Dr Ria Arnold

Fields of research: Neurosciences, Neurology and Neuromuscular Diseases, Nephrology and Urology, Endocrinology

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Dr Ria Arnold is an NHRMC Postdoctoral Research Fellow and Lecturer in the Department of Exercise Physiology, School of Health Sciences, UNSW. She is also an Accredited Exercise Physiologist.

Dr Arnold's research is focused on improving outcomes for people with peripheral neuropathy caused by diabetes and chronic kidney disease. Her studies span pathophysiological investigations, clinical trials, and health systems research. Her research program is also examining the role of Exercise Physiology as part of multidisciplinary care teams of dialysis and CKD patients. Her studies are working to identify pragmatic indicators for referral to exercise professionals and work toward equitable access to allied health in this context

University role:

Lecturer

Grants:

2018-21: Arnold, UNSW School of Medical Science Early Career Support Grant, UNSW $30,000

2016-18: Arnold, Rebecca Cooper Foundation Medical Research Grant $24,900

2015- 21: Arnold, NHMRC Early Career Fellowship $356,439

2014-14: Arnold, Boehringer Ingelheim Fonds Short Term Travel Fellowship $7,138

2012: Arnold, Pfizer Travel Sponsorship $5,000

2011 : Arnold, JDRF/Macquarie Foundation Early-Stage Scientist Research Travel Grant $4,000

Awards:

2020 Recipient of the UNSW School of Medical Science, Paper of the month October

2017 Recipient of the UNSW School of Medical Science, New Researcher of the Year Award

2015 Shortlisted for the Australian Diabetes Society Clinical Young Investigator Award at the Australian Diabetes Society Meeting, SA.

2014 Recipient of the UNSW Mark Rowe Prize - For outstanding doctoral thesis in Neurophysiology UNSW.

2013 Recipient of the UNSW Dean’s List Award - For Outstanding Research by PhD Candidate, Faculty of Medicine, UNSW.

2012 Recipient of the European Renal Association Young Investigator Award at the 49th Annual ERA Congress, Paris, France.

2011 Recipient of the Australian and New Zealand Association of Neurologists Best Free Communication Award the 14th Biennial Clinical Neurophysiology Workshop QLD.

2011 Recipient of the Tow Prize for Best Oral Communication at the Coast Medical Association/Combined Prince of Wales Campus Hospital. NSW.

2010 Recipient of the UWS Student Presentation Prize at the Australian Society for Medical Research Meeting, NSW.

2008 Recipient of the UNSW School of Medical Sciences Prize – For highest 4yr aggregate mark Health & Exercise Science, UNSW.

Keywords:

exercise physiology

peripheral neuropathy

kidney diseases

diabetes complications

Research

Teaching & Supervision

I am available to supervise:

Yes

Areas of supervision:

My area of specialty is neurological complications and physical limitations associated with metabolic diseases. This work helps identify the impact of neuromuscular on daily life and individuals' ability to engage with physical activity. This work also focuses on the improvement of health outcomes for individuals living with chronic and complex conditions and improving access to allied health services.

Currently supervising:

Peripheral Neuropathy in CKD: impact, screening and natural history

Examining the implications of self-reported physical limitation CKD;

Evaluating Outcomes of the Prince of Wales Healthy Aging Program (Community Exercise Program)

Teaching:

I convene the 3rd year Exercise Physiology Course HESC3592; Neuromuscular Rehabilitation

Media

Twitter Account:

https://twitter.com/DrRiaArnold

Publications related to this Person

Book Chapters

Arnold R; Krishnan AV, 2014, 'Neuropathy and Other Neurological Problems in Chronic Kidney Disease', in Arici M (ed.), Management of Chronic Kidney Disease, Springer, pp. 343 - 352, http://dx.doi.org/10.1007/978-3-642-54637-2_26

Journal articles

Issar T; Arnold R; Kwai NCG; Walker S; Yan A; Borire AA; Poynten AM; Pussell BA; Endre ZH; Kiernan MC; Krishnan AV, 2019, 'Relative contributions of diabetes and chronic kidney disease to neuropathy development in diabetic nephropathy patients', Clinical Neurophysiology, vol. 130, pp. 2088 - 2095, http://dx.doi.org/10.1016/j.clinph.2019.08.005

Deng F; Li Y; Hossain MJ; Kendig MD; Arnold R; Goldys EM; Morris MJ; Liu G, 2019, 'Polymer brush based fluorescent immunosensor for direct monitoring of interleukin-1β in rat blood', Analyst, vol. 144, pp. 5682 - 5690, http://dx.doi.org/10.1039/c9an01300h

Arnold R; Pianta TJ; Pussell BA; Endre Z; Kiernan MC; Krishnan AV, 2019, 'Potassium control in chronic kidney disease: implications for neuromuscular function', Internal Medicine Journal, vol. 49, pp. 817 - 825, http://dx.doi.org/10.1111/imj.14114

Issar T; Arnold R; Kwai NCG; Pussell BA; Endre ZH; Poynten AM; Kiernan MC; Krishnan AV, 2018, 'The utility of the Total Neuropathy Score as an instrument to assess neuropathy severity in chronic kidney disease: A validation study', Clinical Neurophysiology, vol. 129, pp. 889 - 894, http://dx.doi.org/10.1016/j.clinph.2018.02.120

Wild BM; Morris R; Moldovan M; Krarup C; Krishnan AV; Arnold R, 2018, 'In vivo electrophysiological measurement of the rat ulnar nerve with axonal excitability testing', Journal of Visualized Experiments, vol. 2018, http://dx.doi.org/10.3791/56102

Borire AA; Arnold R; Pussell BA; Kwai NC; Visser LH; Simon NG; Kiernan MC; Krishnan AV, 2018, 'Effects of hemodialysis on intraneural blood flow in end-stage kidney disease', Muscle and Nerve, vol. 57, pp. 287 - 293, http://dx.doi.org/10.1002/mus.25704

Arnold R; Pianta TJ; Pussell BA; Kirby A; O’Brien K; Sullivan K; Holyday M; Cormack C; Kiernan MC; Krishnan AV, 2017, 'Randomized, controlled trial of the effect of dietary potassium restriction on nerve function in CKD', Clinical Journal of the American Society of Nephrology, vol. 12, pp. 1569 - 1577, http://dx.doi.org/10.2215/CJN.00670117

Huynh W; Kwai N; Arnold R; Krishnan AV; Lin CSY; Vucic S; Kiernan MC, 2017, 'The effect of diabetes on cortical function in stroke: Implications for poststroke plasticity', Diabetes, vol. 66, pp. 1661 - 1670, http://dx.doi.org/10.2337/db16-0961

Arnold R; Moldovan M; Rosberg MR; Krishnan AV; Morris R; Krarup C, 2017, 'Nerve excitability in the rat forelimb: a technique to improve translational utility', Journal of Neuroscience Methods, vol. 275, pp. 19 - 24, http://dx.doi.org/10.1016/j.jneumeth.2016.10.013

Borire AA; Arnold R; Pussell BA; Kwai NC; Visser LH; Padua L; Simon NG; Kiernan MC; Krishnan AV, 2017, 'Haemodialysis alters peripheral nerve morphology in end-stage kidney disease', Clinical Neurophysiology, vol. 128, pp. 281 - 286, http://dx.doi.org/10.1016/j.clinph.2016.09.010

Arnold R; Issar T; Krishnan AV; Pussell BA, 2016, 'Neurological complications in chronic kidney disease', JRSM CARDIOVASCULAR DISEASE, vol. 5, http://dx.doi.org/10.1177/2048004016677687

Kwai NCG; Arnold R; Poynten AM; Krishnan AV, 2016, 'Association between glycemic variability and peripheral nerve dysfunction in type 1 diabetes', Muscle and Nerve, vol. 54, pp. 967 - 969, http://dx.doi.org/10.1002/mus.25274

Arnold R; Pussell BA; Kiernan MC; Krishnan AV, 2016, 'Comparative study to evaluate the effects of peritoneal and hemodialysis on peripheral nerve function', Muscle and Nerve, vol. 54, pp. 58 - 64, http://dx.doi.org/10.1002/mus.25016

Kwai NCG; Arnold R; Poynten AM; Howells J; Kiernan MC; Lin CSY; Krishnan AV, 2016, 'In vivo evidence of reduced nodal and paranodal conductances in type 1 diabetes', Clinical Neurophysiology, vol. 127, pp. 1700 - 1706, http://dx.doi.org/10.1016/j.clinph.2015.11.047

Arnold R; Huynh W; Kiernan MC; Krishnan AV, 2015, 'Ion channel modulation as a therapeutic approach in multiple sclerosis', Current Medicinal Chemistry, vol. 22, pp. 4366 - 4378, http://dx.doi.org/10.2174/0929867322666151029104452

Kwai N; Arnold R; Poynten AM; Lin CSY; Kiernan MC; Krishnan AV, 2015, 'Continuous subcutaneous insulin infusion preserves axonal function in type 1 diabetes mellitus', Diabetes/Metabolism Research and Reviews, vol. 31, pp. 175 - 182, http://dx.doi.org/10.1002/dmrr.2583

Arnold R; Pussell BA; Howells J; Grinius V; Kiernan MC; Lin CSY; Krishnan AV, 2014, 'Evidence for a causal relationship between hyperkalaemia and axonal dysfunction in end-stage kidney disease', Clinical Neurophysiology, vol. 125, pp. 179 - 185, http://dx.doi.org/10.1016/j.clinph.2013.06.022

Arnold R; Kwai NCG; Krishnan AV, 2013, 'Mechanisms of axonal dysfunction in diabetic and uraemic neuropathies', Clinical Neurophysiology, vol. 124, pp. 2079 - 2090, http://dx.doi.org/10.1016/j.clinph.2013.04.012

Arnold R; Pussell BA; Pianta TJ; Lin CSY; Kiernan MC; Krishnan AV, 2013, 'Association between calcineurin inhibitor treatment and peripheral nerve dysfunction in renal transplant recipients', American Journal of Transplantation, vol. 13, pp. 2426 - 2432, http://dx.doi.org/10.1111/ajt.12324

Kwai NCG; Arnold R; Wickremaarachchi C; Lin CS-Y; Poynten AM; Kiernan MC; Krishnan AV, 2013, 'Effects of Axonal Ion-Channel Dysfunction on Quality of Life in Type 2 Diabetes.', Diabetes Care, vol. 36, pp. 1272 - 1277, http://dx.doi.org/10.2337/dc12-1310

Arnold R; Pussell B; Pianta T; Grinius V; Lin CS-Y; Kiernan MC; Howells J; Jardine MJ; Krishnan AV, 2013, 'Effects of Hemodiafiltration and High Flux Hemodialysis on Nerve Excitability in End-Stage Kidney Disease', PLoS ONE, vol. 8, pp. Article number e59055, http://dx.doi.org/10.1371/journal.pone.0059055

Arnold R; Kwai NCG; Lin CS-Y; Poynten AM; Kiernan MC; Krishnan AV, 2013, 'Axonal dysfunction prior to neuropathy onset in type 1 diabetes', Diabetes - Metabolism Research and Reviews, vol. 29, pp. 53 - 59, http://dx.doi.org/10.1002/dmrr.2360

Sung J; Park SB; Liu Y; Kwai N; Arnold R; Krishnan AV; Lin CS-Y, 2012, 'Progressive axonal dysfunction precedes development of neuropathy in type 2 Diabetes.', Diabetes, vol. 61, pp. 1592 - 1598, http://dx.doi.org/10.2337/db11-1509

Sturnieks DL; Arnold R; Lord SR, 2011, 'Valididty and reliability of the swaymeter device for measuring postural sway', BMC Geriatrics, vol. 11, http://dx.doi.org/10.1186/1471-2318-11-63

Arnold R; Pianta T; Pussell B; Grinius V; Lin C; Kiernan M; Jardine M; Krishnan A, 2010, 'DIFFERENTIAL EFFECTS OF HAEMODIAFILTRATION ON HIGH FLUX HAEMODIALYSIS ON NERVE FUNCTION IN VITRO', NEPHROLOGY, vol. 15, pp. 86 - 86, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208652700227&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers

Arnold R; Kwai N; Poynten A; Lin CS-Y; Kiernan MC; Krishnan AV, 2011, 'Altered axonal excitability in asymptomatic type 1 diabetic patients', in Clinical Neurophysiology, ANZAN Clinical Neurophysiology Workshop, Gold Coast, Queensland, pp. e73 - e73, presented at ANZAN Clinical Neurophysiology Workshop, Gold Coast, Queensland, 02 October 2011 - 05 October 2011, http://dx.doi.org/10.1016/j.clinph.2011.11.023

Arnold R; kwai N ; Lin, C.S-Y ; Kiernan, MC ; Krishnan, AV , 2011, 'Evidence for distinct patterns of axonal excitability between type 1 and type 2 diabetic nerves', in Journal of the Peripheral Nervous System, Wiley, Potomac, Unites States of America, pp. S5 - S5, presented at Peripheral Nerve Society Meeting, Potomac, Unites States of America, 25 September 2011 - 29 September 2011, http://dx.doi.org/10.1111/j.1529-8027.2011.00335.x

Lin CS-Y ; Sung JY ; Park SB ; Arnold R; Kwai N ; Krishnan AV , 2011, 'Pre-diabetic neuropathy: Axonal dysfunction evident prior to clinical neuropathy', in Journal of the Peripheral Nervous System, Wiley, Potomac, Unites States of America, presented at Peripheral Nerve Society Meeting, Potomac, Unites States of America, 25 September 2011 - 29 September 2011, http://dx.doi.org/10.1111/j.1529-8027.2011.00335.x

Kwai N; Arnold R; Wickremaarachchi, C; Poynten AM; Lin C; Kiernan MC; Krishnan A, 2011, 'Neurophysiological parameters and impaired quality of life in diabetic peripheral neuropathy', Perth, presented at Australian Diabetes Society Scientific Meeting 2011, Perth, 31 August 2011

Arnold R; Pianta T; Lin CS-Y; Pussell B; Grinius V; Kiernan MC; Jardine M; Krishnan AV, 2011, 'P4.17 Novel neurophysiological insights into uraemic neuropathy: implications for clinical trials', in Clinical Neurophysiology, European Congress of Clinical Neurophysiology, Rome, Italy, pp. S75 - S75, presented at European Congress of Clinical Neurophysiology, Rome, Italy, 21 June 2011 - 25 June 2011, http://dx.doi.org/10.1016/S1388-2457(11)60256-3

Arnold R; Lin CS-Y; Kiernan MC; Krishnan AV, 2011, 'W1.4 In vivo evidence of neurophysiological differentiation between type 1 and type 2 diabetic nerves', in Clinical Neurophysiology, European Congress of Clinical Neurophysiology, Rome, Italy, pp. S7 - S7, presented at European Congress of Clinical Neurophysiology, Rome, Italy, 21 June 2011 - 25 June 2011, http://dx.doi.org/10.1016/S1388-2457(11)60021-7

Arnold R; Park SB; Kiernan MC; Krishnan AV; Lin CSY, 2010, 'P21-5 Sural nerve excitability: Implications for the early identification of peripheral nerve dysfunction', in Clinical Neurophysiology, International Congress of Clinical Neurophysiology, Kobe, Japan, pp. S227 - S227, presented at International Congress of Clinical Neurophysiology, Kobe, Japan, 28 October 2010 - 01 November 2010, http://dx.doi.org/10.1016/S1388-2457(10)60929-7

Arnold R; Kwai N ; Kiernan MC ; Krishnan AV ; Lin CS-Y , 2010, 'Differences in biophysical properties of axonal excitability in upper and lower limb sensory axons', in Journal of the Peripheral Nervous System, Wiley, Sydney, Australia, pp. 247 - 247, presented at Satellite Meeting of the Peripheral Nerve Society, Sydney, Australia, 05 July 2010 - 07 July 2010, http://dx.doi.org/10.1111/j.1529-8027.2010.00277.x

Conference Abstracts

Hossain MJ; Kendig MD; Wild BM; Morris MJ; Arnold R, 2021, 'Effects of Diet Reversal on Metabolic and Peripheral Neuropathy Endpoints in a Rat Model of Cafeteria Diet-Induced Obesity', in METABOLISM-CLINICAL AND EXPERIMENTAL, W B SAUNDERS CO-ELSEVIER INC, Vol. 116, pp. 68 - 69, http://dx.doi.org/10.1016/j.metabol.2020.154638

Kang A; Arnold R; Gallagher M; Snelling P; Green J; Fernando M; Kiernan M; Hand S; Grimley K; Burman J; Heath A; Rogers K; Bhattacharya A; Smyth B; Bradbury T; Hawley C; Perkovic V; Krishnan AV; Jardine M, 2020, 'THE FILTRATION IN THE NEUROPATHY OF END-STAGE KIDNEY DISEASE (FINESSE) RANDOMISED CONTROLLED TRIAL', in NEPHROLOGY, WILEY, Vol. 25, pp. 11 - 11, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000592647200009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hossain MJ; Kendig MD; Wild BM; Morris MJ; Arnold R, 2020, 'Longitudinal Characterization of Peripheral Neuropathy in a Cafeteria Diet and Low-Dose Streptozotocin Rat Model of Type 2 Diabetes', in DIABETES, AMER DIABETES ASSOC, ELECTR NETWORK, Vol. 69, presented at 80th Scientific Sessions of the American-Diabetes-Association (ADA), ELECTR NETWORK, 12 June 2020 - 16 June 2020, http://dx.doi.org/10.2337/db20-530-P

Arnold R; Issar T; Kwai N; Pussell B; Poynten A; Krishnan A, 2018, 'Prevalence, impact and progression of peripheral neuropathy in early chronic kidney disease', in JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, WILEY, Baltimore, MD, Vol. 23, pp. 382 - 382, presented at Annual Meeting of the Peripheral-Nerve-Society, Baltimore, MD, 21 July 2018 - 25 July 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000452787700327&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Borire NA; Arnold R; Krishnan A, 2015, 'Haemodialysis alters nerve morphology in chronic kidney disease', in Haemodialysis alters nerve morphology in chronic kidney disease, 16th Clinical Neurophysiology Workshop of the Australian and New Zealand Association of Neurologists, Sheraton Mirage Resort, Southport, Queensland, presented at 16th Clinical Neurophysiology Workshop of the Australian and New Zealand Association of Neurologists, Sheraton Mirage Resort, Southport, Queensland, 27 September 2015 - 30 September 2015, http://dx.doi.org/10.1016/j.clinph.2015.11.034