Mitochondrial bioenergetics

About us

Research Focus

Mitochondria are the primary site of energy production within cells. Mitochondrial dysfunction has been linked with a number of inherited and acquired human diseases and has also been implicated in the ageing process. A major focus of our studies is to examine how alterations in mitochondrial function in different tissues influences insulin action in obesity and type 2 diabetes.

We are interested in how certain drugs and different types of dietary fats affect mitochondrial content and metabolism. We are also examining the role of post-translational modification in the function of mitochondrial proteins. Another area of research is the importance of alterations in mitochondrial bioenergetics in certain types of cancers.

 

image - Mitochondrial bioenergetics

 

 

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Team

Collaborators

Past Lab Members:

Dr Magda Montgomery, Research Fellow, Monash University

Dr Sanket Joshi, Research Fellow UNSW

Collaborators:

Professor David Sinclair, UNSW Sydney and Harvard Medical School, Boston

Professor Gregory Cooney, Charles Perkins Centre, University of Sydney

 

Grants & Funding

Funding is provided by the National and Medical Health Research Council, the Australian Research Council, Diabetes Australia Research Trust and the Mostyn Family Foundation.

Students

  • Jayne Barbour (PhD)
  • Menghan Liu (PhD)
  • Nicholas Bentley (PhD)
  • Ghazal Sultani (PhD)
  • Azrah Samsudeen (Honours)
  • Louise Metcalfe (Honours)

Please contact us for current opportunities for talented Honours students in 2017