Exercise and Skeletal Muscle
Skeletal muscle metabolism and function is influenced by a variety of enzymes, transport and signalling proteins. Exercise training has a great capacity to influenced skeletal muscle function. The research interests in this group lie in quantifying adaptations in skeletal muscle to exercise and diet. Specifically we aim to examine various gene/protein adaptations to resistance and endurance type training. We aim to generate further knowledge about how exercise affects skeletal muscle and apply this knowledge to the study of age related muscle atrophy, metabolic disease and exercise performance.
Current Projects
- The effects of exercise on ACTN3 gene and protein expression in cyclists
- Effects of exercise in hypoxia on skeletal muscle oxidative capacity gene and protein expression
- The interaction of diet and exercise on myogenic factors in skeletal muscle
Members of the Research Group
Dr David Bentley
Potential honours and masters students are encouraged to contact David Bentley.
Collaborators
Dr Nigel Turner (Garvan Medical Research Institute, Sydney, Australia)
Asoc Prof David Cameron Smith (Deakin University, Melbourne, Australia)
Prof Jacques Mercier; Dr Gregoire Millet (Montpellier University, France)
Selected Publications
Roels, B.,
Bentley, D.J., Thomas, C.,
Mercier, J. and
Millet, G. The effects of intermittent hypoxic training on anaerobic performance and monocarboxylate transporters in well-trained athletes
Bentley, D.J., Roels, B.,
Mercier, J. ,
Millet, G. and
Cameron-Smith, D. The effects of high intensity training of muscle myogenic factors in trained cyclists
Roels, B., Thomas, C.,
Bentley, D. J.,
Mercier, J. and
Millet, G. Effects of intermittent hypoxic training on mitochondrial respiration in human permeabilized muscle fibers.
Journal of Applied Physiology
Helge, J.W.,
Bentley, D.J., Schjerling, P., Willer, M., Gibala, M.J., Franch, J., Laliena, M.A.T., Daugaard, J.R., Kiens B. and Andersen, J.L. Fat diet and training: effects on PPAR protein and mRNA expression.
Acta Physiologica Scandinavica
Bickham, D.C.,
Bentley, D.J., Le Rossignol, P.F. and
Cameron-Smith, D. The effects of sprint training on skeletal muscle MCT protein and mRNA expression in middle distance runners.
European Journal of Applied Physiology