Browse Research Interests

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Hide details for [<a name="Ophthalmology"></a><A HREF="../page/Research%20Interests%20Listing?OpenDocument&start=1&count=1000&E Ophthalmology
Dr Nick Di Girolamo
    School of Medical Sciences - Department of Pathology
    Statement of Interests:
    Our current research program focuses on understanding how excessive solar ultraviolet radiation triggers diseases of the eye including pterygia, tumours of the limbus and conjunctiva, and how specific enzymes called the matrix metalloproteinases (MMPs) contribute to the development of such lesions in man. These studies utilize cell culture models and fresh human tissue specimens. The second arm of our research program focuses on identifying, isolating and cultivating human fetal and adult corneal stem cells to help us understand how the ocular surface is replenished under normal physiological conditions and following trauma and to devise alternative transplantation strategies to treat patients with corneal stem cell deficiencies. The third arm of our research program focuses on associations of single nucleotide polymorphisms in MMP genes with common epithelial tumours such as colorectal, prostate, and breast. We have recently identified one such polymorphism in the collahenase-1 (MMP-1) gene promoter as a potential prognostic indicator in patients with colorectal carcinoma.
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Dr Mark Hill
    School of Medical Sciences - Department of Anatomy
    Statement of Interests:

    My current research in the Cell Biology Laboratory is looking at the skeleton within each cell and the biological mechanisms use to change and regulate shape. The description of these mechanisms leads to a better understanding of, and perhaps influence on, these changes occurring in disease, development and during cell repair. Analysis in the School employs the powerful tools of molecular biology, tissue culture and image analysis techniques.
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Show details for [<a name="Stem Cells"></a><A HREF="../page/Research%20Interests%20Listing?OpenDocument&start=1&count=1000&Expa Stem Cells
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Show details for [<a name="Virology"></a><A HREF="../page/Research%20Interests%20Listing?OpenDocument&start=1&count=1000&Expand Virology

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