Speaker: Prof Avrum Gotlieb/ University of Toronto
School or Unit : School of Medical Sciences
Location of the event : Athol Lykke Theatre, Wallace Wurth Building, Level 5, UNSW
Event Type : CVR and UNSW Cancer Research Centre Seminar Series
Details :Title: Activated Valve Interstitial Cells Repair Diseased Heart Valves
Valve interstitial cells (VICs) undergo activation and phenotypic changes in response to
valve injury and disease. We show that mechanical wounding of in vitro monolyers
activates VICs and up-regulates TGF-b. Exogenous TGF-b regulates VIC activation and
modulates VIC proliferation, apoptosis and wound closure. In conclusion, TGF-b is an
important cytokine in regulation VIC wound repair.
Date Details
Start : 10:00 AM, 10-Jun-08
Finish : 11:00 AM, 10-Jun-08
Open to : University Staff and Students
Cost : FREE
Contact Details
Contact : Levon Khachigian
Phone :
Fax :
Email :
More Information
Prof Avrum Gotlieb is from the Department of Laboratory Medicine and Pathobiology at the University of Toronto in Canada