Browse Research Interests

Ageing
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Arthritis / Rheumatology
Biochemistry
	Dr John Hunt     School of Medical Sciences - Department of Pathology Statement of Interests: My research interests focus on mast cell biology and the discovery and molecular characterisation of novel mast cell proteases. We have recently discovered a number of novel human mast cell tryptases, and we are currently determining their substrate specificity. Another aspect of our work involves the characterisation of factors that control the biology of mast cells. We have demonstrated that IL-15 is one of the most potent mast cell attractants yet reported, and aslo acts to upregulate the expression of ubiquitin-protein ligase 3B, matrix metalloproteinase 9 (MMP9) and apolipoprotein CI (ApoC1) by mast cells. More...
	Dr Stephen Palmer     School of Medical Sciences Statement of Interests: 1.Understanding the role of the gene Gtf2ird1 in brain development and human behaviour and its contribution towards the characteristic features of Williams-Beuren syndrome. 2. Understanding the gene regulatory networks involved in the control of muscle fibre type in order to develop strategies to combat the effects of disease and ageing. More...
Biological Anthropology
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