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Dr Barbara Cameron
    
School of Medical Sciences - Department of Pathology
Statement of Interests:
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Professor David Davies
    
School of Medical Sciences
Statement of Interests:
Anti-neutrophil cytoplasmic antibodies and the pathology of small vessel vasculitis. The pathogenesis of proteinuria The pathology and pathogenesis of renal medullary necrosis. Investigations into the efficiency and efficacy of pathology testing in modern medical practice. Quality assurance in anatomical pathology including use of virtual microscopy and development of methods for assessment of diagnositc performance.
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Dr John Hunt
    
School of Medical Sciences - Department of Pathology
Statement of Interests:
My research interests focus on mast cell biology and the discovery and molecular characterisation of novel mast cell proteases. We have recently discovered a number of novel human mast cell tryptases, and we are currently determining their substrate specificity. Another aspect of our work involves the characterisation of factors that control the biology of mast cells. We have demonstrated that IL-15 is one of the most potent mast cell attractants yet reported, and aslo acts to upregulate the expression of ubiquitin-protein ligase 3B, matrix metalloproteinase 9 (MMP9) and apolipoprotein CI (ApoC1) by mast cells.
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Professor Andrew Lloyd
    
School of Medical Sciences - Department of Pathology
Statement of Interests:
The goal of the research groups which are led by Professor Lloyd is to understand the cellular and molecular basis of inflammatory processes in human infectious diseases. In particular, Professor Lloyd's research groups are seeking to define the role of cytokines, notably the chemoattractant cytokines (chemokines) in regulation of lymphocyte trafficking. The groups are focussed on studies of the pathogenesis of hepatitis C infection, and the characteristics of the host response to other infections includi ng Epstein-Barr virus, Ross River virus and Coxiella burnetii - the causative agent of Q fever. The scope of the research extends from laboratory studies of the basic biology of genes relevant to disease pathogenesis through to clinical and epidemiological studies in humans. The research includes cellular and molecular immunology techniques, and includes in vitro as well as in vivo studies in animal models of disease
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Dr David Simar
    
School of Medical Sciences - Exercise Physiology Program
Statement of Interests:
My research interests are mainly focused on the characterisation of metabolic dysfunctions in the immune system and skeletal muscles as well as the critical role played by inflammation in the development of those alterations in metabolic and immune conditions.
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