Associate Professor John Hunt
Fields of research: Humoral Immunology and Immunochemistry
Contact Details
Phone: +61 2 9385 1580
Fax: 51389
Email: j.hunt@unsw.edu.au
Tabs
Publications related to this Person
Book Chapters
Hunt JE; Stevens RL, 1996, 'Mouse mast cell proteases', in Biological and Molecular aspects of Mast Cell and Basophil, Differentiation and Function, edn. Original, Raven Press, New York, USA, pp. 149 - 160
Hunt J; Krilis , 1994, 'Immunology of Antiphospholipid Antibodies', in Panayi GS (ed.), Immunology of the Connective Tissue Diseases, Kluwer Academic Pub
Journal articles
Yang Ai SS; Hsu K; Herbert C; Cheng Z; Hunt J; Lewis CR; Thomas PS, 2013, 'Mitochondrial DNA mutations in exhaled breath condensate of patients with lung cancer', Respir Med, vol. 107, pp. 911 - 918, http://dx.doi.org/10.1016/j.rmed.2013.02.007
Yang Ai SS; Hsu K; Herbert C; Cheng Z; Hunt J; Lewis CR; Thomas PS, 2013, 'Response to “MtDNA depletions and deletions may also important in pathogenesis of lung cancer”', Respiratory Medicine, vol. 107, pp. 1815 - 1815, http://dx.doi.org/10.1016/j.rmed.2013.08.017
Hunt JE; Scicluna H; McNeil HP, 2011, 'Development and evaluation of a mandatory research experience in an undergraduate medical education program: the independent learning project at UNSW.', Journal of the International Association of Medical Science Educators, vol. 21(1S), pp. 78 - 85, http://www.iamse.org/artman/publish/cat_index_94.shtml
Jackson NE; Wang H; Bryant KJ; McNeil HP; Husain A; Liu K; Tedla NT; Thomas PS; King GC; Hettiaratchi A; Cairns J; Hunt JE, 2008, 'Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation.', The Journal of Biological Chemistry, vol. 283, pp. 34178 - 34187, http://dx.doi.org/10.1074/jbc.M807553200
Hettiaratchi A; Hawkins NJ; McKenzie GL; Ward RL; Hunt JE; Wakefield D; Di Girolamo N, 2007, 'The collagenase-1 (MMP-1) gene promoter polymorphism - 1607/2G is associated with favourable prognosis in patients with colorectal cancer', British Journal of Cancer, vol. 96, pp. 783 - 792, http://dx.doi.org/10.1038/sj.bjc.6603630
Yang Z; Yan WX; Cai H; Tedla NT; Armishaw C; Di Girolamo N; Wang H; Hampartzoumian T; Simpson J; Gibson P; Hunt JE; Hart P; Hughes J; Perry MA; Alewood P; Geczy C, 2007, 'S100A12 provokes mast cell activation: A potential amplification pathway in asthma and innate immunity', Journal of Allergy and Clinical Immunology, vol. 119, pp. 106 - 114, http://dx.doi.org/10.1016/j.jaci.2006.08.021
Huynh OA; Hampartzoumian T; Arm JP; Hunt JE; Borges L; Ahern MJ; Smith MD; Geczy C; McNeil HP; Tedla NT, 2007, 'Down-regulation of leucocyte immunoglobulin-like receptor expression in the synovium of rheumatoid arthritis patients after treatment with disease-modifying anti-rheumatic drugs', Rheumatology, vol. 46, pp. 742 - 751, http://dx.doi.org/10.1093/rheumatology/kel405
Geczy CL; Yang Z; Yan W-X; Cai H; Tedla N; Perry M; Hunt J; Hart P, 2005, 'S100A12 and mast cell activation in inflammation', INFLAMMATION RESEARCH, vol. 54, pp. S129 - S129, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000205501600134&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Wei XM; Kim HS; Kumar RK; Heywood GJ; Hunt JE; McNeil HP; Thomas PS, 2005, 'Effects of cigarette smoke on degranulation and NO production by mast cells and epithelial cells', Respiratory Research, vol. 6, http://dx.doi.org/10.1186/1465-9921-6-108
Jackson NE; Tedla NT; Geczy C; Collins AM; Grimm M; Hampartzoumian T; Hunt JE; Wang H; McNeil HP, 2005, 'IL-15 induces mast cell migration via a pertussis toxin-sensitive receptor', European Journal of Immunology, vol. 35, pp. 2376 - 2385, http://dx.doi.org/10.1002/eji.200526154
Wang H; Tedla NT; Hunt JE; Wakefield D; McNeil HP, 2005, 'Mast cell accumulation and cytokine expression in the tight skin mouse model of scleroderma', Experimental Dermatology, vol. 14, pp. 295 - 302, http://dx.doi.org/10.1111/j.0906-6705.2005.00315.x
Li M; Michalicek J; Angus JA; Hunt JE; Dell Italia L; Feneley MP; Graham RM; Husain A, 2004, 'Involvement of chymase-mediated angiotensin II generation in blood pressure regulation', Journal of Clinical Investigation, vol. 114, pp. 112 - 120, http://dx.doi.org/10.1172/JCI200420805
King GC; Wang H; Mcneil PM; Husain A; Liu KH; Tedla NT; Thomas PS; Raftery MJ; Hunt JE, 2002, 'Delta tryptase Is Expressed in Multiple Human Tissues, and a Recombinant Form has Proteolytic Activity', Immunology, vol. 169, pp. 5145 - 5152
Friend DS; Gurish MF; Austen KF; Hunt JE; Stevens RL, 2000, 'Senescent jejunal mast cells and eosinophils in the mouse preferentially translocate to the spleen and draining lymph node, respectively, during the recovery phase of helminth infection', Journal of Immunology, vol. 165, pp. 344 - 352, http://dx.doi.org/10.4049/jimmunol.165.1.344
Huang C; Li L; Krilis S; Chanasyk K; Tang Y; Li Z; Hunt JE; Stevens RL, 1999, 'Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft', The Journal of Biological Chemistry, vol. 274, pp. 19670 - 19676, http://dx.doi.org/10.1074/jbc.274.28.19670
Friend DS; Gurish MF; Hunt J; Hu X; Austen KF; Stevens RL, 1998, 'Fate of jejunal mast cells in mice infected with trichinella spiralis', FASEB Journal, vol. 12
Huang C; Friend DS; Qiu D; Wong GW; Morales G; Hunt JE; Stevens RL, 1998, 'Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by the tryptase mouse mast cell protease 6.', Journal of Immunology, vol. 160, pp. 1910 - 1919, https://www.ncbi.nlm.nih.gov/pubmed/9469453
Friend DS; Ghildyal N; Gurish MF; Hunt JE; Hu X; Austen KF; Stevens RL, 1998, 'Reversible expression of tryptases and chymases in thejejunal mast cells of mice infected with trichinella spiralis.', Journal of Immunology, vol. 160, pp. 5537 - 5545, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000073735400045&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Hunt JE; Friend DS; Gurish MF; Feyfant E; Sali A; Huang C; Ghildyal N; Stechshulte S; Austen KF; Stevens RL, 1997, 'Mouse mast cell protease 9, a novel member of the chromosome 14 family of serine proteases that is selectively expressed in uterine mast cells', The Journal of Biological Chemistry, vol. 272, pp. 29158 - 29166, http://dx.doi.org/10.1074/jbc.272.46.29158
Stevens RL; Oui D; McNeil HP; Friend DS; Hunt JE; Austen KF; Zhang J, 1996, 'Transgenic mice that possess a disrupted mast cell protease 5 (MMCP-5) gene can not store carboxypeptidase a (MMC-CPA) protein in their granules', FASEB Journal, vol. 10
Hunt JE; Stevens RL; Austen KF; Zhang J; Xia Z; Ghildyal N, 1996, 'Natural disruption of the mouse mast cell protease (mMCP)-7 gene in the C57BL/6 mouse', The Journal of Biological Chemistry, vol. 271, pp. 2851 - 2855, http://dx.doi.org/10.1074/jbc.271.5.2851
Bingham CO; Murakami M; Fujishima H; Hunt JE; Austen KF; Arm JA, 1996, 'A Heparin-sensitive phospholipase A2 and prostaglandin endoperoxidase synthase-1 are functionally linked in the delayed phase of prostoglandin D2 generation in mouse bone-marrow derived mast cells', The Journal of Biological Chemistry, vol. 271, pp. 25936 - 25944, http://dx.doi.org/10.1074/jbc.271.42.25936
Kandiah DA; Hunt JE; Krilis SA, 1995, 'Epitope mapping studies of antiphospholipid antibodies and β
Kandiah DA; Hunt JE; Krilis SA, 1995, 'Epitope mapping studies of antiphospholipid antibodies and β
Hunt JE; Adelstein S; Krilis SA, 1994, 'New basic aspects of the antiphospholipid syndrome', Clinical and Experimental Rheumatology, vol. 12, pp. 661 - 668
Hunt J; Krilis S, 1994, 'The fifth domain of β
Stevens JM; Hunt JE; Seymour AE; Krilis SA; Pugsley DJ, 1994, 'Sneddon's syndrome, anti-cardiolipin antibody and glomerular thrombosis', Clinical Nephrology, vol. 41, pp. 18 - 22
Vlachoyiannopoulos PG; Beigbeder G; Dueymes M; Youinou P; Hunt JE; Krilis SA; Moutsopoulos HM, 1993, 'Antibodies to phosphatidylethanolamine in antiphospholipid syndrome and systemic lupus erythematosus: Their correlation with anticardiolipin antibodies and p
Hunt JE; Krilis SA, 1993, 'Antiphosphotipid Antibodies, β2-Glycoprotein I and Thrombosis', Lupus, vol. 2, pp. 285 - 287, http://dx.doi.org/10.1177/096120339300200501
Hunt JE; Simpson RJ; Krilis SA, 1993, 'Identification of a region of β2-glycoprotein I critical for lipid binding and anti-cardiolipin antibody cofactor activity', Proceedings of the National Academy of Sciences of the United States of America, vol. 90, pp. 2141 - 2145, http://dx.doi.org/10.1073/pnas.90.6.2141
Hunt JE; McNeil HP; Morgan GJ; Crameri RM; Krilis SA, 1992, 'A phospholipid-beta 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection.', Lupus, vol. 1, pp. 75 - 81, http://dx.doi.org/10.1177/096120339200100204
McNeil HP; Hunt JE; KRILIST SA, 1992, 'Antiphospholipid Antibodies–New Insights into their Specificity and Clinical Importance', Scandinavian Journal of Immunology, vol. 36, pp. 647 - 650, http://dx.doi.org/10.1111/j.1365-3083.1992.tb03124.x
VLACHOYIANNOPOULOS PG; KRILIS SA; HUNT JE; MANOUSSAKIS MN; MOUTSOPOULOS HM, 1992, 'Patients with anticardiolipin antibodies with and without antiphospholipid syndrome: their clinical features and β
HUNT JE; MCNEIL HP; KRILIS SA, 1991, 'ANTICARDIOLIPIN ANTIBODIES FROM AUTOIMMUNE-DISEASE AND INFECTION HAVE DIFFERENT BINDING SPECIFICITIES', FASEB JOURNAL, vol. 5, pp. A1088 - A1088, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1991FC55000993&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
McNeil HP; Hunt JE; Krilis SA, 1990, 'New aspects of anticardiolipin antibodies', Clinical and Experimental Rheumatology, vol. 8, pp. 525 - 527
Ang C; Clark E; Young. I; Owe-Young R; Eyland A; Hunt J; Chesterman. C; Krilis. S, 1990, '15-Hydroxyeicosatetraenoic acid synthesis from exogenous arachidonate by bronchial mucosa', Journal of Lipid Mediators, vol. 2, pp. 263 - 269
Conference Papers
Wang HW; Tedia N; Hunt JE; Wakefield D; McNeill HP, 2000, 'Mechanisms of mast cell accumulation in tight skin (Tsk) mouse model of scleroderma', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, pp. A1151 - A1151, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000086643101404&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Presentations
Ai S; Cheng Z; Hunt J; Lewis C; Hsu K; Herbert C; Thomas PS, 2010, 'MITOCHONDRIAL DNA MUTATIONS IN THE EXHALED BREATH CONDENSATE OF PATIENTS WITH LUNG CANCER', in JOURNAL OF THORACIC ONCOLOGY, ELSEVIER SCIENCE INC, Melbourne, AUSTRALIA, Vol. 6, pp. S34 - S35, presented at 3rd Australian Lung Cancer Conference (ALCC), Melbourne, AUSTRALIA, 07 October 2010 - 09 October 2010, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000287990600127&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hunt JE; Jackson N; Wang HW; Geczy C; Collins A; Hettiaratchi A; McNeil P, 2001, 'Murine bone-marrow derived mast cells migrate in response to IL-15', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 15, pp. A355 - A355, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000167438102030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Wang HW; McNeil HP; Thomas PS; Murphy B; Webster MJ; Hettiaratchi A; King G; Heywood G; Huang C; Hunt JE, 2000, 'Molecular cloning and characterisation of novel human tryptase cDNAs and splice variants', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 14, pp. A1239 - A1239, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000086643101924&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Chen J; Hunt JE; Morgner A; McNeil HP; Tedla N; Hampart-zoumian T; Wang HW; O'Rourke J; Collins A; Friend D; Austen KF; Lee A, 1999, 'Induction of IL-15 and a novel mast cell phenotype in mice infected with Helicobacter felis', in GUT, BRITISH MED JOURNAL PUBL GROUP, Vol. 45, pp. A61 - A61, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000082469400197&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hunt J; Chen J; McNeil HP; Telda N; Hampartzoumiam T; Wang HW; O'Rourke JL; Morgner A; Collins A; Friend D; Austen KF; Lee A, 1999, 'Induction of IL-15 and a novel mast cell phenotype in a mouse model of helicobacter infection.', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, Vol. 116, pp. A192 - A192, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000079778400839&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hunt JE; Wang HW; Heywood G; McNeil HP, 1999, 'Mouse mast cell protease-G expression in uterine mast cells is upregulated in late pregnancy and post partum.', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 13, pp. A1132 - A1132, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000082132902796&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Hunt JE; Chen J; McNeil HP; Tedla N; Hampartzoumian T; Wang HW; O'Rourke J; Collins A; Friend D; Austen KF; Lee A, 1999, 'Induction of IL-15 and a novel mouse mast cell phenotype in mice infected with Helicobacter felis.', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 13, pp. A291 - A291, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000082033301679&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
KRILLIS SA; HUNT JE, 1993, 'EPITOPE MAPPING OF THE PHOSPHOLIPID AND ANTICARDIOLIPIN ANTIBODY-BINDING SITES ON BETA-2-GLYCOPROTEIN .1.', in ARTHRITIS AND RHEUMATISM, LIPPINCOTT-RAVEN PUBL, Vol. 36, pp. S75 - S75, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993MB81600220&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
HUNT J; KRILIS S, 1993, 'A PHOSPHOLIPID-BINDING SITE AND A REGION RECOGNIZED BY ANTICARDIOLIPIN ANTIBODIES IS LOCATED IN THE 5TH DOMAIN OF BETA-2-GLYCOPROTEIN-I', in JOURNAL OF LEUKOCYTE BIOLOGY, FEDERATION AMER SOC EXP BIOL, pp. 76 - 76, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993ME18500254&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
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