019-11111-1
Overman J; Fontaine F; Sears JW; Moustaqil M; Huang L; Meurer M; Chiang IK; Lesieur E; Patel J; Zuegg J, 2019, 'R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma', eLife, vol. 8, http://dx.doi.org/10.7554/eLife.43026
Monserrat-Martinez A; Gambin Y; Sierecki E, 2019, 'Thinking outside the bug: Molecular targets and strategies to overcome antibiotic resistance', International Journal of Molecular Sciences, vol. 20, http://dx.doi.org/10.3390/ijms20061255
Pham CLL; Shanmugam N; Strange M; O'Carroll A; Brown JWP; Sierecki E; Gambin Y; Steain M; Sunde M, 2019, 'Viral M45 and necroptosis-associated proteins form heteromeric amyloid assemblies', EMBO Reports, vol. 20, http://dx.doi.org/10.15252/embr.201846518
Moustaqil M; Fontaine F; Overman J; McCann A; Bailey TL; Soto PR; Bhumkar A; Giles N; Hunter DJB; Gambin Y, 2018, 'Homodimerization regulates an endothelial specific signature of the SOX18 transcription factor', Nucleic Acids Research, vol. 46, pp. 11381 - 11395, http://dx.doi.org/10.1093/nar/gky897
O'Carroll A; Chauvin B; Brown JWP; Meagher A; Coyle J; Schill J; Bhumkhar A; Hunter DJB; Ve T; Kobe B, 2018, 'Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88', BMC Biology, vol. 16, http://dx.doi.org/10.1186/s12915-018-0611-7
Steinbeck J; Ross IL; Rothnagel R; Gäbelein P; Schulze S; Giles N; Ali R; Drysdale R; Sierecki E; Gambin Y, 2018, 'Structure of a PSI-LHCI-cyt b
Hussein WM; Choi PM; Zhang C; Sierecki E; Johnston W; Jia Z; Monteiro MJ; Skwarczynski M; Gambin Y; Toth I, 2018, 'Investigating the affinity of poly tert-butyl acrylate toward Toll-Like Receptor 2', AIMS ALLERGY AND IMMUNOLOGY, vol. 2, pp. 141 - 147, http://dx.doi.org/10.3934/Allergy.2018.3.141
Jung WR; Sierecki E; Bastiani M; O'Carroll A; Alexandrov K; Rae J; Johnston W; Hunter DJB; Ferguson C; Gambin Y, 2018, 'Cell-free formation and interactome analysis of caveolae', Journal of Cell Biology, vol. 217, pp. 2141 - 2165, http://dx.doi.org/10.1083/jcb.201707004
Ariotti N; Rae J; Giles N; Martel N; Sierecki E; Gambin Y; Hall TE; Parton RG, 2018, 'Ultrastructural localisation of protein interactions using conditionally stable nanobodies', PLoS Biology, vol. 16, http://dx.doi.org/10.1371/journal.pbio.2005473
Hunter DJB; Bhumkar A; Giles N; Sierecki E; Gambin Y, 2018, 'Unexpected instabilities explain batch-to-batch variability in cell-free protein expression systems', Biotechnology and Bioengineering, vol. 115, pp. 1904 - 1914, http://dx.doi.org/10.1002/bit.26604
Fontaine FR; Goodall S; Prokop JW; Howard CB; Moustaqil M; Kumble S; Rasicci DT; Osborne GW; Gambin Y; Sierecki E, 2018, 'Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach', mAbs, vol. 10, pp. 596 - 606, http://dx.doi.org/10.1080/19420862.2018.1451288
Gambin Y; Giles N; O'Carroll A; Polinkovsky ME; Hunter DJB; Sierecki E, 2018, 'Corrigendum to “Single-Molecule Fluorescence Reveals the Oligomerisation and Folding Steps Driving the Prion-like Behaviour of ASC” [J. Mol. Biol. 430 (4) (February 16, 2018) 491–508] (S00222836173059', Journal of Molecular Biology, vol. 430, pp. 1263, http://dx.doi.org/10.1016/j.jmb.2018.02.011
Healey RD; Wojciechowski JP; Monserrat-Martinez A; Tan SL; Marquis CP; Sierecki E; Gambin Y; Finch AM; Thordarson P, 2018, 'Design, Synthesis, and Evaluation of N- and C-Terminal Protein Bioconjugates as G Protein-Coupled Receptor Agonists', Bioconjugate Chemistry, vol. 29, pp. 403 - 409, http://dx.doi.org/10.1021/acs.bioconjchem.7b00716
Gambin Y; Giles N; O'Carroll A; Polinkovsky M; Hunter D; Sierecki E, 2018, 'Single-Molecule Fluorescence Reveals the Oligomerization and Folding Steps Driving the Prion-like Behavior of ASC', Journal of Molecular Biology, vol. 430, pp. 491 - 508, http://dx.doi.org/10.1016/j.jmb.2017.12.013
Leitao A; Bhumkar A; Hunter DJB; Gambin Y; Sierecki E, 2018, 'Unveiling a selective mechanism for the inhibition of α-synuclein aggregation by β-synuclein', International Journal of Molecular Sciences, vol. 19, http://dx.doi.org/10.3390/ijms19020334
Moustaqil M; Bhumkar A; Gonzalez L; Raoul L; Hunter DJB; Carrive P; Sierecki E; Gambin Y, 2017, 'A split-luciferase reporter recognizing GFP and mCherry tags to facilitate studies of protein–protein interactions', International Journal of Molecular Sciences, vol. 18, http://dx.doi.org/10.3390/ijms18122681
Ve T; Vajjhala PR; Hedger A; Croll T; Dimaio F; Horsefield S; Yu X; Lavrencic P; Hassan Z; Morgan GP, 2017, 'Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling', Nature Structural and Molecular Biology, vol. 24, pp. 743 - 751, http://dx.doi.org/10.1038/nsmb.3444
Fontaine F; Overman J; Moustaqil M; Mamidyala S; Salim A; Narasimhan K; Prokoph N; Robertson AAB; Lua L; Alexandrov K, 2017, 'Small-Molecule Inhibitors of the SOX18 Transcription Factor', Cell Chemical Biology, vol. 24, pp. 346 - 359, http://dx.doi.org/10.1016/j.chembiol.2017.01.003
Overman J; Fontaine F; Moustaqil M; Mittal D; Sierecki E; Sacilotto N; Zuegg J; Robertson AAB; Holmes K; Salim AA, 2017, 'Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice', eLife, vol. 6, http://dx.doi.org/10.7554/eLife.21221
Gambin Y; Polinkovsky M; Francois B; Giles N; Bhumkar A; Sierecki E, 2016, 'Confocal Spectroscopy to Study Dimerization, Oligomerization and Aggregation of Proteins: A Practical Guide', International journal of molecular sciences, vol. 17, http://dx.doi.org/10.3390/ijms17050655
Hussein WM; Choi PM; Zhang C; Su M; Sierecki E; Johnston W; Fagan V; Alexandrov K; Skwarczynski M; Gambin Y, 2016, 'Evaluation of lipopeptides as toll-like receptor 2 ligands', Current Drug Delivery, vol. 13, http://dx.doi.org/10.2174/1567201813666160804114107
Sierecki E; Giles N; Bowden Q; Polinkovsky ME; Steinbeck J; Arrioti N; Rahman D; Bhumkar A; Nicovich PR; Ross I, 2016, 'Nanomolar oligomerization and selective co-aggregation of α-synuclein pathogenic mutants revealed by single-molecule fluorescence', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep37630
Chai YJ; Sierecki E; Tomatis VM; Gormal RS; Giles N; Morrow IC; Xia D; Götz J; Parton RG; Collins BM, 2016, 'Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation', Journal of Cell Biology, vol. 214, http://dx.doi.org/10.1083/jcb.201512016
Gagoski D; Polinkovsky ME; Mureev S; Kunert A; Johnston W; Gambin Y; Alexandrov K, 2016, 'Performance benchmarking of four cell-free protein expression systems', Biotechnology and Bioengineering, vol. 113, pp. 292 - 300, http://dx.doi.org/10.1002/bit.25814
Gagoski D; Polinkovsky ME; Mureev S; Kunert A; Johnston W; Gambin Y; Alexandrov K, 2015, 'Performance benchmarking of four cell-free protein expression systems', Biotechnology and Bioengineering, http://dx.doi.org/10.1002/bit.25814
Gambin Y; Ariotti N; McMahon KA; Bastiani M; Sierecki E; Kovtun O; Polinkovsky ME; Magenau A; Jung W; Okano S, 2014, 'Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae', eLife, vol. 3, pp. e01434, http://dx.doi.org/10.7554/eLife.01434
Han SP; Gambin Y; Gomez GA; Verma S; Giles N; Michael M; Wu SK; Guo Z; Johnston W; Sierecki E, 2014, 'Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens', Journal of Biological Chemistry, vol. 289, pp. 7764 - 7775, http://dx.doi.org/10.1074/jbc.M113.544478
Brooks AJ; Dai W; O'Mara ML; Abankwa D; Chhabra Y; Pelekanos RA; Gardon O; Tunny KA; Blucher KM; Morton CJ, 2014, 'Mechanism of activation of protein kinase JAK2 by the growth hormone receptor', Science, vol. 344, http://dx.doi.org/10.1126/science.1249783
Sierecki E; Stevers LM; Giles N; Polinkovsky ME; Moustaqil M; Mureev S; Johnston WA; Dahmer-Heath M; Skalamera D; Gonda TJ, 2014, 'Rapid mapping of interactions between human SNX-BAR proteins measured in vitro by alphascreen and single-molecule spectroscopy', Molecular and Cellular Proteomics, vol. 13, pp. 2233 - 2245, http://dx.doi.org/10.1074/mcp.M113.037275
Polinkovsky ME; Gambin Y; Banerjee PR; Erickstad MJ; Groisman A; Deniz AA, 2014, 'Ultrafast cooling reveals microsecond-scale biomolecular dynamics', Nature Communications, vol. 5, http://dx.doi.org/10.1038/ncomms6737
Martin S; Papadopulos A; Tomatis VM; Sierecki E; Malintan NT; Gormal RS; Giles N; Johnston WA; Alexandrov K; Gambin Y, 2014, 'Increased polyubiquitination and proteasomal degradation of a Munc18-1 disease-linked mutant causes temperature-sensitive defect in exocytosis', Cell Reports, vol. 9, pp. 206 - 218, http://dx.doi.org/10.1016/j.celrep.2014.08.059
Gambin Y; Ariotti N; McMahon KA; Bastiani M; Sierecki E; Kovtun O; Polinkovsky ME; Magenau A; Jung WR; Okano S, 2014, 'Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae', eLife, vol. 2014, http://dx.doi.org/10.7554/eLife.01434.001
Sierecki E; Giles N; Polinkovsky M; Moustaqil M; Alexandrov K; Gambin Y, 2013, 'A cell-free approach to accelerate the study of protein-protein interactions in vitro', Interface Focus, vol. 3, http://dx.doi.org/10.1098/rsfs.2013.0018
Tnimov Z; Guo Z; Gambin Y; Nguyen UTT; Wu YW; Abankwa D; Stigter A; Collins BM; Waldmann H; Goody RS, 2012, 'Quantitative analysis of prenylated RhoA interaction with its chaperone, RhoGDI', Journal of Biological Chemistry, vol. 287, pp. 26549 - 26562, http://dx.doi.org/10.1074/jbc.M112.371294
Ferreon ACM; Moosa MM; Gambin Y; Deniz AA, 2012, 'Counteracting chemical chaperone effects on the single-molecule α-synuclein structural landscape', Proceedings of the National Academy of Sciences of the United States of America, vol. 109, pp. 17826 - 17831, http://dx.doi.org/10.1073/pnas.1201802109
Milles S; Koehler C; Gambin Y; Deniz AA; Lemke EA, 2012, 'Intramolecular three-colour single pair FRET of intrinsically disordered proteins with increased dynamic range', Molecular BioSystems, vol. 8, pp. 2531 - 2534, http://dx.doi.org/10.1039/c2mb25135c
Gambin Y; Vandelinder V; Ferreon ACM; Lemke EA; Groisman A; Deniz AA, 2011, 'Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing', Nature Methods, vol. 8, pp. 239 - 241, http://dx.doi.org/10.1038/nmeth.1568
Gambin Y; Simonnet C; Vandelinder V; Deniz A; Groisman A, 2010, 'Ultrafast microfluidic mixer with three-dimensional flow focusing for studies of biochemical kinetics', Lab on a Chip, vol. 10, pp. 598 - 609, http://dx.doi.org/10.1039/b914174j
Gambin Y; Reffay M; Sierecki E; Homblé F; Hodges RS; Gov NS; Taulier N; Urbach W, 2010, 'Variation of the lateral mobility of transmembrane peptides with hydrophobic mismatch', Journal of Physical Chemistry B, vol. 114, pp. 3559 - 3566, http://dx.doi.org/10.1021/jp911354y
Gambin Y; Deniz AA, 2010, 'Multicolor single-molecule FRET to explore protein folding and binding', Molecular BioSystems, vol. 6, pp. 1540 - 1547, http://dx.doi.org/10.1039/c003024d
Ferreon ACM; Moran CR; Gambin Y; Deniz AA, 2010, 'Single-molecule fluorescence studies of intrinsically disordered proteins.', Methods in enzymology, vol. 472, pp. 179 - 204
Lemke EA; Gambin Y; Vandelinder V; Brustad EM; Liu HW; Schultz PG; Groisman A; Deniz AA, 2009, 'Microfluidic device for single-molecule experiments with enhanced photostability', Journal of the American Chemical Society, vol. 131, pp. 13610 - 13612, http://dx.doi.org/10.1021/ja9027023
Vandelinder V; Ferreon ACM; Gambin Y; Deniz AA; Groisman A, 2009, 'High-resolution temperature-concentration diagram of α-synuclein conformation obtained from a single Förster resonance energy transfer image in a microfluidic device', Analytical Chemistry, vol. 81, pp. 6929 - 6935, http://dx.doi.org/10.1021/ac901008c
Ferreon ACM; Gambin Y; Lemke EA; Deniz AA, 2009, 'Interplay of α-synuclein binding and conformational switching probed by single-molecule fluorescence', Proceedings of the National Academy of Sciences of the United States of America, vol. 106, pp. 5645 - 5650, http://dx.doi.org/10.1073/pnas.0809232106
Reffay M; Gambin Y; Benabdelhak H; Phan G; Taulier N; Ducruix A; Hodges RS; Urbach W, 2009, 'Tracking membrane protein association in model membranes', PLoS ONE, vol. 4, http://dx.doi.org/10.1371/journal.pone.0005035
Gambin Y; Schug A; Lemke EA; Lavinder JJ; Ferreon ACM; Magliery TJ; Onuchic JN; Deniz AA, 2009, 'Direct single-molecule observation of a protein living in two opposed native structures', Proceedings of the National Academy of Sciences of the United States of America, vol. 106, pp. 10153 - 10158, http://dx.doi.org/10.1073/pnas.0904461106
López-Esparza R; Guedeau-Boudeville M-A; Gambin Y; Rodríguez-Beas C; Maldonado A; Urbach W, 2006, 'Interaction between poly(ethylene glycol) and two surfactants investigated by diffusion coefficient measurements.', J Colloid Interface Sci, vol. 300, pp. 105 - 110, http://dx.doi.org/10.1016/j.jcis.2006.03.071
López-Esparza R; Guedeau-Boudeville MA; Gambin Y; Rodríguez-Beas C; Maldonado A; Urbach W, 2006, 'Interaction between poly(ethylene glycol) and two surfactants investigated by diffusion coefficient measurements', Journal of Colloid and Interface Science, vol. 300, pp. 105 - 110, http://dx.doi.org/10.1016/j.jcis.2006.03.071
Gambin Y; Legrand O; Quake SR, 2006, 'Microfabricated rubber microscope using soft solid immersion lenses', Applied Physics Letters, vol. 88, http://dx.doi.org/10.1063/1.2194477
Gambin Y; Lopez-Esparza R; Reffay M; Sierecki E; Gov NS; Genest M; Hodges RS; Urbach W, 2006, 'Lateral mobility of proteins in liquid membranes revisited', Proceedings of the National Academy of Sciences of the United States of America, vol. 103, pp. 2098 - 2102, http://dx.doi.org/10.1073/pnas.0511026103
Gambin Y; Massiera G; Ramos L; Ligoure C; Urbach W, 2005, 'Bounded step superdiffusion in an oriented hexagonal phase', Physical Review Letters, vol. 94, http://dx.doi.org/10.1103/PhysRevLett.94.110602
Michel E; Cipelletti L; d’Humieres E; Gambin Y; Urbach W; Porte G; Appell J, 2002, 'Self-diffusion and collective diffusion in a model viscoelastic system', Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics, vol. 66, http://dx.doi.org/10.1103/PhysRevE.66.031402
Conference Papers
Brooks AJ; O'Mara ML; Dai W; Abankwa D; Chhabra Y; Tunny KA; Parker MW; Sierecki E; Gambi Y; Gomez GA, 2016, 'Mechanism of JAK2 Activation by the Archetype Class I Cytokine Receptor, the Growth Hormone Receptor', in BIOPHYSICAL JOURNAL, CELL PRESS, Los Angeles, CA, pp. 31A - 31A, presented at 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, 27 February - 02 March 2016, http://dx.doi.org/10.1016/j.bpj.2015.11.233
Moustaqil M; Overman J; Fontaine F; Bailey T; Francois M; Gambin Y; Sierecki E, 2016, 'Establishing a transcription factors protein network for lymphangiogenesis: identification of binding domains, impact of pathological mutations and perturbations by small molecules', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444003094&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Giles N; McCann A; Moustaqil M; Overman J; Fontaine F; Francois M; Sierecki E; Gambin Y, 2016, 'Tracking Dynamics of Vascular Development in Time and Space using Sox18 Dimer split-Fluorescent Protein Biosensors', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444006122&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Gambin Y; Sierecki E; Jung W; Ariotti N; Giles N; Bastiani M; Parton R, 2016, 'Redefining caveolae as signalling platforms: specificity of interactions on endocytic caveolae in response to stress', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444006522&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Moustaqil M; Overman J; Fontaine F; Bailey T; Francois M; Gambin Y; Sierecki E, 2016, 'Establishing a transcription factors protein network for lymphangiogenesis: identification of binding domains, impact of pathological mutations and perturbations by small molecules', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444005311&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Giles N; McCann A; Moustaqil M; Overman J; Fontaine F; Francois M; Sierecki E; Gambin Y, 2016, 'Tracking Dynamics of Vascular Development in Time and Space using Sox18 Dimer split-Fluorescent Protein Biosensors', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444003324&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Gambin Y; Sierecki E; Jung W; Ariotti N; Giles N; Bastiani M; Parton R, 2016, 'Redefining caveolae as signalling platforms: specificity of interactions on endocytic caveolae in response to stress', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444003550&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Brooks A; Dai W; O'Mara ML; Abankwa D; Chhabra Y; Pelekanos RA; Gardon O; Tunny KA; Blucher KM; Morton CJ, 2016, 'Going downstream - how does GH binding activate JAK2', in CLINICAL ENDOCRINOLOGY, WILEY-BLACKWELL, Adelaide, AUSTRALIA, pp. 16 - 16, presented at Annual Scientific Meeting of the Endocrine-Society-of-Australia, Adelaide, AUSTRALIA, 23 - 26 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372310400043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
O'Carroll A; Ve T; Lau D; Giles N; Moustaqil M; Bhumkar A; Hunter D; Kobe B; Boecking T; Sierecki E, 2016, 'Prion - like protein polymerisation underlies signal transduction in innate immunity: the emergence of a universal mechanism ?', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444005435&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
O'Carroll A; Ve T; Lau D; Giles N; Moustaqil M; Bhumkar A; Hunter D; Kobe B; Boecking T; Sierecki E, 2016, 'Prion - like protein polymerisation underlies signal transduction in innate immunity: the emergence of a universal mechanism ?', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444003010&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Bhumkar A; Gambin Y; Leitao A; Bowden Q; Giles N; Francois B; Hunter D; Boecking T; Sierecki E, 2016, 'What pathological mutants tell us about synuclein aggregation pathways', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444003009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Bhumkar A; Gambin Y; Leitao A; Bowden Q; Giles N; Francois B; Hunter D; Boecking T; Sierecki E, 2016, 'What pathological mutants tell us about synuclein aggregation pathways', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 02 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444005434&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Brooks AJ; Chhabra Y; Abankwa D; O'Mara M; Dai W; Gardon O; Tunny KA; Blucher KM; Morton CJ; Parker MW, 2014, 'A new cytokine receptor activation paradigm: Activation of JAK2 by the growth hormone receptor', in CYTOKINE, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Melbourne, AUSTRALIA, pp. 22 - 22, presented at 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne, AUSTRALIA, 26 - 29 October 2014, http://dx.doi.org/10.1016/j.cyto.2014.07.227
Giles N; Sierecki E; Polinkovsky M; Schroder K; Alexandrov K; Gambin Y, 2014, 'A novel approach to investigate the assembly of the NOD-like receptor inflammasomes', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 26 - 30 April 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346646700166&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Sierecki E; Polinkovsky M; Giles N; Moustaqil M; Alexandrov K; Gambin Y, 2014, 'Probing the architecture of the Mediator complex', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346651003484&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Polinkovsky M; Sierecki E; Giles N; Alexandrov K; Gambin Y, 2014, 'Uncovering transcription factor binding pockets in the tail subdomain of the human mediator complex', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346651004001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Polinkovsky ME; Gambin Y; Erickstad M; Deniz A; Groisman A, 2012, 'Inverse Temperature Jump System to Study Fast Protein Folding Kinetics', in BIOPHYSICAL JOURNAL, CELL PRESS, San Diego, CA, pp. 448A - 449A, presented at 56th Annual Meeting of the Biophysical-Society, San Diego, CA, 25 - 29 February 2012, http://dx.doi.org/10.1016/j.bpj.2011.11.2460
Moran CR; Ferreon ACM; Gambin Y; Deniz AA, 2010, 'Single-Molecule FRET Reveals Altered Binding-Induced Folding Landscape of PD-Related Mutant Protein Alpha-Synuclein', in BIOPHYSICAL JOURNAL, CELL PRESS, pp. 258A - 258A, http://dx.doi.org/10.1016/j.bpj.2009.12.1402
Gambin Y; Reffay M; Sierecki E; Homble F; Genest M; Hodges RS; Gov N; Taulier N; Urbach W, 2010, 'Modulation of the Lateral Mobility of Transmembrane Peptides with Hydrophobic Mismatch', in BIOPHYSICAL JOURNAL, CELL PRESS, pp. 224A - 225A, http://dx.doi.org/10.1016/j.bpj.2009.12.1215
Gambin Y; Lemke EA; Vandelinder V; Groisman A; Deniz AA, 2010, 'High-Resolution smFRET in a Microfluidic Gas Exchange Platform', in BIOPHYSICAL JOURNAL, CELL PRESS, pp. 622A - 623A, http://dx.doi.org/10.1016/j.bpj.2009.12.3407
Schug A; Gambin Y; Deniz A; Onuchic J, 2009, 'The Rop-Dimer: A Folded Protein Living Between Two Alternate Structures', in BIOPHYSICAL JOURNAL, CELL PRESS, pp. 568A - 568A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426362200013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Abstracts
Sierecki E; Brown J; Leitao A; Chappard A; Gambin Y, 2018, 'The Shifting Interactome of Alpha-Synuclein along its Aggregation Pathway', in PROTEIN SCIENCE, WILEY, Boston, MA, Vol. 27, pp. 73 - 73, presented at 32nd Annual Symposium of the Protein-Society, Boston, MA, 09 - 12 July 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000450682700119&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
O'Carroll A; Ve T; Moustaqil M; Giles N; Bhumkar A; Hunter D; Kobe B; Sierecki E; Gambin Y, 2017, 'Prion - like protein polymerisation underlies signal transduction in innate immunity: The emergence of a universal mechanism ?', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Chicago, IL, Vol. 31, presented at Annual Meeting of the American-Society-for-Pharmacology-and-Experimental-Therapeutics (ASPET) at Experimental Biology Meeting, Chicago, IL, 22 - 26 April 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000405461402427&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
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