
Dr Blake Cochran
Fields of research: Animal Cell and Molecular Biology, Biochemistry and Cell Biology, Endocrinology, Cardiology (incl. Cardiovascular Diseases), Cell Metabolism
Contact Details
Phone: (02) 9385 2910
Email: b.cochran@unsw.edu.au
Tabs
Publications related to this Person
Journal articles
Cochran B; Ong K; Rye K-A; Manandhar B, 2021, 'APOA1: a Protein with Multiple Therapeutic Functions', Current Atherosclerosis Reports, http://dx.doi.org/10.1007/s11883-021-00906-7
Tucker B; Sawant S; McDonald H; Rye KA; Patel S; Ong KL; Cochran BJ, 2021, 'The association of serum lipid and lipoprotein levels with total and differential leukocyte counts: Results of a cross-sectional and longitudinal analysis of the UK Biobank', Atherosclerosis, vol. 319, pp. 1 - 9, http://dx.doi.org/10.1016/j.atherosclerosis.2020.12.016
Vaidya K; Tucker B; Kurup R; Khandkar C; Pandzic E; Barraclough J; Machet J; Misra A; Kavurma M; Martinez G; Rye KA; Cochran BJ; Patel S, 2021, 'Colchicine inhibits neutrophil extracellular trap formation in patients with acute coronary syndrome after percutaneous coronary intervention', Journal of the American Heart Association, vol. 10, pp. 1 - 13, http://dx.doi.org/10.1161/JAHA.120.018993
Wang H; Leeming MG; Cochran BJ; Hook JM; Ho J; Nguyen GTH; Zhong L; Supuran CT; Donald WA, 2020, 'Nontargeted Identification of Plasma Proteins O-, N-, and S-Transmethylated by O-Methyl Organophosphates', Analytical Chemistry, vol. 92, pp. 15420 - 15428, http://dx.doi.org/10.1021/acs.analchem.0c03077
Yadav S; Dudchenko O; Esvaran M; Rosen B; Field M; Skvortsova K; Gopalakrishnan S; Keilwagen J; Cockran B; Manandhar B; Bucknall M; Bustamante S; Rasmussen J; Melvin R; Omer A; Colaric, Z; Chan E; Minoche A; Smith T; Gilbert T; Bogdanovic O; Zammit R; Thomas T; Aiden E; Ballard B, 2020, 'Desert Dingo (Canis lupus dingo) genome provides insights into their role in the Australian ecosystem', bioRix, http://dx.doi.org/10.1101/2020.11.15.384057
Manandhar B; Cochran BJ; Rye KA, 2020, 'Role of High-Density Lipoproteins in Cholesterol Homeostasis and Glycemic Control', Journal of the American Heart Association, vol. 9, pp. e013531, http://dx.doi.org/10.1161/JAHA.119.013531
Lai YC; Woollard KJ; McClelland RL; Allison MA; Rye KA; Ong KL; Cochran BJ, 2019, 'The association of plasma lipids with white blood cell counts: Results from the Multi-Ethnic Study of Atherosclerosis', Journal of Clinical Lipidology, vol. 13, pp. 812 - 820, http://dx.doi.org/10.1016/j.jacl.2019.07.003
Hou L; Tang S; Wu BJ; Ong KL; Westerterp M; Barter PJ; Cochran BJ; Tabet F; Rye KA, 2019, 'Apolipoprotein A-l improves pancreatic β-cell function independent of the ATP-binding cassette transporters ABCA1 and ABCG1', FASEB Journal, vol. 33, pp. 8479 - 8489, http://dx.doi.org/10.1096/fj.201802512RR
Hackett MJ; Hollings A; Majimbi M; Brook E; Cochran B; Giles C; Lam V; Nesbit M; Rye KA; Mamo JCL; Takechi R, 2019, 'Multimodal Imaging Analyses of Brain Hippocampal Formation Reveal Reduced Cu and Lipid Content and Increased Lactate Content in Non-Insulin-Dependent Diabetic Mice', ACS Chemical Neuroscience, vol. 10, pp. 2533 - 2540, http://dx.doi.org/10.1021/acschemneuro.9b00039
Kopecky C; Pandzic E; Parmar A; Szajer J; Lee V; Dupuy A; Arthur A; Fok S; Whan R; Ryder WJ; Rye KA; Cochran BJ, 2019, 'Translocator protein localises to CD11b + macrophages in atherosclerosis', Atherosclerosis, vol. 284, pp. 153 - 159, http://dx.doi.org/10.1016/j.atherosclerosis.2019.03.011
Cochran B; Tang S; Tabet F; Cuesta Torres L; Wu B; Barter P; Rye K-A, 2019, 'Apolipoprotein A-I enhances insulin-dependent and insulinindependent glucose uptake by skeletal muscle', Scientific Reports, vol. 9, http://dx.doi.org/10.1038/s41598-018-38014-3
Jones B; Buenaventura T; Kanda N; Chabosseau P; Owen BM; Scott R; Goldin R; Angkathunyakul N; Corrêa IR; Bosco D; Johnson PR; Piemonti L; Marchetti P; Shapiro AMJ; Cochran BJ; Hanyaloglu AC; Inoue A; Tan T; Rutter GA; Tomas A; Bloom SR, 2018, 'Targeting GLP-1 receptor trafficking to improve agonist efficacy', Nature Communications, vol. 9, http://dx.doi.org/10.1038/s41467-018-03941-2
Barter PJ; Cochran BJ; Rye KA, 2018, 'CETP inhibition, statins and diabetes', Atherosclerosis, vol. 278, pp. 143 - 146, http://dx.doi.org/10.1016/j.atherosclerosis.2018.09.033
Aleidi SM; Yang A; Sharpe LJ; Rao G; Cochran BJ; Rye KA; Kockx M; Brown AJ; Gelissen IC, 2018, 'The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages', Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, vol. 1863, pp. 359 - 368, http://dx.doi.org/10.1016/j.bbalip.2017.12.011
Cochran BJ; Ryder W; parmar A; Meikle S; Barter P; Rye K, 2017, 'Determining Glucose Metabolism Kinetics Using 18F-FDG Micro-PET/CT', Journal of Visualized Experiments, vol. 2017, http://dx.doi.org/10.3791/55184
Pandzic E; Gelissen IC; Whan R; Barter PJ; Sviridov D; Gaus K; Rye KA; Cochran BJ, 2017, 'The ATP binding cassette transporter, ABCG1, localizes to cortical actin filaments', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/srep42025
Cochran BJ; Hou L; Manavalan APC; Moore BM; Tabet F; Sultana A; Torres LC; Tang S; Shrestha S; Senanayake P; Patel M; Ryder WJ; Bongers A; Maraninchi M; Wasinger VC; Westerterp M; Tall AR; Barter PJ; Rye K-A, 2017, 'Impact of Perturbed Pancreatic beta-Cell Cholesterol Homeostasis on Adipose Tissue and Skeletal Muscle Metabolism (vol 65, pg 3610, 2016)', DIABETES, vol. 66, pp. 560 - 560, http://dx.doi.org/10.2337/db17-er02b
Cochran BJ; Hou L; Manavalan APC; Moore BM; Tabet F; Sultana A; Torres LC; Tang S; Shrestha S; Senanayake P; Patel M; Ryder WJ; Bongers A; Maraninchi M; Wasinger VC; Westerterp M; Tall AR; Barter PJ; Rye KA, 2016, 'Impact of perturbed pancreatic β-cell cholesterol homeostasis on adipose tissue and skeletal muscle metabolism', Diabetes, vol. 65, pp. 3610 - 3620, http://dx.doi.org/10.2337/db16-0668
Cochran BJ; Ryder WJ; Parmar A; Tang S; Reilhac A; Arthur A; Charil A; Hamze H; Barter PJ; Kritharides L; Meikle SR; Gregoire MC; Rye KA, 2016, 'In vivo PET imaging with [18F]FDG to explain improved glucose uptake in an apolipoprotein A-I treated mouse model of diabetes', Diabetologia, vol. 59, pp. 1977 - 1984, http://dx.doi.org/10.1007/s00125-016-3993-5
Sultana A; Cochran BJ; Tabet F; Patel M; Cuesta Torres L; Barter PJ; Rye K, 2016, 'Inhibition of inflammatory signaling pathways in 3T3-L1 adipocytes by apolipoprotein A-I', The FASEB Journal, vol. 30, pp. 2324 - 2335, http://dx.doi.org/10.1096/fj.201500026R
Rye KA; Barter PJ; Cochran BJ, 2016, 'Apolipoprotein A-I interactions with insulin secretion and production', Current Opinion in Lipidology, vol. 27, pp. 8 - 13, http://dx.doi.org/10.1097/MOL.0000000000000253
Cochran BJ; Bisoendial RJ; Hou L; Glaros E; Rossy J; Thomas SR; Barter PJ; Rye KA, 2014, 'Apolipoprotein a-I increases insulin secretion and production from pancreatic β-cells via a g-protein-camp-PKA-FOXO1-dependent mechanism', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 34, pp. 2261 - 2267, http://dx.doi.org/10.1161/ATVBAHA.114.304131
Lee JA; Cochran BJ; Lobov S; Ranson M, 2011, 'Forty years later and the role of plasminogen activator inhibitor type 2/SERPINB2 is still an enigma', Seminars in Thrombosis and Hemostasis, vol. 37, pp. 395 - 407, http://dx.doi.org/10.1055/s-0031-1276589
Cochran BJ; Saunders D; Croucher DR; Lobov S; Ranson M, 2011, 'Dependence on endocytic receptor binding via a minimal binding motif underlies the differential prognostic profiles of serpinE1 and serpinB2 in cancer', The Journal of Biological Chemistry, vol. 286, pp. 24467 - 24475, http://dx.doi.org/10.1074/jbc.M111.225706
Cochran BJ; Gunawardhana LP; Vine KL; Lee JA; Lobov S; Ranson M, 2009, 'The CD-loop of PAI-2 (SERPINB2) is redundant in the targeting, inhibition and clearance of cell surface uPA activity', BMC Biotechnology, vol. 9, http://dx.doi.org/10.1186/1472-6750-9-43
Conference Papers
Dunn K; Cochran B; Haeusler M; Cheng T, 2019, 'Design in Paediatric Healthcare: Rethinking 3D models of paediatric orthopaedic data using Design approaches.', in Fairly A (ed.), Real / Material / Etheral, Monash University, Monash University Melbourne, presented at 2nd Annual Design Research Conference, Monash University Melbourne, 03 October 2019 - 04 October 2019, https://www.monash.edu/design-research-conference#links&downloads
Cochran BJ; Trajanovska S; Sunn N; Rye KA; Ryder WJ, 2018, 'Development of 3D printing filaments for bespoke X-Ray phantoms', in 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2018 - Proceedings, IEEE, presented at 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 10 November 2018 - 17 November 2018, http://dx.doi.org/10.1109/NSSMIC.2018.8824621
Kopecky CM; Ryder WJ; Szajer J; Parmar A; Pandzic E; Rye KA; Cochran BJ, 2018, 'Translocator Protein as Novel Marker for Early Atherosclerosis', in ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, San Francisco, CA, presented at Scientific Sessions of the American-Heart-Association on Vascular Discovery - From Genes to Medicine, San Francisco, CA, 10 May 2018 - 12 May 2018, http://dx.doi.org/10.1161/atvb.38.suppl_1.222
Conference Presentations
Manandhar B; Cochran BJ; Rye K, 2019, 'APOLIPOPROTEIN A-I LOCALISES TO MITOCHONDRIA AND INHIBITS ROS GENERATION IN INSULIN PRODUCING CELLS.', Victoria University City Convention Centre, Melbourne, presented at AAS 2019 Annual Scientific meeting, Victoria University City Convention Centre, Melbourne, 16 October 2019 - 19 October 2019
Tucker B; Rehan R; Vaidya K; Rye K; Cochran B; Patel S, 2019, 'Colchicine inhibits neutrophil extracellular trap formation in acute coronary syndrome patients', Melbourne, presented at Australian Atherosclerosis Society Annual Scientific Meeting, Melbourne, 16 October 2019 - 19 October 2019
Tan WT; Kopecky C; Manandhar B; Rye K-A; Cochran B, 2019, 'Skeletal Muscle Specific Deletion Of Abca1 And Abcg1 Impacts Body Composition And Metabolism And Is Age Dependent', presented at 87th European Atherosclerosis Society Congress, 26 May 2019, http://dx.doi.org/10.1016/j.atherosclerosis.2019.06.122
Conference Abstracts
Cochran BJ; Pinheiro D; Prendecki M; Jones B; Cegla J; Lee V; Barter PJ; Murphy AJ; Rye K-A; Woollard KJ, 2018, 'PRO-ATHEROSCLEROTIC LOW-DENSITY NEUTROPHILS ARE PRESENT IN HYPERCHOLESTEROLEMIA', in ATHEROSCLEROSIS SUPPLEMENTS, ELSEVIER IRELAND LTD, Toronto, CANADA, Vol. 32, pp. 39 - 40, presented at International Symposium on Atherosclerosis (ISA), Toronto, CANADA, 09 June 2018 - 12 June 2018, http://dx.doi.org/10.1016/j.atherosclerosissup.2018.04.115
Kopecky C; Ryder WJ; Szajer J; Parmar A; Pandzic E; Rye K-A; Cochran BJ, 2018, 'THE TSPO RADIOLIGAND 18F-PBR111 AS A PRE-ATHEROSCLEROTIC LESION DETECTION AGENT', in ATHEROSCLEROSIS SUPPLEMENTS, ELSEVIER IRELAND LTD, Toronto, CANADA, Vol. 32, pp. 145 - 146, presented at International Symposium on Atherosclerosis (ISA), Toronto, CANADA, 09 June 2018 - 12 June 2018, http://dx.doi.org/10.1016/j.atherosclerosissup.2018.04.446
Polly P; Jones G; Cochran B, 2017, 'EMENTORING TO SUPPORT AND ENABLE RESEARCH INTEGRATED LEARNING USING AUTHENTIC ASSESSMENT IN A THIRD YEAR UNDERGRADUATE SCIENCE COURSE IN PATHOLOGY AT A RESEARCH INTENSIVE UNIVERSITY', in EDULEARN17 Proceedings, 9th International Conference on Education and New Learning Technologies, presented at 9th International Conference on Education and New Learning Technologies
Cochran BJ; Hou L; Manavalan APC; Sultana A; Moore BM; Patel M; Tall A; Barter PJ; Rye KA, 2015, 'PANCREATIC BETA-CELL SPECIFIC DELETION OF ABCA1 AND ABCG1 PERTURBS GLUCOSE METABOLISM AND INCREASES ADIPOSITY IN MICE DUE TO SUBOPTIMAL PLASMA INSULIN LEVELS', in ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, Glasgow, SCOTLAND, Vol. 241, pp. E3 - E3, presented at 83rd Congress of the European-Atherosclerosis-Society (EAS), Glasgow, SCOTLAND, 22 March 2015 - 25 March 2015, http://dx.doi.org/10.1016/j.atherosclerosis.2015.04.028
Media
Cochran B; Dunn K, 2020, Australia's 3D printing experts are banding together to make masks for at-risk health workers
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