Environmental Determinants of Obesity

Leigh S-J, Kaakoush NO, Westbrook RF, Morris MJ (2020) Minocycline-induced microbiome alterations predict cafeteria diet-induced spatial recognition memory impairments in rats. Transl Psychiatry  (In press) 


Bertoldo MJ, Listijono DR, Ho HJ, Riepsamen AH, Morris MJ et al (2020) NAD+ repletion rescues female fertility during reproductive aging. CELL-REPORTS, p.721985. doi: https://doi.org/10.1101/721985

Kong WL, Huang Y, Qian E, Morris MJ (2019) Constipation and Probable Rapid Eye Movement Sleep Behavior Disorder Associate with Cognitive Processing Speed and Attention over Five Years Following Clinical Diagnosis in Males with Parkinson’s Disease'.Translational Neurodegeneration (under review.)

*Leigh SJ, Kaakoush NO, Westbrook RF, Morris MJ (2019) Intermittent cafeteria diet identifies body length and fecal microbiome changes as predictors of diet-induced cognitive impairment in female rats. Translational Psychiatry , 10(1), pp.1-12.

* Leigh, S. J., Kendig, M. D., & Morris, M. J. (2019). Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents. J Vis Exp, (153). doi:10.3791/60262 PMID: 31736485

Kendig MD, Westbrook RF, Morris MJ (2019) Pattern of access to cafeteria-style diet determines fat mass and degree of spatial memory impairments in rats. Scientific Reports 18;9(1):13516. PMID: 31534169

Zieba J, Morris MJ, Weickert CS, Karl T (2019) Behavioural effects of high fat diet in adult Nrg1 type III transgenic mice. Behav Brain Res 112217 PMID:31499092

Youngson NA, Uddin GM, Das A, Martinez C, Connaughton HS, Whiting S, Yu J, Sinclair DA, Aitken RJ, Morris MJ (2019) Impacts of obesity, maternal obesity and nicotinamide mononucleotide supplementation on sperm quality in mice. Reproduction (Cambridge, England) 158(2):171-181 PMID: 31226694 

Deng F, Li Y, Hossain Md, Kendig M, Arnold R, Morris MJ, Goldys E, Liu G (2019) Polymer brush based fluorescent immunosensor for direct monitoring of interleukin-1β in rat blood. Analyst PMID: ID: 31418433 

Zieba J, Morris MJ, Karl T (2019) Behavioural effects of high fat diet exposure starting in late adolescence in neuregulin 1 transmembrane domain mutant mice. Behavioural Brain Research 373 PMID: 31284014 

Zieba J, Uddin GM, Youngson NA, Karl T, Morris MJ (2019) Long-term behavioural effects of maternal obesity in C57BL/6J mice. Physiology and Behavior 199:306-313 PMID: 30414884 

Grant R, Pawlak R, Vos P, Bilgin AA, Berg J, Pearce R, Morris M (2019) Cardiovascular Disease Risk Factors Profile Among Australian Vegetarian and Nonvegetarian Teenagers. American Journal of Lifestyle Medicine 155982761982900-155982761982900

*Srinivasan SBP, *Raipuria M, *Bahari H, Kaakoush NO; Morris MJ (2018) Impacts of diet and exercise on maternal gut microbiota are transferred to offspring. FRONT in ENDOCRINOLOGY 9: 12 pages Article number ARTN 716

Morris MJ, Hesson LB, Poulos R, Ward R, Wong JWH, Youngson NY (2018) Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation. Biomarker Research 6(1)

Ali I, Gandrathi A, Zheng T, Morris MJ, O'Brien TJ, French C. (2018) Neuropeptide Y Affects Thalamic Reticular Nucleus Neuronal Firing and Network Synchronisation Associated with Suppression of Spike-Wave Discharges EPILEPSIA 59(7):1444-1454 PMID: 29923603

Bertoldo MJ, *Uddin GM, Youngson NA, Agapiou D, Walters KA, Sinclair DA, Morris MJ, Gilchrist RB. (2018) Multigenerational obesity-induced perturbations in oocyte-secreted factor signalling can be ameliorated by exercise and nicotinamide mononucleotide. Human Reproduction Open. 2018(3):hoy010. PMID:30895251

Gokarn R, Solon-Biet S, Youngson NA, Wahl D, Cogger VC, McMahon AC, Cooney GJ, Ballard JWO, Raubenheimer D, Morris MJ et al (2018) The Relationship between Dietary Macronutrients and Hepatic Telomere Length in Aging Mice. Journals of Gerontology - Series A Biological Sciences and Medical Sciences 73(4):446-449 PMID: 30052781

Powell K, Fitzgerald X, Shallue C, Jovanovska V, Klugmann M, Von Jonquieres G, O’Brien TJ, Morris MJ (2018) Gene therapy mediated seizure suppression in Genetic Generalised Epilepsy: Neuropeptide Y overexpression in a rat model. Neurobiology of Disease 113:23-32. PMID:29414380

*Beilharz JE, Kaakoush NO, Maniam J, Morris MJ (2018) Cafeteria diet and probiotic therapy: Cross-talk among memory, neuroplasticity, serotonin receptors, and gut microbiota in the rat. Molecular Psychiatry 23(2):351-361. PMID:28289278

Ong, KL, Morris MJ et al (2018) Relationship of lipids and lipid-lowering medications with cognitive function: The Multi-Ethnic Study of Atherosclerosis. American Journal of Epidemiology. 187(4):767-776. PMID:29617947

*Uddin GM, Youngson NA, *Doyle BM, Sinclair DA, Morris MJ (2017) Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice: Comparison with exercise. Scientific Reports 7(1) PMID:29118320

*Teo J, Morris MJ, Jones NJ (2017) Maternal obesity increases inflammation and exacerbates damage following neonatal hypoxic-ischemic brain injury in rats Brain, Behav Immunity 63: 186-196 pii: S0889-1591(16)30473-1. 22746168

*Teo J, Morris MJ, Jones NC (2017) Hypoxic postconditioning improves behavioural deficits at 6 weeks following hypoxic-ischemic brain injury in neonatal rats. Behavioral Brain Research 333, 27-34. PMID:28647597

Kaakoush NO, Lecomte V, Maloney CA, Morris MJ (2017) Cross-talk among metabolic parameters, esophageal microbiota, and host gene expression following chronic exposure to an obesogenic diet.  Scientific Reports 7:15753. PMID:28362001

Lecomte V, Maloney CA, *Wang KW, Morris MJ (2017) Effects of paternal obesity on growth and adiposity of male rat offspring. Am J Physiol Endocrinol Metab   312(2): E117-E125 [editor’s pick]. PMID:27965204

Kaakoush NO#, Martire SI#*, Raipuria M*, Mitchell HM, Nielsen S, Westbrook RF, Morris MJ (2017) Alternating or continuous exposure to cafeteria diet leads to similar shifts in gut microbiota compared to chow diet Molec Nutrition Food Res 61(1) doi:10.1002/mnfr.201500815 PMID:26767716

*Chowdhury MK, Turner NJ, Morris MJ, Shepherd P, Smith G. (2017) Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes. Scientific Reports 7:40159 PMID:28054648

Barry, G Briggs JA, Hwang DW, Nayler SP, Fortuna PRJ, Jonkhout N, Dachet F, Maag J, Mestdagh P, Singh E, Avesson l, Kaczorowski DC, Ozturk E, Jones NC, Vetter I, Arriola-Martinez L, Hu J, Franco GR, Warn V, Gong A, Dinger M, Rigo F, Lipovich L, Morris MJ, O’Brien TJ, Lee DS, Loeb J, Blackshaw S, Mattick J, Wolvetang E. (2017) The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states.  Scientific Reports 7, Article number: 40127 doi:10.1038/srep40127PMID:28054653

*Chowdhury SS, Lecomte V, Erlich JV, Maloney CA, Morris MJ (2016) Paternal high fat diet leads to renal accumulation of lipid and tubular changes in adult offspring.  Nutrients 8(9) doi: 10.3390/nu8090521. PMID:27563922

Ong KL, Morris MJ, McClelland RL, Maniam J, Allison MA, Rye KA (2016) Lipids, lipoprotein distribution and depressive symptoms: the multi-ethnic study of atherosclerosis.  Translational Psychiatry 6(11) e962 PMID:27898070

*Uddin GM, Youngson NY, Sinclair DA, Morris MJ (2016) Head to head comparison of short-term treatment with the NAD(+) Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in obese Female Mice.  Front Pharmacology 7:258. doi: 10.3389/fphar.2016.00258 PMID:27594836

*Beilharz JE, Maniam J, Morris MJ (2016) Short-term exposure to a diet high in fat and sugar, or liquid sugar, selectively impairs hippocampal-dependent memory, with differential impacts on inflammation Behavioral Brain Research  306, 1-7. PMID:26970578

Reichelt AC, Abbott KN, Morris MJ, Westbrook RF (2016) Differential motivational profiles following adolescent sucrose access in male and female rats Physiology and Behaviour 157, 13-19 PMID:26826605

*Beilharz J, Kaakoush NO, Maniam J, Morris MJ (2016) The effect of short-term exposure to energy-matched diets enriched in fat or sugar on memory, gut microbiota and markers of brain inflammation and plasticity Brain, Behav Immunity 57, 304-13 PMID:27448745

*Chowdhury MK, Wu LE, Coleman JL, Smith NJ, Morris MJ, Shepherd PR, Smith GC. (2016) Niclosamide blocks glucagon phosphorylation of Ser552 on β-catenin in primary rat hepatocytes via PKA signalling. Biochem J, 473(9), 1247-1255. PMID:26964897

Maniam J, Antoniadis CP, Le V, Morris MJ. (2016) A diet high in fat and sugar reverses anxiety-like behaviour induced by limited nesting in male rats: Impacts on hippocampal markers. Psychoneuroendocrinology, 68, 202-209. PMID:26999723

Reichelt AC, Morris MJ, Westbrook RF (2016) Daily access to sucrose impairs aspects of spatial memory tasks reliant on pattern separation and neural proliferation in rats.  Learning and Memory 23(7) 386-390. PMID:27317199

Abbott KN, Morris MJ, Westbrook RF, Reichelt A (2016) Sex-specific effects of daily exposure to sucrose on spatial memory performance in male and female rats, and implications for estrous cycle stage Physiology and Behaviour 162: 52-60 PMID:26828038

Dezsi G, Ozturk E, Salzberg MR, Morris M, O'Brien TJ, Jones NC, (2016) Environmental enrichment imparts disease-modifying and transgenerational effects on genetically-determined epilepsy and anxiety., Neurobiol Dis, 93: 129 – 136 PMID:27185593

Yang M, Ozturk E, Salzberg MR, Rees S, Morris MJ, O’Brien TJ, Jones NC (2016) Environmental enrichment delays limbic epileptogenesis and restricts pathological synaptic plasticity. Epilepsia, 57(3):484-494, doi:10.1111/epi.13299 PMID:26786278

Youngson NA, Lecomte V, Maloney CA, Leung P, Liu J, Hesson LB, Luciani F, Krause L, Morris MJ (2016) Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring Asian Journal of Andrology, 18(6):930-936 doi: 10.4103/1008-682X.163190 PMID:26608942

Sharpe M, Clemens K, Morris MJ, Westbrook RF (2016) Daily exposure to sucrose impairs subsequent learning about food cues: A role for alterations in ghrelin signalling and dopamine D2 receptors. Neuropsychopharmacology, 41(5):1357-1365 (Epub 14 Sept 2015) doi: 10.1038/npp.2015.287 PMID:26365954

Maniam J, Antoniadis CP, Youngson NA, Sinha JK, Morris MJ (2016) Sugar consumption produces effects similar to early life stress exposure on hippocampal markers of neurogenesis and stress response. Front Molec Neuroscience 8. doi:10.3389/fnmol.2015.00086PMID:26834554

Maniam J, Antoniadis CP, Wang K, Morris MJ (2015) Early life stress induced by limited nesting material produces a metabolic resilience in response to a high-fat and high-sugar diet in male rats.  Frontiers Endocrinology 6:138 doi:10.3389/fendo.2015.00138 PMID:26441828

*Chowdhury MK, Montgomery MK, Morris MJ, Cognard E, Shepherd PR, Smith GC. (2015) Glucagon phosphorylates serine 552 of b-catenin leading to increased expression of cyclin D1 and c-Myc in the isolated rat liver.  Archives of Physiology & Biochemistry  121(3):88-96 doi:10.3109/13813455.2015.1048693 PMID:26135564

Maniam J, Antoniadis C, Morris MJ (2015) The effect of early life stress and chronic high sucrose diet on metabolic outcomes in female rats. Stress 18(5):524-37. doi: 10.3109/10253890. PMID:26365331

Grant R, Bilgin A, Guest J, Morris MJ, Garg M, Pearce R (2015) The Relative Value of Measures of Omega-3 Index, Perceived Stress, Cortisol and Sleep Time in Identifying Depression Among a Cohort of Australian Adolescents. International Journal of Child Health &Nutrition 4, 40-49. 

*Raipuria M#, Hardy GO#, Bahari H, Morris MJ (2015) Maternal obesity regulates gene expression in the hearts of offspring. Nutr Metab Cardiovascular Diseases 25(9):881-8. PMID:26224356

Lecomte V#, Kaakoush N#, Maloney C  Raipuria M*, Huinao  K, Mitchell H, Morris MJ (2015)   Changes in gut microbiota in rats fed a high fat diet correlate with obesity-associated metabolic parameters. PloSOne May 18 10(5) e:0126931 PMID:25992554

*Raipuria M, Bahari H, Morris MJ (2015) Effects of maternal diet and exercise during pregnancy on glucose metabolism in skeletal muscle and fat of weanling rats.  PloSOne Apr 8 10(4) e:0120980 PMID:25853572

Teo J, Morris MJ, Jones NM (2015) Hypoxic postconditioning reduces microglial activation, astrocyte and caspase activity and inflammatory markers after hypoxia-ischaemia in the neonatal rat brain Pediatric Research 77, 757-764. PMID:25751571

Zabeau L, Jensen CJ, Seeuws S, Venken K, Verhee A, Catteeuw D, van Loo G, Chen H, Walder K, Hollis J, Foote S, Morris MJ, Van der Heyden J, Peelman F, Oldfield BJ, Rubio, JP, Elewaut D, Tavernier J.  (2015) Leptin’s metabolic and immune functions can be uncoupled at the ligand/receptor interaction level. Cellular and Molecular Life Sciences 72:629-644 PMID:25098352

Reichelt AC, Maniam J, Westbrook RF, Morris MJ (2015) Dietary-induced obesity disrupts trace fear conditioning and decreases hippocampal reelin expression.  Brain, Behavior, and Immunity    43:68-75. doi:10.1016/j.bbi.2014.07.005. PMID:25043993

Reichelt AC, Killcross S, Hambly LD, Morris MJ, Westbrook FR. (2015) Impact of adolescent sucrose access on cognitive control, recognition memory and parvalbumin immunoreactivity.   Learning and Memory   22(4) 215-224. PMID:25776039

*Martire SI, Westbrook RF, Morris M  (2015) Effects of long-term cycling between palatable cafeteria diet and regular chow on intake, eating patterns, and response to saccharin and sucrose.  Physiology & Behavior   139: 80-88. PMID:25446218

Khor A, Grant R, Tung C, Guest J, Pope B, Morris M, Bilgin A.  (2014) Postprandial oxidative stress is increased after a phytonutrient-poor food but not after a kilojoule-matched phytonutrient-rich food.  Nutrition Research Volume 34(5): 391-400 doi:10.1016/j.nutres.2014.04.005 PMID:24916552

Reichelt AC, Morris MJ, Westbrook RF (2014) Cafeteria diet impairs expression of sensory-specific satiety and stimulus-outcome learning.  Frontiers in Psychology 5:852. doi: 10.3389/fpsyg.2014.00852. PMID:25221530

Chen H, Simar D, Pegg K, Saad S, Palmer C, Morris MJ (2014) Exendin-4 is effective against metabolic disorders induced by intrauterine and postnatal overnutrition in rodents. Diabetologia, 57(3) pp 614-622 PMID:24337156

Koe AS, Salzberg MR, Morris MJ, O'Brien TJ, Jones NC (2014) Early life maternal separation stress augmentation of limbic epileptogenesis: the role of corticosterone and HPA axis programming.  Psychoneuroendocrinology 42:124-33. doi: 10.1016/j.psyneuen.2014.01.009. PMID:24636509

*Martire SI, Maniam J, South T, Holmes N, Westbrook RF, Morris MJ (2014) Extended exposure to a palatable cafeteria diet alters gene expression in brain regions implicated in reward, and withdrawal from this diet alters gene expression in brain regions associated with stress.  Behavioural Brain Research 265:132-41. doi: 10.1016/j.bbr.2014.02.027.  PMID:24583192

*Howitt L, Morris MJ, Sandow SL, Murphy TV  (2014) Effect of diet-induced obesity on BK(Ca) function in contraction and dilation of rat isolated middle cerebral artery. Vascular Pharmacology 61(1):10-5. doi: 10.1016/j.vph.2014.02.002. PMID:24576493

*Beilharz JE, Maniam J, Morris MJ  (2014) Short exposure to a diet rich in both fat and sugar or sugar alone impairs place, but not object recognition memory in rats.  Brain, Behavior, and Immunity   37:134-41. PMID:24309633

Zheng TW, O'Brien TJ, Kulikova SP, Reid CA, Morris MJ, Pinault D (2014) Acute effect of carbamazepine on corticothalamic 5-9-Hz and thalamocortical spindle (10-16-Hz) oscillations in the rat.  European Journal of Neuroscience    39(5):788-99. doi: 10.1111/ejn.12441. PMID:24308357

Chen H, Simar D, Morris MJ (2014) Maternal obesity impairs brain glucose metabolism and neural response to hyperglycemia in male rat offspring.  Journal of Neurochemistry 129(2):297-303. PMID:24266932

*Ng SF, Lin RC, Maloney CA, Youngson NA, Owens JA, Morris MJ (2014) Paternal high-fat diet consumption induces common changes in the transcriptomes of retroperitoneal adipose and pancreatic islet tissues in female rat offspring.  FASEB J. 2014 Apr;28 (4):1830-41. doi: 10.1096/fj.13-244046. PMID:24421403

Lin RCY, Ng S-F, Morris MJ (2014) Gene expression in rat models for inter-generational transmission of islet dysfunction and obesity.  Genomics Data 2: 351-353. PMID:26484128

South T, Holmes NM, *Martire SI, Westbrook RF, Morris MJ (2014) Rats eat a cafeteria-style diet to excess but eat smaller amounts and less frequently when tested with chow. PLoS ONE April 2014 9:4 e 93506 doi:10.1371/journal.pone.0093506 PMID:24751610

Samaras K, Morris MJ, Lord RG, Kavurma MM (2014) The effect of bariatric surgery on serum TRAIL and osteoprotegerin levels in obesity complicated by glucose disorders.  Clinical Nutrition ESPEN December 2014 Volume 9, Issue 6, Pages e210–e214  12/2014 DOI: http://dx.doi.org/10.1016/j.clnme.2014.09.004 PMID:

Grayson TH, Chadha PS, Bertrand PP, Chen H, Morris MJ, Senadheera S, Murphy TV, Sandow SL (2013)  Increased caveolae density and caveolin-1 expression accompany impaired NO-mediated vasorelaxation in diet-induced obesity.  Histochem Cell Biol 139(2): 309-21 PMID:23007290

Grant R, Guest J, Bilgin A, Morris MJ, Garg M; Pearce R.  (2013)   Suboptimal Omega-3 Levels in Australian Adolescents.  International Journal of Child Health and Nutrition, http://dx.doi.org/10.6000/1929-4247.2013.02.04.4 PMID:

Youngson NA and Morris MJ (2013) What obesity research tells us about epigenetic mechanisms, Phil. Trans. R. Soc. B 368, (1609):20110337. doi: 10.1098/rstb.2011.0337. PMID:23166398

*Martire S, Holmes N, Westbrook RF, Morris MJ (2013) Altered feeding patterns in rats exposed to a palatable cafeteria diet: Increased snacking and its implications for development of obesity PloS One; 8(4):e60407 PMID:23565243

*Rajia S, Chen H, Morris MJ (2013) Voluntary Post Weaning Exercise Restores Metabolic Homeostasis In Offspring Of Obese Dams Nutrition, Metabolism and Cardiovascular Diseases 23(6): 574-81 PMID:223005126

Bobrovskaya L, Maniam J, Ong LK, Dunkley PR, Morris MJ (2013) Early life stress and post-weaning high fat diet alter tyrosine hydroxylase regulation and AT1 receptor expression in the adrenal gland in a sex dependent manner Neurochemistry Research   38(4):826-33 PMID:23389660

Hansen MJ; Chen H; Jones JE; Langenbach SY; Vlahos R; Gualano RC; Morris MJ; Anderson GP (2013).   The Lung Inflammation and Skeletal Muscle Wasting Induced by Subchronic Cigarette Smoke Exposure Are Not Altered by a High-Fat Diet in Mice. PLoS One, 8, (11), e80471, http://dx.doi.org/10.1371/journal.pone.0080471 PMID:24250397

Ali I, O'Brien P, Kumar G, Zheng T, Jones NC, Pinault D, French C, Morris MJ, Salzberg MR, O'Brien TJ. (2013) Enduring effects of early life stress on firing patterns of hippocampal and thalamocortical neurons in rats: implications for limbic epilepsy. PLoS ONE 8(6): e66962. doi:10.1371/journal.pone.0066962. [I.F. 4.411] PMID:23825595

Elms J, Powell KL, van Raay L, Dedeurwaerdere S; O.Brien TJ, Morris MJ, (2013)  Long-Term Valproate Treatment Increases Brain Neuropeptide Y Expression and Decreases Seizure Expression in a Genetic Rat Model of Absence Epilepsy.  PLoS One, 8(9), pp. e73505 - e73505, http://dx.doi.org/10.1371/journal.pone.0073505 PMID:24039965

Jones NC; Lee HE; Yang M; Rees SM; Morris MJ; O.Brien TJ; Salzberg MR.  (2013).   Repeatedly stressed rats have enhanced vulnerability to amygdala kindling epileptogenesis.   Psychoneuroendocrinology, vol. 38, no. 2, pp. 263 - 270, http://dx.doi.org/10.1016/j.psyneuen.2012.06.005 PMID:22749310

*Bahari H,* Caruso V, Morris MJ (2013) Late Onset Exercise in Female Rat Offspring Ameliorates the Impact of Maternal Obesity, Regardless of Current Diet. Endocrinology, 154(10), 3610 - 3621, http://dx.doi.org/10.1210/en.2013-1059. PMID:23928377

*Caruso V, *Bahari H, Morris MJ (2013) The Beneficial Effects of Early Short-Term Exercise in the Offspring of Obese Mothers are Accompanied by Alterations in the Hypothalamic Gene Expression of Appetite Regulators and FTO (Fat Mass and Obesity Associated) Gene. J Neuroendocrinology 25: 742-752. http://dx.doi.org/10.1111/jne.12053 PMID:23701669

Lecomte V, Youngson N, Maloney CM, Morris MJ (2013) Parental programming: How can we improve study design to discern the molecular mechanisms? BioEssays 35 (9) 787 – 793. http://dx.doi.org/10.1002/bies.201300051 PMID:23881837

Jones NC, Lee HE, Yang M, Rees S, Morris M, O’Brien TJ, Salzberg M. (2013). Repeatedly stressed rats have enhanced vulnerability to amygdala kindling epileptogenesis. Psychoneuroendocrinology 38(2):263-70. [I.F. 5.809] PMID:22749310

South T, Westbrook F, Morris MJ (2012) Neurological and stress related effects of shifting obese rats from a palatable diet to chow and lean rats from chow to a palatable diet Physiol Behaviour 105 (4) 1052-1057 22155008

Zheng TW, O’Brien TJ, Morris MJ, Reid CA, Jovanovska V, O’Brien P, van Raay L, Gandrathi AK, Pinault D. (2012) Rhythmic neuronal activity in S2 somatosensory and insular cortices contribute to the initiation of absence-related spike-and-wave discharges. Epilepsia2012;53:1948-1958. [I.F. 3.961] PMID:23083325

van Raay L, Jovanovska V, Morris MJ, O’Brien TJ. (2012) Focal administration of neuropeptide Y into the S2 somatosensory cortex maximally suppresses absences seizures in a genetic rat model. Epilepsia 53(3):477-484. [I.F. 3.961] PMID:22220638

*Howitt L, Grayson TH, Morris MJ, Sandow SL, Murphy TV (2012) Dietary obesity increases NO and inhibits BKCa-mediated, endothelium-dependent dilation in rat cremaster muscle artery: association with caveolins and caveolae.  Am J Physiol Heart CircPhysiol. 302 (12) H2464-2476 PMID:22492718

Chen H, Simar D, Ting JH, Erkelens JR, Morris MJ (2012) Leucine improves glucose and lipid status in offspring from obese dams, dependent on diet type, but not caloric intake. J Neuroendocrinol. 24(10):1356-1364 PMID:22612562

Simar D, Chen H, Lambert K, Mercier J, Morris MJ (2012) Interaction between maternal obesity and post-natal over-nutrition on skeletal muscle metabolism  Nutr Metab Cardiovasc Disease. 22(3):269-76 Epub Jan 2011; PMID: 21208789 

Dedeurwaerdere S, van Raay L, Morris MJ, Reed RC, Hogan RE, O’Brien TJ. (2011) Fluctuating and constant valproate administration gives equivalent seizure control in rats with genetic and acquired epilepsy. Seizure: European Journal of Epilepsy 2011;20(1):72-79. [I.F. 2.233] PMID:21093310

Haddock RE, Grayson TH, Morris MJ, *Howitt L, Chada PS, Sandow SL (2011) Diet-induced obesity impairs endothelium-derived hyperpolarization via altered potassium channel signaling mechanisms PLoS One Jan 21;6(1):e16423. PMID:21283658

Jiang F, Lim HK, Morris MJ, Prior L, Velkoska E, Wu X & Dusting GJ. (2011) Systemic upregulation of NADPH oxidase in diet-induced obesity in rats. Redox Report 16 (6) 223-229 PMID:22195989

*Howitt L, Sandow SL, Grayson TH, Ellis ZE, Morris MJ, Murphy TV (2011) Differential effects of diet-induced obesity on BKCa {beta}1-subunit expression and function in rat skeletal muscle arterioles and small cerebral arteries. Am J Physiol Heart Circ Physiol.  301(1) H29-40. PMID:21536854

Chen H, Iglesias MA, *Caruso V, Morris MJ (2011) Maternal Cigarette Smoke Exposure Contributes toGlucose Intolerance and Decreased Brain Insulin Action in Mice Offspring Independent of Maternal Diet. PloS One 6(11):e27260. PMID:22076142

*Kumar G, Jones NC, Morris MJ, Rees S, O’Brien TJ, Salzberg MR. (2011) Early life stress enhancement of limbic epileptogenesis: Mechanistic insights. PLoS ONE 2011;6(9): e24033. doi:10.1371/journal.pone.0024033. [I.F. 4.411] PMID:21957442

*Caruso V, Chen H, Morris MJ (2011) Early hypothalamic FTO overexpression in response to maternal obesity - potential contribution to postweaning hyperphagia PloS On 6(9):e25261. Epub 2011 Sep 28 PMID:21880407

Salzberg MR, Morris MJ  (2010) Stress, obesity and metabolic syndrome PMID:

*Velkoska E, Warner F, Cole TJ, Smith I, Morris MJ (2010) Metabolic effects of low dose angiotensin converting enzyme inhibitor in dietary obesity in the rat.  Nutrition, Metabolism & Cardiovascular Disease 20(1):49-55 PMID:19361967

Mellor K, Ritchie RH, Meredith G, Woodman OL, Morris MJ, Delbridge LM. (2010) High-fructose diet elevates myocardial superoxide generation in mice in the absence of cardiac hypertrophy. Nutrition. 26(7-8), 842-848 PMID:19932004

*Maniam J, Morris MJ. (2010) Long-term postpartum anxiety and depression-like behaviour in mother rats subjected to maternal separation are ameliorated by palatable high fat diet. Behavioural Brain Research 208(1):72-79 PMID:19896506

*Maniam J, Morris MJ. (2010) Palatable cafeteria diet ameliorates anxiety and depression-like symptoms following an adverse early environment. Psychoneuroendocrinology 35(5), 717-728 PMID:19939573

Jones NC, Martin S, Megatia I, Hakami T, Salzberg M, Pinault D, Morris M, O'Brien TJ, van den Buuse M. (2010).  Genetic Epilepsy Rat Model Displays Endophenotypes of Psychosis. Neurobiology of Disease; 39(1):116-25. [I.F. 5.403] PMID:20153428

*Senn SM, Kantor S, Poulton I, Morris MJ, Sims NA, O’Brien TJ, and Wark JD (2010) Adverse effects of valproate on bone: Defining a model to investigate the pathophysiology. Epilepsia   51(6), 984-993 PMID:20163440

*Rajia, S, Chen H, Morris MJ (2010) Maternal overnutrition impacts offspring adiposity and brain appetite markers-modulation by post weaning diet. J Neuroendocrinol 22(8), 905-914 PMID:20403085

*Maniam J, Morris MJ. (2010) Voluntary exercise and palatable high fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: role of hippocampus Psychoneuroendocrinology 35(10), 1553-1564 PMID:20594764

Chadha PS, Haddock RE, *Howitt L, Morris MJ, Murphy TV, Grayson TH, Sandow SL (2010). Obesity upregulates intermediate conductance calcium-activated potassium channels and myoendothelial gap junctions to maintain endothelial vasodilator function. J Pharmacol Exp Therapeutics 335(2), 284-293 PMID:20671071

Guest J, Bilgin A, Pearce R, Baines S, Zeuschner C, Le Rossignol-Grant C, Morris, MJ, Grant R (2010) Evidence for under nutrition in adolescent females using routine dieting practices. Asia Pacific J Clin Nutrition 19(4), 526-533 21147714

*Ng, SF, Lin R CY Laybutt, DR, Barres R, Owens, JA, Morris MJ (2010). Chronic high fat diet in fathers programs beta cell dysfunction in female rat offspring. Nature 467(7318), 963-966 PMID:20962845

*Zheng T, Clarke AL, Morris MJ, Reid CA, Petrou S, O’Brien TJ (2009) Oxcarbazepine not its active metabolite potentiates GABA-A receptor activation and aggravates absence seizures Epilepsia 50(1), 83-87 PMID:

Morris, MJ, Chen H (2009) Established maternal obesity in the rat reprograms hypothalamic appetite regulators and leptin signaling at birth. Int J Obesity, 33(1) 115-122.  PMID:18982008

van Raay L, Morris MJ, Reed R, O’Brien TJ, Dedeurwaerdere S. (2009) A novel system allowing long-term simultaneous video-electroencephalography recording, drug infusion and blood sampling in rats. Journal of Neuroscience Methods, 179(2):184-190. [I.F. 2.243] PMID:19428526

Chen H & Morris MJ (2009) Differential responses of orexigenic neuropeptides to fasting in offspring of obese mothers. Obesity (Silver Springs) 17(7), 1356-1362 PMID:19282828

Shiraev T, Chen H, Morris MJ (2009) Differential effects of restricted versus unlimited high-fat feeding in rats on fat mass, plasma hormones and brain appetite regulators. J Neuroendocrinology 21(7), 602-609 PMID:19490368

Jones NC, Kumar G, O’Brien TJ, Morris MJ, Rees SM, Salzberg MR (2009) Anxiolytic effects of rapid amygdala kindling, and the influence of early life experience in rats. Behavioural Brain Research 203:81-87. [I.F. 3.171] PMID:19397932

Chen H, Simar D, Morris MJ (2009) Hypothalamic circuitry is programmed by maternal obesity: interaction with postnatal nutritional environment.  PLoS One Jul 16;4(7):e6259 PMID:19606226

Morris MJ, Chen H, Watts R, Shulkes A, Cameron-Smith D. (2008) Brain neuropeptide Y and CCK and peripheral adipokine receptors: temporal response in obesity induced by palatable diet.  Int J Obesity (Lond) 32(2), 249-258 PMID:17768423

Jones NC, Salzberg MR, Kumar G, Couper A, Morris MJ, O'Brien TJ. (2008). Elevated anxiety and depressive-like behavior in a rat model of genetic generalized epilepsy suggesting common causation. Experimental Neurology 209(1):254-60. [I.F. 4.669] PMID:18022621

Chen H, Simar D, Lambert K, Mercier J, Morris MJ (2008) Maternal and Postnatal Overnutrition Differentially Impact Appetite Regulators and Fuel Metabolism.  Endocrinology 149(11):5348-5356. PMID:18635655

Siebel AL, Mibus A, de Blasio MJ, Westcott KT, Morris MJ, Prior L, Owens JA, Wlodek ME. (2008) Improved lactational nutrition and postnatal growth ameliorates impairment of glucose tolerance by uteroplacental insufficiency in male rat offspring.  Endocrinology149(6):3067-3076 PMID:18339706

*Velkoska E, Cole TJ, Dean RG, Burrell LM, Morris MJ (2008) Early undernutrition leads to longlasting reductions in body weight and adiposity whereas increased intake increases cardiac fibrosis in male rats.  J  Nutrition, 138(9); 1622- 1627 (selected as editor’s pick of the month) PMID:18716160

Chen H, Hansen MJ, Jones JE, Vlahos R, Anderson GP, Morris MJ (2008) Long-term cigarette smoke exposure increases uncoupling protein expression but reduces energy intake.  Brain Research, 1228; 81-88 PMID:18619427

Prior L, *Velkoska E, Watts R, Cameron-Smith D, Morris MJ (2008) Under-nutrition during suckling in rats elevates plasma adiponectin and its receptor in skeletal muscle regardless of diet composition - a protective effect?  Int J Obesity, 32; 1585-1594 PMID:18725894

Mitchell PB and Morris MJ. (2007) Depression and anxiety with rimonabant.  Lancet 370 (9600), 1671-1672 [invited commentary] PMID:18022023

Chen H, Hansen MJ, Jones JE, Vlahos R, Anderson GP, Morris MJ (2007) Detrimental metabolic effects of combining long term cigarette smoke exposure and high fat diet in mice Am J Physiol Endocrinol Metab 293(6), E1564-E1571 PMID:17940214

Chen H & Morris MJ (2007) Maternal smoking – a contributor to the obesity epidemic? Obesity Research & Clinical Practice 1, 155-163 PMID:24351541

*Kumar G, *Coupar A, O’Brien TJ, Salzberg MJ, Jones NC, Rees S, Morris MJ (2007) The acceleration of amygdala kindling epileptogenesis by chronic low-dose corticosterone involves both mineralocorticoid and glucocorticoid receptors.   Psychoneuroendocrinology 32(7):834-42 PMID:17614213

Salzberg M, *Kumar G, *Supit L, Jones NC, Morris MJ, Rees S, O’Brien TJ (2007) Early postnatal stress confers enduring vulnerability to limbic epileptogenesis.  Epilepsia 48 (11) 2079-2085 PMID:17999745

Morris MJ, Gannan E, Stroud LM, Beck-Sickinger A, O’Brien TJ (2007) Neuropeptide Y suppresses absence seizures in a genetic rat model primarily through effects on Y2 receptors. Eur J Neuroscience, 25(4), 1136-1143 PMID:17331209

*Senn SM, Kantor S, Andrikopoulos S, Proietto J, O’Brien T, Morris MJ, Wark JD.  (2007) In vivo quantification of fat content in mice using the Hologic QDR 4500A densitometer. Obesity Research & Clinical Practice 1(1), 1-78 PMID:24351433

*Chen H, Hansen MJ, Jones JE, Vlahos R, Bozinovski S, Anderson GP, Morris MJ. (2007) Regulation of hypothalamic NPY by diet and smoking. Peptides 28(2), 384-389 PMID:17207894

Fam BC, Morris MJ, Hansen MJ, Kebede M, Andrikopoulos S, Thorburn AW. (2007) Modulation of leptin sensitivity and energy balance in a rat model of diet-induced obesity.  Diabetes Obesity & Metabolism 9(6), 840-852 PMID:17924866

Liu L, *Zheng T, Morris MJ, *Wallengren C, Clark AL, Reid CA, Petrou S, O'Brien TJ. (2006) The mechanism of carbamazepine aggravation of absence seizures. J Pharmacol Exp Ther, 319, 790-798 PMID:16895979

*Chen H, Kent S & Morris MJ. (2006) Is the CCK2 receptor essential for normal regulation of body weight and adiposity? Eur J Neuroscience 24(5), 1427-1433 PMID:16965546

*Chen H, Hansen MJ, Jones JE, Vlahos R, Bozinovski,S, Anderson GA & Morris MJ (2006) Cigarette smoke exposure reprograms the hypothalamic neuropeptide Y axis to promote weight loss.   American J Respiratory and Critical Care Medicine. 173(11), 1248-1254 extensive media coverage, including QUIT campaign website PMID:16531608

Langan- Fox J, Morris MJ.  (2005) Ageing and stress: ergonomic issues in employing the older worker. Human Factors, Asian J Ergonomics   6, 1-7 PMID:

Morris MJ, *Velkoska E, Cole TJ. (2005) Central and peripheral contributions to obesity associated hypertension: impact of early overnourishment.  Exp. Physiol 90(5):697-702 16105938

Lohman R-J, Liu L, Morris M & O’Brien TJ.  (2005) Validation of a method for localised microinjection of drugs into thalamic subregions in rats for pharmacological epilepsy studies. J Neuroscience Methods, 146(2), 191-197 PMID:160545009

*Taher TR, Salzberg M, Morris MJ, Rees S, O’Brien TJ. (2005) Chronic low-dose corticosterone supplementation enhances acquired epileptogenesis in the rat amygdala kindling model of TLE.  Neuropsychopharmacology 30(9), 1610-1616 PMID:15770235

*Bedoui S, *Velkoska E, Bozinovski S, Jones JE, Anderson GP, Morris MJ. (2005)  TNF-alpha production by macrophages and monocytes is preserved in diet-induced obesity J Inflammation (Lond), 2(1):2. PMID:

*Wallengren C, Li S, Morris MJ, Jupp B, O’Brien TJ. (2005) Aggravation of absence seizures by carbamazepine in a genetic rat model does not induce neuronal c-Fos activation Clinical Neuropharmacology, 28(2), 60-65. PMID:15795547

*Hansen MJ, Schiöth HB, Morris MJ. (2005) Feeding responses to a melanocortin agonist and antagonist in obesity induced by a palatable high-fat diet Brain Research, 1039(1-2), 137-145 PMID:15781055

*Velkoska E, Cole TJ & Morris MJ (2005) Early dietary intervention: long term effects on blood pressure, brain neuropeptide Y and adiposity markers. Am J Physiology, Endocrinol Metab 288 (6), E1236-E1243 PMID:15644456

*Tan HM, Gundlach A & Morris MJ. (2005) Exaggerated feeding response to central galanin-like peptide administration in diet-induced obese rats. Neuropeptides, 39(3), 333-336 PMID:15944031

*Stroud L, Jupp, B, *Wallengren C, O’Brien T, Morris MJ. (2005) Neuropeptide Y suppresses absence seizures in a genetic rat model. Brain Research, 1033(2), 151-156 PMID:15694919

Chen H, Vlahos R, Jones J, Anderson GP & Morris MJ (2005) The effect of short term cigarette smoke exposure on body weight, appetite and brain neuropeptide Y in mice Neuropsychopharmacology 30(4), 713-719 PMID:15508020

Van den Buuse M, Morris M, Chavez C, Martin S, Wang J (2004) Effect of adrenalectomy and corticosterone replacement on prepulse inhibition and locomotor activity in mice. Br J Pharmacol. 142 (3), 543-550 PMID:15148266

*Lax CJ, Domenighetti AA, Pavia JM, Di Nicolantonio, Curl CL, Morris MJ, Delbridge LMD. (2004) Transitory reduction in angiotensin AT2 receptor expression level in post-infarct remodelling in rat myocardium. Clin Exp Pharmacol Physiol  31 (8), 512-517. PMID:15298543

*Morris MJ, Tortelli CF, Hart DP, Delbridge LMD. (2004) Vascular and brain neuropeptide Y in banded and spontaneously hypertensive rats Peptides 25 (8), 1313-1319. PMID:15350699

Hastings JA, Morris MJ, Lambert G, Lambert E and Esler M. (2004) NPY and NPY Y1 receptor effects on noradrenaline overflow from the rat brain in vitro.  Regulatory Peptides 120(1-3), 107-112. PMID:15177927

Morris MJ and Pavia JM (2004) Increased endogenous noradrenaline and neuropeptide Y release from the hypothalamus of streptozotocin diabetic rats.  Brain Res 1006 (1), 100-106. PMID:15047028

Eikelis N, Lambert G, Wiesner G, Kaye D, Schlaich M, Morris M, Hastings J, Socratous F and Esler M.  (2004) Extra-adipocyte leptin release in human obesity and its relation to sympathoadrenal function.  Am J Physiol Endocrinol Metab 286 (5) E744-752. PMID:14722031

*Lee J, Albiston AL, Allen AM, Mendelsohn FA, Ping SE, Barrett GL, Murphy M, Morris MJ, McDowall SG, Chai SY (2004) Effect of I.C.V. injection of AT4 receptor ligands, NLE1-angiotensin IV and LVV-hemorphin 7, on spatial learning in rats. Neuroscience 124 (2), 341-349. PMID:14980384

 *Hansen MJ, Jovanovska V and Morris MJ (2004)   Adaptive responses in hypothalamic neuropeptide Y in the face of prolonged high fat feeding in the rat.   J Neurochem 88(4), 909-916. PMID:14756812

*Velkoska E, Morris MJ, Burns P, Weisinger RW (2003) Leptin reduces food intake but does not alter weight regain following food deprivation in the rat.   Int J Obesity 27(1), 48-54. PMID:12532153

Estrada KM, Pompolo S, Morris MJ Tilbrook AJ and Clarke IJ (2003) Neuropeptide Y (NPY) delays the oestrogen-induced luteinizing hormone (LH) surge in the ovariectomized ewe: further evidence that NPY has a predominant negative effect on LH secretion in the ewe.  J Neuroendocrinology 15(11), 1011-1020. PMID:14622430

*Lee J, Chai S-Y, Morris MJ, Mendelsohn FAO, Allen AM (2003) Effect of fimbria-fornix lesion on 125I-angiotesnin IV (Ang IV) binding in the guinea pig hippocampus.  Brain Res 979(1-2), 7-14. PMID:12850565

Fitzgerald PB, Scaffidi A, Morris MJ, de Castella AR, Kulkarni J.  (2003) The relationship of changes in leptin, neuropeptide Y and reproductive hormones to antipsychotic induced weight gain.  Hum Psychopharmacol. 18(7), 551-557. PMID:14533137

*O’Shea M, Hansen MJ, Tatemoto K, Morris MJ (2003) Inhibitory effect of apelin-12 on nocturnal food intake in the rat. Nut Neurosci6(3), 163-167. PMID:12793520

Pavia JM, Schioth H, Morris MJ (2003) Role of MC4 receptors in the depressor and bradycardic effects of -MSH in the nucleus tractus solitarii of the rat.  Neuroreport 14(5), 703-707. PMID:12692467

Aggarwal A, Esler MD, Morris MJ, Lambert G, Kaye DM (2003) Regional sympathetic effects of low-dose clonidine in heart failure.  Hypertension 41(3), 553-537 PMID:12623958

Arnould JPY, Morris MJ, Rawlins, DR, Boyd IL. (2002) Variation in plasma leptin levels in response to fasting in Antarctic fur seals (Artocephalus gazella). J Comp Physiol B 172(1), 27-34. PMID:11824401

*Chaffer C & Morris MJ. (2002) The feeding response to melanin concentrating hormone is attenuated by Y1 receptor blockade.  Endocrinology 143(1), 191-197. PMID:11751609

Hastings J, Wiesner G, Lambert G, Morris MJ, Head, G, Esler M. (2002) Influence of leptin on neurotransmitter overflow from the rat brain in vitro.  Regulatory Peptides 103(2-3), 67-74. PMID:11786145

Keast JR, Gleeson RJ, Shulkes A, Morris MJ. (2002) Maturational and maintenance effects of testosterone on terminal axon density and neuropeptide expression in the rat vas deferens. Neuroscience 112(2), 391-398. PMID:12044456

Hansen MJ and Morris MJ. (2002) Evidence for an interaction between neuropeptide Y and the melanocortin-4 receptor on feeding in the rat.  Neuropharmacology 42(6), 792-797. PMID:12015205

*Gozali M, Pavia, JM, Morris, MJ (2002) Involvement of neuropeptide Y in glucose sensing in the dorsal hypothalamus of streptozotocin diabetic rats- in vitro and in vivo studies of transmitter release Diabetologia 45(9), 1332-1339. PMID:12242467

Turner A, Rivalland ETA, Clarke IJ, Lambert GW, Morris MJ, Tilbrook AJ (2002) Noradrenaline, but not neuropeptide Y, is elevated in cerebrospinal fluid from the third ventricle following audiovisual stress in gonadectomised rams and ewes.  Neuroendocrinology 76(6), 373-380. PMID:12566945

*Lee J, Chai SY, Mendelsohn FA, Morris MJ & Allen AM. (2001) Potentiation of cholinergic transmission in the rat hippocampus by angiotensin IV and LVV-hemorphin-7. Neuropharmacology, 40(4): 618-623. PMID:11249971

*Hansen MJ, Ball, M J & Morris MJ. (2001) Enhanced inhibitory feeding response to alpha-melanocyte stimulating hormone in the diet-induced obese rat. Brain Res, 892(1): 130-137. PMID:11172758

*Hastings, JA, McClure-Sharp JM & Morris MJ. (2001) NPY Y1 receptors exert opposite effects on corticotropin releasing factor and noradrenaline overflow from the rat hypothalamus in vitro. Brain Res, 890(1): 32-37. PMID:11164766

Morris MJ. & Nguyen T. (2001) Does neuropeptide Y contribute to the anorectic action of amylin? Peptides, 22(3): 541-546. PMID:11287112

Ainslie DA, Morris MJ, Wittert, G. et. al. (2001) Estrogen deficiency causes central leptin insensitivity and increased hypothalamic neuropeptide Y. Int J Obesity, 25(11), 1680-1688. PMID:11753591

Furness JB, Koopmans HS, Robbins HL, Clerc N, Tobin JM, Morris MJ. (2001) Effects of vagal and splanchnic section on weight, serum leptin and hypothalamic neuropeptide Y in rat. Autonomic Neuroscience, 92(1-2), 28-36. PMID:11570701

Morris, MJ & Pavia, JM (1998) Stimulation of neuropeptide Y overflow in the rat paraventricular nucleus by corticotropin-releasing factor. J Neurochem, 71(4): 1519-24. PMID:9751185

Warnes, KE, Morris MJ, Symonds ME, Phillips, ID, Clarke, IJ, Owens JA & McMillen IC. (1998) Effects of increasing gestation, cortisol and maternal undernutrition on hypothalamic neuropeptide Y expression in the sheep fetus. J Neuroendocrinol, 10(1): 51-7. PMID:9510058

*Hastings JA, McClure-Sharp JM & Morris MJ. (1998) In vitro studies of endogenous noradrenaline and NPY overflow from the rat hypothalamus during maturation and ageing. Naunyn Schmiedebergs Arch Pharmacol, 357(3): 218-224. PMID:9550291

Symeonides SN, Morris MJ, Bournat JC & Allen, JM. (1998) Leptin regulation of expression of neuropeptide Y and its receptor. Biochem Soc Trans, 26(3): S203. PMID:97655922

*Lee J & Morris MJ. (1998) Modulation of neuropeptide Y overflow by leptin in the rat hypothalamus, cerebral cortex and medulla. Neuroreport, 9(7): 1575-1580. PMID:9631469

Morris MJ, Tortelli, CF, Filippis A & Proietto J. (1998) Reduced BAT function as a mechanism for obesity in the hypophagic, neuropeptide Y deficient monosodium glutamate-treated rat. Regul Pept, 75-76: 441-447. PMID:9802441

Morris MJ, Hastings JA & Pavia JM. (1997) Central interactions between noradrenaline and neuropeptide Y in the rat: implications for blood pressure control. Clin Exp Hypertens, 19(5-6): 619-30. PMID:9247743

Morris MJ & Pavia, JM. (1997) Lack of effect of age on the cardiovascular response to neuropeptide Y injection in the rat nucleus tractus solitarius. Clin Exp Pharmacol Physiol, 24(2): 162-5. PMID:9075590

*Hastings JA, Pavia JM, Morris MJ. (1997) Neuropeptide Y and [Leu31,Pro34]neuropeptide Y potentiate potassium-induced noradrenaline release in the paraventricular nucleus of the aged rat. Brain Res. 1997 750(1-2), 301-304. PMID:9089556

Ulman LG, Potter EK, McCloskey DI & Morris MJ. (1997) Post-exercise depression of baroreflex slowing of the heart in humans. Clin Physiol, 17(3): 299-309. PMID:9171970

Morris MJ, Cox HS, Lambert GW, Kaye DM, Jennings GL, Meredith IT & Esler MD. (1997) Region-specific neuropeptide Y overflows at rest and during sympathetic activation in humans. Hypertension, 29(1): 137-43 PMID:9039093

*Hastings, JA, Pavia, JM & Morris MJ. (1996) Altered in vivo catecholamine release in the hypothalamic paraventricular nucleus of the aged rat. Naunyn Schmiedebergs Arch Pharmacol, 353(2): 161-7 PMID:8717156

*Pavia JM, Hastings, JA & Morris MJ. (1995) Neuropeptide Y potentiation of potassium-induced noradrenaline release in the hypothalamic paraventricular nucleus of the rat in vivo. Brain Res, 690(1): 108-11. PMID:7496795

Esler MD, Turner AG, Kaye, DM, Thompson, JM, Kingwell BA, Morris M, Lambert, GW, Jennings GL, Cox HS & Seals, DR (1995) Aging effects on human sympathetic neuronal function. Am J Physiol, 268: R278-85. PMID:

Morris MJ, Hastings JA & Pavia JM. (1994) Catecholamine release in the rat hypothalamic paraventricular nucleus in response to haemorrhage, desipramine and potassium. Brain Res, 665(1): 5-12. PMID:7882018

Pavia JM & Morris MJ. (1994) Age-related changes in neuropeptide Y content in brain and peripheral tissues of spontaneously hypertensive rats. Clin Exp Pharmacol Physiol, 21(4): 335-8 PMID:7923902

Whitworth JA, Williamson PM, Brown MA & Morris MJ. (1994) Neuropeptide Y in cortisol-induced hypertension in male volunteers. Clin Exp Pharmacol Physiol, 21(5): 435-8. PMID:7955553

Kaye DM, Lambert GW, Lefkovits J, Morris M, Jennings G & Esler, M. D. (1994) Neurochemical evidence of cardiac sympathetic activation and increased central nervous system norepinephrine turnover in severe congestive heart failure. J Am Coll Cardiol, 23(3): 570-8. PMID:8113536

David-Dufilho M, Pernollet MG, Morris M, Astarie-Dekequer C & Devynck MA. (1994) Erythrocyte Ca2+ handling in the spontaneously hypertensive rat, effect of vanadate ions. Life Sci, 54(4): 267-74 PMID:8289587

Westerman, RA, Carr, RW, Delaney, CA, Morris, MJ & Roberts, RG. (1993) The role of skin nociceptive afferent nerves in blister healing. Clin Exp Neurol, 30: 39-60. PMID:7712628

Clarke, I, Jessop D, Millar R, Morris M, Bloom S, Lightman S, Coen CW, Lew R & Smith I. (1993) Many peptides that are present in the external zone of the median eminence are not secreted into the hypophysial portal blood of sheep. Neuroendocrinology, 57(5): 765-75. PMID:7692337

Morris M J, Dufilho, MD & Devynck MA. (1992) In vivo and in vitro effects of isradipine on cytosolic Ca2+ concentration in erythrocytes from spontaneously hypertensive rats. Am J Hypertens, 5(12): 887-91. PMID:1285938

Tonkin AL, Wing LM, Morris MJ & Kapoor V. (1991) Afferent baroreflex dysfunction and age-related orthostatic hypotension. Clin Sci (Colch), 81(4): 531-38. PMID:1657501

Minson RB, McRitchie RJ, Morris MJ & Chalmers JP. (1990) Effects of neuropeptide Y on cardiac performance and renal blood flow in conscious normotensive and renal hypertensive rabbits. Clin Exp Hypertens A, 12(2): 267-84. PMID:2347098

Drolet G, Aslanian V, Minson J, Morris M & Chalmers J. (1990) Differences in the central hypotensive actions of alpha-methyldopa and clonidine in the spontaneously hypertensive rat: contribution of neurons arising from the B3 and the C1 areas of the rostral ventrolateral medulla. J Cardiovasc Pharmacol, 15(1): 118-23. PMID:1688968

Tonkin AL, Wing LM, Russell AE, West MJ, Bune, AJ, Morris MJ, Cain MD & Chalmers J. (1990) Diltiazem and atenolol in essential hypertension: additivity of effects on blood pressure and cardiac conduction with combination therapy. J Hypertens, 8(11): 1015-9 PMID:1963183

Minson JB, Chalmers J, Drolet G, Kapoor V, Llewellyn-Smith I, Mills E, Morris, MJ & Pilowsky P. (1989) Central serotenergic mechanisms in cardiovascular regulation. Cardiovascular Drugs and Therapy, 4(1): 27-32. PMID:2285647

Russell, AE, Cain, MD, Kapoor, V, Morris, MJ & Chalmers, JP. (1989) Neuropeptide Y-like immunoreactivity of plasma during hypoglycaemia in man. J Auton Nerv Syst, 26(1): 85-88. PMID:2708787

Chalmers J, Morris M, Kapoor V, Cain, M, Elliott J, Russell A, Pilowsky P, Minson J, West M & Wing L. (1989) Neuropeptide Y in the sympathetic control of blood pressure in hypertensive subjects. Clin Exp Hypertens A, 11 (S1): 59-66. PMID:2743605

Morris, M., Devynck, M. A., Pernollet, M. G. & Meyer, P. (1988) Variations in the plasma concentrations of atrial natriuretic factor and endogenous digitalis compounds during acute volume expansion in the conscious rat. Arch Mal Coeur Vaiss, 81 Spec No: 105-8. PMID:2847669

Morilak, D. A., Morris, M. & Chalmers, J. (1988) Release of substance P in the nucleus tractus solitarius measured by in vivo microdialysis: response to stimulation of the aortic depressor nerves in rabbit. Neurosci Lett, 94(1-2): 131-7. PMID:2468813

Chalmers, J. P., Minson, J. B., Pilowsky, P. M., Kapoor, V., Mills, E., Morris, M. J. & West, M. J. (1988) Pressor systems from ventrolateral medulla: Epinephrine- and serotonin-containing neurons. In Progress in Catechol Res. Part B: Central Aspects. 1988;291-295. PMID:

Morris, MJ, David-Dufilho M & Devynck, MA. (1988) Red blood cell ionized calcium concentration in spontaneous hypertension: modulation in vivo by the calcium antagonist PN 200.110. Clin Exp Pharmacol Physiol, 15(4): 257-60. PMID:2978740

Wing LM, Chalmers JP, West MJ, Russell AE, Morris MJ, Cain, MD, Bune AJ & Southgate DO. (1988) Enalapril and atenolol in essential hypertension: attenuation of hypotensive effects in combination. Clin Exp Hypertens A, 10(1): 119-33. PMID:2832102

Wing LM, Chalmers, JP, West, MJ, Bune AJ, Russell, AE, Elliott, JM & Morris, MJ. (1987) Treatment of hypertension with enalapril and hydrochlorothiazide or enalapril and atenolol: contrasts in hypotensive interactions. J Hypertens Suppl, 5(5): S603-6. PMID:2832575

Pilowsky, PM, Morris, M. J., Minson, J. B., West, M. J., Chalmers, J. P., Willoughby, J. O. & Blessing, W. W. (1987) Inhibition of vasodepressor neurons in the caudal ventrolateral medulla of the rabbit increases both arterial pressure and the release of neuropeptide Y-like immunoreactivity from the spinal cord. Brain Res, 420(2): 380-4. PMID:3676770

Chalmers J, Kapoor V, Mills E, Minson J, Morris M, Pilowsky P & West, M. (1987) Do pressor neurons in the ventrolateral medulla release amines and neuropeptides? Can J Physiol Pharmacol, 65(8): 1598-604. PMID:3690392

Morris, M., Cain, M. & Chalmers, J. (1987) Complementary changes in plasma atrial natriuretic peptide and antidiuretic hormone concentrations in response to volume expansion and haemorrhage: studies in conscious normotensive and spontaneously hypertensive rats. Clin Exp Pharmacol Physiol, 14(4): 283-9. PMID:2959421

Morris, M., Cain, M., Russell, A., Elliott, J. & Chalmers, J. (1987) Direct radioimmunoassay of human plasma atrial natriuretic peptide in various normal and pathophysiological states: increase in renal and cardiac failure during exercise. Clin Exp Hypertens A, 9(4): 703-18. PMID:2957125

Morris MJ, Pilowsky PM, Minson JB, West MJ & Chalmers JP. (1987) Microinjection of kainic acid into the rostral ventrolateral medulla causes hypertension and release of neuropeptide Y-like immunoreactivity from rabbit spinal cord. Clin Exp Pharmacol Physiol, 14(2): 127-32. PMID:3608244

Morris, M., Kapoor, V. & Chalmers, J. (1987) Plasma neuropeptide Y concentration is increased after hemorrhage in conscious rats: relative contributions of sympathetic nerves and the adrenal medulla. J Cardiovasc Pharmacol, 9(5): 541-5. PMID:2439834

Morris, M. J., Pilowsky, P. M., Cain, M. D. & Chalmers, J. P. (1987) Plasma atrial natriuretic peptide is increased during atrial pacing in conscious rabbits. Clin Exp Pharmacol Physiol, 14(1): 59-63. PMID:2955987

Pilowsky, P. M., Morris, M. J., Kapoor, V., West, M. J. & Chalmers, J. P. (1986) Role of renal nerve activity, plasma catecholamines and plasma vasopressin in cardiovascular responses to intracisternal neurotoxins in the rabbit. J Auton Nerv Syst, 17(2): 109-20. PMID:3097113

Chalmers, J. P., Wing, L. M., West, M. J., Bune, A. J., Elliott, J. M., Morris, M. J., Cain, M. D., Graham, J. R. & Southgate, D. O. (1986) Effects of enalapril and hydrochlorothiazide on blood pressure, renin-angiotensin system, and atrial natriuretic factor in essential hypertension: a double blind factorial cross-over study. Aust N Z J Med, 16(4): 475-80. PMID:3026294

Morris, M. J., Russell, A. E., Kapoor, V., Cain, M. D., Elliott, J. M., West,M. J., Wing, L. M. & Chalmers, J. P. (1986) Increases in plasma neuropeptide Y concentrations during sympathetic activation in man. J Auton Nerv Syst, 17(2): 143-9. PMID:3782722

Howe, P. R., Rogers, P. F., Morris, M. J., Chalmers, J. P. & Smith, R. M. (1986) Plasma catecholamines and neuropeptide-Y as indices of sympathetic nerve activity in normotensive and stroke-prone spontaneously hypertensive rats. J Cardiovasc Pharmacol, 8(6): 1113-21. PMID:2434735

Morris, M. J., Elliott, J. M., Cain, M. D., Kapoor, V., West, M. J. & Chalmers, J. P. (1986) Plasma neuropeptide Y levels rise in patients undergoing exercise tests for the investigation of chest pain. Clin Exp Pharmacol Physiol, 13(5): 437-40. PMID:3755659

Macrae, I. M., Minson, J. B., Kapoor, V., Morris, M. J. & Chalmers, J. P. (1986) Midline B3 serotonin nerves in rat medulla are involved in hypotensive effect of methyldopa. J Cardiovasc Pharmacol, 8(2): 381-5. PMID:2422478

Woodcock, E. A., Morris, M. J., McLeod, J. K. & Johnston, C. I. (1985) Specific increase in renal alpha 1-adrenergic receptors following unilateral renal denervation. J Recept Res, 5(2-3): 133-46 PMID:2993602

Harvey, A. R., Minson, J. B., Morris, M. J. & Chalmers, J. P. (1984) Embryonic hypothalamic tissue transplanted to the IVth ventricle of newborn Brattleboro rats. Neurosci Lett, 52(3): 269-74. PMID:6395046

Morris, M. J. & Woodcock, E. A. (1983) Peripheral adrenoceptors after sino-aortic denervation. Clin Exp Pharmacol Physiol, 10(3): 341-4. PMID:6313266

Morris, M. J. & Woodcock, E. A. (1983) Postnatal development of rat alpha- and beta-adrenergic receptors: A comparison between tissues. Int J Devel Neuroscience, 1(1): 35-42. PMID:24875604

Morris, M.J. & Woodcock E. A. (1982) Central α-Adrenoceptors and blood pressure regulation in the rat. Clinical and Experimental Pharmacology and Physiology Volume 9, Issue 3, pages 303–307. PMID:6291826

Morris, M. J., Elghozi, J. L., Dausse, J. P. & Meyer, P. (1981) alpha 1- and alpha 2-adrenoceptors in rat cerebral cortex: effect of frontal lobotomy. Naunyn Schmiedebergs Arch Pharmacol, 316(1): 42-44. PMID:6268996

Morris MJ, Devynck MA, Woodcock EA, Johnston CI, Meyer P (1981) Specific changes in hypothalamic alpha-adrenoceptors in young spontaneously hypertensive rats. Hypertension 3(5):516-520. PMID:6271667

Morris Mj, Elghozi Jl, Dausse JP, Meyer P (1980) Effect of surgical denervation on alpha-1-adrenoceptors and alpha-2-adrenoceptors in rat cerebral-cortex  Clinical and Experimental Pharmacology and Physiology 7(6):659-659. 

Morris, MJ, Dausse, J. P., Devynck, M. A. & Meyer, P. (1980) Ontogeny of alpha 1 and alpha 2-adrenoceptors in rat brain. Brain Res, 190(1): 268-71. PMID:6247010

Wahlqvist, M. L., Morris, M. J., Littlejohn, G. O., Bond, A. & Jackson, R. V. (1979) The effects of dietary fibre on glucose tolerance in healthy males. Aust N Z J Med, 9(2): 154-8. PMID:287457

Blair-West, J. R., Brook, A. H., Gibson, A., Morris, M. & Pullan, P. T. (1979) Renin, antidiuretic hormone and the kidney in water restriction and rehydration. J Physiol, 294(1): 181-93. PMID:512941

Peer-reviewed Review Articles and Editorials

Bortolasci, Morris et al (2020) Minocycline for the treatment of mental health and neurological conditions: A systematic review protocol. BMJ Open 2019-035080

Finney CA, Shvetcov A, Westbrook RF, Jones NM, Morris MJ (2019) The role of hippocampal estradiol in synaptic plasticity and memory: A systematic review. Frontiers in Neuroendocrinology PMID: 31843506

Kendig MD, Morris MJ (2019) Fizzing out: No effect of acute carbohydrate consumption on mood. Neuroscience and Biobehavioral Reviews 104:56-57 PMID: 31265871

Kendig MD, Morris MJ (2019) Reviewing the effects of dietary salt on cognition: mechanisms and future directions. ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION 28(1):6-14  PMID: 30896408 

*Leigh S-J, Lee F, Morris MJ (2018) Hyperpalatability and the Generation of Obesity: Roles of Environment, Stress Exposure and Individual Differences Current Obesity Reports 7(1):6-18 PMID:29435959

*Leigh SJ, Morris MJ (2018) The role of reward circuitry and food addiction in the obesity epidemic: an update Biol Psychology 131:31-42  doi: 10.1016/j.biopsycho.2016.12.013 PMID:28011401

Youngson NA, Morris MJ, Ballard JWO (2017) The mechanisms mediating the antiepileptic effects of the ketogenic diet, and potential opportunities for improvement with metabolism-altering drugs Seizure 52, 15-19. PMID:28941398

Walker CD et al (2017) Chronic early life stress induced by limited bedding and nesting (LBN) material in rodents: critical considerations of methodology, outcomes and translational potential Stress 20(5):421-448. PMID:28617197

Reichelt A, Westbrook RF, Morris MJ (2017) Impact of diet on learning, memory and cognition Frontiers in Behavioral Neuroscience – editorial 11-96 doi:10.3389/fnbeh.2017.00096 PMID:

Kaakoush NO, Morris MJ (2017) More flavor for flavonoid-based interventions? Trends Molecular Medicine 23(4) 293-295, http://dx.doi.org/10.1016/j.molmed.2017.02.008 PMID:28318994

Kaakoush NO, Morris MJ. (2016) The oesophageal microbiome: an unexplored link in obesity-associated oesophageal adenocarcinoma. FEMS Microbiol Ecol. 2016;92(10):pii:fiw161. PMID:27465078

Morris MJ, Le V, Maniam J. (2016) The impact of poor diet and early life stress on memory status. Current Opinion in Behavioral Sciences, 9, 144-151 PMID:

Dickinson H, Moss TJ, Gatford KL, Moritz KM, Akison L, Fullston T, Hryciw DH, Maloney CA, Morris MJ, Wooldridge AL, Schjenken JE, Robertson SA, Waddell BJ, Mark PJ, Wyrwoll CS, Ellery SJ, Thornburg KL, Muhlhausler BS, Morrison JL (2016) A review of fundamental principles for animal models of DOHaD research: An Australian perspective. J Devel Origin Disease 7(5) 449-472.PMID:27689313

Morris (2015) Diet on the Brain. The effect of food on cognition. Independence. (Journal of the Association of Heads of Independent Schools of Australia)  40(1):58-63 PMID:

Reichelt A, Westbrook RF, Morris MJ (2015) Integration of reward signalling and appetite regulating peptide systems in the control of food-cue responses Brit J Pharmacology 172(22):5225-38 doi: 10.1111/bph.13321 PMID:26403657

Beilharz JE, Maniam J, Morris MJ (2015) Diet-Induced Cognitive Deficits: The Role of Fat and Sugar, Potential Mechanisms and Nutritional Interventions. Nutrients 7(8): 6719-38 PMID:27274972

Morris MJ, Beilharz JE, Maniam J, Reichelt AC, Westbrook RF. (2015) Why is obesity such a problem in the 21st century? The intersection of palatable food, cues and reward pathways, stress, and cognition.  Neurosci Biobehav Rev. 2015 Nov; 58:36-45. pii: S0149-7634(14)00333-9. doi: 10.1016/j.neubiorev.2014.12.02. Review. PMID:25496905

Maniam J, Antoniadis C, Morris MJ (2014) Early-Life Stress, HPA Axis Adaptation, and Mechanisms Contributing to Later Health Outcomes.  Frontiers in Endocrinology (Lausanne) 13;5:73. doi: 10.3389/fendo.2014.00073  Review PMID:24860550

Harith HH, Morris MJ, Kavurma MM.  (2013).  On the TRAIL of obesity and diabetes.  Trends in Endocrinology and Metabolism, vol. 24, no. 11, pp. 578 - 587, http://dx.doi.org/10.1016/j.tem.2013.07.001 PMID:23948591

Maniam J, Morris MJ (2012). The link between stress and feeding behaviour. Neuropharmacology.  63 (1):97-110 PMID:22710442

Velkoska E & Morris MJ (2011) The mechanisms behind early life nutrition and adult disease outcome. World J Diabetes; 2(8):127-132. PMID: 21954416

Morris MJ. (2009) Early life influences on obesity risk – maternal overnutrition and programming of obesity Expert Opinion Endocrinology Metabolism 4(6) 625-637 invited review PMID:30780787

Morris MJ. (2008) Cardiovascular and metabolic effects of obesity Clin Exp Physiol Pharmacol 35(4), 416-419 Invited review PMID:18307732

Esler M, Alvarenga M, Lambert G, Kaye D, Hastings J, Jennings G, Morris M, Schwarz R, Richards J. (2004) Cardiac sympatheticnerve biology and brain monoamine turnover in panic disorder. Ann N Y Acad Sci. 1018, 505-514.  Review PMID:15240408

• 23/12/19 - The article on Dr Michael Kendig and Professor Margaret Morris' study was named one of UNSW’s most read medicine stories of 2019 
• 28/09/19 - Interviewed on Weekend Breakfast show, 2SER radio, Professor Margaret Morris talked about Junk food may be affecting your memory 
• 19/09/19 - An article on Dr Michael Kendig and Professor Margaret Morris' study was published in UNSW Newsroom. Poor diet may affect long-term spatial memory, UNSW study finds
• 04/06/19 - Commentary for Nutrition Australia: Sugar Drinks Fall Flat
• 11/05/19 - Professor Margaret Morris and Dr Michael Kendig's article in The Conversation was republished in the NZ Herald. Why eating certain foods could make you smarter
• 02/04/19 - Professor Margaret Morris was interviewed by 2ser radio to discuss the links between diet and brain function. Listen to the 6 minute interview here: Can eating certain food make you smarter? 
• 25/03/19 - Article published in The Conversation  Health check: can eating certain foods make you smarter?

• 26/10/18 - Coverage on Time for Kids. Food for thought
• 05/08/18 - Radio interview on 'Science on Sundays', ABC radio. Diet and behaviour - Gut biome 
• 18/07/18 - Radio interview on 'Drive', ABC Radio. Diet and gut microbiome
• 07/06/18 - Coverage on Science News for Students. Belly bacteria can shape mood and behavior
• 01/01/18 - Coverage on The Age, Sydney Morning Herald. What does sugar do to your brain

• November/ December 2017 - Coverage on HCF members newsletter. How important is the gut microbiome
• November 2017 - Science in Schools Interview at SFN, Washington. Diet, gut microbiome and Behaviour
• Research on reversing negative effects of maternal obesity. Coverage on Scientific Reports 2017; Science Daily [08/11/17]; New Straits Times [09/11/17]; International Business Times [10/11/17]; The Health site, Healthy Start Workforce project (NZ) [14/11/17], amongst others
• 17/03/17 - Radio interview on 'Healthy-lifestyle', Omny.fm. Whether probiotics are always good for your health?
• 24/02/17 - Coverage on SBS Food. Listen to your gut: do probiotics really work?

• 14/10/16 - Article published in The Conversation Fat or thin: can the bacteria in our gut affect our eating habits and weight? 
• 16/02/16 - Article published in The Conversation  Sugar may be as damaging to the brain as extreme stress or abuse
• 20/01/16 - Article published in The Conversation  Eating healthily during the week but bingeing on weekends is not OK for your gut

• 28/07/15 - Coverage on Medical News Today. High-fat maternal diet changes newborn heart ’tastebuds
• 06/07/15 - Margaret Morris interviewed for comment: COSMOS News- Life Sciences. The obesity fighting mushroom
• 23/05/15 - Coverage on Weekend Gold Coast Bulletin. Granny’s ongoing diet gift.
  
• 23/05/15 - Coverage on Daily Telegraph Sydney. Grandma’s diet link to health of grandkids

• 11/09/14 - The Morning Show, Channel  7 interviews Margaret Morris: The science of junk food. 
• 02/09/14 - Coverage on Asian Scientist. How junk food changes the brain
• 29/08/14 - Coverage on Food Navigator​​​​​​. Junk food could reduce appetite for healthier balanced diet
• 28/08/14 - Coverage on Science 2.0. Mom was almost right: junk food will spoil your appetite
• 27/08/14 - Coverage on Daily Mail UK. Is this why we’re all so fat
• 27/08/14 - Coverage on Medical Daily. Eating junk food may cause you to lose your appetite 
• 21/04/14 - Coverage on Medibank magazine. Junk food and your memory

• 20/12/13 - Coverage on ACB Active. Junk food can harm your memory.  
• 18/12/13 - Coverage on Australian Food News. Foods that harm memory in a week
• 18/12/13 - Coverage on University Herald. A week of junk food causes Memory Loss.
• 17/12/13 - Coverage on Business Insider. Study finds high fat and sugar diet reduces brain function.
• 28/11/13 - Coverage on The Daily Telegraph. Fitting in to dad’s genes.
• 28/11/13 - Coverage on Cairns Post. Fat dads warned of weighty offspring
• 03/04/13 -Coverage on The Daily Telegraph. Animals mimic human love of junk food

09/02/12 - Article published in The Conversation  Exercise can undo the ailments obese mothers hand down to children

Farewell dinner for Kelly - 8 Jan 2020

End of year dinner 2019