
Dr Justine Stehn
Fields of research: Cancer Cell Biology, Molecular Targets, Cell Development, Proliferation and Death, Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics)
Contact Details
Phone: +61 2 9385 8591
Email: j.stehn@unsw.edu.au
Supervision
- PHD
- Masters
- Honours
Tabs
Publications related to this Person
Book Chapters
Bonello T; Coombes J; Schevzov G; Gunning P; Stehn J, 2012, 'Therapeutic Targeting of the Actin Cytoskeleton in Cancer', in Kavallaris M (ed.), Cytoskeleton and Human Disease, pp. 181 - 200, http://dx.doi.org/10.1007/978-1-61779-788-0_10
Journal articles
Wang Y; Stear JH; Swain A; Xu X; Bryce NS; Carnell M; Alieva IB; Dugina VB; Cripe TP; Stehn J; Hardeman EC; Gunning PW, 2020, 'Drug Targeting the Actin Cytoskeleton Potentiates the Cytotoxicity of Low Dose Vincristine by Abrogating Actin-Mediated Repair of Spindle Defects', Molecular cancer research : MCR, vol. 18, pp. 1074 - 1087, http://dx.doi.org/10.1158/1541-7786.MCR-19-1122
Bryce NS; Failes TW; Stehn JR; Baker K; Zahler S; Arzhaeva Y; Bischof L; Lyons C; Dedova I; Arndt GM; Gaus K; Goult BT; Hardeman EC; Gunning PW; Lock JG, 2019, 'High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained', Cell Systems, vol. 9, pp. 496 - 507.e5, http://dx.doi.org/10.1016/j.cels.2019.09.002
Kee AJ; Chagan J; Chan JY; Bryce NS; Lucas CA; Zeng J; Hook J; Treutlein H; Laybutt DR; Stehn JR; Gunning PW; Hardeman EC, 2018, 'On-target action of anti-tropomyosin drugs regulates glucose metabolism', Scientific Reports, vol. 8, http://dx.doi.org/10.1038/s41598-018-22946-x
Mitchell CB; Stehn JR; O'Neill GM, 2018, 'Small molecule targeting of the actin associating protein tropomyosin Tpm3.1 increases neuroblastoma cell response to inhibition of Rac-mediated multicellular invasion', Cytoskeleton, vol. 75, pp. 307 - 317, http://dx.doi.org/10.1002/cm.21452
Currier MA; Stehn JR; Swain A; Chen D; Hook J; Eiffe E; Heaton A; Brown D; Nartker BA; Eaves DW; Kloss N; Treutlein H; Zeng J; Alieva IB; Dugina VB; Hardeman EC; Gunning PW; Cripe TP, 2017, 'Identification of cancer-targeted tropomyosin inhibitors and their synergy with microtubule drugs', Molecular Cancer Therapeutics, vol. 16, pp. 1555 - 1565, http://dx.doi.org/10.1158/1535-7163.MCT-16-0873
Desouza-Armstrong M; Gunning PW; Stehn JR, 2017, 'Tumor suppressor tropomyosin Tpm2.1 regulates sensitivity to apoptosis beyond anoikis characterized by changes in the levels of intrinsic apoptosis proteins', Cytoskeleton, vol. 74, pp. 233 - 248, http://dx.doi.org/10.1002/cm.21367
Bonello TT; Janco M; Hook J; Byun A; Appaduray M; Dedova I; Hitchcock-DeGregori S; Hardeman EC; Stehn JR; Böcking T; Gunning PW, 2016, 'A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep19816
Glass JJ; Phillips PA; Gunning PW; Stehn JR, 2015, 'Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells', BMC Cancer, vol. 15, http://dx.doi.org/10.1186/s12885-015-1741-8
Jalilian I; Heu C; Cheng H; Freittag H; Desouza M; Stehn JR; Bryce NS; Whan RM; Hardeman EC; Fath T; Schevzov G; Gunning PW, 2015, 'Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0126214
Schevzov G; Kee AJ; Wang B; Sequeira VB; Hook J; Coombes JD; Lucas CA; Stehn JR; Musgrove EA; Cretu A; Assoian R; Fath T; Hanoch T; Seger R; Pleines I; Kile BT; Hardeman EC; Gunning PW, 2015, 'Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments', Molecular Biology of the Cell, vol. 26, pp. 2475 - 2490, http://dx.doi.org/10.1091/mbc.E14-10-1453
Bryce NS; De Laurentiis A; Failes T; Arndt GM; Stehn JR; Hardeman EC; Gunning PW, 2015, 'Identification of the possible states of organisation of the actin cytoskeleton using high content image screening of a high diversity chemical library.', MOLECULAR BIOLOGY OF THE CELL, vol. 26, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209928400229&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stehn JR; Chen D; Currier MA; Eaves D; Desouza M; Moosavian M; Cripe TP; Gunning PW, 2014, 'Synergistic anti-neuroblastoma efficacy using combinatorial cytoskeletal inhibitors', CANCER RESEARCH, vol. 74, http://dx.doi.org/10.1158/1538-7445.PEDCAN-B50
Vindin H; Bischof L; Gunning P; Stehn J, 2014, 'Validation of an algorithm to quantify changes in actin cytoskeletal organization', Journal of Biomolecular Screening, vol. 19, pp. 354 - 368, http://dx.doi.org/10.1177/1087057113503494
Desouza M; Nguyen M; Gunning PW; Stehn JR, 2013, 'Targeting the actin cytoskeleton of neuroblastoma: Elucidating the mechanism by which a novel class of anti-cancer compounds induces tumor cell death.', MOLECULAR CANCER THERAPEUTICS, vol. 12, http://dx.doi.org/10.1158/1535-7163.TARG-13-C208
Wang B; Schevzov G; Coombes J; Hook J; Kee A; Lucas C; Stehn J; Sequeira V; Seger R; Hardeman E; Gunning P, 2013, 'Regulation of cell proliferation mediated by the actin filament regulator Tropomyosin 5NM1', MOLECULAR BIOLOGY OF THE CELL, vol. 24, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348702025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stehn JR; Haass NK; Bonello T; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PR; Sequeira VB; Butler TL; Allanson M; Fath T; Hill TA; McCluskey A; Schevzov G; Palmer S; Hardeman EC; Winlaw D; Reeve VE; Dixon I; Weninger W; Cripe TP; Gunning PW, 2013, 'A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells', Cancer research, vol. 73, pp. 5169 - 5182, http://dx.doi.org/10.1158/0008-5472.CAN-12-4501
Schevzov G; Coombes J; Hook J; Wang B; Kee A; Lucas C; Szokolai R; Sequeira V; Stehn J; Musgrove E; Hardeman E; Gunning P, 2012, 'Regulation of cell proliferation mediated by the actin filament stabilizing protein, Tropomyosin 5NM1.', MOLECULAR BIOLOGY OF THE CELL, vol. 23, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348601219&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Desouza M; Gunning P; Stehn JR, 2012, 'The actin cytoskeleton as a sensor and mediator of apoptosis', BioArchitecture, vol. 23, pp. 75 - 87, http://dx.doi.org/10.4161/bioa.20975
Creed S; Desouza M; Bamburg J; Gunning P; Stehn J, 2011, 'Tropomyosin isoform 3 promotes the formation of filopodia by regulating the recruitment of actin-binding proteins to actin filaments', Experimental Cell Research, vol. 317, pp. 249 - 261, http://dx.doi.org/10.1016/j.yexcr.2010.10.019
Bonello T; Stehn J; Gunning P, 2009, 'New approaches to targeting the actin cytoskeleton for chemotherapy.', Future Medicinal Chemistry, vol. 1, pp. 1311 - 1331, http://dx.doi.org/10.4155/fmc.09.99
Bach CT; Creed S; Zhong J; Mahmassani M; Schevzov G; Stehn J; Cowell L; Naumanen P; Lappalainen P; Gunning P; O''neill G, 2009, 'Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction', Molecular and Cellular Biology, vol. 29, pp. 1506 - 1514, http://dx.doi.org/10.1128/MCB.00857-08
Creed SJ; Bryce N; Naumanen P; Weinberger R; Lappalainen P; Stehn J; Gunning P, 2008, 'Tropomyosin isoforms define distinct microfilament populations with different drug susceptibility', European Journal of Cell Biology, vol. 87, pp. 709 - 720, http://dx.doi.org/10.1016/j.ejcb.2008.03.004
O Neill GM; Stehn J; Gunning P, 2007, 'Tropomyosins as interpreters of the signalling environment to regulate the local cytoskeleton', Seminars in Cancer Biology, vol. 18, pp. 35 - 44, http://dx.doi.org/10.1016/j.semcancer.2007.08.004
Ludowyke RI; Elgund Z; Kranenburg T; Stehn J; Schmitz-Peiffer C; Hughes WE; Biden TJ, 2006, 'Phosphorylation of non-muscle myosin heavy chain IIA on serine-1917 is mediated by protein kinase CâII and coincides with the onset of stimulated degranulation of RBL-2H3 mast cells', Journal of Immunology, vol. 177, pp. 1492 - 1499
Stehn J; Schevzov G; O''neill G; Gunning P, 2006, 'Specialisation of the tropomyosin composition of actin filaments provides new potential targets for chemotherapy.', Current Cancer Drug Targets, vol. 6, pp. 245 - 256, http://dx.doi.org/10.2174/156800906776842948
Nguyen A; Rothman DM; Stehn J; Imperiali B; Yaffe MB, 2004, 'Caged phosphopeptides reveal a temporal role for 14-3-3 in G1 arrest and S-phase checkpoint function', Nature Biotechnology, vol. 22, pp. 993 - 1000, http://dx.doi.org/10.1038/nbt997
Vazquez ME; Nitz M; Stehn J; Yaffe MB; Imperiali B, 2003, 'Fluorescent caged phosphoserine peptides as probes to investigate phosphorylation-dependent protein associations', Journal of the American Chemical Society, vol. 125, pp. 10150 - 10151, http://dx.doi.org/10.1021/ja0351847
Johnson BA; Stehn JR; Yaffe MB; Keith Blackwell T, 2002, 'Cytoplasmic localization of tristetraprolin involves 14-3-3-dependent and -independent mechanisms', Journal of Biological Chemistry, vol. 277, pp. 18029 - 18036, http://dx.doi.org/10.1074/jbc.M110465200
Brunet A; Kanai F; Stehn J; Xu J; Sarbassova D; Frangioni JV; Dalal SN; Decaprio JA; Greenberg ME; Yaffe MB, 2002, '14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport', Journal of Cell Biology, vol. 156, pp. 817 - 828, http://dx.doi.org/10.1083/jcb.200112059
Mitchell CJ; Kelly MM; Blewitt M; Wilson JR; Biden TJ, 2001, 'Phospholipase c-gamma mediates the hydrolysis of phosphatidylinositol, but not of phosphatidylinositol 4,5-bisphospate, in carbamylcholine-stimulated islets of langerhans', The Journal of Biological Chemistry, vol. 276, pp. 19072 - 19077, http://dx.doi.org/10.1074/jbc.M101406200
Wilson JR; Ludowyke RI; Biden TJ, 2001, 'A redistribution of actin and myosin IIA accompanies Ca2+-dependent insulin secretion', FEBS Letters, vol. 492, pp. 101 - 106, http://dx.doi.org/10.1016/S0014-5793(01)02241-4
Iismaa TP; Kerr EA; Wilson JR; Carpenter L; Sims N; Biden TJ, 2000, 'Quantitative and functional characterization of muscarinic receptor subtypes in insulin-secreting cell lines and rat pancreatic islets', Diabetes, vol. 49, pp. 392 - 398, http://dx.doi.org/10.2337/diabetes.49.3.392
Wilson JR; Ludowyke RI; Biden TJ, 1999, 'Potential role of PKC-Mediated myosin II phosphorylation in insulin secretion.', MOLECULAR BIOLOGY OF THE CELL, vol. 10, pp. 32A - 32A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083673500183&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Wilson JR; Biden TJ; Ludowyke RI, 1999, 'Increases in phosphorylation of the myosin II heavy chain, but not regulatory light chains, correlate with insulin secretion in rat pancreatic islets and RINm5F cells', Diabetes, vol. 48, pp. 2383 - 2389, http://dx.doi.org/10.2337/diabetes.48.12.2383
Wilson JR; Ludowyke RI; Biden TJ, 1998, 'Nutrient stimulation results in a rapid CA2+-dependent threonine phosphorylation of myosin heavy chain in rat pancreatic islets and RINm5F cells', The Journal of Biological Chemistry, vol. 273, pp. 22729 - 22737, http://dx.doi.org/10.1074/jbc.273.35.22729
Edwards MR; Knodler LA; Wilson JR; Schofield PJ, 1993, 'The transport and metabolism of alanine by Giardia intestinalis', Molecular and Biochemical Parasitology, vol. 61, pp. 49 - 57, http://dx.doi.org/10.1016/0166-6851(93)90157-S
Schofield PJ; Edwards MR; Matthews J; Wilson JR, 1992, 'The pathway of arginine catabolism in Giardia intestinalis', Molecular and Biochemical Parasitology, vol. 51, pp. 29 - 36, http://dx.doi.org/10.1016/0166-6851(92)90197-R
Conference Papers
Stehn JR; Haass NK; Bonello T; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PR; Butler T; Allanson M; Fath T; Hill TA; McCluskey A; Schevzov G; Palmer S; Hardeman EC; Winlaw D; Reeve VE; Dixon I; Weninger W; Cripe TP; Gunning P, 2012, 'Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells', in EXPERIMENTAL DERMATOLOGY, WILEY-BLACKWELL, Marburg, GERMANY, pp. e43 - e43, presented at 39th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Marburg, GERMANY, 01 March 2012 - 03 March 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000300931700252&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Bonello TT; Stehn J; Hitchcock-DeGregori S; Dixon I; Gunning P, 2011, 'Optimising models to examine the specificity of anti-tropomyosin compounds for Tm5NM1', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Denver, CO, presented at Annual Meeting of the American-Society-for-Cell-Biology (ASCB), Denver, CO, 03 December 2011 - 07 December 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000305505500216&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stehn J; Schevzov G; Bonello T; McCluskey A; Haass N; Palmer S; Hardeman E; Allanson M; Reeve V; Gunning P, 2010, 'Tropomyosin Tm5NM1: A novel target for cancer therapy', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, Berlin, GERMANY, pp. 107 - 107, presented at 22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Berlin, GERMANY, 16 November 2010 - 19 November 2010, http://dx.doi.org/10.1016/S1359-6349(10)72041-3
Floyd SR; Stehn JR; Wilker E; Yaffe MB, 2006, 'Chk1 phosphorylates poly-A binding protein, triggering translocation to the nucleus', in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, ELSEVIER SCIENCE INC, Philadelphia, PA, pp. S574 - S575, presented at 48th Annual Meeting of the American-Society-for-Therapeutic-Radiology-and-Oncology (ASTRO), Philadelphia, PA, 05 November 2006 - 09 November 2006, http://dx.doi.org/10.1016/j.ijrobp.2006.07.1071
Mohammad D; Carrigan C; Nguyen A; Rothman DM; Manke IA; Stehn J; Lim D; Jouhin B; Tidor B; Imperiali B; Yaffe MB, 2005, 'Phosphoserine/threonine-binding domains as dynamic modulators of kinase-dependent protein-protein interactions', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, pp. A1689 - A1689, presented at Experimental Biology 2005 Meeting/35th International Congress of Physiological Sciences, San Diego, CA, 31 March 2005 - 06 April 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000227610904661&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stehn JR; Yaffe MB, 2002, 'A high-throughput proteomics approach to identifying cell cycle checkpoint pathways regulated by DNA damage kinases and 14-3-3 proteins', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, SAN FRANCISCO, CALIFORNIA, pp. 417A - 418A, presented at 42nd Annual Meeting of the American-Society-for-Cell-Biology, SAN FRANCISCO, CALIFORNIA, 14 December 2002 - 18 December 2002, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000179569102349&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Wilson JR; Ludowyke RI; Biden JT, 1998, 'Potential role of myosin heavy chain phosphorylation in Ca2+-dependent insulin secretion', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, pp. 145A - 145A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000076906700842&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Presentations
Jalilian I; Schevzov G; Fath T; Heu C; Bischof L; Vindin H; Stehn JR; Tate MK; Hardeman EC; Gunning PW, 2014, 'Determining the impact of the actin cytoskeleton on the mechanical properties of cells.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094100060&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Stehn J; Chen D; Currier M; Eaves D; Desouza M; Cripe T; Gunning PW, 2014, 'Synergistic anti-cancer cell impact of anti-tropomyosin compounds with anti-microtubule drugs.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094104104&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Jalilian I; Schevzov G; Fath T; Heu C; Bischof L; Vindin H; Stehn JR; Tate MK; Hardeman EC; Gunning PW, 2014, 'Determining the impact of the actin cytoskeleton on the mechanical properties of cells', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 December 2014 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094106265&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Abstracts
Wang Y; Swain A; Stear JH; Bryce NS; Dugina VB; Alieva IB; Cripe TP; Stehn JR; Hardeman EC; Gunning PW, 2017, 'Synergy between anti-tropomyosin and anti-microtubule drugs reveals an interaction between actin and microtubule networks.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 28, presented at Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO), Philadelphia, PA, 02 December 2017 - 06 December 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426664301293&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Rynkiewicz M; Stehn J; Gunning P; Lehman W, 2014, 'Structure of the Anti-Cancer Compound TR100 Target-Sites on Tpm3.1 Tropomyosin', in BIOPHYSICAL JOURNAL, CELL PRESS, San Francisco, CA, Vol. 112, pp. 560A - 560A, presented at 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, 15 February 2014 - 19 February 2014, http://dx.doi.org/10.1016/j.bpj.2016.11.3019
Segueira VB; Stehn JR; Haass N; Bonello T; Guven K; Desouza M; Schevzov G; Kottyan G; McCluskey A; Bischof L; Palmer S; Hardeman EC; Allanson M; Reeve V; Weninger W; Cripe TP; Gunning P, 2012, 'Improving the specificity of drugs which target the actin cytoskeleton for cancer therapy', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-5230
Stehn JR; Haass NK; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PR; Han MH; Hill TA; McCluskey A; Palmer S; Hardeman EC; Weninger W; Cripe TR; Gunning P, 2012, 'Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1827
Patents
Gunning P; Stehn J; McCluskey A; Butler T; Dixon I, 2007, Compounds for treating Cancer, Australia, Patent No. Australian Provisional Patent Application No 2007906570, Patent Agent:
Gunning P; Stehn J; Schevzov G, 2005, Identification of compounds for the treatment of proliferative disorders, Australia, Patent No. Australian Provisional Patent Application No 2004906888, Patent Agent:
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