Browse Research Interests

Ageing
Allergy
Anatomy
Arthritis / Rheumatology
Biochemistry
Biological Anthropology
Biomedical Engineering
Cancer
Cardiology and Vascular Disease
Cell Biology and Gene Regulation
Clinical Governance
Clinical Research
Diabetes
Disease Modelling
Embryology
Endocrinology
Epidemiology
Gastrointestinal Diseases
Genetics - Genome Analysis
	Dr Romain Barres     School of Medical Sciences - Exercise Physiology Program Statement of Interests: Type 2 diabetes (T2DM) remains a complex and multifaceted disease, the exact causes of which have yet to be resolved. While genetic predisposition can contribute to the development of T2DM, diet and physical activity can also have a positive impact on insulin sensitivity. Epigenetic modifications provide a mechanism by which external environmental factors such as exercise and diet can modify genetic predisposition for health and disease. My research activity is focused on the mechanisms underlying metabolic disorders with particular attention on human skeletal muscle. We identified that changes in the metabolic environment could lead to a dynamic epigenetic modulation of genes that have been implicated in the control of insulin sensitivity and the development of T2DM and related metabolic disorders. More...
	Dr Yue Huang     School of Medical Sciences Statement of Interests: Current research is focus on Parkinson’s disease and related disorders, with a particular interest in molecular biomarkers for clinical diagnosis and prognosis of Parkinson’s disease and early detection of dementia syndrome; cross cultural comparison on epidemiological, clinical and pathological features of the disorders; as well as human brain tissue analysis on the formation and maturation of disease characteristic pathological lesions (Lewy bodies of Parkinson’s disease, glial cytoplasmic inclusions of multiple system atrophy and coil bodies of progressive supranuclear palsy). More...
	Dr John Hunt     School of Medical Sciences - Department of Pathology Statement of Interests: My research interests focus on mast cell biology and the discovery and molecular characterisation of novel mast cell proteases. We have recently discovered a number of novel human mast cell tryptases, and we are currently determining their substrate specificity. Another aspect of our work involves the characterisation of factors that control the biology of mast cells. We have demonstrated that IL-15 is one of the most potent mast cell attractants yet reported, and aslo acts to upregulate the expression of ubiquitin-protein ligase 3B, matrix metalloproteinase 9 (MMP9) and apolipoprotein CI (ApoC1) by mast cells. More...
	Dr Stephen Palmer     School of Medical Sciences Statement of Interests: 1.Understanding the role of the gene Gtf2ird1 in brain development and human behaviour and its contribution towards the characteristic features of Williams-Beuren syndrome. 2. Understanding the gene regulatory networks involved in the control of muscle fibre type in order to develop strategies to combat the effects of disease and ageing. More...
Immunology
Infectious Diseases
Inflammation
Injury
Lipids
Medical Education
Medical Informatics
Metabolism
Molecular Structure & Drug Design
Neurodegenerative Diseases
Neurology
Neuropsychology
Neuroscience
Neurotrauma
Obesity
Obstetrics / Gynaecology
Ophthalmology
Orthopaedics
Pain
Pathology
Pharmacology
Physiology
Preventive Medicine
Proteomics
Psychiatry
Pulmonary Disease
Rehabilitation
Renal Disease
Stem Cells
Transplantation
Virology