Mitochondria are the primary site of energy production within cells. Mitochondrial dysfunction has been linked with a number of inherited and acquired human diseases and has also been implicated in the ageing process. A major focus of our studies is to examine how alterations in mitochondrial function in different tissues influences insulin action in obesity and type 2 diabetes.
We are interested in how certain drugs and different types of dietary fats affect mitochondrial content and metabolism. We are also examining the role of post-translational modification in the function of mitochondrial proteins. Another area of research is the importance of alterations in mitochondrial bioenergetics in certain types of cancers.
Past Lab Members:
Dr Magda Montgomery, Research Fellow, Monash University
Dr Sanket Joshi, Research Fellow UNSW
Professor David Sinclair, UNSW Sydney and Harvard Medical School, Boston
Professor Gregory Cooney, Charles Perkins Centre, University of Sydney
Grants & Funding
Funding is provided by the National and Medical Health Research Council, the Australian Research Council, Diabetes Australia Research Trust and the Mostyn Family Foundation.
- Jayne Barbour (PhD)
- Menghan Liu (PhD)
- Nicholas Bentley (PhD)
- Ghazal Sultani (PhD)
- Azrah Samsudeen (Honours)
- Louise Metcalfe (Honours)
Please contact us for current opportunities for talented Honours students in 2017