Dr Tim Murphy
Fields of research: Cardiology (incl. Cardiovascular Diseases), Cardiovascular Medicine and Haematology
Contact Details
Phone: +61 2 9385 3600
Fax: 51059
Email: tim.murphy@unsw.edu.au
Supervision
- ILP
- PHD
- Masters
- Honours
Tabs
Publications related to this Person
Journal articles
Murphy TV; Sandow SL, 2019, 'Agonist-evoked endothelial Ca 2+ signalling microdomains', Current Opinion in Pharmacology, vol. 45, pp. 8 - 15, http://dx.doi.org/10.1016/j.coph.2019.03.005
Grayson TH; Murphy TV; Sandow SL, 2017, 'Transient receptor potential canonical type 3 channels: Interactions, role and relevance - A vascular focus', Pharmacology and Therapeutics, vol. 174, pp. 79 - 96, http://dx.doi.org/10.1016/j.pharmthera.2017.02.022
Quek KJ; Boyd R; Ameer OZ; Zangerl B; Butlin M; Murphy TV; Avolio AP; Phillips JK, 2016, 'Progressive vascular remodelling, endothelial dysfunction and stiffness in mesenteric resistance arteries in a rodent model of chronic kidney disease', Vascular Pharmacology, vol. 81, pp. 42 - 52, http://dx.doi.org/10.1016/j.vph.2015.12.004
Murphy TV; Kanagarajah A; Toemoe S; Bertrand PP; Grayson TH; Britton FC; Leader L; Senadheera S; Sandow SL, 2016, 'TRPV3 expression and vasodilator function in isolated uterine radial arteries from non-pregnant and pregnant rats', Vascular Pharmacology, vol. 83, pp. 66 - 77, http://dx.doi.org/10.1016/j.vph.2016.04.004
Kerr PM; Wei R; Tam R; Sandow SL; Murphy TV; Ondrusova K; Lunn SE; Tran CHT; Welsh DG; Plane F, 2015, 'Activation of endothelial IK
Holobotovskyy V; Chong YS; Burchell J; He B; Phillips M; Leader L; Murphy TV; Sandow SL; McKitrick DJ; Charles AK, 2015, 'Regulator of G protein signaling 5 is a determinant of gestational hypertension and preeclampsia', Science Translational Medicine, vol. 7, http://dx.doi.org/10.1126/scitranslmed.aaa5038
Howitt L; Morris MJ; Sandow SL; Murphy TV, 2014, 'Effect of diet-induced obesity on BK
Ellinsworth DC; Earley S; Murphy TV; Sandow SL, 2014, 'Endothelial control of vasodilation: Integration of myoendothelial microdomain signalling and modulation by epoxyeicosatrienoic acids', Pflugers Archiv European Journal of Physiology, vol. 466, pp. 389 - 405, http://dx.doi.org/10.1007/s00424-013-1303-3
Wang K; Bertrand RL; Senadheera S; Polglaze KE; Murphy TV; Sandow SL; Liu L; Bornstein JC; Bertrand PP, 2014, 'Motility changes induced by intraluminal FeSO
Senadheera S; Bertrand PP; Grayson TH; Leader L; Murphy TV; Sandow SL, 2013, 'Pregnancy-induced remodelling and enhanced endothelium-derived hyperpolarization-type vasodilator activity in rat uterine radial artery: Transient receptor potential vanilloid type 4 channels, caveola', Journal of Anatomy, vol. 223, pp. 677 - 686, http://dx.doi.org/10.1111/joa.12127
Senadheera S; Bertrand PP; Grayson TH; Leader L; Tare M; Murphy TV; Sandow SL, 2013, 'Enhanced contractility in pregnancy is associated with augmented TRPC3, L-type, and T-type voltage-dependent calcium channel function in rat uterine radial artery', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, vol. 305, http://dx.doi.org/10.1152/ajpregu.00225.2013
Naser M; Januszeski AS; Brown BE; Jenkins AJ; Hill MA; Murphy TV, 2013, 'Advanced glycation end products acutely impair Ca2+ signaling in bovine aortic endothelial cells', Frontiers in Physiology, vol. 4, pp. Article No. 38, http://dx.doi.org/10.3389/fphys.2013.00038
Grayson TH; Chadha PS; Bertrand PP; Chen H; Morris MJ; Senadheera S; Murphy TV; Sandow SL, 2013, 'Increased caveolae density and caveolin-1 expression accompany impaired NO-mediated vasorelaxation in diet-induced obesity', Histochemistry and Cell Biology, vol. 139, pp. 309 - 321, http://dx.doi.org/10.1007/s00418-012-1032-2
Sandow SL; Senadheera S; Grayson TH; Welsh DG; Murphy TV, 2012, 'Calcium and endothelium-mediated vasodilator signaling', Advances in Experimental Medicine and Biology, vol. 740, pp. 811 - 831, http://dx.doi.org/10.1007/978-94-007-2888-2_36
Sandow SL; Senadheera S; Bertrand PP; Murphy TV; Tare M, 2012, 'Myoendothelial Contacts, Gap Junctions, and Microdomains: Anatomical Links to Function?', Microcirculation, vol. 19, pp. 403 - 415, http://dx.doi.org/10.1111/j.1549-8719.2011.00146.x
Howitt L; Hilton Grayson T; Morris MJ; Sandow SL; Murphy TV, 2012, 'Dietary obesity increases NO and inhibits BK
Bertrand RL; Senadheera S; Tanoto A; Tan KL; Howitt L; Chen H; Murphy TV; Sandow SL; Liu L; Bertrand PP, 2012, 'Serotonin availability in rat colon is reduced during a Western diet model of obesity', American Journal of Physiology - Gastrointestinal and Liver Physiology, vol. 303, http://dx.doi.org/10.1152/ajpgi.00048.2012
Senadheera S; Kim Y; Grayson TH; Toemoe S; Kochukov MY; Abramowitz J; Housley GD; Bertrand RL; Chadha PS; Bertrand PP, 2012, 'Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity', Cardiovascular Research, vol. 95, pp. 439 - 447, http://dx.doi.org/10.1093/cvr/cvs208
Howitt L; Sandow SL; Grayson TH; Ellis ZE; Morris MJ; Murphy TV, 2011, 'Differential effects of diet-induced obesity on BK
Bertrand RL; Senadheera S; Markus I; Liu L; Howitt L; Chen H; Murphy TV; Sandow SL; Bertrand PP, 2011, 'A western diet increases serotonin availability in rat small intestine', Endocrinology, vol. 152, pp. 36 - 47, http://dx.doi.org/10.1210/en.2010-0377
Chadha PS; Liu L; Rikard-Bell M; Senadheera S; Howitt L; Bertrand RL; Grayson TH; Murphy TV; Sandow SL, 2011, 'Endothelium-dependent vasodilation in human mesenteric artery is primarily mediated by myoendothelial gap junctions intermediate conductance calcium-activated K+ channel and nitric oxide', Journal of Pharmacology and Experimental Therapeutics, vol. 336, pp. 701 - 708, http://dx.doi.org/10.1124/jpet.110.165795
Murphy TV; Jenkins AJ; Hill MA; Naser N, 2010, 'Effect of advanced glycation end products on dilation of rat skeletal muscle arterioles', FASEB JOURNAL, vol. 24, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208675507367&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Sandow SL; Murphy TV, 2010, 'Under pressure - K
Chadha PS; Haddock RE; Howitt L; Morris MJ; Murphy TV; Grayson TH; Sandow SL, 2010, 'Obesity up-regulates intermediate conductance calcium-activated potassium channels and myoendothelial gap junctions to maintain endothelial vasodilator function', Journal of Pharmacology and Experimental Therapeutics, vol. 335, pp. 284 - 293, http://dx.doi.org/10.1124/jpet.110.167593
Yang Y; Murphy TV; Ella SR; Grayson TH; Haddock R; Hwang YT; Braun AP; Peichun G; Korthuis RJ; Davis MJ, 2009, 'Heterogeneity in function of small artery smooth muscle BK
Potocnik S; McSherry I; Ding H; Murphy TV; Kotecha N; Dora K; Yuill KH; Triggle C; Hill M, 2009, 'Endothelium-dependent Vasodilation in Myogenically Active Mouse Skeletal Muscle Arterioles: Role of EDH and K+ Channels', Microcirculation, vol. 16, pp. 377 - 390
Hill M; Murphy T; Gui P; Hwang Y; Howitt L; Davis M; Sun Z, 2007, 'Properties of the large conductance K+ channel (BKCa) in skeletal muscle arterioles', FASEB JOURNAL, vol. 21, pp. A846 - A846, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000245708700519&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Potocnik SJ; Jenkins N; Murphy TV; Hill MA, 2007, 'Membrane cholesterol depletion with β-cyclodextrin impairs pressure-induced contraction and calcium signalling in isolated skeletal muscle arterioles', Journal of Vascular Research, vol. 44, pp. 292 - 302, http://dx.doi.org/10.1159/000101451
Murphy TV; Kotecha N; Hill MA, 2007, 'Endothelium-independent constriction of isolated, pressurized arterioles by N ω-nitro-L-arginine methyl ester (L-NAME)', British Journal of Pharmacology, vol. 151, pp. 602 - 609, http://dx.doi.org/10.1038/sj.bjp.0707262
Murphy TV, 2007, 'I don't need this pressure on; Src-family kinases, ERK 1/2 kinase and mechanotransduction in arteries', Journal of Hypertension, vol. 25, pp. 1791 - 1793, http://dx.doi.org/10.1097/HJH.0b013e3282ef45f9
Murphy TV; Howitt L; Hill MA, 2006, 'Pharmacological characterization of potassium channels regulating arteriolar myogenic tone in vitro and in vivo', ACTA PHARMACOLOGICA SINICA, vol. 27, pp. 183 - 183, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000239590001425&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hill MA; Davis MJ; Meininger GA; Potocnik SJ; Murphy TV, 2006, 'Arteriolar myogenic signalling mechanisms: Implications for local vascular function', Clinical Hemorheology and Microcirculation, vol. 34, pp. 67 - 79
Spurrell BE; Murphy TV; Hill MA, 2003, 'Intraluminal pressure stimulates MAPK phosphorylation in arterioles: temporal dissociation from myogenic contractile response', American Journal of Physiology-Heart and Circulatory Physiology, vol. 285, pp. H1764 - H1773, http://dx.doi.org/10.1152/ajpheart.00468.2003
Davis MJ; Potocnik SJ; Murphy TV; Bishara NB; Rajanayagam MAS; Darby IA; Hill MA, 2003, 'Approaches for introducing peptides into intact and functional arteriolar smooth muscle: manipulation of protein kinase-based signalling', Clinical and Experimental Pharmacology and Physiology, vol. 30, pp. 653 - 658, http://dx.doi.org/10.1046/j.1440-1681.2003.03892.x
Bishara NB; Murphy TV; Hill MA, 2002, 'Capacitative Ca2+entry in vascular endothelial cells is mediatedviapathways sensitive to 2 aminoethoxydiphenyl borate and xestospongin C', British Journal of Pharmacology, vol. 135, pp. 119 - 128, http://dx.doi.org/10.1038/sj.bjp.0704465
Murphy TV; Spurrell BE; Hill MA, 2002, 'Mechanisms underlying pervanadate-induced contraction of rat cremaster muscle arterioles', European Journal of Pharmacology, vol. 442, pp. 107 - 114, http://dx.doi.org/10.1016/s0014-2999(02)01498-x
Murphy TV; Spurrell BE; Hill MA, 2002, 'Cellular Signalling In Arteriolar Myogenic Constriction: Involvement Of Tyrosine Phosphorylation Pathways', Clinical and Experimental Pharmacology and Physiology, vol. 29, pp. 612 - 619, http://dx.doi.org/10.1046/j.1440-1681.2002.03698.x
Bishara NB; Dunlop ME; Murphy TV; Darby IA; Sharmini Rajanayagam MA; Hill MA, 2002, 'Matrix protein glycation impairs agonist-induced intracellular Ca2+ signaling in endothelial cells', Journal of Cellular Physiology, vol. 193, pp. 80 - 92, http://dx.doi.org/10.1002/jcp.10153
Murphy TV; Spurrell BE; Hill MA, 2001, 'Tyrosine phosphorylation following alterations in arteriolar intraluminal pressure and wall tension.', American Journal of Physiology - Heart and Circulatory Physiology, vol. 281, pp. H1047 - H1056, http://ajpheart.physiology.org/content/281/3/H1047.long
Spurrell BE; Murphy TV; Hill MA, 2000, 'Tyrosine phosphorylation modulates arteriolar tone but is not fundamental to myogenic response.', American Journal of Physiology - Heart and Circulatory Physiology, vol. 278, pp. H373 - H382, http://ajpheart.physiology.org/content/278/2/H373.long
Potocnik SJ; Murphy TV; Kotecha N; Hill MA, 2000, 'Effects of mibefradil and nifedipine on arteriolar myogenic responsiveness and intracellular Ca2+', British Journal of Pharmacology, vol. 131, pp. 1065 - 1072, http://dx.doi.org/10.1038/sj.bjp.0703650
Murphy TV; Prountzos C; Kotsonis P; Iannazzo L; Majewski H, 1999, 'Structural determinants of phorbol ester binding in synaptosomes: pharmacokinetics and pharmacodynamics', European Journal of Pharmacology, vol. 381, pp. 77 - 84, http://dx.doi.org/10.1016/s0014-2999(99)00540-3
Binko J; Murphy TV; Majewski H, 1998, '17?-OESTRADIOL ENHANCES NITRIC OXIDE SYNTHASE ACTIVITY IN ENDOTHELIUM-DENUDED RAT AORTA', Clinical and Experimental Pharmacology and Physiology, vol. 25, pp. 120 - 127, http://dx.doi.org/10.1111/j.1440-1681.1998.tb02188.x
Majewski H; Kotsonis P; Murphy TV; Barrington M, 1997, 'Noradrenaline release and the effect of endogenous activation of the phospholipase C/protein kinase C signalling pathway in rat atria', British Journal of Pharmacology, vol. 121, pp. 1196 - 1202, http://dx.doi.org/10.1038/sj.bjp.0701236
Majewski H; Kotsonis P; Iannazzo L; Murphy TV; Musgrave IF, 1997, 'PROTEIN KINASE C AND TRANSMITTER RELEASE.', Clinical and Experimental Pharmacology and Physiology, vol. 24, pp. 619 - 623, http://dx.doi.org/10.1111/j.1440-1681.1997.tb02102.x
Murphy TV; Garland CJ, 1995, 'Specific accumulation of inositol 1,4,5-trisphosphate in rabbit basilar artery in response to noradrenaline but not 5-hydroxytryptamine', European Journal of Pharmacology: Molecular Pharmacology, vol. 290, pp. 141 - 144, http://dx.doi.org/10.1016/0922-4106(95)90026-8
Murphy TV; Broad LM; Garland CJ, 1995, 'Characterisation of inositol 1,4,5-trisphosphate binding sites in rabbit aortic smooth muscle', European Journal of Pharmacology: Molecular Pharmacology, vol. 290, pp. 145 - 150, http://dx.doi.org/10.1016/0922-4106(95)90027-6
Seager JM; Murphy TV; Garland CJ, 1994, 'Importance of inositol (1,4,5)-trisphosphate, intracellular Ca2+ release and myofilament Ca2+ sensitization in 5-hydroxytryptamine-evoked contraction of rabbit mesenteric artery', British Journal of Pharmacology, vol. 111, pp. 525 - 532, http://dx.doi.org/10.1111/j.1476-5381.1994.tb14769.x
Murphy TV; Cross KML; Dunning PM; Garland CJ, 1994, 'Phorbol esters impair endothelium-dependent and independent relaxation in rat aortic rings', General Pharmacology: The Vascular System, vol. 25, pp. 581 - 588, http://dx.doi.org/10.1016/0306-3623(94)90218-6
Murphy TV; Foucart S; Majewski H, 1992, 'Prejunctional α2-adrenoceptors in mouse atria function through G-proteins which are sensitive to N-ethylmaleimide, but not pertussis toxin', British Journal of Pharmacology, vol. 106, pp. 871 - 876, http://dx.doi.org/10.1111/j.1476-5381.1992.tb14427.x
Murphy TV; Majewski H, 1990, 'Pertussis toxin differentiates between α1- and α2-adrenoceptor-mediated inhibition of noradrenaline release from rat kidney cortex', European Journal of Pharmacology, vol. 179, pp. 435 - 439, http://dx.doi.org/10.1016/0014-2999(90)90185-9
Murphy TV; Majewski H, 1990, 'PERTUSSIS TOXIN ATTENUATES ANGIOTENSIN II BUT NOT ?-ADRENOCEPTOR FACILITATION OF NORADRENALINE RELEASE FROM RAT KIDNEY CORTEX', Clinical and Experimental Pharmacology and Physiology, vol. 17, pp. 521 - 526, http://dx.doi.org/10.1111/j.1440-1681.1990.tb01352.x
MAJEWSKI H; COSTA M; FOUCART S; MURPHY TV; MUSGRAVE IF, 1990, 'Second Messengers Are Involved in Facilitatory but Not Inhibitory Receptor Actions at Sympathetic Nerve Endings', Annals of the New York Academy of Sciences, vol. 604, pp. 266 - 275, http://dx.doi.org/10.1111/j.1749-6632.1990.tb31999.x
Foucart S; Murphy TV; Majewski H, 1990, 'Prejunctional β-adrenoceptors, angiotensin II and neuropeptide Y receptors on sympathetic nerves in mouse atria are linked to N-ethylmaleimide-susceptible G-proteins', Journal of the Autonomic Nervous System, vol. 30, pp. 221 - 232, http://dx.doi.org/10.1016/0165-1838(90)90253-f
Majewski H; Murphy TV, 1989, 'Beta-adrenoceptor blockade and sympathetic neurotransmission in the pithed rat', Journal of Hypertension, vol. 7, pp. 991 - 996, http://dx.doi.org/10.1097/00004872-198912000-00010
Conference Papers
Kerr PM; Wei R; Lunn SE; Gust SL; Classen B; Murphy TV; Sandow SL; Plane F, 2017, 'The Functional Contribution Of Myoendothelial Feedback To Arterial Tone Is Determined By The Nature Of The Vasoconstricion', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Chicago, IL, presented at Annual Meeting of the American-Society-for-Pharmacology-and-Experimental-Therapeutics (ASPET) at Experimental Biology Meeting, Chicago, IL, 22 - 26 April 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000405986505412&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Sandow SL; Jones NM; Nguyen HL; Ellinsworth D; Grayson TH; Grimley R; Dettrick A; Murphy TV, 2015, 'Endothelial BKCa, but not TRPV4 activity is altered in focal cerebral ischemic stroke', in Allen DG; Davey DF (eds.), Proceedings of the Australian Physiology Society, Australian Physiology Society, Hobart, pp. 59P - 59P, presented at Australian Physiology Society Meeting 2015, Hobart, 29 November - 02 December 2015, http://aups.org.au/Proceedings/46/59P/
Sandow SL; Hinkley V; Leader L; Grayson TH; Murphy TV, 2015, 'IKCa-IP3R myoendothelial microdomains in the uterine radial arteriole are present in normal, and absent in gestational and pre-eclamptic hypertensive pregnancies: Targets for therapy?', in Allen DG; Davey DF (eds.), Proceedings of the Australian Physiology Society, Australian Physiology Society, Hobart, pp. 122P - 122P, presented at Australian Physiology Society Conference 2015, Hobart, 29 November - 02 December 2015, http://aups.org.au/Proceedings/46/122P
Sandow SL; Jones NM; Nguyen HL; Grayson TH; Murphy TV, 2014, 'Acute hypoxia and focal cerebral ischemia result in endothelial BKCaα and β1 protein expression in intact adult rat middle cerebral artery endothelium', in Morris B (ed.), State of the Heart 2014, International Society of cardiovascular Pharmacotherapy, Adelaide, pp. 105 - 105, presented at Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy, Adelaide, 26 - 28 November 2014, http://www.hbprca.com.au/wp-content/uploads/SoTH_Workbook_FINAL_lowRes.pdf
Quek J; Boyd R; Ameer O; Murphy T; Phillips J, 2014, 'Altered structural and biomechanical properties of mesenteric resistance arteries in a rat model of cystic kidney disease', in JOURNAL OF VASCULAR RESEARCH, KARGER, Banff, CANADA, pp. 115 - 115, presented at 11th International Symposium on Resistance Arteries from Molecular Machinery to Clinical Challenges, Banff, CANADA, 07 - 11 September 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346236200097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Murphy T; Ivanov G; Senadheera S; Sandow S, 2014, 'Insulin increases IKCa expression and function in rat cremaster muscle arteries', in JOURNAL OF VASCULAR RESEARCH, KARGER, Banff, CANADA, pp. 37 - 37, presented at 11th International Symposium on Resistance Arteries from Molecular Machinery to Clinical Challenges, Banff, CANADA, 07 - 11 September 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346236200030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Sandow S; Jones NM; Nguyen HL; Grayson TH; Murphy T, 2014, 'Focal cerebral ischemia and acute hypoxia increase the expression of endothelial BKCa alpha and beta 1 protein in intact middle cerebral artery of the adult rat', in JOURNAL OF VASCULAR RESEARCH, KARGER, Banff, CANADA, pp. 122 - 122, presented at 11th International Symposium on Resistance Arteries from Molecular Machinery to Clinical Challenges, Banff, CANADA, 07 - 11 September 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346236200104&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Murphy TV; Kanagarajah A; Senadheera S; Sandow SL, 2013, 'TRPV4-mediated responses of the rat isolated cremaster muscle artery', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Boston, MA, presented at Joint Annual Meeting of the ASPET/BPS at Experimental Biology (EB), Boston, MA, 20 - 24 April 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000319860504432&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Senadheera S; Kim Y; Toemoe S; Bertrand P; Kochukov MY; Murphy TV; Marrelli SP; Tare M; Sandow SL, 2011, 'TRPC3 channels facilitate K-Ca-mediated endothelial vasodilator activity in rat mesenteric artery', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Washington, DC, presented at Experimental Biology Meeting 2011, Washington, DC, 09 - 13 April 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310708401110&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Howitt L; Sandow SL; Grayson TH; Morris MJ; Murphy TV, 2010, 'INCREASED NO-DEPENDENT DILATION OF RAT ARTERIOLES IN DIET-INDUCED OBESITY', in HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Sydney, AUSTRALIA, pp. 1499 - 1499, presented at 31st Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia, Sydney, AUSTRALIA, 01 - 03 December 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000277848100068&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Howitt L; Grayson TH; Morris MJ; Murphy TV, 2010, 'Increased NO-dependent dilation of rat arterioles in diet-induced obesity', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208675506830&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Murphy TV; Thiyagarajan L, 2009, 'INCREASED INTRA-LUMINAL PRESSURE ALTERS BETA-ADRENOCEPTOR SIGNALLING IN ISOLATED ARTERIOLES FROM THE RAT CREMASTER MUSCLE', in JOURNAL OF VASCULAR RESEARCH, KARGER, Queenstown, NEW ZEALAND, pp. 33 - 33, presented at 14th Meeting of the Australian-and-New-Zealand-Microcirculation-Society, Queenstown, NEW ZEALAND, 25 - 27 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000268340300034&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Yang Y; Ella SR; Murphy TV; Grayson TH; Hwang YT; Haddock R; Peichun G; Andrew BP; Korthuis RJ; Davis MJ, 2009, 'Relative lack of beta 1-subunit-mediated regulation of BKCa in cremaster arteriolar smooth muscle', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208621505276&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Howitt L; Grayson TH; Sandow SL; Morris MJ; Murphy TV, 2009, 'DIET-INDUCED OBESITY DOES NOT ALTER BKCa-MEDIATED RESPONSES IN RAT MID-CEREBRAL ARTERIOLES', in JOURNAL OF VASCULAR RESEARCH, KARGER, Queenstown, NEW ZEALAND, pp. 29 - 29, presented at 14th Meeting of the Australian-and-New-Zealand-Microcirculation-Society, Queenstown, NEW ZEALAND, 25 - 27 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000268340300030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Murphy TV; Ellis ZE; Howitt L; Morris MJ, 2008, 'EFFECT OF DIET-INDUCED OBESITY ON MYOGENIC RESPONSES OF ARTERIOLES FROM THE RAT CREMSTER MUSCLE', in HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Adelaide, AUSTRALIA, pp. 173 - 173, presented at 29th Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia, Adelaide, AUSTRALIA, 05 - 08 December 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000256880000070&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hill MA; Murphy TV; Sandow S; Triggle CR, 2006, 'The microvasculature as a therapeutic target in diabetes: Possible influence of vascular heterogeneity.', in ACTA PHARMACOLOGICA SINICA, BLACKWELL PUBLISHING, pp. 41 - 41, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000239590000238&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hill M; Sandow S; Ding H; Kotecha N; Murphy T, 2005, 'Endothelium-smooth muscle communication in arterioles: Effect of myogenic tone', in DRUG DEVELOPMENT RESEARCH, WILEY-LISS, Shanghai, PEOPLES R CHINA, pp. 219 - 220, presented at International Symposium on Cardiac Remodeling, Ion Channelpathy, Arrhythmias and Drug Discovery, Shanghai, PEOPLES R CHINA, 09 - 12 October 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000236442000016&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Presentations
Sandow SL; Nguyen HL; Ellinsworth DC; Grayson TH; Jones NM; Murphy TV, 2016, 'Increased BKCa and TRPV4 expression, and decreased caveolae density in distal middle cerebral artery endothelium and smooth muscle in focal cerebral ischemic stroke', Joint meeting of the Australian Vascular Biology and Atherosclerosis Societies and High Blood Pressure Research Council, Hobart, presented at Joint meeting of the Australian Vascular Biology and Atherosclerosis Societies and High Blood Pressure Research Council, Hobart, 07 - 10 December 2016
Sandow SL; Lucque N; Nguyen HL; Grayson TH; Russell FD; Hinkley V; Jones NM; Murphy TV, 2016, 'Ischemic stroke results in loss of cerebral artery endothelial and smooth muscle connexin (Cx) 37, and altered expression of Cx40, but not Cxs32 and 43', Joint meeting of the Australian Vascular Biology and Atherosclerosis Societies and High Blood Pressure Research Council, Hobart, presented at Joint meeting of the Australian Vascular Biology and Atherosclerosis Societies and High Blood Pressure Research Council, Hobart, 07 - 10 December 2016
Sandow SL; Jones NM; Nguyen HL; Ellinsworth D; Grayson TH; Grimley R; Dettrick A; Murphy TV, 2015, 'Focal cerebral ischemic stroke results in endothelial BKCa expression and altered function, with no change in TRPV4 function, in middle cerebral artery', Proceedings of the World Congress for Microcirculation, Kyoto, presented at Proceedings of the World Congress for Microcirculation, Kyoto, 25 - 27 September 2015
Sandow SL; Jones NM; Nguyen HL; Grayson TH; Murphy TV, 2014, 'Acute hypoxia and focal cerebral ischemia result in endothelial BKCaα and β1 protein expression in intact adult rat middle cerebral artery endothelium.', Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy, Adelaide, presented at Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy, Adelaide, 26 - 28 November 2014, http://www.hbprca.com.au/wp-content/uploads/SoTH_Workbook_FINAL_lowRes.pdf
Conference Abstracts
Murphy TV; Nguyen HL; Grayson TH; Jones NM; Sandow SL, 2016, 'Effect of focal cerebral ischemia on BKCa and TRPV4 in rat middle cerebral artery', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, Vol. 30, presented at Experimental Biology Meeting, San Diego, CA, 02 - 06 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406444706032&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Murphy TV; Kanagarajah A; Toemoe S; Bertrand PP; Grayson TH; Britton FC; Leader L; Senadheera S; Sandow SL, 2016, 'TRPV3 control of uterine blood vessels', in ASCEPT-MPGPCR Book of Oral Abstracts, ASCEPT ASM, Melbourne, Vol. 413, pp. 70 - 70, presented at Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists and Molecular Pharmacology of GPCRs Joint Scientific Meeting, Melbourne, 27 - 30 November 2016, http://www.asceptasm.com/wp-content/uploads/2016/11/ASCEPT-MPGPCR-Book-of-oral-abstracts-final-2.pdf
Phillips JK; Quek KJ; Boyd R; Ameer OZ; Murphy T, 2015, 'HIGH BLOOD PRESSURE AS A DRIVER OF STRUCTURAL AND BIOMECHANICAL CHANGES IN MESENTERIC RESISTANCE ARTERIES IN CHRONIC KIDNEY DISEASE', in HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Adelaide, AUSTRALIA, Vol. 65, pp. E39 - E40, presented at 36th Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia (HBPRCA), Adelaide, AUSTRALIA, 26 - 28 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352490400059&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
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