Associate Professor John Hunt
Fields of research: Humoral Immunology and Immunochemistry
Contact Details
Phone: +61 2 9385 1580
Fax: 51389
Email: j.hunt@unsw.edu.au
Tabs
Publications related to this Person
Book Chapters
Hunt JE; Stevens RL, 1996, 'Mouse mast cell proteases', in Biological and Molecular aspects of Mast Cell and Basophil, Differentiation and Function, edn. Original, Raven Press, New York, USA, pp. 149 - 160
Hunt J; Krilis, 1994, 'Immunology of Antiphospholipid Antibodies', in Panayi GS (ed.), Immunology of the Connective Tissue Diseases, Kluwer Academic Pub
Journal articles
Ai SSY; Hsu K; Herbert C; Cheng Z; Hunt J; Lewis CR; Thomas PS, 2013, 'Response to MtDNA depletions and deletions may also important in pathogenesis of lung cancer', Respiratory Medicine, vol. 107, pp. 1815, http://dx.doi.org/10.1016/j.rmed.2013.08.017
Yang Ai SS; Hsu K; Herbert C; Cheng Z; Hunt J; Lewis CR; Thomas PS, 2013, 'Mitochondrial DNA mutations in exhaled breath condensate of patients with lung cancer', Respiratory Medicine, vol. 107, pp. 911 - 918, http://dx.doi.org/10.1016/j.rmed.2013.02.007
Hunt JE; Scicluna H; McNeil HP, 2011, 'Development and evaluation of a mandatory research experience in an undergraduate medical education program: the independent learning project at UNSW.', Journal of the International Association of Medical Science Educators, vol. 21(1S), pp. 78 - 85, http://www.iamse.org/artman/publish/cat_index_94.shtml
Jackson NE; Wang H-W; Bryant KJ; McNeil HP; Husain A; Liu K; Tedla N; Thomas PS; King GC; Hettiaratchi A, 2008, 'Alternate mRNA Splicing in Multiple Human Tryptase Genes Is Predicted to Regulate Tetramer Formation', Journal of Biological Chemistry, vol. 283, pp. 34178 - 34187, http://dx.doi.org/10.1074/jbc.M807553200
Huynh OA; Hampartzoumian T; Arm JP; Hunt J; Borges L; Ahern M; Smith M; Geczy CL; McNeil HP; Tedla N, 2007, 'Down-regulation of leucocyte immunoglobulin-like receptor expression in the synovium of rheumatoid arthritis patients after treatment with disease-modifying anti-rheumatic drugs', Rheumatology, vol. 46, pp. 742 - 751, http://dx.doi.org/10.1093/rheumatology/kel405
Yang Z; Yan WX; Cai H; Tedla N; Armishaw C; Di Girolamo N; Wang HW; Hampartzoumian T; Simpson JL; Gibson PG, 2007, 'S100A12 provokes mast cell activation: A potential amplification pathway in asthma and innate immunity', Journal of Allergy and Clinical Immunology, vol. 119, pp. 106 - 114, http://dx.doi.org/10.1016/j.jaci.2006.08.021
Hettiaratchi A; Hawkins NJ; McKenzie G; Ward RL; Hunt JE; Wakefield D; Di Girolamo N, 2007, 'The collagenase-1 (MMP-1) gene promoter polymorphism - 1607/2G is associated with favourable prognosis in patients with colorectal cancer', British Journal of Cancer, vol. 96, pp. 783 - 792, http://dx.doi.org/10.1038/sj.bjc.6603630
Geczy CL; Yang Z; Yan W-X; Cai H; Tedla N; Perry M; Hunt J; Hart P, 2005, 'S100A12 and mast cell activation in inflammation', INFLAMMATION RESEARCH, vol. 54, pp. S129 - S129, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000205501600134&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Wei XM; Kim HS; Kumar RK; Heywood GJ; Hunt JE; McNeil HP; Thomas PS, 2005, 'Effects of cigarette smoke on degranulation and NO production by mast cells and epithelial cells', RESPIRATORY RESEARCH, vol. 6, http://dx.doi.org/10.1186/1465-9921-6-108
Jackson NE; Wang H-W; Tedla N; McNeil HP; Geczy CL; Collins A; Grimm MC; Hampartzoumian T; Hunt JE, 2005, 'IL-15 induces mast cell migration via a pertussis toxin-sensitive receptor', European Journal of Immunology, vol. 35, pp. 2376 - 2385, http://dx.doi.org/10.1002/eji.200526154
Wang H-W; Tedla N; Hunt JE; Wakefield D; McNeil HP, 2005, 'Mast cell accumulation and cytokine expression in the tight skin mouse model of scleroderma', Experimental Dermatology, vol. 14, pp. 295 - 302, http://dx.doi.org/10.1111/j.0906-6705.2005.00315.x
Li M; Liu K; Michalicek J; Angus JA; Hunt JE; Dell'Italia LJ; Feneley MP; Graham RM; Husain A, 2004, 'Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.', J Clin Invest, vol. 114, pp. 112 - 120, http://dx.doi.org/10.1172/JCI20805
Wang H-W; McNeil HP; Husain A; Liu K; Tedla N; Thomas PS; Raftery M; King GC; Cai ZY; Hunt JE, 2002, 'Delta tryptase is expressed in multiple human tissues, and a recombinant form has proteolytic activity.', J Immunol, vol. 169, pp. 5145 - 5152, https://www.ncbi.nlm.nih.gov/pubmed/12391231
Friend DS; Gurish MF; Austen KF; Hunt J; Stevens RL, 2000, 'Senescent jejunal mast cells and eosinophils in the mouse preferentially translocate to the spleen and draining lymph node, respectively, during the recovery phase of helminth infection.', J Immunol, vol. 165, pp. 344 - 352, https://www.ncbi.nlm.nih.gov/pubmed/10861071
Huang C; Li L; Krilis SA; Chanasyk K; Tang Y; Li Z; Hunt JE; Stevens RL, 1999, 'Human Tryptases α and β/II Are Functionally Distinct Due, in Part, to a Single Amino Acid Difference in One of the Surface Loops That Forms the Substrate-binding Cleft', Journal of Biological Chemistry, vol. 274, pp. 19670 - 19676, http://dx.doi.org/10.1074/jbc.274.28.19670
Friend DS; Gurish MF; Hunt J; Hu X; Austen KF; Stevens RL, 1998, 'Fate of jejunal mast cells in mice infected with trichinella spiralis', FASEB Journal, vol. 12
Friend DS; Ghildyal N; Gurish MF; Hunt J; Hu XZ; Austen KF; Stevens RL, 1998, 'Reversible expression of tryptases and chymases in the jejunal mast cells of mice infected with Trichinella spiralis', JOURNAL OF IMMUNOLOGY, vol. 160, pp. 5537 - 5545, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000073735400045&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Huang C; Friend DS; Qiu WT; Wong GW; Morales G; Hunt J; Stevens RL, 1998, 'Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6.', J Immunol, vol. 160, pp. 1910 - 1919, https://www.ncbi.nlm.nih.gov/pubmed/9469453
Hunt JE; Friend DS; Gurish MF; Feyfant E; Šali A; Huang C; Ghildyal N; Stechschulte S; Austen KF; Stevens RL, 1997, 'Mouse Mast Cell Protease 9, a Novel Member of the Chromosome 14 Family of Serine Proteases that is Selectively Expressed in Uterine Mast Cells', Journal of Biological Chemistry, vol. 272, pp. 29158 - 29166, http://dx.doi.org/10.1074/jbc.272.46.29158
Stevens RL; Oui D; McNeil HP; Friend DS; Hunt JE; Austen KF; Zhang J, 1996, 'Transgenic mice that possess a disrupted mast cell protease 5 (MMCP-5) gene can not store carboxypeptidase a (MMC-CPA) protein in their granules', FASEB Journal, vol. 10
Hunt JE; Stevens RL; Austen KF; Zhang J; Xia Z; Ghildyal N, 1996, 'Natural Disruption of the Mouse Mast Cell Protease 7 Gene in the C57BL/6 Mouse', Journal of Biological Chemistry, vol. 271, pp. 2851 - 2855, http://dx.doi.org/10.1074/jbc.271.5.2851
Bingham CO; Murakami M; Fujishima H; Hunt JE; Austen KF; Arm JP, 1996, 'A Heparin-sensitive Phospholipase A 2 and Prostaglandin Endoperoxide Synthase-2 Are Functionally Linked in the Delayed Phase of Prostaglandin D 2 Generation in Mouse Bone Marrow-derived Mast Cells', Journal of Biological Chemistry, vol. 271, pp. 25936 - 25944, http://dx.doi.org/10.1074/jbc.271.42.25936
Kandiah DA; Hunt JE; Krilis SA, 1995, 'Epitope mapping studies of antiphospholipid antibodies and β
Kandiah DA; Hunt JE; Krilis SA, 1995, 'Epitope mapping studies of antiphospholipid antibodies and β2-GPI using synthetic peptides', Lupus, vol. 4, pp. S7 - S11, http://dx.doi.org/10.1177/096120339400400103
Stevens JM; Hunt JE; Seymour AE; Krilis SA; Pugsley DJ, 1994, 'Sneddon's syndrome, anti-cardiolipin antibody and glomerular thrombosis', Clinical Nephrology, vol. 41, pp. 18 - 22
Hunt J; Krilis S, 1994, 'The fifth domain of β
Hunt JE; Adelstein S; Krilis SA, 1994, 'New basic aspects of the antiphospholipid syndrome', Clinical and Experimental Rheumatology, vol. 12, pp. 661 - 668
Hunt JE; Krilis SA, 1993, 'Antiphospholipid antibodies, beta 2-glycoprotein I and thrombosis.', Lupus, vol. 2, pp. 285 - 287, http://dx.doi.org/10.1177/096120339300200501
Vlachoyiannopoulos PG; Beigbeder G; Dueymes M; Youinou P; Hunt JE; Krilis SA; Moutsopoulos HM, 1993, 'Antibodies to Phosphatidylethanolamine in Antiphospholipid Syndrome and Systemic Lupus Erythematosus: Their Correlation with Anticardiolipin Antibodies and P 2 Glycoprotein-I Plasma Levels', Autoimmunity, vol. 16, pp. 245 - 249, http://dx.doi.org/10.3109/08916939309014642
Hunt JE; Simpson RJ; Krilis SA, 1993, 'Identification of a region of β2-glycoprotein I critical for lipid binding and anti-cardiolipin antibody cofactor activity', Proceedings of the National Academy of Sciences of the United States of America, vol. 90, pp. 2141 - 2145, http://dx.doi.org/10.1073/pnas.90.6.2141
VLACHOYIANNOPOULOS PG; KRILIS SA; HUNT JE; MANOUSSAKIS MN; MOUTSOPOULOS HM, 1992, 'Patients with anticardiolipin antibodies with and without antiphospholipid syndrome: their clinical features and β 2 -glycoprotein-l plasma levels', European Journal of Clinical Investigation, vol. 22, pp. 482 - 487, http://dx.doi.org/10.1111/j.1365-2362.1992.tb01494.x
McNeil HP; Hunt JE; KRILIST SA, 1992, 'Antiphospholipid Antibodies–New Insights into their Specificity and Clinical Importance', Scandinavian Journal of Immunology, vol. 36, pp. 647 - 650, http://dx.doi.org/10.1111/j.1365-3083.1992.tb03124.x
Hunt JE; McNeil HP; Morgan GJ; Crameri RM; Krilis SA, 1992, 'A phospholipid-beta 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection.', Lupus, vol. 1, pp. 75 - 81, http://dx.doi.org/10.1177/096120339200100204
HUNT JE; MCNEIL HP; KRILIS SA, 1991, 'ANTICARDIOLIPIN ANTIBODIES FROM AUTOIMMUNE-DISEASE AND INFECTION HAVE DIFFERENT BINDING SPECIFICITIES', FASEB JOURNAL, vol. 5, pp. A1088 - A1088, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1991FC55000993&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Ang C; Clark E; Young I; Owe-Young R; Eyland A; Hunt J; Chesterman C; Krilis S, 1990, '15-Hydroxyeicosatetraenoic acid synthesis from exogenous arachidonate by bronchial mucosa', Journal of Lipid Mediators, vol. 2, pp. 263 - 269
McNeil HP; Hunt JE; Krilis SA, 1990, 'New aspects of anticardiolipin antibodies', Clinical and Experimental Rheumatology, vol. 8, pp. 525 - 527
Conference Papers
Wang HW; Tedia N; Hunt JE; Wakefield D; McNeill HP, 2000, 'Mechanisms of mast cell accumulation in tight skin (Tsk) mouse model of scleroderma', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, pp. A1151 - A1151, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000086643101404&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Conference Presentations
Ai S; Cheng Z; Hunt J; Lewis C; Hsu K; Herbert C; Thomas PS, 2011, 'MITOCHONDRIAL DNA MUTATIONS IN THE EXHALED BREATH CONDENSATE OF PATIENTS WITH LUNG CANCER', in JOURNAL OF THORACIC ONCOLOGY, ELSEVIER SCIENCE INC, Melbourne, AUSTRALIA, Vol. 6, pp. S34 - S35, presented at 3rd Australian Lung Cancer Conference (ALCC), Melbourne, AUSTRALIA, 07 - 09 October 2010, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000287990600127&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Hunt JE; Jackson N; Wang HW; Geczy C; Collins A; Hettiaratchi A; McNeil P, 2001, 'Murine bone-marrow derived mast cells migrate in response to IL-15', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 15, pp. A355 - A355, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000167438102030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Wang HW; McNeil HP; Thomas PS; Murphy B; Webster MJ; Hettiaratchi A; King G; Heywood G; Huang C; Hunt JE, 2000, 'Molecular cloning and characterisation of novel human tryptase cDNAs and splice variants', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 14, pp. A1239 - A1239, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000086643101924&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Hunt JE; Wang HW; Heywood G; McNeil HP, 1999, 'Mouse mast cell protease-G expression in uterine mast cells is upregulated in late pregnancy and post partum.', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 13, pp. A1132 - A1132, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000082132902796&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Chen J; Hunt JE; Morgner A; McNeil HP; Tedla N; Hampart-zoumian T; Wang HW; O'Rourke J; Collins A; Friend D, 1999, 'Induction of IL-15 and a novel mast cell phenotype in mice infected with Helicobacter felis', in GUT, BRITISH MED JOURNAL PUBL GROUP, Vol. 45, pp. A61 - A61, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000082469400197&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Hunt JE; Chen J; McNeil HP; Tedla N; Hampartzoumian T; Wang HW; O'Rourke J; Collins A; Friend D; Austen KF, 1999, 'Induction of IL-15 and a novel mouse mast cell phenotype in mice infected with Helicobacter felis.', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 13, pp. A291 - A291, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000082033301679&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Hunt J; Chen J; McNeil HP; Telda N; Hampartzoumiam T; Wang HW; O'Rourke JL; Morgner A; Collins A; Friend D, 1999, 'Induction of IL-15 and a novel mast cell phenotype in a mouse model of helicobacter infection.', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, Vol. 116, pp. A192 - A192, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000079778400839&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
KRILLIS SA; HUNT JE, 1993, 'EPITOPE MAPPING OF THE PHOSPHOLIPID AND ANTICARDIOLIPIN ANTIBODY-BINDING SITES ON BETA-2-GLYCOPROTEIN .1.', in ARTHRITIS AND RHEUMATISM, LIPPINCOTT-RAVEN PUBL, Vol. 36, pp. S75 - S75, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993MB81600220&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
HUNT J; KRILIS S, 1993, 'A PHOSPHOLIPID-BINDING SITE AND A REGION RECOGNIZED BY ANTICARDIOLIPIN ANTIBODIES IS LOCATED IN THE 5TH DOMAIN OF BETA-2-GLYCOPROTEIN-I', in JOURNAL OF LEUKOCYTE BIOLOGY, FEDERATION AMER SOC EXP BIOL, pp. 76 - 76, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993ME18500254&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
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