Hypoxia-inducible factor-1 (HIF-1): Pharmacological and molecular insights into its role in brain protection

Project members:

Project main description:

At present, there are no effective therapies for reducing brain damage which can occur after acute brain insults including birth asphyxia. This project aims to study whether increasing a naturally occurring protective protein (HIF) in the brain can minimize brain damage in a model of perinatal brain injury. We plan to validate HIF as a novel therapeutic target for reduce brain injury and promote brain repair repair processes.

Project supporters:

  • National Health & Medical Research Council - Project Grant|568769