Associate Professor David Simar

Fields of research: Cancer and related disorders, Metabolic Medicine, Cellular Immunology, Exercise Physiology, Paediatrics

Contact Details

Phone: +61 2 9385 8142
Fax: 51389
Email: d.simar@unsw.edu.au

Supervision

PHD
Masters
Honours

Tabs

Main

Research Group:
Immunometabolism Research Group (Head)

Mechanisms of Disease and Translational Research

School of Medical Sciences

Research Interests:
My research interest mainly focuses on the characterisation of metabolic dysfunction and the critical role played by the immune system in the development of those alterations in metabolic and immune conditions.

Broad Research Areas:
Metabolism, Inflammation, Immunology, Cancer, Diabetes, Exercise Physiology

Qualifications:
BSc, PhD (Montpellier)

Specific Research Keywords:
Cell Metabolism, Insulin resistance, Immunology and Infectious Disease, Cancer, Exercise Physiology

Projects on offer (suitable for Honours, Masters and PhD):
The role of epigenetic modifications in long-term memory of irradiation in cancer survivors

Metabolic complications in cancer survivors

Physical activity in cancer survivors

University role:

Director of Postgraduate Research UNSW Medicine

Grants:

2018-19: Goldstein D, Park S, McCrary MJ, Menant J, Harris C, Simar D.Exercise rehabilitation for cancer survivors with chemotherapy-induced peripheral neuropathy: Impact and mechanisms.Cancer Clinical Academic Group seed grant scheme, AU$200,000.

2014: Zekry A, Simar D, Lloyd A.T-cell metabolic pathways as a predictor of anti-HCV T-cell immune response and outcomes after primary HCV infection.Australian Centre for HIV and Hepatitis Virology Research, AU$ 95,000.

2013-15: Hardeman E, Barres R, Simar D, Cohn R. The role of epigenetic modifications in longterm memory of irradiation in cancer survivors. Cancer Council New South Wales, AU$ 360,000.

2010: Cohn R, Simar D.Metabolic complications in childhood leukaemia survivors. Cancer Institute New South Wales, AU$ 46,000.

2009: Chen H, Morris MJ, Simar D. Activation of brain glucose sensing mTOR pathway to improve glucose tolerance and reduce adiposity in offspring from obese dams.DARTResearchGrant, AU$ 59,400.

2008: Simar D. Impaired metabolism in peripheral blood mononuclear cells condition the antiviral response in hepatitis C virus infection,Faculty of Medicine: UNSW Sydney, AU$ 11,800.

2008: Chen H, Morris MJ, Simar D. Impact of maternal smoking and high fat diet feeding on pathways involved in central and peripheral glucose metabolism. DART Research Grant, AU$ 50,000.

2008-12: Fiatarone Singh M, Blair S, Singh N, O’Sullivan A, Simar D, Baune B. A randomised controlled trial of progressive resistance training in older type 2 diabetics at cardiovascular risk.NHMRC Research Grant, AU$ 806,250.

2008:Fiatarone Singh M, Blair S, Singh N, O’Sullivan A, Simar D, Baune B. Australian Diabetes Society – Servier National Diabetes Strategy Grant, AU$ 19,532.

2008: Simar D, Tzar C, Tejani N, Metabolic alterations in Polycistic Ovary Syndrome: protective effect of resistance training,Faculty of Medicine,UNSW Sydney:Early Career Research Grant, AU$ 30,000.

2008:Ruell P, Caillaud C, Thompson M, Simar D. Can plasma HSP70 be used to screen athletes at risk of injury from heatstroke?New South Wales Government, Research and Injury Prevention Scheme, AU$ 19,600.

2007:Caillaud C, Thompson M, Simar D, Kazlauskas R, Trout G, Howe C. Does exercise in hot environmental condition impair detection of EPO doping?Australian Government, Department of Communication, Information, Technology and the Arts, AU$ 125,358.

2007: Simar D, A new model to study insulin-stimulated glucose transport in type 2 diabetes,Faculty of Medicine,UNSW Sydney: Early Career Research Grant, AU$ 36,000.

Awards:

2015: Nordea-Fonden’s Residence Program at Heerings Gaard, Denmark.

2015: Quality and Innovation Award in Preventive Health, The Sydney Children’s Hospital Network.

2008: School of Medical Sciences, Faculty of Medicine, UNSW Sydney. New Researcher of the year

Keywords:

Cancer Survivorship

immunology

inflammation

endocrinology & metabolism

exercise physiology

child health

Groups:

Immunometabolism Research Group

Research

Research activities:

My research program investigates and targets the mechanisms responsible for long-term complications in cancer survivors, using a translational approach ranging from cellular models to animal and human studies.

Socio-economic Objective (SEO) tags:

Cancer and Related Disorders

Diabetes

Immune System and Allergy

Teaching & Supervision

I am available to supervise:

Yes

Areas of supervision:

I supervise ILP, honours, Masters and PhD students on the following projects:

- Metabolic complications in cancer survivors

- Physical activity in cancer survivors

Currently supervising:

PhD: Investigating the role of physical activity on functional, cardiovascular & psychological outcomes in childhood cancer: from diagnosis and in survivorship

PhD: Optimal dose exercise for reduction in inlfammatory activity in cancer patients

PhD: The impact of whole body irradiation on metabolism and skeletal muscle

Supervision keywords:

cancer

endocrinology & metabolism

inflammation

exercise physiology

child health

Teaching:

As a member of the Department of Exercise Physiology in the School of Medical Sciences, I convene the third year course Clinical Exercise Physiology offered to 3rd year students enrolled in the Program of Exercise Physiology. This course focuses on the epidemiology and the pathophysiology of respiratory, metabolic, cardiovascular and immune diseases. It develops knowledge of how to set up and implement exercise testing and programming in these special populations in order to provide symptomatic relief, as well as to manage the underlying disease.

Media

LinkedIn:

https://www.linkedin.com/profile/view?id=254603902&trk=nav_responsive_tab_profile

Publications related to this Person

Book Chapters

Simar D; Caillaud C, 2014, 'Antioxidant Supplementation in the Elderly and Leukocytes', in Aging: Oxidative Stress and Dietary Antioxidants, pp. 277 - 287, http://dx.doi.org/10.1016/B978-0-12-405933-7.00026-3

Simar D; Malatesta D; Caillaud C, 2010, 'Ageing', in Connes P; Hue O; Perrey S (ed.), EXERCISE PHYSIOLOGY: FROM A CELLULAR TO AN INTEGRATIVE APPROACH, edn. Biomedical and Health Research, IOS PRESS, pp. 654 - 670, http://dx.doi.org/10.3233/978-1-60750-497-9-654

Caillaud C; Simar D, 2004, 'Aptitude physique aerobie et age', in Jeandel C; Bernard PL; Seynnes O (ed.), Aptitude physique, sante et vieillissement, edn. 1st, Sauramps Medical, Montpellier, France, pp. 57 - 63

Simar D; Malatesta D, 2004, 'Mesure de l'aptitude physique aerobie chez les sujets ages', in Seynnes O; Jeandel C; Bernard PL (ed.), Aptitude physique, sante et vieillissement, edn. 1st, Sauramps Medical, Montpellier, France, pp. 65 - 71

Journal articles

Fabre O; Ingerslev LR; Garde C; Donkin I; Simar D; Barrès R, 2018, 'Exercise training alters the genomic response to acute exercise in human adipose tissue.', Epigenomics, vol. 10, pp. 1033 - 1050, http://dx.doi.org/10.2217/epi-2018-0039

Clifford BK; Mizrahi D; Sandler CX; Barry BK; Simar D; Wakefield CE; Goldstein D, 2018, 'Barriers and facilitators of exercise experienced by cancer survivors: a mixed methods systematic review.', Support Care Cancer, vol. 26, pp. 685 - 700, http://dx.doi.org/10.1007/s00520-017-3964-5

Mizrahi D; Wakefield CE; Fardell JE; Quinn VF; Lim Q; Clifford BK; Simar D; Ness KK; Cohn RJ, 2017, 'Distance-delivered physical activity interventions for childhood cancer survivors: A systematic review and meta-analysis.', Crit Rev Oncol Hematol, vol. 118, pp. 27 - 41, http://dx.doi.org/10.1016/j.critrevonc.2017.08.008

Palmer CS; Duette GA; Wagner MCE; Henstridge DC; Saleh S; Pereira C; Zhou J; Simar D; Lewin SR; Ostrowski M, 2017, 'Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection.', FEBS Lett, vol. 591, pp. 3319 - 3332, http://dx.doi.org/10.1002/1873-3468.12843

Luo A; Leach ST; Barres R; Hesson LB; Grimm MC; Simar D, 2017, 'The Microbiota and Epigenetic Regulation of T Helper 17/Regulatory T Cells: In Search of a Balanced Immune System.', Front Immunol, vol. 8, pp. 417, http://dx.doi.org/10.3389/fimmu.2017.00417

Nylander V; Ingerslev LR; Andersen E; Fabre O; Garde C; Rasmussen M; Citirikkaya K; Bæk J; Christensen GL; Aznar M, 2016, 'Ionizing Radiation Potentiates High-Fat Diet-Induced Insulin Resistance and Reprograms Skeletal Muscle and Adipose Progenitor Cells.', Diabetes, vol. 65, pp. 3573 - 3584, http://dx.doi.org/10.2337/db16-0364

Raghuraman S; Donkin I; Versteyhe S; Barrès R; Simar D, 2016, 'The Emerging Role of Epigenetics in Inflammation and Immunometabolism.', Trends Endocrinol Metab, vol. 27, pp. 782 - 795, http://dx.doi.org/10.1016/j.tem.2016.06.008

Jacobsen MJ; Mentzel CMJ; Olesen AS; Huby T; Jørgensen CB; Barrès R; Fredholm M; Simar D, 2016, 'Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity.', J Diabetes Res, vol. 2016, pp. 8539057, http://dx.doi.org/10.1155/2016/8539057

Simpson KA; Mavros Y; Kay S; Meiklejohn J; de Vos N; Wang Y; Guo Q; Zhao R; Climstein M; Baune BT, 2015, 'Graded Resistance Exercise And Type 2 Diabetes in Older adults (The GREAT2DO study): methods and baseline cohort characteristics of a randomized controlled trial.', Trials, vol. 16, pp. 512, http://dx.doi.org/10.1186/s13063-015-1037-y

Chan YL; Saad S; Simar D; Oliver B; McGrath K; Reyk DV; Bertrand PP; Gorrie C; Pollock C; Chen H, 2015, 'Short term exendin-4 treatment reduces markers of metabolic disorders in female offspring of obese rat dams.', Int J Dev Neurosci, vol. 46, pp. 67 - 75, http://dx.doi.org/10.1016/j.ijdevneu.2015.05.009

Caillaud C; Mechta M; Ainge H; Madsen AN; Ruell P; Mas E; Bisbal C; Mercier J; Twigg S; Mori TA, 2015, 'Chronic erythropoietin treatment improves diet-induced glucose intolerance in rats.', J Endocrinol, vol. 225, pp. 77 - 88, http://dx.doi.org/10.1530/JOE-15-0010

Martinez D; Palmer C; Simar D; Cameron BA; Nguyen N; Aggarwal V; Lloyd AR; Zekry A, 2015, 'Characterisation of the cytokine milieu associated with the up-regulation of IL-6 and suppressor of cytokine 3 in chronic hepatitis C treatment non-responders.', Liver Int, vol. 35, pp. 463 - 472, http://dx.doi.org/10.1111/liv.12473

Simar D; Versteyhe S; Donkin I; Liu J; Hesson L; Nylander V; Fossum A; Barrès R, 2014, 'DNA methylation is altered in B and NK lymphocytes in obese and type 2 diabetic human.', Metabolism, vol. 63, pp. 1188 - 1197, http://dx.doi.org/10.1016/j.metabol.2014.05.014

Mavros Y; Kay S; Simpson KA; Baker MK; Wang Y; Zhao RR; Meiklejohn J; Climstein M; O'Sullivan AJ; de Vos N, 2014, 'Reductions in C-reactive protein in older adults with type 2 diabetes are related to improvements in body composition following a randomized controlled trial of resistance training.', J Cachexia Sarcopenia Muscle, vol. 5, pp. 111 - 120, http://dx.doi.org/10.1007/s13539-014-0134-1

Ruell PA; Simar D; Périard JD; Best S; Caillaud C; Thompson MW, 2014, 'Plasma and lymphocyte Hsp72 responses to exercise in athletes with prior exertional heat illness.', Amino Acids, vol. 46, pp. 1491 - 1499, http://dx.doi.org/10.1007/s00726-014-1721-3

Chen H; Simar D; Pegg K; Saad S; Palmer C; Morris MJ, 2014, 'Exendin-4 is effective against metabolic disorders induced by intrauterine and postnatal overnutrition in rodents.', Diabetologia, vol. 57, pp. 614 - 622, http://dx.doi.org/10.1007/s00125-013-3132-5

Chen H; Simar D; Morris MJ, 2014, 'Maternal obesity impairs brain glucose metabolism and neural response to hyperglycemia in male rat offspring.', J Neurochem, vol. 129, pp. 297 - 303, http://dx.doi.org/10.1111/jnc.12623

Mavros Y; Kay S; Anderberg KA; Baker MK; Wang Y; Zhao R; Meiklejohn J; Climstein M; O'Sullivan A; de Vos N, 2013, 'Changes in insulin resistance and HbA1c are related to exercise-mediated changes in body composition in older adults with type 2 diabetes: interim outcomes from the GREAT2DO trial.', Diabetes Care, vol. 36, pp. 2372 - 2379, http://dx.doi.org/10.2337/dc12-2196

Simar D; Chen H; Lambert K; Mercier J; Morris MJ, 2012, 'Interaction between maternal obesity and post-natal over-nutrition on skeletal muscle metabolism.', Nutr Metab Cardiovasc Dis, vol. 22, pp. 269 - 276, http://dx.doi.org/10.1016/j.numecd.2010.11.007

Simar D; Malatesta D; Mas E; Delage M; Caillaud C, 2012, 'Effect of an 8-weeks aerobic training program in elderly on oxidative stress and HSP72 expression in leukocytes during antioxidant supplementation.', J Nutr Health Aging, vol. 16, pp. 155 - 161, https://www.ncbi.nlm.nih.gov/pubmed/22323351

Simar D; Jacques A; Caillaud C, 2012, 'Heat shock proteins induction reduces stress kinases activation, potentially improving insulin signalling in monocytes from obese subjects.', Cell Stress Chaperones, vol. 17, pp. 615 - 621, http://dx.doi.org/10.1007/s12192-012-0336-4

Chen H; Simar D; Ting JHY; Erkelens JRS; Morris MJ, 2012, 'Leucine improves glucose and lipid status in offspring from obese dams, dependent on diet type, but not caloric intake.', J Neuroendocrinol, vol. 24, pp. 1356 - 1364, http://dx.doi.org/10.1111/j.1365-2826.2012.02339.x

Maïmoun L; Simar D; Caillaud C; Coste O; Puech A-M; Jaussent A; Mariano-Goulart D; Sultan C, 2011, 'Basal plasma leptin levels in healthy elderly males are related to physical fitness without impact on bone metabolism.', J Sports Med Phys Fitness, vol. 51, pp. 160 - 168, https://www.ncbi.nlm.nih.gov/pubmed/21297576

Wang Y; Simar D; Anderberg K; Mavros Y; Kay S; Zhao R; Baune BT; O’Sullivan A; Singh N; Singh MF, 2011, 'Muscle and adipose tissue biopsy in older adults with type 2 diabetes', Journal of Diabetes Mellitus, vol. 01, pp. 27 - 35, http://dx.doi.org/10.4236/jdm.2011.13005

Malatesta D; Simar D; Ben Saad H; Préfaut C; Caillaud C, 2010, 'Effect of an overground walking training on gait performance in healthy 65- to 80-year-olds.', Exp Gerontol, vol. 45, pp. 427 - 434, http://dx.doi.org/10.1016/j.exger.2010.03.009

Maïmoun L; Simar D; Caillaud C; Coste O; Barbotte E; Peruchon E; Rossi M; Mariano-Goulart D, 2009, 'Response of calciotropic hormones and bone turnover to brisk walking according to age and fitness level.', J Sci Med Sport, vol. 12, pp. 463 - 467, http://dx.doi.org/10.1016/j.jsams.2008.05.004

Wang Y; Simar D; Fiatarone Singh MA, 2009, 'Adaptations to exercise training within skeletal muscle in adults with type 2 diabetes or impaired glucose tolerance: a systematic review.', Diabetes Metab Res Rev, vol. 25, pp. 13 - 40, http://dx.doi.org/10.1002/dmrr.928

Mavros Y; Simar D; Singh MAF, 2009, 'Glucose Tranporter-4 expression in monocytes: a systematic review.', Diabetes Res Clin Pract, vol. 84, pp. 123 - 131, http://dx.doi.org/10.1016/j.diabres.2009.02.014

Chen H; Simar D; Morris MJ, 2009, 'Hypothalamic neuroendocrine circuitry is programmed by maternal obesity: interaction with postnatal nutritional environment.', PLoS One, vol. 4, pp. e6259, http://dx.doi.org/10.1371/journal.pone.0006259

Maïmoun L; Simar D; Caillaud C; Peruchon E; Sultan C; Rossi M; Mariano-Goulart D, 2008, 'Effect of antioxidants and exercise on bone metabolism.', J Sports Sci, vol. 26, pp. 251 - 258, http://dx.doi.org/10.1080/02640410701501689

Chen H; Simar D; Lambert K; Mercier J; Morris MJ, 2008, 'Maternal and postnatal overnutrition differentially impact appetite regulators and fuel metabolism.', Endocrinology, vol. 149, pp. 5348 - 5356, http://dx.doi.org/10.1210/en.2008-0582

Simar D; Malatesta D; Badiou S; Dupuy AM; Caillaud C, 2007, 'Physical activity modulates heat shock protein-72 expression and limits oxidative damage accumulation in a healthy elderly population aged 60 90 years.', J Gerontol A Biol Sci Med Sci, vol. 62, pp. 1413 - 1419, http://dx.doi.org/10.1093/gerona/62.12.1413

Simar D; Malatesta D; Dauvilliers Y; Préfaut C; Varray A; Caillaud C, 2005, 'Aerobic and functional capacities in a selected active population of European octogenarians.', Int J Sports Med, vol. 26, pp. 128 - 133, http://dx.doi.org/10.1055/s-2004-817860

Maïmoun L; Simar D; Malatesta D; Caillaud C; Peruchon E; Couret I; Rossi M; Mariano-Goulart D, 2005, 'Response of bone metabolism related hormones to a single session of strenuous exercise in active elderly subjects.', Br J Sports Med, vol. 39, pp. 497 - 502, http://dx.doi.org/10.1136/bjsm.2004.013151

Malatesta D; Simar D; Dauvilliers Y; Candau R; Ben Saad H; Préfaut C; Caillaud C, 2004, 'Aerobic determinants of the decline in preferred walking speed in healthy, active 65- and 80-year-olds.', Pflugers Arch, vol. 447, pp. 915 - 921, http://dx.doi.org/10.1007/s00424-003-1212-y

Koechlin C; Couillard A; Simar D; Cristol JP; Bellet H; Hayot M; Prefaut C, 2004, 'Does oxidative stress alter quadriceps endurance in chronic obstructive pulmonary disease?', Am J Respir Crit Care Med, vol. 169, pp. 1022 - 1027, http://dx.doi.org/10.1164/rccm.200310-1465OC

Connes P; Caillaud C; Simar D; Villard S; Sicart M-T; Audran M, 2004, 'Strengths and weaknesses of established indirect models to detect recombinant human erythropoietin abuse on blood samples collected 48-hr post administration.', Haematologica, vol. 89, pp. 891 - 892, https://www.ncbi.nlm.nih.gov/pubmed/15257956

Simar D; Malatesta D; Koechlin C; Cristol JP; Vendrell JP; Caillaud C, 2004, 'Effect of age on Hsp72 expression in leukocytes of healthy active people.', Exp Gerontol, vol. 39, pp. 1467 - 1474, http://dx.doi.org/10.1016/j.exger.2004.08.002

Malatesta D; Simar D; Dauvilliers Y; Candau R; Borrani F; Prefaut C; Caillaud C, 2003, 'Energy cost of walking and gait instability in healthy 65- and 80-yr-olds.', J Appl Physiol (1985), vol. 95, pp. 2248 - 2256, http://dx.doi.org/10.1152/japplphysiol.01106.2002

Ying Lim M; Simar D; Chow S; Hsu K; R. Lewis C; L. Geczy C; S. Thomas P, 'S100A8, S100A9 and S100A12 Expression in Myeloid Cells from Whole Blood from Patients with Common Lung Diseases', Pulmonary and Critical Care Medicine, vol. 2, http://dx.doi.org/10.15761/pccm.1000123

Conference Papers

Conference Abstracts

Nylander V; Simar D; Aznar M; Specht L; Zierath JR; Barres R, 2014, 'Cancer therapy alters whole body metabolism later in life: a potential role for epigenetic mechanisms', in DIABETOLOGIA, SPRINGER, Vol. 57, pp. S111 - S111, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344386100248&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Lim M; Chow S; Hsu K; Lewis C; Geczy C; Thomas P; Simar D, 2014, 'S100A8, A9 AND A12 EXPRESSION BY MYELOID-DERIVED SUPPRESSOR CELLS (MDSC) IN NON-SMALL CELL LUNG CANCER (NSCLC)', in RESPIROLOGY, WILEY-BLACKWELL, Vol. 19, pp. 67 - 67, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000333238100170&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Lim M; Chow S; Hsu K; Lewis C; Simar D; Geczy C; Thomas P, 2014, 'SERUM AND EXHALED BREATH CONDENSATE (EBC) LEVELS OF S100A9, NITRITE/NITRATE (NOX) AND INTERLEUKIN-10 (IL-10) IN NON-SMALL CELL LUNG CANCER (NSCLC)', in RESPIROLOGY, WILEY-BLACKWELL, Vol. 19, pp. 68 - 68, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000333238100171&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Eslami S; Johnston K; Cohn RJ; Simar D, (eds.), 2013, 'Systemic inflammation in childhood cancer survivors treated with irradiation', 2nd International Conference on ImmunoMetabolism: Molecular and Cellular Immunology of Metabolism, Rhodes, Greece, presented at 2nd International Conference on ImmunoMetabolism: Molecular and Cellular Immunology of Metabolism, Rhodes, Greece, 15 - 20 September 2013

Baharuddin B; Simar D; Lloyd AR; Zekry A, 2013, 'Impaired T cell glucose metabolism during chronic hepatitis C virus infection', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, Vol. 28, pp. 171 - 171, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000324106900353&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Simar D; Eslami S; Cohn RJ; Johnston K; Barres R, (eds.), 2013, 'Effect of epigenetic changes on metabolic complications in childhood cancer survivors', in Keystone Symposia, Metabolic Control of Inflammation and Immunity, Beaver Run Resort, Breckenridge, Colorado, USA, presented at Metabolic Control of Inflammation and Immunity, Beaver Run Resort, Breckenridge, Colorado, USA, 21 - 24 January 2013

Mavros Y; Rooney K; Kay S; Simar D; Anderberg KA; Baker MK; Wang Y; Zhao R; Meiklejohn J; De Vos N, 2012, 'Relative Muscle Mass is Inversely Associated with Inflammation in Older Adults With Type 2 Diabetes.', in MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 44, pp. 236 - 236, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310363301299&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Baharuddin B; Zekry A; Simar D; Palmer C; Lloyd A, 2012, 'IMPAIRED T-CELL GLUCOSE METABOLISM DURING CHRONIC HEPATITIS C VIRUS INFECTION', in JOURNAL OF HEPATOLOGY, ELSEVIER SCIENCE BV, Barcelona, SPAIN, Vol. 56, pp. S302 - S302, presented at 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona, SPAIN, 18 - 22 April 2012, http://dx.doi.org/10.1016/S0168-8278(12)60782-X

Ruell P; Simar D; Pierrard J; Best S; Caillaud C; Thompson MW, (eds.), 2012, 'Exercise does not increase serum Hsp70B', in 14th Annual Congress of the European College of Sport Science, Book of Abstracts, European College of Sport Science, Bruges, Belgium, presented at 17th Annual Congress of the European College of Sport Science, Bruges, Belgium, 04 - 07 July 2012

Ainge H; Madsen A; Simar D; Ruell P; Barres R; Caillaud C, (eds.), 2012, 'ERYTHROPIETIN INCREASES FAT OXIDATION IN LEAN RATS AND IMPROVES GLUCOSE REGULATION IN HIGH FAT FED ANIMALS', in 14th Annual Congress of the European College of Sport Science, Book of Abstracts, European College of Sport Science, Bruges, Belgium, presented at 17th Annual Congress of the European College of Sport Science, Bruges, Belgium, 04 - 07 July 2012

Mavros Y; Rooney K; Kay S; Simar D; Anderberg K; Baker M; Wang Y; Zhao R; Meiklejohn J; De Vos N, 2012, 'Relative Muscle Mass is Inversely Associated with Insulin Resistance in Older Adults with Type 2 Diabetes', in Obesity Facts: the European journal of obesity, European Congress on Obesity, Lyon, France, pp. 227 - 227, presented at European Congress on Obesity, Lyon, France, 01 January 2012

Singh MAF; Mavros Y; Simar D; Anderberg KA; Kay M; Wang Y; Singh NA; O'Sullivan A, 2011, 'GLUCOSE TRANSPORTER-4 EXPRESSION IN MONOCYTES IS CORRELATED TO INDICES OF INSULIN RESISTANCE IN OLDER ADULTS WITH TYPE 2 DIABETES', in GERONTOLOGIST, OXFORD UNIV PRESS INC, Vol. 51, pp. 584 - 584, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000303602004066&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Guo Q; Wang Y; Anderberg KA; Mavros Y; Kay M; Simar D; Singh NA; Singh MAF, 2011, 'RELATIONSHIPS BETWEEN SKELETAL MUSCLE C-JUN N-TERMINAL KINASE (JNK) AND HEALTH STATUS INDICATORS IN OLDER ADULTS WITH TYPE 2 DIABETES', in GERONTOLOGIST, OXFORD UNIV PRESS INC, Vol. 51, pp. 584 - 584, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000303602004067&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Wang Y; Simar D; Anderberg KA; Mavros Y; Kay M; Baune B; Singh NA; Singh MAF, 2011, 'SKELETAL MUSCLE AND SUBCUTANEOUS ADIPOSE TISSUE ADAPTATIONS TO POWER TRAINING IN OLDER ADULTS WITH TYPE 2 DIABETES: A DOUBLE BLIND, RANDOMIZED SHAM-EXERCISE CONTROLLED TRIAL', in GERONTOLOGIST, OXFORD UNIV PRESS INC, Vol. 51, pp. 585 - 585, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000303602004068&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Guo Q; Wang Y; Mavros Y; Simar D; Anderberg KA; Kay M; Singh NA; Singh MAF, 2011, 'SKELETAL MUSCLE C-JUN N-TERMINAL KINASE (JNK) IS RELATED TO SELECTED CYTOKINES IN OLDER ADULTS WITH TYPE 2 DIABETES (T2D): BASELINE CORRELATIONS OF THE GREAT2DO STUDY', in GERONTOLOGIST, OXFORD UNIV PRESS INC, Vol. 51, pp. 23 - 23, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000303602000106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Simar D; Andrew J; Caillaud C, 2011, 'Insulin signalling in monocytes: impact of obesity', EMBO workshop 2011: Immunology and Metabolism, Marseille, France, presented at EMBO workshop 2011: Immunology and Metabolism, Marseille, France, 13 - 15 January 2011

Ting J; Simar D; Morris MJ; Chen H, 2010, 'Leucine supplement improved glucose metabolism in offspring from obese dams via altering muscle and liver markers', in Obesity Research & Clinical Practice, Elsevier BV, Vol. 4, pp. S66 - S67, http://dx.doi.org/10.1016/j.orcp.2010.09.130

Fatseas G; Simar D; Caillaud C, (eds.), 2009, 'Heat acclimation and activation of a cytoprotective pathway', in 14th Annual Congress of the European College of Sport Science, Book of Abstracts, European College of Sport Science, Oslo, Norway, pp. 252 - 253, presented at 14th Annual Congress of the European College of Sport Science, Oslo, Norway, 24 - 27 June 2009

Caillaud C; Trout G; Howe C; Simar D; Fatseas G; Howe C, (eds.), 2009, 'Does exercise in hot environmental condition impair detection of erythropoietin doping?', in 14th Annual Congress of the European College of Sport Science, Book of Abstracts, European College of Sport Science, Oslo, Norway, pp. 536 - 536, presented at 14th Annual Congress of the European College of Sport Science, Oslo, Norway, 24 - 27 June 2009

Simar D; Fatseas G; Caillaud C, (eds.), 2009, 'Insulin resistance in obesity: a new cellular model', in 14th Annual Congress of the European College of Sport Science, Book of Abstracts, European College of Sport Science, Oslo, Norway, pp. 502 - 502, presented at 14th Annual Congress of the European College of Sport Science, Oslo, Norway, 24 - 27 June 2009

Maimoun L; Simar D; Caillaud C; Coste O; Puechv AA; Peruchon E; Jaussent A; Rossi M; Sultan C; Mariano-Goulart D, 2008, 'In elderly healthy subjects, the physical fitness level plays a crucial role in the leptin secretion and bone turnover', in FUNDAMENTAL & CLINICAL PHARMACOLOGY, BLACKWELL PUBLISHING, Vol. 22, pp. 43 - 43, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000256760500206&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a