Dr Vashe Chandrakanthan

Tavassoli H; Rorimpandey P; Kang YC; Carnell M; Brownlee C; Pimanda J; Chan PPY; Chandrakanthan V, 2020, 'Label-free Isolation and Single Cell Biophysical Phenotyping Analysis of Primary Cardiomyocytes Using Inertial Microfluidics', , http://dx.doi.org/10.1101/2020.08.31.243592

Tavassoli H; Kang YC; Rorimpandey P; Pimanda J; Chandrakanthan V; Chan PPY, 2020, 'Capturing Neonatal Cardiomyocyte – Endothelial interactions on-a-Chip', , http://dx.doi.org/10.1101/2020.08.10.243600

Yeola A; Subramanian S; Oliver R; Lucas C; Thoms J; Yan F; Olivier J; Chacon D; Tursky M; Hung T; Power C; Hardy P; Ma D; McCarroll J; Kavallaris M; Hesson L; Beck D; Curtis D; Wong JWH; Hardeman E; Walsh W; Mobbs R; Chandrakanthan V; Pimanda J, 2020, 'Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine', , http://dx.doi.org/10.1101/2020.06.04.130872

Williamson A; Toledo DF; Schwarz N; Fernando S; Dimasi C; Liyanage S; Skoumbourdis T; Chandrakanthan V; Di Bartolo B; Tan JTM; Bonder CS; Nicholls SJ; Bursill CA; Psaltis PJ, 2019, 'P5384Postnatal mouse aorta contains yolk sac-derived haemangioblasts with myeloid and endothelial plasticity and vasculogenic capacity', European Heart Journal, vol. 40, http://dx.doi.org/10.1093/eurheartj/ehz746.0344

Williamson A; Toledo D; Schwarz N; Fernando S; Dimasi C; Liyanage S; Skoumbourdis T; Chandrakanthan V; Tan J; Bonder C; Di Bartolo B; Nicholls S; Bursill C; Psaltis P, 2019, 'Postnatal Mouse Aorta Contains Yolk Sac-Derived Haemangioblasts with Myeloid and Endothelial Plasticity and Vasculogenic Capacity', Heart, Lung and Circulation, vol. 28, pp. S330 - S331, http://dx.doi.org/10.1016/j.hlc.2019.06.455

Unnikrishnan A; Papaemmanuil E; Beck D; Deshpande NP; Verma A; Kumari A; Woll PS; Richards LA; Knezevic K; Chandrakanthan V; Thoms JAI; Tursky ML; Huang Y; Ali Z; Olivier J; Galbraith S; Kulasekararaj AG; Tobiasson M; Karimi M; Pellagatti A; Wilson SR; Lindeman R; Young B; Ramakrishna R; Arthur C; Stark R; Crispin P; Curnow J; Warburton P; Roncolato F; Boultwood J; Lynch K; Jacobsen SEW; Mufti GJ; Hellstrom-Lindberg E; Wilkins MR; MacKenzie KL; Wong JWH; Campbell PJ; Pimanda JE, 2017, 'Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes', Cell Reports, vol. 20, pp. 572 - 585, http://dx.doi.org/10.1016/j.celrep.2017.06.067

Chandrakanthan V; Qiao Q; Chan Kang Y; Knezevic K; Oliver R; Loo C; Anande G; Lee B; Walsh W; Power C; Wong J; Pimanda J, 2017, 'Declined presentation characterisation of stromal cell populations in the foetal liver and their contributions to embryonic haematopoietic and vascular development', Experimental Hematology, vol. 53, pp. S118 - S118, http://dx.doi.org/10.1016/j.exphem.2017.06.295

Huang Y; Thoms JAI; Tursky ML; Knezevic K; Beck D; Chandrakanthan V; Suryani S; Olivier J; Boulton A; Glaros EN; Thomas SR; Lock RB; MacKenzie KL; Bushweller JH; Wong JWH; Pimanda JE, 2016, 'MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation', Leukemia, vol. 30, pp. 1552 - 1561, http://dx.doi.org/10.1038/leu.2016.55

Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A; Villanueva JE; Nunez AC; Knezevic K; Palu C; Nasrallah R; Carnell M; Macmillan A; Whan R; Yu Y; Hardy P; Grey ST; Gladbach A; Delerue F; Ittner L; Mobbs R; Walkley CR; Purton LE; Ward RL; Wong JWH; Hesson LB; Walsh W; Pimanda JE, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113

Thoms JAI; Knezevic K; Liu JJ; Glaros EN; Thai T; Qiao Q; Campbell H; Packham D; Huang Y; Papathanasiou P; Tunningley R; Whittle B; Yeung AWS; Chandrakanthan V; Hesson L; Chen V; Wong JWH; Purton LE; Ward RL; Thomas SR; Pimanda JE, 2016, 'Arrested hematopoiesis and vascular relaxation defects in mice with a mutation in Dhfr', Molecular and Cellular Biology, vol. 36, pp. 1222 - 1236, http://dx.doi.org/10.1128/MCB.01035-15

Rao TN; Marks-Bluth J; Sullivan J; Gupta MK; Chandrakanthan V; Fitch SR; Ottersbach K; Jang YC; Piao X; Kulkarni RN; Serwold T; Pimanda JE; Wagers AJ, 2015, 'High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice', Stem Cell Research, vol. 14, pp. 307 - 322, http://dx.doi.org/10.1016/j.scr.2015.02.001

Marks-Bluth J; Khanna A; Chandrakanthan V; Thoms J; Bee T; Eich C; Kang YC; Knezevic K; Qiao Q; Fitch S; Oxburgh L; Ottersbach K; Dzierzak E; de Bruijn MFTR; Pimanda JE, 2015, 'SMAD1 and SMAD5 expression is coordinately regulated by FLI1 and GATA2 during endothelial development', Molecular and Cellular Biology, vol. 35, pp. 2165 - 2172, http://dx.doi.org/10.1128/MCB.00239-15

Pelekanos RA; Li J; Gongora M; Chandrakanthan V; Scown J; Suhaimi N; Brooke G; Christensen ME; Doan T; Rice AM; Osborne GW; Grimmond SM; Harvey RP; Atkinson K; Little MH, 2012, 'Corrigendum to "Comprehensive transcriptome and immunophenotype analysis of renal and cardiac MSC-like populations supports strong congruence with bone marrow MSC despite maintenance of distinct identities" [Stem Cell. 8 (2012) 58-73]', Stem Cell Research, vol. 9, pp. 58, http://dx.doi.org/10.1016/j.scr.2012.02.003

Biben C; Chandrakanthan V; Menon MK; Harvey R; Prall O, 2012, 'PDGFRA is essential for the development of a novel cardiac cell type with stem-like properties', Pathology, vol. 44, pp. S56 - S56, http://dx.doi.org/10.1016/s0031-3025(16)32738-6

Biben C; Chandrakanthan V; Menon MK; Harvey R; Prall O, 2012, 'PDGFRA is essential for the development of a novel cardiac cell type with stem-like properties', Pathology, vol. 44, pp. S63 - S63, http://dx.doi.org/10.1016/s0031-3025(16)32758-1

Pelecanos A; Li J; Gongora M; Chandrakanthan V; Scown J; Suhaimi M; Brooke G; Christensen ME; Doan T; Rice AM; Osborne GW; Grimmond S; Harvey RP; Atkinson K; Little MH, 2011, 'Comprehensive transcriptome and immunophenotype analysis of renal and cardiac MSC-like populations supports strong congruence with bone marrow MSC despite maintenance of distinct identities', Cell Stem Cell, vol. 8, pp. 58 - 73, http://dx.doi.org/10.1016/j.scr.2011.08.003

Chong J; Chandrakanthan V; Xaymardan M; Asli NS; Li J; Ahmed I; Heffernan C; Menon M; Scarlett C; Rashidianfar A; Biben C; Zoellner H; Colvin EK; Pimanda JE; Biankin AV; Zhou B; Pu WT; Prall OWJ; Harvey RP, 2011, 'Adult cardiac-resident MSC-like stem cells with a proepicardial origin', Cell Stem Cell, vol. 9, pp. 527 - 540, http://dx.doi.org/10.1016/j.stem.2011.10.002

Jin XL; Chandrakanthan V; Morgan HD; O'Neill C, 2009, 'Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway (Biology of Reproduction (2009) 80, (286-294) DOI: 10.1095/biolreprod.108.070102)', Biology of Reproduction, vol. 81, pp. 233 - 242, http://dx.doi.org/10.1095/biolreprod.109.078444

Jin XL; Chandrakanthan V; Morgan HD; O'Neill C, 2009, 'Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway.', Biology of reproduction, vol. 81, pp. 234 - 242

Jin XL; Chandrakanthan V; Morgan HD; O'Neill C, 2009, 'Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway', Biology of Reproduction, vol. 80, pp. 286 - 294, http://dx.doi.org/10.1095/biolreprod.108.070102

Chong J; Prall O; Chandrakanthan V; Xaymardan M; Ahmed I; Scarlett C; Colvin E; Pinese M; Biankin A; Harvey R, 2009, 'Sca1+/CD31−/PDGFRa+ Cardiac Stem Cells are from an Epicardial/Mesodermal but not Neural-crest, Cardiomyocyte or Bone-marrow Origin', Heart, Lung and Circulation, vol. 18, pp. S3 - S3, http://dx.doi.org/10.1016/j.hlc.2009.05.005

Jin X; Chandrakanthan V; O.'Neill C, 2008, '427. MDM2 maintains the latency of expression of TRP53 in the mouse preimplantation embryo', Reproduction, Fertility and Development, vol. 20, pp. 107 - 107, http://dx.doi.org/10.1071/srb08abs427

Li Y; Chandrakanthan V; Day ML; O'Neill C, 2007, 'Direct evidence for the action of phosphatidylinositol (3,4,5)- trisphosphate-mediated signal transduction in the 2-cell mouse embryo', Biology of Reproduction, vol. 77, pp. 813 - 821, http://dx.doi.org/10.1095/biolreprod.107.060129

Chandrakanthan V; Chami O; Stojanov T; O'Neill C, 2007, 'Variable expressivity of the tumour suppressor protein TRP53 in cryopreserved human blastocysts', Reproductive Biology and Endocrinology, vol. 5, http://dx.doi.org/10.1186/1477-7827-5-39

Li A; Chandrakanthan V; Chami O; O'Neill C, 2007, 'Erratum: Culture of zygotes increases TRP53 expression in B6 mouse embryos, which reduces embryo viability (Biology of Reproduction (2007) 76, (362-367) DOI: 10.1095/biolreprod.106.056838)', Biology of Reproduction, vol. 76, pp. 924, http://dx.doi.org/10.1095/biolreprod.107.061853

Li A; Chandrakanthan V; Chami O; O'Neill C, 2007, 'Culture of zygotes increases p53 expression in B6 mouse embryos, which reduces embryo viability', Biology of Reproduction, vol. 76, pp. 362 - 367, http://dx.doi.org/10.1095/biolreprod.106.056838

Chandrakanthan V; Li A; Chami O; O'Neill C, 2006, 'Effects of in vitro fertilization and embryo culture on TRP53 and Bax expression in B6 mouse embryos', Reproductive Biology and Endocrinology, vol. 4, http://dx.doi.org/10.1186/1477-7827-4-4

O'Neill C; Li A; Chandrakanthan V, 2005, 'IVF or culture of embryos in vitro causes increased p53 expression which compromises their developmental competence.', FERTILITY AND STERILITY, vol. 84, pp. S386 - S386, http://dx.doi.org/10.1016/j.fertnstert.2005.07.1009

Lu DP; Chandrakanthan V; Cahana A; Ishii S; O'Neill C, 2004, 'Trophic signals acting via phosphatidylinositol-3 kinase are required for normal pre-implantation mouse embryo development', Journal of Cell Science, vol. 117, pp. 1567 - 1576, http://dx.doi.org/10.1242/jcs.00991

Asli NS; Xaymardan M; Patrick R; Farbehi N; Cornwell J; Forte E; Waardenberg AJ; Janbandhu V; Kesteven S; Chandrakanthan V; Malinowska H; Reinhard H; Schofield P; Christ D; Ahmed I; Bouveret R; Srivastava S; Mishra RK; Dhawan J; Chong JJH; Nordon R; Macdonald P; Graham RM; Feneley M; Harvey RP, 'PDGFRα signaling in cardiac fibroblasts modulates quiescence, metabolism and self-renewal, and promotes anatomical and functional repair', , http://dx.doi.org/10.1101/225979