Dr Lawrence Lee
Contact Details
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Publications related to this Person
Book Chapters
Lee LK, 2017, 'Structural analysis of the flagellar component proteins in solution by small angle X-ray scattering', in Methods in Molecular Biology, pp. 105 - 117, http://dx.doi.org/10.1007/978-1-4939-6927-2_8
Journal articles
Berengut JF; Wong CK; Berengut JC; Doye JPK; Ouldridge TE; Lee LK, 2020, 'Self-Limiting Polymerization of DNA Origami Subunits with Strain Accumulation', ACS Nano, vol. 14, pp. 17428 - 17441, http://dx.doi.org/10.1021/acsnano.0c07696
Berengut JF; Berengut JC; Doye JPK; Prešern D; Kawamoto A; Ruan J; Wainwright MJ; Lee LK, 2019, 'Design and synthesis of pleated DNA origami nanotubes with adjustable diameters', Nucleic Acids Research, vol. 47, pp. 11963 - 11975, http://dx.doi.org/10.1093/nar/gkz1056
Baker MAB; Nieves DJ; Hilzenrat G; Berengut JF; Gaus K; Lee LK, 2019, 'Stoichiometric quantification of spatially dense assemblies with qPAINT', Nanoscale, vol. 11, pp. 12460 - 12464, http://dx.doi.org/10.1039/c9nr00472f
Baker MAB; Tuckwell AJ; Berengut JF; Bath J; Benn F; Duff AP; Whitten AE; Dunn KE; Hynson RM; Turberfield AJ; Lee LK, 2018, 'Dimensions and Global Twist of Single-Layer DNA Origami Measured by Small-Angle X-ray Scattering', ACS Nano, vol. 12, pp. 5791 - 5799, http://dx.doi.org/10.1021/acsnano.8b01669
Liew CW; Hynson RM; Ganuelas LA; Shah-Mohammadi N; Duff AP; Kojima S; Homma M; Lee LK, 2018, 'Solution structure analysis of the periplasmic region of bacterial flagellar motor stators by small angle X-ray scattering', Biochemical and Biophysical Research Communications, vol. 495, pp. 1614 - 1619, http://dx.doi.org/10.1016/j.bbrc.2017.11.194
Rosholm KR; Baker MAB; Ridone P; Nakayama Y; Rohde PR; Cuello LG; Lee LK; Martinac B, 2017, 'Activation of the mechanosensitive ion channel MscL by mechanical stimulation of supported Droplet-Hydrogel bilayers', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/srep45180
Baker MAB; Hynson RMG; Ganuelas LA; Mohammadi NS; Liew CW; Rey AA; Duff AP; Whitten AE; Jeffries CM; Delalez NJ; Morimoto YV; Stock D; Armitage JP; Turberfield AJ; Namba K; Berry RM; Lee LK, 2016, 'Domain-swap polymerization drives the self-assembly of the bacterial flagellar motor', Nature Structural and Molecular Biology, vol. 23, pp. 197 - 203, http://dx.doi.org/10.1038/nsmb.3172
Al-Zyoud WA; Hynson RMG; Ganuelas LA; Coster ACF; Duff AP; Baker MAB; Stewart AG; Giannoulatou E; Ho JWK; Gaus K; Liu D; Lee LK; Böcking T, 2016, 'Binding of transcription factor GabR to DNA requires recognition of DNA shape at a location distinct from its cognate binding site', Nucleic Acids Research, vol. 44, pp. 1411 - 1420, http://dx.doi.org/10.1093/nar/gkv1466
Do Kwon Y; Pancera M; Acharya P; Georgiev IS; Crooks ET; Gorman J; Joyce MG; Guttman M; Ma X; Narpala S; Soto C; Terry DS; Yang Y; Zhou T; Ahlsen G; Bailer RT; Chambers M; Chuang GY; Doria-Rose NA; Druz A; Hallen MA; Harned A; Kirys T; Louder MK; O'Dell S; Ofek G; Osawa K; Prabhakaran M; Sastry M; Stewart-Jones GBE; Stuckey J; Thomas PV; Tittley T; Williams C; Zhang B; Zhao H; Zhou Z; Donald BR; Lee LK; Zolla-Pazner S; Baxa U; Schön A; Freire E; Shapiro L; Lee KK; Arthos J; Munro JB; Blanchard SC; Mothes W; Binley JM; McDermott AB; Mascola JR; Kwong PD, 2015, 'Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env', Nature Structural and Molecular Biology, vol. 22, pp. 522 - 531, http://dx.doi.org/10.1038/nsmb.3051
Hynson RMG; Duff AP; Kirby N; Mudie S; Lee LK, 2015, 'Differential ultracentrifugation coupled to small-angle X-ray scattering on macromolecular complexes', Journal of Applied Crystallography, vol. 48, pp. 769 - 775, http://dx.doi.org/10.1107/S1600576715005051
Lee HW; Lee HC; Lee LK; Teber ET; Bret Church W, 2014, 'The use of soluble protein structures in modeling helical proteins in a layered membrane', Journal of Biomolecular Structure and Dynamics, vol. 32, pp. 308 - 318, http://dx.doi.org/10.1080/07391102.2013.765808
Rath EM; Tessier D; Campbell AA; Lee HC; Werner T; Salam NK; Lee LK; Church WB, 2013, 'A benchmark server using high resolution protein structure data, and benchmark results for membrane helix predictions', BMC Bioinformatics, vol. 14, http://dx.doi.org/10.1186/1471-2105-14-111
Lee LK; Bryant KJ; Bouveret R; Lei P; Duff AP; Harrop SJ; Huang EP; Gelb M; Gray PP; Curmi PM; Cunningham AM; Church WB; Scott KF; Harvey R, 2013, 'Selective inhibition of human group IIA-secreted phospholipase a 2 (hGIIA) signaling reveals arachidonic acid metabolism is associated with colocalization of hGIIA to vimentin in rheumatoid synoviocytes', The Journal of Biological Chemistry, vol. 288, pp. 15269 - 15279, http://dx.doi.org/10.1074/jbc.M112.397893
Stewart A; Lee L; Donohoe M; Chaston J; Stock D, 2012, 'The dynamic stator stalk of rotary ATPases', PROTEIN SCIENCE, vol. 21, pp. 73 - 73, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000307019800060&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stock D; Namba K; Lee LK, 2012, 'Nanorotors and self-assembling macromolecular machines: The torque ring of the bacterial flagellar motor', Current Opinion in Biotechnology, vol. 23, pp. 545 - 554, http://dx.doi.org/10.1016/j.copbio.2012.01.008
Stewart AG; Lee LK; Donohoe M; Chaston JJ; Stock D, 2012, 'The dynamic stator stalk of rotary ATPases', Nature communications, vol. 3, http://dx.doi.org/10.1038/ncomms1693
Kwong YD; Finzi A; Wu X; Dogo-Isonagie C; Lee LK; Moore LR; Schmidt SD; Stuckey J; Yang Y; Zhou T; Zhu J; Vicic DA; Debnath AK; Shapiro L; Bewley CA; Mascola JR; Sodroski JG; Kwong P, 2012, 'Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops', Proceedings of the National Academy of Sciences of the United States of America, vol. 109, pp. 5663 - 5668, http://dx.doi.org/10.1073/pnas.1112391109
Bryant KJ; Bidgood MJ; Lei P; Taberner ML; Salom C; Kumar V; Lee LK; Church W; Courtenay BG; Smart BP; Gelb M; Cahill MA; Graham GG; McNeil HP; Scott KF, 2011, 'A bifunctional role for group IIA secreted phospolipase A2 in human rheumatoid fibroblast-like synoviocyte arachidonic acid metabolism', The Journal of Biological Chemistry, vol. 286, pp. 2492 - 2503, http://dx.doi.org/10.1074/jbc.M110.123927
Lee LK; Ginsburg M; Crovace C; Donohoe M; Stock D, 2010, 'Structure of the torque ring of the flagellar motor and the molecular basis for rotational switching', Nature, vol. 466, pp. 996 - 1000, http://dx.doi.org/10.1038/nature09300
Lee LK; Stewart AG; Donohoe M; Bernal RA; Stock D, 2010, 'The Structure of the peripheral stalk of Thermus thermophilus H+-ATPase/Synthase', Nature Structural and Molecular Biology, vol. 17, pp. 373 - 378, http://dx.doi.org/10.1038/nsmb.1761
Scott KF; Lei P-W; Lee LK; Bidgood MJ; Taberner M; Salom C; Courtenay BG; Bryant KJ; Church WB; Graham GG; McNeill HP, 2005, 'Regulation of intracellular prostaglandin biosynthetic pathways by "outside-in" secreted phospholipase A(2)-dependent signalling in fibroblast-like synoviocytes', INFLAMMATION RESEARCH, vol. 54, pp. S182 - S182, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000205501600313&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Papers
Hertel S; Liew CW; Baker MA; Lee LK, 2017, 'Artificial assembly of the bacterial flagella motor protein FliG on DNA nanostructures', in EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, SPRINGER, British Biophys Soc, Edinburgh, SCOTLAND, pp. S345 - S345, presented at 19th IUPAB Congress / 11th EBSA Congress, British Biophys Soc, Edinburgh, SCOTLAND, 16 July 2017 - 20 July 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000416406202012&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Baker MA; Tuckwell AJ; Berengut JF; Bath J; Benn F; Duff AP; Whitten AE; Dunn KE; Hynson RM; Turberfield AJ; Lee LK, 2017, 'DNA origami dimensions and structure measured by solution X-ray scattering', in EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, SPRINGER, British Biophys Soc, Edinburgh, SCOTLAND, pp. S137 - S137, presented at 19th IUPAB Congress / 11th EBSA Congress, British Biophys Soc, Edinburgh, SCOTLAND, 16 July 2017 - 20 July 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000416406200296&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stock D; Lee LK, 2011, 'Molecular basis for rotational switching in the bacterial flagellar motor', in ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, INT UNION CRYSTALLOGRAPHY, pp. C36 - C36, http://dx.doi.org/10.1107/S0108767311099211
Wong KR; Shui WM; Graham SL; Lee LK; Church W, 2009, 'Integrating, Managing and Analyzing Protein Structures with XML Databases', in 8th Internaltional Conference on Database Systems for Advanced Applications ( DASFAA 2003), Brisbane, Australia, pp. 319 - 326, presented at 14th International Conference on Database Systems for Advanced Applications, Brisbane, Australia, 20 April 2009 - 23 April 2009, http://dx.doi.org/10.1109/DASFAA.2003.1192397
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