Browse Research Interests

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Hide details for [<a name="Gastrointestinal Diseases"></a><A HREF="../page/Research%20Interests%20Listing?OpenDocument&start=1& Gastrointestinal Diseases
Associate Professor Paul Bertrand
    School of Medical Sciences
    Statement of Interests:
    The goal of my research is to understand the neuronal basis of disease with an emphasis on the compounds ATP & serotonin (5‑HT) and the roles they play in neurotransmission & sensory transduction. My laboratory focuses on the neurophysiology of the gastrointestinal tract using electrophysiological and electrochemical methods.
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Dr Rebecca Bertrand
    School of Medical Sciences
    Statement of Interests:
    The gastrointestinal tract turns out to be quite a complicated organ. You might think it's just absorb this and poop that, but how does that really happen? A lot of it is controlled by a massive network of neurons located within the gut (called the enteric nervous system) - that's right, the brain isn't the only place where a whole bunch of neurons live. We investigate how this network of neurons manages to control the workings of the intestine without any help from the brain. We record from individual neurons (intracellular electrophysiology) to see how they communicate with their neighbours and how the neighbours talk to them (synaptic transmission). We also look at it from the whole organ level.
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Professor Elizabeth Burcher
    School of Medical Sciences - Department of Pharmacology
    Statement of Interests:

    a) neurochemicals in human intestine: alterations in disease. b) neurochemicals in the human bladder: relevance to urinary incontinence. c) urothelium of the pig bladder as a model for human bladder studies.
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Professor Nick Hawkins
    School of Medical Sciences - Department of Pathology
    Statement of Interests:

    In terms of colorectal (bowel) cancer, the work of the laboratory is focussed on understanding the molecular changes that drive the process of cancer development. There is an emphasis on the role of DNA methylation in the development of bowel cancer, and on the correlation between microscopic appearances of cancer, and the key genetic changes occuring in the tumour.
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Dr Lu Liu
    School of Medical Sciences - Department of Pharmacology
    Statement of Interests:
    Neurochemicals and receptors in regulation of gut function
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