Dr Ria Arnold

Fields of research: Neurosciences, Neurology and Neuromuscular Diseases

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Ria Arnold is a Postdoctoral Fellow in the Department of Pharmacology, School of Medical Sciences, UNSW.

Ria is an Accredited Exercise Physiologist. Her research focuses on the neurological complications that occur in diabetes and chronic kidney disease. Her studies utilise neurophysiological techniques to investigate the mechanisms underlying nerve dysfunction and aim to develop physiological biomarkers for early detection of neuropathy in acquired metabolic diseases.

University role:

Lecturer

Research

Publications related to this Person

Book Chapters

Arnold R; Krishnan AV, 2014, 'Neuropathy and Other Neurological Problems in Chronic Kidney Disease', in Arici M (ed.), Management of Chronic Kidney Disease, Springer, pp. 343 - 352, http://dx.doi.org/10.1007/978-3-642-54637-2_26

Journal articles

Wild BM; Morris R; Moldovan M; Krarup C; Krishnan AV; Arnold R, 2018, 'In vivo electrophysiological measurement of the rat ulnar nerve with axonal excitability testing', Journal of Visualized Experiments, vol. 2018, http://dx.doi.org/10.3791/56102

Borire AA; Arnold R; Pussell BA; Kwai NC; Visser LH; Simon NG; Kiernan MC; Krishnan AV, 2018, 'Effects of hemodialysis on intraneural blood flow in end-stage kidney disease', Muscle and Nerve, vol. 57, pp. 287 - 293, http://dx.doi.org/10.1002/mus.25704

Arnold R; Pianta TJ; Pussell BA; Kirby A; O’Brien K; Sullivan K; Holyday M; Cormack C; Kiernan MC; Krishnan AV, 2017, 'Randomized, controlled trial of the effect of dietary potassium restriction on nerve function in CKD', Clinical Journal of the American Society of Nephrology, vol. 12, pp. 1569 - 1577, http://dx.doi.org/10.2215/CJN.00670117

Huynh W; Kwai N; Arnold R; Krishnan AV; Lin CSY; Vucic S; Kiernan MC, 2017, 'The effect of diabetes on cortical function in stroke: Implications for poststroke plasticity', Diabetes, vol. 66, pp. 1661 - 1670, http://dx.doi.org/10.2337/db16-0961

Borire AA; Arnold R; Pussell BA; Kwai NC; Visser LH; Padua L; Simon NG; Kiernan MC; Krishnan AV, 2017, 'Haemodialysis alters peripheral nerve morphology in end-stage kidney disease', Clinical Neurophysiology, vol. 128, pp. 281 - 286, http://dx.doi.org/10.1016/j.clinph.2016.09.010

Arnold R; Moldovan M; Rosberg MR; Krishnan AV; Morris R; Krarup C, 2017, 'Nerve excitability in the rat forelimb: a technique to improve translational utility', Journal of Neuroscience Methods, vol. 275, pp. 19 - 24, http://dx.doi.org/10.1016/j.jneumeth.2016.10.013

Arnold R; Issar T; Krishnan AV; Pussell BA, 2016, 'Neurological complications in chronic kidney disease.', JRSM Cardiovasc Dis, vol. 5, pp. 2048004016677687, http://dx.doi.org/10.1177/2048004016677687

Kwai NCG; Arnold R; Poynten AM; Krishnan AV, 2016, 'Association between glycemic variability and peripheral nerve dysfunction in type 1 diabetes', Muscle and Nerve, vol. 54, pp. 967 - 969, http://dx.doi.org/10.1002/mus.25274

Arnold R; Pussell BA; Kiernan MC; Krishnan AV, 2016, 'Comparative study to evaluate the effects of peritoneal and hemodialysis on peripheral nerve function', Muscle and Nerve, http://dx.doi.org/10.1002/mus.25016

Kwai NCG; Arnold R; Poynten AM; Howells J; Kiernan MC; Lin CS-Y; Krishnan AV, 2016, 'In vivo evidence of reduced nodal and paranodal conductances in type 1 diabetes', Clinical Neurophysiology, vol. 127, pp. 1700 - 1706, http://dx.doi.org/10.1016/j.clinph.2015.11.047

Arnold R; Huynh W; Kiernan MC; Krishnan AV, 2015, 'Ion channel modulation as a therapeutic approach in multiple sclerosis', Current Medicinal Chemistry, vol. 22, pp. 4366 - 4378, http://dx.doi.org/10.2174/0929867322666151029104452

Kwai N; Arnold R; Poynten AM; Lin CSY; Kiernan MC; Krishnan AV, 2015, 'Continuous subcutaneous insulin infusion preserves axonal function in type 1 diabetes mellitus', Diabetes/Metabolism Research and Reviews, vol. 31, pp. 175 - 182, http://dx.doi.org/10.1002/dmrr.2583

Arnold R; Kwai NCG; Krishnan AV, 2013, 'Mechanisms of axonal dysfunction in diabetic and uraemic neuropathies', Clinical Neurophysiology, vol. 124, pp. 2079 - 2090, http://dx.doi.org/10.1016/j.clinph.2013.04.012

Arnold R; Lin CS-Y; Krishnan AV; Pussell BA; Pianta TJ; Kiernan MC, 2013, 'Association Between Calcineurin Inhibitor Treatment and Peripheral Nerve Dysfunction in Renal Transplant Recipients', American Journal of Transplantation, http://dx.doi.org/10.1111/ajt.12324

Arnold R; Kwai N; Lin CSY; Poynten AM; Kiernan MC; Krishnan AV, 2013, 'Axonal dysfunction prior to neuropathy onset in type 1 diabetes', Diabetes/Metabolism Research and Reviews, vol. 29, pp. 53 - 59, http://dx.doi.org/10.1002/dmrr.2360

Arnold R; Pussell BA; Pianta TJ; Grinius V; Lin CSY; Kiernan MC; Howells J; Jardine MJ; Krishnan AV, 2013, 'Effects of Hemodiafiltration and High Flux Hemodialysis on Nerve Excitability in End-Stage Kidney Disease', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0059055

Kwai NCG; Arnold R; Wickremaarachchi C; Lin CSY; Poynten AM; Kiernan MC; Krishnan AV, 2013, 'Effects of axonal ion channel dysfunction on quality of life in type 2 diabetes', Diabetes Care, vol. 36, pp. 1272 - 1277, http://dx.doi.org/10.2337/dc12-1310

Arnold R; Lin CS-Y; Krishnan AV; Pussell BA; Grinius V; Howells J; Kiernan MC, 2013, 'Evidence for a causal relationship between hyperkalaemia and axonal dysfunction in end-stage kidney disease', Clinical Neurophysiology, http://dx.doi.org/10.1016/j.clinph.2013.06.022

Sung JY; Park SB; Liu YT; Kwai N; Arnold R; Krishnan AV; Lin CSY, 2012, 'Progressive axonal dysfunction precedes development of neuropathy in type 2 diabetes', Diabetes, vol. 61, pp. 1592 - 1598, http://dx.doi.org/10.2337/db11-1509

Sturnieks DL; Arnold R; Lord SR, 2011, 'Validity and reliability of the Swaymeter device for measuring postural sway', BMC Geriatrics, vol. 11, http://dx.doi.org/10.1186/1471-2318-11-63

Arnold R; Pianta T; Pussell B; Grinius V; Lin C; Kiernan M; Jardine M; Krishnan A, 2010, 'DIFFERENTIAL EFFECTS OF HAEMODIAFILTRATION ON HIGH FLUX HAEMODIALYSIS ON NERVE FUNCTION IN VITRO', NEPHROLOGY, vol. 15, pp. 86 - 86, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208652700227&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers

Arnold R; Pussell BA; Grinius V; Kiernan MC; Lin CS-Y; Krishnan AV, 2012, 'Evidence for a causal relationship between nerve dysfunction and hyperkalaemia in end-stage kidney disease', in Nephrology Dialysis Transplantation, 49th Congress of the European Renal Association/European Dialysis and Transplant Association, Paris, France, pp. ii70 - ii72, presented at 49th Congress of the European Renal Association/European Dialysis and Transplant Association, Paris, France, 25 - 27 May 2012, http://dx.doi.org/10.1093/ndt/gfs211

Kwai N; Arnold R; Wickremaarachchi, C; Poynten AM; Lin C; Kiernan MC; Krishnan A, 2011, 'Neurophysiological parameters and impaired quality of life in diabetic peripheral neuropathy', Australian Diabetes Society Scientific Meeting 2011, Perth, presented at Australian Diabetes Society Scientific Meeting 2011, Perth, 31 August 2011

Lin CS-Y; Sung JY; Park SB; Arnold R; Kwai N; Krishnan AV, 2011, 'Pre-diabetic neuropathy: Axonal dysfunction evident prior to clinical neuropathy', in Journal of the Peripheral Nervous System, Wiley, Potomac, Unites States of America, presented at Peripheral Nerve Society Meeting, Potomac, Unites States of America, 25 - 29 September 2011, http://dx.doi.org/10.1111/j.1529-8027.2011.00335.x

Arnold R; kwai N; Lin, C.S-Y; Kiernan, MC; Krishnan, AV, 2011, 'Evidence for distinct patterns of axonal excitability between type 1 and type 2 diabetic nerves', in Journal of the Peripheral Nervous System, Wiley, Potomac, Unites States of America, pp. S5 - S5, presented at Peripheral Nerve Society Meeting, Potomac, Unites States of America, 25 - 29 September 2011, http://dx.doi.org/10.1111/j.1529-8027.2011.00335.x

Arnold R; Lin CS-Y; Kiernan MC; Krishnan AV, 2011, 'W1.4 In vivo evidence of neurophysiological differentiation between type 1 and type 2 diabetic nerves', in Clinical Neurophysiology, European Congress of Clinical Neurophysiology, Rome, Italy, pp. S7 - S7, presented at European Congress of Clinical Neurophysiology, Rome, Italy, 21 - 25 June 2011, http://dx.doi.org/10.1016/S1388-2457(11)60021-7

Arnold R; Pianta T; Lin CS-Y; Pussell B; Grinius V; Kiernan MC; Jardine M; Krishnan AV, 2011, 'P4.17 Novel neurophysiological insights into uraemic neuropathy: implications for clinical trials', in Clinical Neurophysiology, European Congress of Clinical Neurophysiology, Rome, Italy, pp. S75 - S75, presented at European Congress of Clinical Neurophysiology, Rome, Italy, 21 - 25 June 2011, http://dx.doi.org/10.1016/S1388-2457(11)60256-3

Arnold R; Kwai N; Kiernan MC; Krishnan AV; Lin CS-Y, 2010, 'Differences in biophysical properties of axonal excitability in upper and lower limb sensory axons', in Journal of the Peripheral Nervous System, Wiley, Sydney, Australia, pp. 247 - 247, presented at Satellite Meeting of the Peripheral Nerve Society, Sydney, Australia, 05 - 07 July 2010, http://dx.doi.org/10.1111/j.1529-8027.2010.00277.x

Arnold R; Park SB; Kiernan MC; Krishnan AV; Lin CSY, 2010, 'P21-5 Sural nerve excitability: Implications for the early identification of peripheral nerve dysfunction', in Clinical Neurophysiology, International Congress of Clinical Neurophysiology, Kobe, Japan, pp. S227 - S227, presented at International Congress of Clinical Neurophysiology, Kobe, Japan, 28 October - 01 November 2010, http://dx.doi.org/10.1016/S1388-2457(10)60929-7

Conference Abstracts

Arnold R; Issar T; Kwai N; Pussell B; Poynten A; Krishnan A, 2018, 'Prevalence, impact and progression of peripheral neuropathy in early chronic kidney disease', in JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, WILEY, Baltimore, MD, Vol. 23, pp. 382 - 382, presented at Annual Meeting of the Peripheral-Nerve-Society, Baltimore, MD, 21 - 25 July 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000452787700327&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Borire NA; Arnold R; Krishnan A, 2016, 'Haemodialysis alters nerve morphology in chronic kidney disease', in Haemodialysis alters nerve morphology in chronic kidney disease, 16th Clinical Neurophysiology Workshop of the Australian and New Zealand Association of Neurologists, Sheraton Mirage Resort, Southport, Queensland, presented at 16th Clinical Neurophysiology Workshop of the Australian and New Zealand Association of Neurologists, Sheraton Mirage Resort, Southport, Queensland, 27 - 30 September 2015, http://dx.doi.org/10.1016/j.clinph.2015.11.034